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List of works by James U. Bowie

A C alpha-H...O hydrogen bond in a membrane protein is not stabilizing

scientific article

A Novel Cytoplasmic Tail MXXXL Motif Mediates the Internalization of Prostate-specific Membrane Antigen ⬇️

scientific article published on October 3, 2003

A bio-inspired cell-free system for cannabinoid production from inexpensive inputs

scientific article published on 24 August 2020

A cell-free platform for the prenylation of natural products and application to cannabinoid production

scientific article published in Nature Communications

A human sterile alpha motif domain polymerizome

scientific article

A limited universe of membrane protein families and folds

scientific article

A model of the closed form of the nicotinic acetylcholine receptor m2 channel pore

scientific article

A molecular rheostat maintains ATP levels to drive a synthetic biochemistry system.

scientific article published on 3 July 2017

A role for zinc in postsynaptic density asSAMbly and plasticity?

scientific article published on 21 June 2006

A simple DNA handle attachment method for single molecule mechanical manipulation experiments

scientific article

A simple method for modeling transmembrane helix oligomers

scientific article published in June 2003

A synthetic biochemistry module for production of bio-based chemicals from glucose.

scientific article published on 11 April 2016

A synthetic biochemistry molecular purge valve module that maintains redox balance

scientific article published on 17 June 2014

A synthetic biochemistry platform for cell free production of monoterpenes from glucose

scientific article published on 24 May 2017

A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates

scientific article published on 12 March 2014

A transmembrane segment mimic derived from Escherichia coli diacylglycerol kinase inhibits protein activity

scientific article published on 9 April 2003

Accurate computational design of multipass transmembrane proteins.

scientific article published in March 2018

An Adaptation To Life In Acid Through A Novel Mevalonate Pathway.

scientific article published on 22 December 2016

An architectural framework that may lie at the core of the postsynaptic density

scientific article

An energetic scale for equilibrium H/D fractionation factors illuminates hydrogen bond free energies in proteins.

scientific article

Analysis of side-chain rotamers in transmembrane proteins

scientific article

Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response

scientific article published on 18 July 2005

Applications of Single-Molecule Methods to Membrane Protein Folding Studies

scientific article

Asymmetric amino acid compositions of transmembrane beta-strands

scientific article

Author Correction: A cell-free platform for the prenylation of natural products and application to cannabinoid production

scholarly article published in Nature Communications

Backbone Hydrogen Bond Strengths Can Vary Widely in Transmembrane Helices.

scientific article published on 10 July 2017

Bacteriorhodopsin folds through a poorly organized transition state

scientific article published on 17 November 2014

Bicelle crystallization: a new method for crystallizing membrane proteins yields a monomeric bacteriorhodopsin structure

scientific article

Cell biology: border crossing

scientific article published on 01 January 2005

Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3

scientific article

Complete topology inversion can be part of normal membrane protein biogenesis

scientific article published on 7 February 2017

Construction of helix-bundle membrane proteins

scientific article

Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6.

scientific article published on 26 December 2017

Crystal Structure of Proteus mirabilis Lipase, a Novel Lipase from the Proteus/Psychrophilic Subfamily of Lipase Family I.1

scientific article

Crystal Structure of the Central Coiled-Coil Domain from Human Liprin-β2

scientific article

Crystallization of bacteriorhodopsin from bicelle formulations at room temperature

scientific article published on 2 February 2005

Crystallizing membrane proteins using lipidic bicelles

scientific article published on 29 September 2011

Derepression by depolymerization; structural insights into the regulation of Yan by Mae.

scientific article published on July 2004

Dieselzymes: development of a stable and methanol tolerant lipase for biodiesel production by directed evolution

scientific article

Dimerization of the transmembrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants

scientific article

Dramatic destabilization of transmembrane helix interactions by features of natural membrane environments

scientific article published on 5 July 2011

Dual-topology insertion of a dual-topology membrane protein

scientific article published on 26 August 2015

Evaluation of C-H cdots, three dots, centered O hydrogen bonds in native and misfolded proteins

scientific article published in September 2002

Evidence of a novel mevalonate pathway in archaea

scientific article published on 18 June 2014

Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice

scientific article

Flip-flopping membrane proteins

scientific article published on 01 February 2006

G-protein-coupled receptor structures were not built in a day

scientific article

Genetic selection system for improving recombinant membrane protein expression in E. coli

scientific article published in February 2009

HotPatch: a statistical approach to finding biologically relevant features on protein surfaces

scientific article published on 21 March 2007

How Bilayer Properties Influence Membrane Protein Folding

scientific article published on 15 October 2020

How to prepare membrane proteins for solid-state NMR: A case study on the alpha-helical integral membrane protein diacylglycerol kinase from E. coli.

scientific article

Identifying polymer-forming SAM domains

scientific article published on January 2009

Improving the tolerance of Escherichia coli to medium-chain fatty acid production

scientific article published on 13 June 2014

Isobutanol production freed from biological limits using synthetic biochemistry

scientific article published on 27 August 2020

Janus model of the Na,K-ATPase beta-subunit transmembrane domain: distinct faces mediate alpha/beta assembly and beta-beta homo-oligomerization

scientific article published on 31 October 2006

Mae inhibits Pointed-P2 transcriptional activity by blocking its MAPK docking site.

scientific article published on 15 December 2005

Mapping the energy landscape for second-stage folding of a single membrane protein

scientific article published on 19 October 2015

Measuring membrane protein stability under native conditions

scientific article published on 23 December 2013

Measuring transmembrane helix interaction strengths in lipid bilayers using steric trapping.

scientific article

Membrane channel structure of Helicobacter pylori vacuolating toxin: role of multiple GXXXG motifs in cylindrical channels.

scholarly article

Membrane protein folding: how important are hydrogen bonds? ⬇️

scientific article published on November 12, 2010

Membrane proteins can have high kinetic stability

scientific article published on 27 September 2013

Membrane proteins: a new method enters the fold

scholarly article

Metazoans evolved by taking domains from soluble proteins to expand intercellular communication network

scientific article published on 29 April 2015

Method to measure strong protein-protein interactions in lipid bilayers using a steric trap

scientific article

Methods for measuring the thermodynamic stability of membrane proteins.

scientific article

Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins

scientific article

Molecular dynamics simulation strategies for protein-micelle complexes.

scientific article

Native interface of the SAM domain polymer of TEL.

scientific article

Network rewiring is an important mechanism of gene essentiality change

scientific article

Oligomerization-dependent association of the SAM domains from Schizosaccharomyces pombe Byr2 and Ste4.

scientific article published on 8 August 2002

Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel.

scientific article published on 23 January 2005

Point mutations in membrane proteins reshape energy landscape and populate different unfolding pathways

scientific article published on 23 December 2007

Polymer-driven crystallization

scientific article

Post-translational modifications of integral membrane proteins resolved by top-down Fourier transform mass spectrometry with collisionally activated dissociation

scientific article

Probing membrane protein unfolding with pulse proteolysis.

scientific article

Production of FAME biodiesel in E. coli by direct methylation with an insect enzyme

scientific article

Proline substitutions are not easily accommodated in a membrane protein

scientific article

Protein unfolding with a steric trap

scientific article

Rampant exchange of the structure and function of extramembrane domains between membrane and water soluble proteins

scientific article

Regulation of clathrin adaptor function in endocytosis: novel role for the SAM domain

scientific article

Regulation of enzyme localization by polymerization: polymer formation by the SAM domain of diacylglycerol kinase delta1

scientific article

Revisiting the folding kinetics of bacteriorhodopsin.

scientific article published on 5 December 2011

SAM domains can utilize similar surfaces for the formation of polymers and closed oligomers

scientific article

SAM domains: uniform structure, diversity of function

scientific article (publication date: December 2003)

Secondary structure and backbone dynamics of Escherichia coli diacylglycerol kinase, as revealed by site-directed solid-state 13C NMR.

scientific article published in April 2004

Shifting hydrogen bonds may produce flexible transmembrane helices.

scientific article

Side-chain contributions to membrane protein structure and stability

scientific article

Similar Energetic Contributions of Packing in the Core of Membrane and Water-Soluble Proteins

scientific article

Single-Molecule Measurement of Membrane Protein Stability

Snorkeling preferences foster an amino acid composition bias in transmembrane helices

scientific article

Solving the membrane protein folding problem

scientific article

Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases

scientific article

Structural biology. Membrane protein twists and turns.

scientific article

Structural differences between thermophilic and mesophilic membrane proteins

scientific article published on November 2012

Structural imperatives impose diverse evolutionary constraints on helical membrane proteins

scientific article

Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer

scientific article

Synthetic Biochemistry: The Bio-inspired Cell-Free Approach to Commodity Chemical Production

scientific article published on 23 January 2020

TMKink: A method to predict transmembrane helix kinks ⬇️

scientific article published on June 2, 2011

Tandem SAM Domain Structure of Human Caskin1: A Presynaptic, Self-Assembling Scaffold for CASK

scientific article

The Affinity of GXXXG Motifs in Transmembrane Helix-Helix Interactions Is Modulated by Long-range Communication

scientific article published in Journal of Biological Chemistry

The Database of Interacting Proteins: 2004 update

scientific article (publication date: 2004)

The Molecular Basis of the Caskin1 and Mint1 Interaction with CASK ⬇️

scientific article published on July 12, 2011

The SAM domain of polyhomeotic forms a helical polymer

scientific article

The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors

scientific article

The grand unifying theory of bright echoes in the fetal and neonatal brain

scientific article published in October 2012

The many faces of SAM

scientific article

Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state.

scientific article

Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state

scientific article published on 10 December 2004

Transmembrane domain of myelin protein zero can form dimers: possible implications for myelin construction

scientific article

Transmembrane glycine zippers: physiological and pathological roles in membrane proteins

scientific article

Unfolding of a ClC chloride transporter retains memory of its evolutionary history

scientific article published on 26 March 2018

Watching helical membrane proteins fold reveals a common N-to-C-terminal folding pathway

scientific article

Zinc Binding Drives Sheet Formation by the SAM Domain of Diacylglycerol Kinase δ ⬇️

scientific article published on November 9, 2010

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