List of works by Olle Korsgren

15-Deoxyspergualin prolongs pancreatic islet allo- and xenograft survival in mice

scientific article published on 01 July 1993

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004 ⬇️

article

A comparison of fetal and adult porcine islets with regard to Gal alpha (1,3)Gal expression and the role of human immunoglobulins and complement in islet cell cytotoxicity

scientific article published on April 2000

A new in vitro model for the study of pig-to-human vascular hyperacute rejection

scientific article published on 01 August 2001

A new method for incorporating functional heparin onto the surface of islets of Langerhans

scientific article

A new murine model of islet xenograft rejection: graft destruction is dependent on a major histocompatibility-specific interaction between T-cells and macrophages.

scientific article

A new oxygen carrier for improved long-term storage of human pancreata before islet isolation

scientific article

A novel model for studies of blood-mediated long-term responses to cellular transplants

scientific article

A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets

scientific article

Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation

scientific article published on April 2008

Adenovirus CD40 ligand gene therapy counteracts immune escape mechanisms in the tumor Microenvironment

scientific article published in June 2004

Adenovirus serotype 5 vectors with Tat-PTD modified hexon and serotype 35 fiber show greatly enhanced transduction capacity of primary cell cultures

scientific article

Adenovirus-mediated expression of human CD55 or CD59 protects adult porcine islets from complement-mediated cell lysis by human serum

scientific article published in March 2003

Adenovirus-mediated expression of the anticoagulant hirudin in human islets: a tool to make the islets biocompatible to blood

scientific article published in January 2006

Aetiology of type 1 diabetes: Physiological growth in children affects disease progression

scientific article

Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice

scientific article published on March 1997

An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets

scientific article published on 21 December 2016

Anakinra and tocilizumab enhance survival and function of human islets during culture: implications for clinical islet transplantation

scientific article published on 29 April 2013

Anchoring of vascular endothelial growth factor to surface-immobilized heparin on pancreatic islets: implications for stimulating islet angiogenesis

scientific article

Angiogenesis and angioarchitecture of transplanted fetal porcine islet-like cell clusters

scientific article published on 01 December 1999

Antisense NF-kappaB p65 prolongs experimental allo- and xenograft survival

scientific article published on 01 February 2001

Antiviral effect of nicotinamide on enterovirus-infected human islets in vitro: effect on virus replication and chemokine secretion

scientific article published on June 2009

Antiviral treatment of Coxsackie B virus infection in human pancreatic islets

scientific article

Aspects of pancreatic islet transplantation in diabetes mellitus

scientific article published on October 1989

Blood vessels of human islets of Langerhans are surrounded by a double basement membrane

scientific article published on 26 April 2008

Brequinar in combination with cyclosporine a inhibits islet xenograft rejection for up to 24 days: a study in the pig-to-rat model

scientific article published on 01 August 2000

C-Peptide determinations in islet xenotransplantation: A study in the pig-to-mouse model

scientific article published on 01 March 2001

Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?

scientific article

Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs

scientific article published on 16 April 2016

Characterization of Innate Immunity in an Extended Whole Blood Model of Human Islet Allotransplantation.

scientific article

Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture

scientific article published in August 2003

Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies

scientific article published on 27 August 2015

Characterization of mixed syngeneic-allogeneic and syngeneic-xenogeneic islet-graft rejections in mice. Evidence of functional impairment of the remaining syngeneic islets in xenograft rejections

scientific article

Characterization of natural and induced human xenophile antibodies before and after transplantation of the fetal porcine endocrine pancreas

scientific article published on 01 June 1994

Clinical and experimental pancreatic islet transplantation to striated muscle: establishment of a vascular system similar to that in native islets

scientific article published on 22 July 2010

Clinical aspects and perspectives in islet xenotransplantation

scientific article

Clostripain, the Missing Link in the Enzyme Blend for Efficient Human Islet Isolation

scientific article published on 24 June 2015

Co-stimulatory molecules in islet xenotransplantation: CTLA4Ig treatment in CD40 ligand-deficient mice

article

Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345.

scientific article published in September 2017

Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation.

scientific article

Comparison of Neutral Proteases and Collagenase Class I as Essential Enzymes for Human Islet Isolation

scientific article published on 15 December 2015

Complement regulatory proteins on human and porcine nontransgenic and hDAF transgenic islet cells: expression and role in susceptibility to lysis by human serum

scientific article published on 01 August 2000

Composite islet-endothelial cell grafts: a novel approach to counteract innate immunity in islet transplantation.

scientific article published in November 2005

Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftment

scientific article published on December 2011

Cost and clinical outcome of islet transplantation in Norway 2010-2015.

scientific article

Current advances and travails in islet transplantation

scientific article published on October 2009

Current status of clinical islet transplantation

scientific article

Cyclosporine induces long-term xenograft survival in the mouse-to-C6-deficient rat heart transplantation model

scientific article published on 01 August 2000

DNA replication in mouse pancreatic islets transplanted subcapsularly into the kidney or intraportally into the liver. Influence of unilateral nephrectomy or partial hepatectomy

scientific article published on 01 April 1990

DNA replication in pancreatic islets and adrenals in diabetic Chinese hamsters

scientific article published on 01 January 1993

DNA replication in transplanted and endogenous pancreatic islets of obese-hyperglycemic mice at different stages of the syndrome

scientific article published on 01 October 1989

Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin

scientific article published on 01 March 2000

Decreased defluorination using the novel beta-cell imaging agent [18F]FE-DTBZ-d4 in pigs examined by PET

scientific article published on 5 December 2011

Decreased proportion of cytomegalovirus specific CD8 T-cells but no signs of general immunosenescence in Alzheimer's disease

scientific article

Delayed type hypersensitivity-associated cytokines in islet xenotransplantation: limited efficacy of interleukin-2- and tumor necrosis factor-alpha-blockade in interferon-gamma receptor-deficient mice.

scientific article published in August 2000

Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes

scientific article

Deoxyspergualin delays xenograft rejection in the guinea pig-to-C6-deficient rat heart transplantation model

scientific article published on 01 January 1999

Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer

Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes

scientific article

Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry?

scientific article published on 19 December 2013

Detection of metastatic insulinoma by positron emission tomography with [(68)ga]exendin-4-a case report

scientific article

Diabetic rats transplanted with adult porcine islets and immunosuppressed with cyclosporine A, mycophenolate mofetil, and leflunomide remain normoglycemic for up to 100 days

scientific article published in April 2001

Diabetic rats transplanted with adult porcine islets and immunosuppressed with cyclosporine, mycophenolate mofetil, and leflunomide remain normoglycemic for up to 100 days

scientific article published on 01 August 2000

Differentiation and maturation of porcine fetal islet cells in vitro and after transplantation

scientific article published on 01 December 1999

Direct Substrate Delivery Into Mitochondrial Fission-Deficient Pancreatic Islets Rescues Insulin Secretion

scientific article published on 7 February 2017

Discordant cellular xenografts revascularized in intermediate athymic hosts fail to induce a hyperacute rejection when transplanted to immunocompetent rats

scientific article published on 01 May 1994

Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation

scientific article published in July 2008

Distribution of adoptively transferred porcine T-lymphoblasts tracked by (18)F-2-fluoro-2-deoxy-D-glucose and position emission tomography

scientific article published on 21 April 2011

Distribution of the Galalpha1-3Gal antigen in cultured adult and fetal porcine pancreatic islet cells: an immunoelectron microscopic study

scientific article published on 01 September 2000

Effect of plasma exchange in combination with deoxyspergualin on the survival of guinea-pig hearts in macrophage-depleted C6-deficient rats

scientific article published in May 2003

Effects of culture conditions on formation and hormone content of fetal porcine isletlike cell clusters

scientific article published on 01 January 1989

Effects of cyclosporin A on the blood flow of the native and transplanted rat pancreas and duodenum

scientific article published on 01 May 1993

Effects of hyperglycemia on function of isolated mouse pancreatic islets transplanted under kidney capsule

scientific article published on 01 April 1989

Effects of immunosuppressive drugs on in vitro neogenesis of human islets: mycophenolate mofetil inhibits the proliferation of ductal cells.

scientific article published in April 2007

Effects of streptozotocin-induced diabetes in domestic pigs with focus on the amino acid metabolism

scientific article published on 26 February 2009

Efficacy of immunosuppressive drugs in islet xenotransplantation: leflunomide in combination with cyclosporine and mycophenolate mofetil prevents islet xenograft rejection in the pig-to-rat model

scientific article published on 01 May 1997

Efficacy of malononitriloamide 279 and 715 in islet xenotransplantation: a study in the pig-to-rat model

scientific article published on 01 August 2000

Efficacy of various immunosuppressive drugs in preventing pig-to-rat islet xenograft rejection.

scientific article

Efficient adenovector CD40 ligand immunotherapy of canine malignant melanoma

scientific article published in May 2008

Endovascular method for transplantation of insulin-producing cells to the pancreas parenchyma in swine

scientific article published on 12 February 2014

Engraftment of isolated islets after syngeneic transplantation into normal and diabetic mice

scientific article published in June 1992

Enhanced survival of porcine neural xenografts in mice lacking CD1d1, but no effect of NK1.1 depletion

scientific article published in January 2001

Enterovirus-induced gene expression profile is critical for human pancreatic islet destruction

article

Enteroviruses and the pathogenesis of type 1 diabetes revisited: cross-reactivity of enterovirus capsid protein (VP1) antibodies with human mitochondrial proteins

scientific article published in April 2013

Erratum. Direct Substrate Delivery Into Mitochondrial Fission-Deficient Pancreatic Islets Rescues Insulin Secretion. Diabetes 2017;66:1247-1257.

scientific article published on 12 October 2017

Erratum. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418-3428.

scientific article published on 29 June 2017

Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation

scientific article

Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans

scientific article

Evidence of xenograft function in a diabetic patient grafted with porcine fetal pancreas.

scientific article published in June 1992

Ex vivo propagation and characterization of lymphocytes from rejecting rat-kidney allografts

scientific article published on 01 December 1999

Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of β-Cell Replacement

scientific article published on 14 April 2016

Experience with 450 adult porcine islet isolation procedures

scientific article published in June 2001

Experience with human islet transplantation in Sweden

scientific article published in June 2001

Experimental and clinical experience with xenoislet transplantation

scientific article published on 01 December 1996

Experimental pancreatic transplantation in diabetes

scientific article published on November 1988

Experimental studies of transplantation and regeneration of endocrine pancreatic cells

scientific article published on 01 January 1985

Expression of complement regulatory proteins on islets of Langerhans: a comparison between human islets and islets isolated from normal and hDAF transgenic pigs

scientific article

Expression of islet amyloid polypeptide in fetal and adult porcine and human pancreatic islet cells

scientific article published on 01 December 1996

Expression of islet amyloid polypeptide in fetal and adult porcine and human pancreatic islet cells

scientific article published on 01 April 1997

Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism

scientific article published on 15 February 2018

FK 506 prevents islet xenograft rejection: a study in the pig-to-rat model

scientific article published on 01 February 1999

FTY720 in combination with CsA inhibits islet xenograft rejection: a study in the pig-to-rat model

scientific article published on 01 August 2000

Factors impeding the discovery of an intervention-based treatment for type 1 diabetes

scientific article published on 19 May 2015

First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 4: pre-clinical efficacy and complication data required to just

scientific article

Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization

scientific article published on 2 June 2008

Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study

scientific article published on 12 February 2015

Functional and morphological differentiation of fetal porcine islet-like cell clusters after transplantation into nude mice

scientific article published in June 1991

Functional characteristics of cultured mouse pancreatic islets following exposure to different streptozotocin concentrations

scientific article published on 01 September 1988

Functional maturation of fetal porcine isletlike cell clusters after transplantation into nude mice

scientific article published on 01 April 1990

Further evidence for amyloid deposition in clinical pancreatic islet grafts

scientific article

GPR44 is a pancreatic protein restricted to the human beta cell

scientific article published on 14 October 2015

Gene expression analysis of human islets in a subject at onset of type 1 diabetes

scientific article

Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis

scientific article

Glucocorticoids reduce pro-inflammatory cytokines and tissue factor in vitro and improve function of transplanted human islets in vivo

scientific article

Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo

scientific article

Human islet separation utilizing a closed automated purification system.

scientific article published in January 2008

Human pancreatic islet preparations release HMGB1: (ir)relevance for graft engraftment

scientific article published on 8 October 2012

Hyperglycemia-induced B cell toxicity. The fate of pancreatic islets transplanted into diabetic mice is dependent on their genetic background

scientific article published in December 1990

Identification of proliferative and mature β-cells in the islets of Langerhans.

scientific article published on 11 July 2016

Imaging the in vivo fate of human T cells following transplantation in immunoincompetent mice - implications for clinical cell therapy trials

scientific article published on 29 September 2013

Imagining a better future for all people with type 1 diabetes mellitus

scientific article published on 01 November 2019

Immune response of diabetic patients against transplanted porcine fetal islet cells

scientific article published on 01 April 1992

Immunogenicity of Hanganutziu-Deicher antigens in pig-to-human xenotransplantation

scientific article published on 01 August 2000

Immunological characteristics of islet cell xenotransplantation in humans and rodents

scientific article published on October 1994

Immunosuppression with FTY720 and cyclosporine A inhibits rejection of adult porcine islet xenografts in rats

scientific article published in April 2003

Immunosuppression with cyclosporin A in combination with leflunomide and mycophenolate mofetil prevents rejection of pig-islets transplanted into rats

scientific article published on 01 April 1996

Immunosuppression with leflunomide and cyclosporine prevents pig-to-rat islet xenograft rejection

scientific article published on 01 December 1995

Immunosuppressive drugs in islet xenotransplantation: a tool for gaining further insights in the mechanisms of the rejection process

scientific article published in October 2002

Importance of the Gal alpha1-3 Gal antigen in discordant islet xenotransplantation: immunosuppression, which inhibits porcine islet xenograft rejection in ordinary mice, is equally effective in Gal-knockout mice

scientific article

Improving islet transplantation: a road map for a widespread application for the cure of persons with type I diabetes

scientific article published on December 2009

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome

scholarly article published in Stem Cells Translational Medicine

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome.

scientific article

In Vivo Visualization of Beta Cells by Targeting of GPR44.

scientific article published on 5 December 2017

In vitro neogenesis of human islets reflects the plasticity of differentiated human pancreatic cells

scientific article

In vitro screening of putative compounds inducing fetal porcine pancreatic beta-cell differentiation: implications for cell transplantation in insulin-dependent diabetes mellitus

scientific article

In vivo and in vitro characterization of [18F]-FE-(+)-DTBZ as a tracer for beta-cell mass

scientific article published on 15 January 2010

In vivo imaging of the glucagonlike peptide 1 receptor in the pancreas with 68Ga-labeled DO3A-exendin-4.

scientific article published on 12 June 2013

Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation?

scientific article published in October 1999

Increased inflammatory response in cytomegalovirus seropositive patients with Alzheimer's disease

scientific article

Induction of an antiviral state and attenuated coxsackievirus replication in type III interferon-treated primary human pancreatic islets

scientific article published on May 2013

Induction of the chemokine interferon-gamma-inducible protein-10 in human pancreatic islets during enterovirus infection

scientific article published on 13 September 2006

Infection of human islets of Langerhans with two strains of Coxsackie B virus serotype 1: assessment of virus replication, degree of cell death and induction of genes involved in the innate immunity pathway

scientific article published on 19 November 2013

Inflammatory mediators expressed in human islets of Langerhans: implications for islet transplantation

scientific article (publication date: 29 August 2003)

Influence of persistent hyperglycemia on transplanted pancreatic islets.

scientific article published on January 1990

Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation

scientific article published in June 2002

Injection of xenogeneic endocrine pancreatic tissue into the portal vein--effects on coagulation, liver function, and hepatic hemodynamics. A study in the pig-to-dog model

scientific article published on 01 January 1992

Insulin independence after conversion from tacrolimus to cyclosporine in islet transplantation

scientific article

Insulin-heparin infusions peritransplant substantially improve single-donor clinical islet transplant success

scientific article published in February 2010

Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

scientific article published on 24 November 2015

Insulitis in human diabetes: a histological evaluation of donor pancreases

scientific article published on 28 October 2016

Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT.

scientific article published on 12 January 2018

Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets in vitro.

scientific article published on 23 June 2015

Intracerebral cytokine profiles in adult rats grafted with neural tissue of different immunological disparity

scientific article published in March 2004

Intragraft cytokine mRNA expression in rejecting and non-rejecting vascularized xenografts

scientific article

Intraportal pig islet xenotransplantation into athymic mice as an in vivo model for the study of the instant blood-mediated inflammatory reaction

scientific article published in March 2004

Intraportally transplanted pancreatic islets revascularized from hepatic arterial system

scientific article published in January 1989

Islet Encapsulation: Physiological Possibilities and Limitations

scientific article published in July 2017

Islet Gene View - a tool to facilitate islet research

article

Islet Transplantation & β-Cell Replacement Therapies for Diabetes

scientific article published on January 2011

Islet allo- and xenotransplantation in normal, intercellular adhesion molecule-1-deficient, and P selectin-deficient mice

scientific article published on 01 August 1997

Islet engraftment and revascularization in clinical and experimental transplantation

scientific article

Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation

scientific article published on 31 May 2007

Islets for Research: Nothing Is Perfect, but We Can Do Better

scientific article published on 01 August 2019

Isolated human islets trigger an instant blood mediated inflammatory reaction: implications for intraportal islet transplantation as a treatment for patients with type 1 diabetes

scientific article

Isolation, expansion and functional assessment of CD4+CD25+FoxP3+ regulatory T cells and Tr1 cells from uremic patients awaiting kidney transplantation

scientific article

Key factors for human islet isolation and clinical transplantation

scientific article published in March 2005

Lack of antibody production against Hanganutziu-Deicher (H-D) antigens with N-glycolylneuraminic acid in patients with porcine exposure history

scientific article published on 01 August 2000

Large-scale bioreactor expansion of tumor-infiltrating lymphocytes

scientific article published on 25 November 2010

Large-scale comparison of Liberase HI and collagenase NB1 utilized for human islet isolation

scientific article published on 9 October 2009

Large-scale production of fetal porcine pancreatic isletlike cell clusters. An experimental tool for studies of islet cell differentiation and xenotransplantation

scientific article published on 01 March 1988

Low molecular weight dextran sulfate is well tolerated in humans and increases endogenous expression of islet protective hepatocyte growth factor

scientific article published in December 2008

Low molecular weight dextran sulfate prevents the instant blood-mediated inflammatory reaction induced by adult porcine islets

scientific article published in March 2004

Low molecular weight dextran sulfate: a strong candidate drug to block IBMIR in clinical islet transplantation

scientific article published in February 2006

Low-molecular weight dextran sulfate abrogates the instant blood-mediated inflammatory reaction induced by adult porcine islets both in vitro and in vivo

scientific article published in May 2004

Maturation of in vitro-generated human islets after transplantation in nude mice.

scientific article published on 20 November 2006

Mesenchymal stromal cells support endothelial cell interactions in an intramuscular islet transplantation model

scientific article

Mesenchymal stromal cells to halt the progression of type 1 diabetes?

scientific article published on July 2015

Microbiologic screening as a preparatory step for clinical xenografting of porcine fetal islet-like cell clusters

scientific article published on 01 April 1992

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

scientific article published in January 2017

Modulation of innate immunity in human pancreatic islets infected with enterovirus in vitro

scientific article published in April 2011

Morphologic identification of porcine islet cells three weeks after transplantation into a diabetic patient

scientific article published on 01 June 1994

Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation

scientific article

MyD88-dependent toll-like receptor signalling is not a requirement for fetal islet xenograft rejection in mice

scientific article published in July 2004

National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

scientific article published on 27 July 2016

Natural killer cells determine development of allergen-induced eosinophilic airway inflammation in mice

scientific article published on February 1999

Neutrophilic granulocytes are the predominant cell type infiltrating pancreatic islets in contact with ABO-compatible blood.

scientific article published in October 2005

New class of oxygen carriers improves islet isolation from long-term stored rat pancreata

scientific article published in March 2008

New perspectives on the structure and function of the normal and diabetic beta-cell

scientific article published on January 1991

Nicotinamide inhibits tissue factor expression in isolated human pancreatic islets: implications for clinical islet transplantation

scientific article published in November 2003

No beneficial effect of two-layer storage compared with UW-storage on human islet isolation and transplantation

scientific article published in October 2007

No evidence of infection with porcine endogenous retrovirus in recipients of porcine islet-cell xenografts

Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates

scientific article

Obtaining regulatory T cells from uraemic patients awaiting kidney transplantation for use in clinical trials

scientific article published in August 2013

On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes

scientific article published on 13 September 2019

On the etiology of type 1 diabetes: a new animal model signifying a decisive role for bacteria eliciting an adverse innate immunity response

scientific article

Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation

scientific article published on 01 March 2019

Optimising islet engraftment is critical for successful clinical islet transplantation

scientific article

Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4.

scientific article

Pancreatic islet blood flow after syngeneic pancreaticoduodenal transplantation in rats. Differences between the blood perfusion of the native and the transplanted gland

scientific article published on 01 March 1992

Pancreatic islet transplantation in the human

scientific article published on January 1993

Pancreatic perfusion and subsequent response to glucose in healthy individuals and patients with type 1 diabetes

scientific article

Perfluorohexyloctane improves long-term storage of rat pancreata for subsequent islet isolation

scientific article

Persistent impairment of the insulin response to glucose both in vivo and in vitro after streptozotocin exposure: studies with grafted pancreatic islets and islets maintained in culture

Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

scientific article (publication date: 18 April 2016)

Pig islet xenograft rejection is markedly delayed in macrophage-depleted mice: a study in streptozotocin diabetic animals

scientific article published on 01 August 2000

Pig islet xenotransplantation: activation of porcine endogenous retrovirus in the immediate post-transplantation period

scientific article

Pig pancreas oxygenation at 20 degrees C increases islet ATP generation but deteriorates islet function

scientific article

Pig-to-human islet transplantation in eight patients

scientific article published on 01 April 1994

Polyamine requirements in nicotinamide-stimulated beta-cell differentiation in fetal porcine islet-like cell clusters

scientific article published on 01 October 1994

Porcine islet-like cell clusters cure diabetic nude rats when transplanted under the kidney capsule, but not when implanted into the liver or spleen

scientific article published on 01 January 1994

Porcine islets of langerhans isolated from normal and hDAF transgenic pigs elicit the same acute inflammatory reaction during exposure to human blood; inhibition of the response with soluble complement receptor 1 and heparin

scientific article published on 01 August 2000

Positron Emission Tomography to Assess the Outcome of Intraportal Islet Transplantation

scientific article published on 20 June 2016

Positron emission tomography imaging of the glucagon-like peptide-1 receptor in healthy and streptozotocin-induced diabetic pigs.

scientific article published on 19 March 2014

Positron emission tomography in clinical islet transplantation

scientific article published on 21 October 2009

Positron emission tomography: a real-time tool to quantify early islet engraftment in a preclinical large animal model

scientific article published in October 2007

Possible Transmission of Zoonoses in Xenotransplantation: Porcine Endogenous Retroviruses (PERVs) from an Immunological Point of View

article

Possible transmission of zoonoses in xenotransplantation: porcine endogenous retroviruses (PERVs) from an immunological point of view

scientific article published in January 2004

Pre-clinical evaluation of [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 for imaging of insulinoma

scientific article

Pre-transplantation 31P-magnetic resonance spectroscopy for quality assessment of human pancreatic grafts - A feasibility study

scientific article published on 7 February 2017

Preclinical evaluation of a 68Ga-labeled biotin analogue for applications in islet transplantation.

scientific article published in December 2011

Preparatory studies of composite mesenchymal stem cell islets for application in intraportal islet transplantation

scientific article

Preserved β-cell function in type 1 diabetes by mesenchymal stromal cells

scientific article published on 9 September 2014

Pretreatment of fetal porcine pancreas in culture with nicotinamide accelerates reversal of diabetes after transplantation to nude mice

scientific article published on 01 February 1993

Procurement of human pancreases for islet isolation-the initiation of a Scandinavian collaborative network

scientific article published on 01 June 2001

Protective effect of FK-506 in pig-to-rat islet xenotransplantation is abrogated by prednisolone

scientific article published on 01 August 2000

Purification of regulatory T cells with the use of a fully enclosed high-speed microfluidic system.

scientific article published on 22 July 2014

Purified Human Pancreatic Islets, CIT Culture Media with Lisofylline or Exenatide

article

Quality of isolated pig islets is improved using perfluorohexyloctane for pancreas storage in a split lobe model

scientific article published on 4 October 2012

Quantification of lymphocytes propagating from rat-kidney allografts--a tool to monitor anti-rejection treatment

scientific article published on 01 June 2002

Quantification of the islet product: presentation of a standardized current good manufacturing practices compliant system with minimal variability

scientific article

Quantifying the Effects of Different Neutral Proteases on Human Islet Integrity

scientific article published in November 2017

Quantitative imaging of serotonergic biosynthesis and degradation in the endocrine pancreas

scientific article published on 13 February 2014

Refinement of the automated method for human islet isolation and presentation of a closed system for in vitro islet culture

scientific article published in November 2004

Reinnervation of syngeneic mouse pancreatic islets transplanted into renal subcapsular space

scientific article published on 01 February 1992

Reinnervation of syngeneic pancreatico-duodenal grafts in rats

scientific article

Reinnervation of transplanted fetal porcine endocrine pancreas. Evidence for initial growth and subsequent degeneration of nerve fibers in the islet grafts

scientific article published on 01 August 1996

Reinnervation of transplanted mouse pancreatic islets

scientific article published on 01 February 1991

Reinnervation of transplanted pancreatic islets. A comparison among islets implanted into the kidney, spleen, and liver

scientific article published on 01 July 1993

Reinnervation of transplanted pancreatic islets: a comparison between islets implanted into the kidney, spleen, or liver.

scientific article

Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement

scientific article

Resolvin E1 reduces proinflammatory markers in human pancreatic islets in vitro

scientific article published on 29 January 2010

Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease

scientific article published on April 2013

Role of macrophage migration inhibitory factor (MIF) in allergic and endotoxin-induced airway inflammation in mice

scientific article published on January 2000

Role of macrophages and natural killer cells in the rejection of pig islet xenografts in mice

scientific article published on 01 August 2000

Soluble complement receptor 1 (TP10) preserves adult porcine islet morphology after intraportal transplantation into cynomolgus monkeys

scientific article published on 01 February 2001

Specificity of human xenoantibodies formed in response to fetal porcine isletlike cell clusters

scientific article published on 01 June 1994

Suppression of T cells results in long-term survival of mouse heart xenografts in C6-deficient rats

scientific article published in November 2001

Sustained reversal of diabetes following islet transplantation to striated musculature in the rat

scientific journal article

Synthesis and biological evaluation of [¹¹C]AZ12504948; a novel tracer for imaging of glucokinase in pancreas and liver.

scientific article published on 6 December 2014

T cell control of primary and latent cytomegalovirus infections in healthy subjects.

scientific article published in September 2005

Teplizumab in Relatives at Risk for Type 1 Diabetes

The ADP/ATP ratio: A novel predictive assay for quality assessment of isolated pancreatic islets

scientific article published on 26 July 2006

The CD4+ effector cell in islet xenotransplantation is a macrophage and not a T-lymphocyte

scientific article published on 01 February 1995

The development of a GPR44 targeting radioligand [C]AZ12204657 for in vivo assessment of beta cell mass

article

The diagnosis of insulitis in human type 1 diabetes.

scientific article

The effect of macrophage depletion on delayed xenograft rejection: studies in the guinea pig-to-C6-deficient rat heart transplantation model

scientific article published in November 1999

The effects of exendin-4 treatment on graft failure: an animal study using a novel re-vascularized minimal human islet transplant model

scientific article (publication date: 2015)

The efficacy of CD40 ligand blockade in discordant pig-to-rat islet xenotransplantation is correlated with an immunosuppressive effect of immunoglobulin

scientific article published in January 2005

The human pancreas proteome defined by transcriptomics and antibody-based profiling

scientific article

The importance of tryptic-like activity in purified enzyme blends for efficient islet isolation

scientific article

The main infiltrating cell in xenograft rejection is a CD4+ macrophage and not a T lymphocyte

scientific article published on 01 September 1995

The recent finding that tissue factor is produced by the pancreatic islets constitutes a possible link between insulin resistance and cardiovascular disease

scientific article

The role of vitamin D in the aetiology of type 1 diabetes

scientific article published on 10 February 2020

The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro.

scientific article published on 5 May 2009

The transplanted fetal endocrine pancreas undergoes an inherent sequential differentiation similar to that in the native pancreas. An ultrastructural study in the pig-to-mouse model

scientific article published on 01 May 2001

Tissue culture of human fetal pancreas. Effects of nicotinamide on insulin production and formation of isletlike cell clusters

scientific article published on 01 January 1989

Tissue culture of human fetal pancreas: growth hormone stimulates the formation and insulin production of islet-like cell clusters

scientific article published on 01 December 1987

Toward clinical trials of islet xenotransplantation

scientific article

Transcriptional analysis of islets of Langerhans from organ donors of different ages

scientific article published on 12 March 2021

Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism

scientific article published on 18 December 2020

Transplantation of Macro-encapsulated Human Islets within the Bioartificial Pancreas β Air to Patients with Type 1 Diabetes Mellitus

scientific article published on 29 December 2017

Transplantation of discordant xenogeneic endocrine pancreatic cell clusters into the liver: effects on coagulation, liver function, and hepatic hemodynamics. A safety study in the pig to dog model

scientific article published on 01 April 1992

Transplantation of fetal porcine pancreas to diabetic or normoglycemic nude mice. Evidence of a rapid engraftment process demonstrated by blood flow and heat shock protein 70 measurements

scientific article published on 01 June 1995

Transplantation of porcine fetal islet-like cell clusters into eight diabetic patients

scientific article published on 01 February 1993

Transplantation of porcine fetal islet-like cell clusters to three diabetic patients

scientific article published on 01 April 1992

Transplantation of porcine fetal pancreas to a diabetic patient

scientific article published on 01 February 1992

Transplantation of porcine fetal pancreas to diabetic patients

scientific article published on 01 November 1994

Transplanted functional islet mass: donor, islet preparation, and recipient factors influence early graft function in islet-after-kidney patients

scientific article published in March 2012

Treatment efficacy and immune stimulation by AdCD40L gene therapy of spontaneous canine malignant melanoma

scientific article published on July 2013

Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids

scientific article published on 18 January 2016

Tribute to Carl-Gustav Groth (1933-2014), first president of the International Xenotransplantation Association

scientific article published in March 2014

Triple drug treatment with cyclosporine, leflunomide and mycophenolate mofetil prevents rejection of pig islets transplanted into rats and primates

scientific article published on 01 August 1997

Tropism Analysis of Two Coxsackie B5 Strains Reveals Virus Growth in Human Primary Pancreatic Islets but not in Exocrine Cell Clusters In Vitro

scientific article published on 5 April 2013

Type 1 Diabetes Mellitus Donor Mesenchymal Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro

scientific article published on 13 July 2016

Ultrastructural evidence for blood microvessels devoid of an endothelial cell lining in transplanted pancreatic islets.

scientific article published on February 1995

Ultrastructural identification of cells expressing Galalpha1-3Gal antigen in cultured fetal porcine isletlike cell clusters

scientific article published on 01 August 2000

Unique basement membrane structure of human pancreatic islets: implications for beta-cell growth and differentiation.

scientific article published in November 2008

Using HTK for prolonged pancreas preservation prior to human islet isolation

scientific article published on 31 March 2011

Validity of urinary C-peptide determinations in xenogeneic islet transplantation

scientific article published on 01 June 1994

Washout kinetics of blood cells from the perfused pancreas of normoglycemic and diabetic rats

scientific article published on 01 January 1994

Whole pancreatic and islet blood flow after syngeneic pancreaticoduodenal transplantation in the rat

scientific article published on 01 June 1992

Xenograft rejection of fetal porcine islet-like cell clusters in the rat: effects of active and passive immunization

scientific article published on 01 November 1999

Xenograft rejection of porcine islet-like cell clusters in immunoglobulin- or Fc-receptor gamma-deficient mice.

scientific article published in November 1996

Xenograft rejection of porcine islet-like cell clusters in normal and natural killer cell-depleted mice

scientific article published on May 1996

Xenograft rejection of porcine islet-like cell clusters in normal, interferon-gamma, and interferon-gamma receptor deficient mice.

scientific article published in May 1997

Xenoislet rejection following pig-to-rat, pig-to-primate, and pig-to-man transplantation

scientific article published on 01 April 1996

[11C]5-hydroxy-tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes.

scientific article published on 28 February 2017

[Swedish medical research does not need more control]

γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes

scientific article

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