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List of works by Bennard van Ravenzwaay

A 1-year toxicity study in dogs is no longer a scientifically justifiable core data requirement for the safety assessment of pesticides.

scientific article

A comparison of the embryonic stem cell test and whole embryo culture assay combined with the BeWo placental passage model for predicting the embryotoxicity of azoles

scientific article published on 11 January 2018

A developmental toxicity study of 3S, 3'S-Astaxanthin in New Zealand white rabbits

scientific article

A modular approach to the extended one-generation reproduction toxicity study. The outcome of an ECETOC Task Force and International ECETOC/ECVAM Workshop.

scientific article published in April 2009

A protocol to determine dermal absorption of xenobiotica through human skin in vitro

scientific article published on 5 July 2016

A short-term inhalation study protocol: designed for testing of toxicity and fate of nanomaterials

scientific article published in January 2014

A testing strategy for the identification of mammalian, systemic endocrine disruptors with particular focus on steroids

scientific article published on April 24, 2012

A tiered approach to systemic toxicity testing for agricultural chemical safety assessment

scientific article

A transcriptomic approach for evaluating the relative potency and mechanism of action of azoles in the rat Whole Embryo Culture

scientific article published on 29 September 2017

Acetylcholinesterase measurement in various brain regions and muscles of juvenile, adolescent, and adult rats

scientific article

Activities of xenobiotic metabolizing enzymes in rat placenta and liver in vitro

scientific article published in March 2016

Additional Histopathologic Examination of the Lungs from a 3-Month Inhalation Toxicity Study with Multiwall Carbon Nanotubes in Rats ⬇️

scientific article published on April 9, 2013

Anti-androgenicity can only be evaluated using a weight of evidence approach

scientific article published on 31 October 2013

Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: Substantiating test strategies with data from routine studies ⬇️

scientific article published on August 30, 2012

Applicability of rat precision-cut lung slices in evaluating nanomaterial cytotoxicity, apoptosis, oxidative stress, and inflammation.

scientific article published on 29 December 2013

Application of short-term inhalation studies to assess the inhalation toxicity of nanomaterials

scientific article

Assessment of combinations of antiandrogenic compounds vinclozolin and flutamide in a yeast based reporter assay ⬇️

scientific article published on May 18, 2011

Assessment of skin sensitization under REACH: A case report on vehicle choice in the LLNA and its crucial role preventing false positive results

scientific article

Assessment of the analgesic dipyrone as a possible (anti)androgenic endocrine disruptor

scientific article published on 28 December 2017

Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface carbon black

scientific article published on 17 June 2013

Comparative short-term inhalation toxicity of five organic diketopyrrolopyrrole pigments and two inorganic iron-oxide-based pigments

scientific article published on 7 July 2016

Computer models versus reality: how well do in silico models currently predict the sensitization potential of a substance

scientific article published on 30 September 2013

Developmental toxicity of polyethylene glycol-g-polyvinyl alcohol grafted copolymer in rats and rabbits ⬇️

scientific article published on January 5, 2013

Editorial: Applying 'omics technologies in chemicals risk assessment

scientific article published in December 2017

Effect of estrogenic binary mixtures in the yeast estrogen screen (YES).

scientific article published on 11 July 2014

Effects of SiO₂, ZrO₂, and BaSO₄ nanomaterials with or without surface functionalization upon 28-day oral exposure to rats

scientific article

Embryotoxic and pharmacologic potency ranking of six azoles in the rat whole embryo culture by morphological and transcriptomic analysis

scientific article

Epigenetics and chemical safety - concluding remarks

scientific article published on 24 March 2014

Epoxiconazole-induced degeneration in rat placenta and the effects of estradiol supplementation

scientific article published on 29 April 2013

Erratum to “Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: Substantiating test strategies with data from routine studies” [Regul. Toxicol. Pharmacol. (2012) 402–414] ⬇️

scientific article published on April 1, 2013

Ethylbenzene: 4- and 13-week rat oral toxicity

scientific article published on 21 October 2006

Extended evaluation on the ES-D3 cell differentiation assay combined with the BeWo transport model, to predict relative developmental toxicity of triazole compounds

scientific article published on 6 June 2015

Flusilazole induces spatio-temporal expression patterns of retinoic acid-, differentiation- and sterol biosynthesis-related genes in the rat Whole Embryo Culture

scientific article published on 14 April 2016

Further experience with the local lymph node assay using standard radioactive and nonradioactive cell count measurements ⬇️

scientific article published on May 25, 2012

Green Toxicology: a strategy for sustainable chemical and material development

scientific article published on 4 April 2017

Guidance on the selection of cohorts for the extended one-generation reproduction toxicity study (OECD test guideline 443).

scientific article published on 28 May 2016

Gut Microbiota as Well as Metabolomes of Wistar Rats Recover within Two Weeks after Doripenem Antibiotic Treatment

scientific article published in 2023

Hexamoll® DINCH: Lack of in vivo evidence for obesogenic properties

scientific article published on 20 February 2018

Immunophenotyping does not improve predictivity of the local lymph node assay in mice

scientific article published on 3 September 2014

In vivo–in vitro comparison of acute respiratory tract toxicity using human 3D airway epithelial models and human A549 and murine 3T3 monolayer cell systems ⬇️

scientific article published on October 22, 2012

Initiatives to decrease redundancy in animal testing of pesticides

scientific article published on January 1, 2010

Intra- and inter-laboratory reproducibility and accuracy of the LuSens assay: A reporter gene-cell line to detect keratinocyte activation by skin sensitizers

scientific article published on 12 January 2016

Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals

scientific article

Intrinsic Xenobiotic Metabolizing Enzyme Activities in Early Life Stages of Zebrafish (Danio rerio).

scientific article

Investigation on the genotoxicity of different sizes of gold nanoparticles administered to the lungs of rats ⬇️

scientific article published on December 7, 2011

Investigations on the dose-response relationship of combined exposure to low doses of three anti-androgens in Wistar rats

scientific article published on 6 September 2017

Lacking applicability of in vitro eye irritation methods to identify seriously eye irritating agrochemical formulations: Results of bovine cornea opacity and permeability assay, isolated chicken eye test and the EpiOcular™ ET-50 method to classify a

scientific article

Metabolomics in toxicology and preclinical research

scientific article published on January 2013

Non-animal test methods for predicting skin sensitization potentials

scientific article published on 16 June 2012

Occurrence of Pineal Gland Tumors in Combined Chronic Toxicity/Carcinogenicity Studies in Wistar Rats

scientific article published on 9 March 2015

Octyl methoxycinnamate: two generation reproduction toxicity in Wistar rats by dietary administration

scientific article published in July 2005

Performance standards and alternative assays: Practical insights from skin sensitization ⬇️

scientific article published on December 29, 2012

Polyethylene glycol-g-polyvinyl alcohol grafted copolymer: Reproductive toxicity study in Wistar rats ⬇️

scientific article published on January 7, 2013

Polyethylene glycol–polyvinyl alcohol grafted copolymer: Study of the bioavailability after oral administration to rats ⬇️

scientific article published on January 12, 2013

Postnatal fate of prenatal-induced fetal alterations in laboratory animals

scientific article published on 14 April 2016

Prenatal toxicity of synthetic amorphous silica nanomaterial in rats

scientific article published on 18 April 2015

Putting the parts together: Combining in vitro methods to test for skin sensitizing potentials ⬇️

scientific article published on June 1, 2012

Refinement and reduction of acute oral toxicity testing: a critical review of the use of cytotoxicity data.

scientific article

Regulatory accepted but out of domain: In vitro skin irritation tests for agrochemical formulations

scientific article

Relevance of the 1-year dog study in assessing human health risks for registration of pesticides. An update to include pesticides registered in Japan

scientific article published on 08 September 2014

Relevance of xenobiotic enzymes in human skinin vitromodels to activate pro-sensitizers ⬇️

scientific article published on 03 April 2012

Risk assessment of endocrine disrupting chemicals – Introduction to this special issue ⬇️

scientific article published on October 15, 2013

Short-term rat inhalation study with aerosols of acrylic ester-based polymer dispersions containing a fraction of nanoparticles

scientific article published on 19 January 2012

Species Differences in Developmental Toxicity of Epoxiconazole and Its Relevance to Humans ⬇️

scientific article published on April 29, 2013

The Bovine Corneal Opacity and Permeability Test in Routine Ocular Irritation Testing and its Improvement within the Limits of OECD Test Guideline 437 ⬇️

scientific article published on March 1, 2011

The EpiOcular™ Eye Irritation Test is the Method of Choice for the In Vitro Eye Irritation Testing of Agrochemical Formulations: Correlation Analysis of EpiOcular Eye Irritation Test and BCOP Test Data According to the UN GHS, US EPA and Brazil ANVI

scientific article

The stability of historical control data for common neoplasms in laboratory rats and the implications for carcinogenic risk assessment

scientific article

The stability of historical control data for common neoplasms in laboratory rats: adrenal gland (medulla), mammary gland, liver, endocrine pancreas, and pituitary gland

scientific article

Time course of lung retention and toxicity of inhaled particles: short-term exposure to nano-Ceria

scientific article

Toward a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - part I: which parameters from human studies are most relevant for toxicological assessments?

scientific article published on 11 December 2020

Towards a generic physiologically based kinetic model to predict in vivo uterotrophic responses in rats by reverse dosimetry of in vitro estrogenicity data

scientific article published on 12 December 2017

Use of physiologically based kinetic modeling-facilitated reverse dosimetry of in vitro toxicity data for prediction of in vivo developmental toxicity of tebuconazole in rats

scientific article

Use of the ES-D3 cell differentiation assay, combined with the BeWo transport model, to predict relative in vivo developmental toxicity of antifungal compounds

scientific article

Uterine adenocarcinoma in the rat induced by afidopyropen. An analysis of the lesion's induction, progression and its relevance to humans

scientific article published on 3 March 2018

Vinclozolin--no transgenerational inheritance of anti-androgenic effects after maternal exposure during organogenesis via the intraperitoneal route

scientific article

Vinclozolin--the lack of a transgenerational effect after oral maternal exposure during organogenesis

scientific article published on 9 April 2008

Vinclozolin: A case study on the identification of endocrine active substances in the past and a future perspective ⬇️

scientific article published on December 16, 2013

Vinclozolin: A feasibility and sensitivity study of the ILSI-HESI F1-extended one-generation rat reproduction protocol ⬇️

scientific article published on September 25, 2010

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