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List of works by Claudia Schoch

21q22 balanced chromosome aberrations in therapy-related hematopoietic disorders: report from an international workshop

scientific article published in April 2002

A combination of cytomorphology, cytogenetic analysis, fluorescence in situ hybridization and reverse transcriptase polymerase chain reaction for establishing clonality in cases of persisting hypereosinophilia.

scientific article

A comparison of donor lymphocyte infusions or imatinib mesylate for patients with chronic myelogenous leukemia who have relapsed after allogeneic stem cell transplantation.

scientific article

A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia

scientific article published in November 2002

A new prognostic score for patients with acute myeloid leukemia based on cytogenetics and early blast clearance in trials of the German AML Cooperative Group

scientific article published on April 2004

AML M3 and AML M3 variant each have a distinct gene expression signature but also share patterns different from other genetically defined AML subtypes.

scientific article published in June 2005

AML with 11q23/MLL abnormalities as defined by the WHO classification: incidence, partner chromosomes, FAB subtype, age distribution, and prognostic impact in an unselected series of 1897 cytogenetically analyzed AML cases

scientific article

Acute myeloid leukemia (AML) with t(8;21)(q22;q22) relapsing as AML with t(3;21)(q26;q22).

scientific article

Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile

scientific article

Acute myeloid leukemia: treatment over 60.

scientific article

Acute myeloid leukemias with reciprocal rearrangements can be distinguished by specific gene expression profiles

scientific article

Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

scientific article

Analysis of site-specific transgene integration following cotransduction with recombinant adeno-associated virus and a rep encodingplasmid

scientific article published in February 2003

Blast count and cytogenetics correlate and are useful parameters for the evaluation of different phases in chronic myeloid leukemia.

scientific article

CD40L stimulation enhances the ability of conventional metaphase cytogenetics to detect chromosome aberrations in B-cell chronic lymphocytic leukaemia cells

scientific article

CS-1, a novel c-kithi+ acute myeloid leukemia cell line with dendritic cell differentiation capacity and absent immunogenicity

scientific article published on June 2003

Clinical trial of valproic acid and all-trans retinoic acid in patients with poor-risk acute myeloid leukemia

scientific article

Comparison of mRNA abundance quantified by gene expression profiling and percentage of positive cells using immunophenotyping for diagnostic antigens in acute and chronic leukemias

scientific article published on November 2006

Computer aided analysis of additional chromosome aberrations in Philadelphia chromosome positive acute lymphoblastic leukaemia using a simplified computer readable cytogenetic notation

scientific article

Conventional cytogenetics of myeloproliferative diseases other than CML contribute valid information

scientific article published on 4 February 2005

Correlation of protein expression and gene expression in acute leukemia

scientific article published on September 2003

Cytogenetics in acute myeloid leukemia

scientific article

Detailed analysis of FLT3 expression levels in acute myeloid leukemia.

scientific article

Detection of minimal residual disease in unselected patients with acute myeloid leukemia using multiparameter flow cytometry for definition of leukemia-associated immunophenotypes and determination of their frequencies in normal bone marrow.

scientific article

Determination of relapse risk based on assessment of minimal residual disease during complete remission by multiparameter flow cytometry in unselected patients with acute myeloid leukemia

scientific article published on 29 July 2004

Diagnostic tool for the identification of MLL rearrangements including unknown partner genes

scientific article

Distinct gene expression patterns associated with FLT3- and NRAS-activating mutations in acute myeloid leukemia with normal karyotype

scientific article

Distinct sequences on 11q13.5 and 11q23-24 are frequently coamplified with MLL in complexly organized 11q amplicons in AML/MDS patients

scientific article published on April 2004

Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease

scientific article

Early blast clearance by remission induction therapy is a major independent prognostic factor for both achievement of complete remission and long-term outcome in acute myeloid leukemia: data from the German AML Cooperative Group (AMLCG) 1992 Trial

scientific article

Early prediction of response in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) treated with imatinib

scientific article published on 23 October 2003

Effect of histone deacetylase inhibitor valproic acid on progenitor cells of acute myeloid leukemia

scientific article published on April 2007

Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies

scientific article published on 28 August 2003

FLT3 length mutations as marker for follow-up studies in acute myeloid leukaemia

scientific article published on January 2004

Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).

scientific article

Functional analysis of apoptosis induction in acute myeloid leukaemia-relevance of karyotype and clinical treatment response

scientific article published in August 2004

Further correlations of morphology according to FAB and WHO classification to cytogenetics in de novo acute myeloid leukemia: a study on 2,235 patients.

scientific article

Gain of 9p due to an unbalanced rearrangement der(9;18): a recurrent clonal abnormality in chronic myeloproliferative disorders

scientific article published on July 2005

Gene expression profiling as a diagnostic tool in acute myeloid leukemia

scientific article published in January 2004

Gene expression profiling as a tool for the diagnosis of acute leukemias ⬇️

scientific article published on October 1, 2003

Impact of FLT3 mutations and promyelocytic leukaemia-breakpoint on clinical characteristics and prognosis in acute promyelocytic leukaemia.

scientific article

Implications of NRAS mutations in AML: a study of 2502 patients

scientific article

Increased risk for therapy-associated hematologic malignancies in patients with carcinoma of the breast and combined homozygous gene deletions of glutathione transferases M1 and T1.

scientific article published in March 2002

Isochromosome breakpoints on 17p in medulloblastoma are flanked by different classes of DNA sequence repeats

scientific article (publication date: 2006)

Isolated epidural chloroma with translocation t(15; 17) successfully treated with chemotherapy and all-trans-retinoic acid

scientific article published in August 2003

KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival

scientific article published on 27 October 2005

Loss of genetic material is more common than gain in acute myeloid leukemia with complex aberrant karyotype: a detailed analysis of 125 cases using conventional chromosome analysis and fluorescence in situ hybridization including 24-color FISH.

scientific article published on September 2002

Modern diagnostics in acute leukemias

scientific article

Molecular characterization of acute leukemias by use of microarray technology

scientific article published on August 2003

Monitoring of minimal residual disease in acute myeloid leukemia

scientific article

Mutation analysis of the Nijmegen breakage syndrome gene (NBS1) in nineteen patients with acute myeloid leukemia with complex karyotypes.

scientific article published in November 2003

New score predicting for prognosis in PML-RARA+, AML1-ETO+, or CBFBMYH11+ acute myeloid leukemia based on quantification of fusion transcripts.

scientific article

Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype

scientific article

Prognostic impact of early response to induction therapy as assessed by multiparameter flow cytometry in acute myeloid leukemia.

scientific article

Rapid diagnostic approach to PML-RARalpha-positive acute promyelocytic leukemia

scientific article published in January 2002

Re: Prognostic significance of a short sequence insertion in the MCL-1 promoter in chronic lymphocytic leukemia.

scientific article

Response and resistance in 300 patients with BCR-ABL-positive leukemias treated with imatinib in a single center: a 4.5-year follow-up

scientific article published in April 2005

Reverse transcriptase-polymerase chain reaction based quantification of the combined MDS-EVI1/EVI1 gene in acute myeloid leukemia.

scientific article

Risk assessment by monitoring expression levels of partial tandem duplications in the MLL gene in acute myeloid leukemia during therapy.

scientific article

Role of gene expression profiling for diagnosing acute leukemias.

scientific article

The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner

scientific article

The influence of age on prognosis of de novo acute myeloid leukemia differs according to cytogenetic subgroups.

scientific article published in September 2004

The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2

scientific article (publication date: April 2005)

Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2-PDGFRA fusion gene

scientific article published in October 2006

Treatment of AML in biological subgroups

scientific article

Treatment of older patients with AML.

scientific article

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