Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Janet L. Smith

A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ

scientific article published on 21 June 2018

A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.

scientific article published on 2 November 2017

A new generation of crystallographic validation tools for the protein data bank

scientific article

Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate

scientific article published on 29 August 2016

Biochemical and Structural Characterization of Germicidin Synthase: Analysis of a Type III Polyketide Synthase That Employs Acyl-ACP as a Starter Unit Donor ⬇️

scientific article published on April 23, 2012

Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide Hydrolase

scientific article

Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module

scientific article published on 08 May 2018

Catalytic Core of Alphavirus Nonstructural Protein nsP4 Possesses Terminal Adenylyltransferase Activity

scientific article (publication date: October 2006)

Conformational switch triggered by  -ketoglutarate in a halogenase of curacin A biosynthesis

scientific article

Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway

scientific article

Crystal structure of imidazole glycerol-phosphate dehydratase: duplication of an unusual fold

scientific article

Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching

scientific article

Cyanobacterial Polyketide Synthase Docking Domains: A Tool for Engineering Natural Product Biosynthesis

scientific article

Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase

scientific article

Extended surface for membrane association in Zika virus NS1 structure

scientific article

Flexibility in Nucleic Acid Binding Is Central to APOBEC3H Antiviral Activity

scientific article published on 26 November 2019

Functional Dissection of the Bacillus subtilis pur Operator Site

scientific article

Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase

scientific article published on 23 September 2019

GNAT-like strategy for polyketide chain initiation

scientific article

Identification of Inhibitors of Yellow Fever Virus Replication Using a Replicon-Based High-Throughput Assay

scientific article

Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme

scientific article

Insights into the reactivation of cobalamin-dependent methionine synthase

scientific article

Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta ⬇️

scientific article published on 03 December 2018

Metal active site elasticity linked to activation of homocysteine in methionine synthases

scientific article

Metamorphic enzyme assembly in polyketide diversification

scientific article

Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase

scientific article published on 12 September 2018

Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway

scientific article published on 16 January 2020

Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis

scientific article published on November 2009

Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis

scientific article published on 27 November 2019

Sacrificial Cobalt-carbon Bond Homolysis in Coenzyme B12 as a Cofactor Conservation Strategy

scientific article published on 08 October 2018

Stereodivergent, Chemoenzymatic Synthesis of Azaphilone Natural Products

scientific article published on 06 November 2019

Structural Basis for Binding Specificity between Subclasses of Modular Polyketide Synthase Docking Domains

scientific article

Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase

scientific article

Structural Basis of Functional Group Activation by Sulfotransferases in Complex Metabolic Pathways ⬇️

scientific article published on September 26, 2012

Structural Basis of Polyketide Synthase O-Methylation

scientific article published on 03 December 2018

Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction

scientific article

Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine  -synthase

scientific article

Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolor

scientific article

Structure and Functional Analysis of RifR, the Type II Thioesterase from the Rifamycin Biosynthetic Pathway

scientific article

Structure and activity of DmmA, a marine haloalkane dehalogenase ⬇️

scientific article published on January 4, 2012

Structure of the Cytochrome b 6 f Complex of Oxygenic Photosynthesis: Tuning the Cavity ⬇️

scientific article published on October 2, 2003

Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing

scientific article

Structure of the Rift Valley fever virus nucleocapsid protein reveals another architecture for RNA encapsidation

scientific article

Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences

scientific article published on 12 November 2019

Structure-guided insights on the role of NS1 in flavivirus infection

scientific article

Terminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis: STRUCTURE OF A DECARBOXYLATING THIOESTERASE

scientific article

The Purine Repressor of Bacillus subtilis: a Novel Combination of Domains Adapted for Transcription Regulation

scientific article

The dictyostelium kinome--analysis of the protein kinases from a simple model organism.

scientific article

Toward understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerolphosphate synthase: crystal structures of a ternary complex and the free enzyme

scientific article

Paulina is supported by:

About Paulina

Help