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List of works by Max Löhning

"Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses

scientific article

A GATA-3 binding site in the first intron of the interleukin-4 gene defines a critical element for the memory expression of interleukin-4 in Th lymphocytes

A critical control element for interleukin-4 memory expression in T helper lymphocytes

scientific article

Aggravation of viral hepatitis by platelet-derived serotonin

scientific article published on 30 May 2008

Autoregulation of Th1-mediated inflammation by twist1.

scientific article published on 28 July 2008

B Cells Negatively Regulate the Establishment of CD49b(+)T-bet(+) Resting Memory T Helper Cells in the Bone Marrow

scientific article published on 2 February 2016

CD49b-dependent establishment of T helper cell memory.

scientific article published on 30 July 2013

CD49b/CD69-Dependent Generation of Resting T Helper Cell Memory.

scientific article published on 10 July 2013

Commitment of individual Th1-like lymphocytes to expression of IFN-gamma versus IL-4 and IL-10: selective induction of IL-10 by sequential stimulation of naive Th cells with IL-12 and IL-4 ⬇️

scientific article published on September 15, 1998

Cytokine memory of T helper lymphocytes

scientific article

Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection

scientific article

Detection and isolation of cytokine secreting cells using the cytometric cytokine secretion assay

scientific article published on 01 February 2002

Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity.

scientific article published on 7 February 2010

Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-γ production.

scientific article

Endotoxins prevent murine IgE production, T(H)2 immune responses, and development of airway eosinophilia but not airway hyperreactivity

scientific article

Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus

scientific article

Enhanced Cell Division Is Required for the Generation of Memory CD4 T Cells to Migrate Into Their Proper Location

scientific article published on 01 January 2019

Eosinophils are required for the maintenance of plasma cells in the bone marrow

scientific article published on 9 January 2011

Establishment of memory for IL-10 expression in developing T helper 2 cells requires repetitive IL-4 costimulation and does not impair proliferation

scientific article

Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10.

scientific article published on January 2003

GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model

scientific article

Human monocytes and macrophages differ in their mechanisms of adaptation to hypoxia

scientific article published on 7 August 2012

IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGFβ Release

scientific article

IL-33 in T Cell Differentiation, Function, and Immune Homeostasis

scientific article published on 4 April 2016

Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses

scientific article published on 28 October 2015

Individual T helper cells have a quantitative cytokine memory

scientific article

Inducible costimulator-positive T cells are required for allergen-induced local B-cell infiltration and antigen-specific IgE production in lung tissue

scientific article published in October 2004

Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions

scientific article published on 14 January 2010

Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation

scientific article published on 01 March 2005

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors.

scientific article

Macrophage migration inhibitory factor counterregulates dexamethasone-mediated suppression of hypoxia-inducible factor-1 alpha function and differentially influences human CD4+ T cell proliferation under hypoxia

scientific article published on 17 December 2010

Manipulation of the balance between Th2 and Th2/1 hybrid cells affects parasite nematode fitness in mice

scientific article published on 24 October 2018

Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth

scientific article published on 01 June 2022

Memory CD8+ T Cell Protection From Viral Reinfection Depends on Interleukin-33 Alarmin Signals

scientific article published on 07 August 2019

NK cell receptor NKG2D enforces proinflammatory features and pathogenicity of Th1 and Th17 cells

scientific article published on 01 August 2020

Professional memory CD4+ T lymphocytes preferentially reside and rest in the bone marrow.

scientific article

Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy.

scientific article

Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression

scientific article published on April 2010

Single-cell transcriptomes of murine bone marrow stromal cells reveal niche-associated heterogeneity

scientific article published on 07 June 2019

Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression

scientific article published on March 2017

Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.

scientific article

Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage

scientific article

Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism.

scientific article

T cells can mediate viral clearance from ependyma but not from brain parenchyma in a major histocompatibility class I- and perforin-independent manner

scientific article published on 30 March 2010

T-bet expression by Th cells promotes type 1 inflammation but is dispensable for colitis.

scientific article published on 17 February 2016

T-bet- and STAT4-dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses.

scientific article

T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function

scientific article

TH17 cells express ST2 and are controlled by the alarmin IL-33 in the small intestine

scientific article published on 15 February 2017

Th2/1 Hybrid Cells Occurring in Murine and Human Strongyloidiasis Share Effector Functions of Th1 Cells

scientific article

The alarmin IL-33 promotes regulatory T-cell function in the intestine

scientific article

The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses

scientific article

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

scientific article published on 10 October 2010

Tolerance induction with T cell-dependent protein antigens induces regulatory sialylated IgGs.

scientific article published on 12 April 2012

Transcriptional control networks of cell differentiation: insights from helper T lymphocytes

scientific article

Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity.

scientific article published on 5 June 2014

Unlike αβ T cells, γδ T cells, LTi cells and NKT cells do not require IRF4 for the production of IL-17A and IL-22.

scientific article published on 17 October 2012

Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes

scientific article

Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression.

scientific article

miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.

scientific article published on 22 January 2015

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