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List of works by Jörg Felsberg

5-ALA-induced fluorescence behavior of reactive tissue changes following glioblastoma treatment with radiation and chemotherapy

scientific article published on 30 December 2014

5-Aminolevulinic acid (5-ALA)-induced fluorescence in intracerebral metastases: a retrospective study ⬇️

scientific article published on November 12, 2011

ACTR-05. THE RANDOMIZED PHASE II ARTE TRIAL: BEVACIZUMAB PLUS HYPOFRACTIONATED RADIOTHERAPY VERSUS RADIOTHERAPY ALONE IN ELDERLY PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA.

scientific article published on 6 November 2017

Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas

scientific article

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification

scientific article published on 17 May 2010

Analysing DNA methylation using bisulphite pyrosequencing.

scientific article

Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker

scientific article published on 8 April 2008

Association of Stem Cell-Related Markers and Survival in Astrocytic Gliomas ⬇️

scientific article published on March 1, 2011

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.

scientific article published on 23 June 2013

CASP9 germline mutation in a family with multiple brain tumors

scientific article

Case report: extracranial metastasis from gliosarcoma – the influence of immune system ⬇️

scientific article published on December 15, 2010

Cerebellar Hemorrhage in Extremely Low Birth Weight Siblings: Is There a Familial Disposition? ⬇️

scientific article published on February 10, 2011

Chemotherapy for intracranial ependymoma in adults

scientific article

Comparison of (18)F-FET PET and 5-ALA fluorescence in cerebral gliomas

scientific article published on 10 December 2010

Cordectomy as final treatment option for diffuse intramedullary malignant glioma using 5-ALA fluorescence-guided resection

scientific article published on 12 January 2010

Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

scientific article published in Nature

DNA hypermethylation and aberrant expression of the EMP3 gene at 19q13.3 in Human Gliomas

scientific article

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

scientific article

Diagnostic performance of 18F-FET PET in newly diagnosed cerebral lesions suggestive of glioma

scientific article published on 11 December 2012

Differential retinoic acid signaling in tumors of long- and short-term glioblastoma survivors

scientific article published on 23 February 2011

Dissecting the genomic complexity underlying medulloblastoma

scientific article

Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma

scientific article published in August 2007

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

scientific article

Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells

scientific article

Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer

scientific article

Erratum to: Gliomatosis cerebri: no evidence for a separate brain tumor entity

scientific article published on 7 January 2016

Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas ⬇️

scientific article published on December 10, 2010

Finding the anaplastic focus in diffuse gliomas: the value of Gd-DTPA enhanced MRI, FET-PET, and intraoperative, ALA-derived tissue fluorescence

scientific article published on 20 April 2011

Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas

scientific article

Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors.

scientific article

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

scientific article

Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival

scientific article published on 27 October 2009

Giant cell glioblastoma is associated with altered aurora b expression and concomitant p53 mutation

scientific article

Gliomatosis cerebri: molecular pathology and clinical course

scientific article published in October 2002

Gliomatosis cerebri: no evidence for a separate brain tumor entity

scientific article published on 22 October 2015

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

scientific article published in October 2012

Identification of genomic aberrations associated with shorter overall survival in patients with oligodendroglial tumors

scientific article published in June 2007

Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro.

scientific article published on 27 April 2018

Is it a glioblastoma? In dubio pro 5-ALA! ⬇️

scientific article published on May 11, 2012

LGG-10. PROTEOGENOMICS DISCRIMINATES PEDIATRIC AND ADULT PILOCYTIC ASTROCYTOMA AS DISTINCT BIOLOGICAL ENTITIES.

scientific article published on 31 May 2017

Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma

scientific article

MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial

scientific article published on 5 February 2015

Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective

scientific article published on 17 April 2013

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups

scientific article published on 28 January 2016

MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation

scientific article published on 04 December 2013

Molecular Diagnostics of Gliomas Using Next Generation Sequencing of a Glioma-Tailored Gene Panel

scientific article

Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling.

scientific article

Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups

scientific article published on 18 March 2015

Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network

scientific article published on 5 October 2009

Molecular signatures classify astrocytic gliomas by IDH1 mutation status.

scientific article published in March 2011

NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide

scientific article published on 9 November 2009

NOA-05 phase 2 trial of procarbazine and lomustine therapy in gliomatosis cerebri

scientific article published on 27 June 2011

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

scientific article

Oligodendroglial tumors: refinement of candidate regions on chromosome arm 1p and correlation of 1p/19q status with survival.

scientific article

Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis

scientific article published on July 2007

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

scientific article (publication date: April 2009)

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas

scientific article

Potential CanonicalWntPathway Activation in High-Grade Astrocytomas ⬇️

scientific article published on August 2, 2012

Predictive impact of MGMT promoter methylation in glioblastoma of the elderly

scientific article published on 11 January 2012

Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort

scientific article

Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients

scientific article published on 27 October 2009

Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.

scientific article

Proof of principle: supramarginal resection of cerebral metastases in eloquent brain areas ⬇️

scientific article published on August 9, 2012

Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery ⬇️

scientific article published on February 4, 2012

RANK (TNFRSF11A) Is Epigenetically Inactivated and Induces Apoptosis in Gliomas ⬇️

scientific article published on June 1, 2012

Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing

scientific article published on 4 February 2010

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

scientific article

Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma

scientific article

Sellar Region Atypical Teratoid/Rhabdoid Tumors (ATRT) in Adults Display DNA Methylation Profiles of the ATRT-MYC Subgroup

scientific article published on 10 January 2018

Septic-Metastasizing Aspergillus-Encephalitis Mimicking Massive Cerebral Infarction in a Heart Transplant Recipient: A Case Report

scientific article

TRTH-28. HIGH THROUGHPUT SCREENING OF NOVEL HISTONE DEACETYLASE INHIBITORS FOR EPIGENETIC THERAPY OF PRIMARY BRAIN TUMORS.

scientific article

Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial

scientific article

The transcription factor evi-1 is overexpressed, promotes proliferation, and is prognostically unfavorable in infratentorial ependymomas

scientific article

Troglitazone-mediated sensitization to TRAIL-induced apoptosis is regulated by proteasome-dependent degradation of FLIP and ERK1/2-dependent phosphorylation of BAD.

scientific article

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

scientific article published on 25 June 2009

Whole-genome paired-end analysis confirms remarkable genomic stability of atypical teratoid/rhabdoid tumors.

scientific article published on 9 August 2013

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