List of works by Kristian Pietras

A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition

scientific article published on 13 July 2009

A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer.

scientific article published on 22 November 2004

Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML.

scientific article published on 21 March 2016

Activin receptor-like kinase 1 is associated with immune cell infiltration and regulates CLEC14A transcription in cancer.

scientific article published on 21 August 2018

Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression.

scientific article published on 16 October 2013

Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling

scientific article published on 28 November 2018

Cartilage oligomeric matrix protein contributes to the development and metastasis of breast cancer.

scientific article published on 11 April 2016

Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

scientific article published on 18 October 2016

Compound genetically engineered mouse models of cancer reveal dual targeting of ALK1 and endoglin as a synergistic opportunity to impinge on angiogenic TGF-β signaling.

scientific article published on 12 October 2016

Consensus guidelines for the use and interpretation of angiogenesis assays

article

DNA promoter hypermethylation of melanocyte lineage genes determines melanoma phenotype

scientific article published in 2022

Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination

scientific article published on 11 February 2013

Distinct effects of ligand-induced PDGFRα and PDGFRβ signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartments.

scientific article published on 21 January 2013

Editorial: Novel Targets and Targeting Technologies to Modulate Tumor Microenvironment.

scientific article published on 17 May 2016

Effect of platelet-derived growth factor receptor-beta inhibition with STI571 on radioimmunotherapy.

scientific article

Endothelial ALK1 Is a Therapeutic Target to Block Metastatic Dissemination of Breast Cancer.

scientific article published on June 2015

Engineered high-affinity affibody molecules targeting platelet-derived growth factor receptor β in vivo.

scientific article

Expression of GADS enhances FLT3-induced mitogenic signaling.

scientific article published in March 2016

Fibroblasts as architects of cancer pathogenesis

scientific article published on 30 October 2012

Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD

scientific article published on February 2016

Functional subsets of mesenchymal cell types in the tumor microenvironment

scientific article published on 07 January 2014

Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting

scientific article (publication date: 29 January 2008)

Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis. ⬇️

scientific article

Hallmarks of cancer: interactions with the tumor stroma.

scientific article published on 06 March 2010

Heterogeneity of cancer-associated fibroblasts: Opportunities for precision medicine

scientific article published on 23 June 2020

High interstitial fluid pressure - an obstacle in cancer therapy

scientific article (publication date: October 2004)

Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ

scientific article published on 01 September 2019

Increasing tumor uptake of anticancer drugs with imatinib.

scientific article published on April 2004

Introduction to tumor-stroma interactions

scientific article published on 25 June 2013

MNK2 governs the macrophage antiinflammatory phenotype

scientific article published on 19 October 2020

Mast cells are novel independent prognostic markers in prostate cancer and represent a target for therapy

scientific article published on 8 July 2010

Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling.

scientific article published on 12 March 2018

Molecular biology of neuroendocrine tumors: from pathways to biomarkers and targets

scientific article published on March 2014

Noninvasive intravital high-resolution imaging of pancreatic neuroendocrine tumours

scientific article published on 10 October 2019

Novel nano-sized MR contrast agent mediates strong tumor contrast enhancement in an oncogene-driven breast cancer model

scientific article

Of mice and men: a comparative study of cancer-associated fibroblasts in mammary carcinoma.

scientific article published on 21 March 2012

On the origin of cancer-associated fibroblasts

scientific article published on 25 May 2009

PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer

scientific article published on 09 August 2019

PDGF family function and prognostic value in tumor biology

scientific article published on 23 June 2018

Pericytes contribute to airway remodeling in a mouse model of chronic allergic asthma

scientific article

Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression

scientific article

Platelet-derived growth factor D induces cardiac fibrosis and proliferation of vascular smooth muscle cells in heart-specific transgenic mice

scientific article published on 13 October 2005

Protein detection using proximity-dependent DNA ligation assays.

scientific article

Recruited fibroblasts reconstitute the peri-islet membrane: a longitudinal imaging study of human islet grafting and revascularisation

scientific article published on 07 November 2019

Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease

scientific article published on 08 May 2019

STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake ⬇️

scientific article published on September 1, 2003

Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

scientific article published in Nature Communications

Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer

scientific article published on 26 May 2016

Targeting tumour vasculature by inhibiting activin receptor-like kinase (ALK)1 function.

scientific article published on August 2016

The PDGF pathway in breast cancer is linked to tumour aggressiveness, triple-negative subtype and early recurrence.

scientific article

The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma

scientific article published on 01 June 2019

Therapeutic efficacy of a DNA vaccine targeting the endothelial tip cell antigen delta-like ligand 4 in mammary carcinoma

scientific article published on 24 May 2010

Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma

scientific article published on 01 September 2020

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer

scientific article

Upregulated functional gene expression programmes in tumour pericytes mark progression in patients with low-grade glioma

scientific article published on 05 June 2021

Vascular endothelial growth factor B controls endothelial fatty acid uptake.

scientific article published on 14 March 2010

Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I.

scientific article

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