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List of works by Heike Grassmé

Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death

scientific article published on November 13, 2010

Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis

scientific article published on 25 January 2015

Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs

scientific article (publication date: 16 June 2013)

Alterations in ceramide concentration and pH determine the release of reactive oxygen species by Cftr-deficient macrophages on infection

scientific article published on 29 March 2010

Bacterial Infections and Ceramide

scientific article published on January 1, 2013

Biological aspects of ceramide-enriched membrane domains

scientific article published on 31 March 2007

CD95 Signaling via Ceramide-rich Membrane Rafts

scientific article published in Journal of Biological Chemistry

CD95 rapidly clusters in cells of diverse origins

scientific article

CFTR-dependent susceptibility of the cystic fibrosis-host to Pseudomonas aeruginosa

scientific article published on October 14, 2010

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

scientific article

Ceramide and cell death receptor clustering

scientific article

Ceramide and sphingosine in pulmonary infections

scientific article published on June 2015

Ceramide in Cystic Fibrosis

scientific article published on January 1, 2013

Ceramide in Pseudomonas aeruginosa infections and cystic fibrosis

scientific article published on 18 May 2010

Ceramide in bacterial infections and cystic fibrosis

scientific article

Ceramide inPseudomonas aeruginosa infections

Ceramide, membrane rafts and infections

scientific article published on 7 April 2004

Ceramide-mediated clustering is required for CD95-DISC formation

Ceramide: physiological and pathophysiological aspects

scientific article published on 11 April 2007

Clustering of CD40 ligand is required to form a functional contact with CD40.

scientific article

Crosstalk Between Sphingomyelinases and Reactive Oxygen Species in Mycobacterial Infection

scientific article published on 9 March 2017

Inhibition of Acid Sphingomyelinase by Antidepressants Counteracts Stress-Induced Activation of P38-Kinase in Major Depression

scientific article published on 19 December 2015

Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis

scientific article published on January 2016

Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fibrosis

scientific article

Melatonin Acts as an Antidepressant by Inhibition of the Acid Sphingomyelinase/Ceramide System

scientific article published on 11 July 2016

Membrane rafts in host-pathogen interactions

scientific article published on 8 August 2006

Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes

scientific article

Neutral sphingomyelinase in physiological and measles virus induced T cell suppression

scientific article

Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species and mitochondrial acid sphingomyelinase

scientific article

Regulation of Neuronal Stem Cell Proliferation in the Hippocampus by Endothelial Ceramide

scientific article published on August 2016

Regulation of Staphylococcus aureus Infection of Macrophages by CD44, Reactive Oxygen Species, and Acid Sphingomyelinase

scientific article

Regulation of hematogenous tumor metastasis by acid sphingomyelinase

scientific article

Regulation of the inflammasome by ceramide in cystic fibrosis lungs.

scientific article

Rhinoviruses infect human epithelial cells via ceramide-enriched membrane platforms

scientific article

Role of Janus-Kinases in Major Depressive Disorder

scientific article published on 3 August 2016

Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa

scientific article

Sphingolipids as targets for inhalation treatment of cystic fibrosis

scientific article

Sphingolipids in Major Depression

scientific article published on 19 December 2015

Staphylococcus aureus Alpha-Toxin Disrupts Endothelial-Cell Tight Junctions via Acid Sphingomyelinase and Ceramide

scientific article published on 30 October 2017

Staphylococcus aureus Survives in Cystic Fibrosis Macrophages, Forming a Reservoir for Chronic Pneumonia

scientific article published on 13 March 2017