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List of works by Gunilla Westergren-Thorsson

2DDB - a bioinformatics solution for analysis of quantitative proteomics data

scientific article

5-HT2B receptor antagonists attenuate myofibroblast differentiation and subsequent fibrotic responses in vitro and in vivo

scientific article published on August 2016

A proteomic approach to mimic fibrosis disease evolvement by an in vitro cell line

scientific article

Aberrant nonfibrotic parenchyma in idiopathic pulmonary fibrosis is correlated with decreased β-catenin inhibition and increased Wnt5a/b interaction

scientific article published on March 2016

Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma

scientific article published on 18 September 2014

Activated MCTC mast cells infiltrate diseased lung areas in cystic fibrosis and idiopathic pulmonary fibrosis

scientific article published on 20 October 2011

Activation of platelet-derived growth factor pathway in human asthmatic pulmonary-derived mesenchymal cells

scientific article

Acute lung injury in acute pancreatitis – Awaiting the big leap ⬇️

scientific article published on June 29, 2012

Altered expression of small proteoglycans, collagen, and transforming growth factor-beta 1 in developing bleomycin-induced pulmonary fibrosis in rats.

scientific article

Altered fibroblast proteoglycan production in COPD.

scientific article

Antiproliferative Heparan Sulfate Inhibiting Hyaluronan and Transforming Growth Factor-β Expression in Human Lung Fibroblast Cells: A Possible Antifibrotic Therapy?

Biglycan and decorin induce morphological and cytoskeletal changes involving signalling by the small GTPases RhoA and Rac1 resulting in lung fibroblast migration

scientific article published in December 2003

Biglycan isoforms with differences in polysaccharide substitution and core protein in human lung fibroblasts

scientific article

Binding, internalization, and degradation of antiproliferative heparan sulfate by human embryonic lung fibroblasts

scientific article published on 01 March 1997

Biomarkers from bronchoalveolar lavage fluid in systemic sclerosis patients with interstitial lung disease relate to severity of lung fibrosis.

scientific article published on 6 May 2013

Bronchial extracellular matrix from COPD patients induces altered gene expression in repopulated primary human bronchial epithelial cells

scientific article published on 22 February 2018

Budesonide/formoterol effects on metalloproteolytic balance in TGFbeta-activated human lung fibroblasts

scientific article published on 17 April 2009

Changes in paraurethral connective tissue at menopause are counteracted by estrogen.

scientific article published in July 1996

Concise Review: The Bystander Effect: Mesenchymal Stem Cell-Mediated Lung Repair

scientific article published on 17 March 2016

Controlled and uncontrolled asthma display distinct alveolar tissue matrix compositions

scientific article

Correlation between airway responsiveness and proteoglycan production by bronchial fibroblasts from normal and asthmatic subjects

scientific article

Crosstalk between Mast Cells and Lung Fibroblasts Is Modified by Alveolar Extracellular Matrix and Influences Epithelial Migration

scientific article published on 06 January 2021

Cytokine regulation of proteoglycan production in fibroblasts: separate and synergistic effects

scientific article published on 01 March 1997

Defective alterations in the collagen network to prostacyclin in COPD lung fibroblasts ⬇️

scientific article published on February 14, 2013

Differential expressions of mRNA for proteoglycans, collagens and transforming growth factor-beta in the human cervix during pregnancy and involution.

scientific article

Disubstituted naphthyl β-D-xylopyranosides: Synthesis, GAG priming, and histone acetyltransferase (HAT) inhibition

scientific article

Early extracellular matrix changes are associated with later development of bronchiolitis obliterans syndrome after lung transplantation

scientific article

Effects of 5-HT2 receptor antagonists on bronchoconstriction and pulmonary remodeling processes

scientific article published on 15 February 2018

Endoplasmic reticulum, Golgi, and lysosomes are disorganized in lung fibroblasts from chronic obstructive pulmonary disease patients

scientific article published in March 2018

Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients

scientific article

Epithelial G protein-coupled receptor kinases regulate the initial inflammatory response during mycobacterial infection ⬇️

scientific article published on November 28, 2012

Exploration of the active site of β4GalT7: modifications of the aglycon of aromatic xylosides

scientific article published in March 2015

Expression, activity and localization of lysosomal sulfatases in Chronic Obstructive Pulmonary Disease

scientific article published in Scientific Reports

Extracellular matrix alterations and acute inflammation; developing in parallel during early induction of pulmonary fibrosis ⬇️

scientific article published on April 2, 2012

Fibrocytes and the tissue niche in lung repair ⬇️

scientific article published on 09 June 2011

Fibrocytes are associated with vascular and parenchymal remodelling in patients with obliterative bronchiolitis

scientific article published on 30 October 2009

Functional and phenotypical comparison of myofibroblasts derived from biopsies and bronchoalveolar lavage in mild asthma and scleroderma

scientific article

Haemophilus influenzae P4 Interacts With Extracellular Matrix Proteins Promoting Adhesion and Serum Resistance

scientific article

Heparan/chondroitin/dermatan sulfate primer 2-(6-hydroxynaphthyl)-O-beta-D-xylopyranoside preferentially inhibits growth of transformed cells.

scientific article published on March 1998

Human cervical ripening, an inflammatory process mediated by cytokines

scientific article published on 01 April 2000

Increased deposition of glycosaminoglycans and altered structure of heparan sulfate in idiopathic pulmonary fibrosis

scientific article published on 11 December 2016

Innate Immune Responses after Airway Epithelial Stimulation with Mycobacterium bovis Bacille-Calmette Guérin

scientific article

Interleukin-15 attenuates transforming growth factor-β1-induced myofibroblast differentiation in human fetal lung fibroblasts

scientific article published on August 24, 2010

L-iduronate-rich glycosaminoglycans inhibit growth of normal fibroblasts independently of serum or added growth factors

scientific article published on May 1993

Limited impact of fibromodulin deficiency on the development of experimental skin fibrosis

scientific article published in July 2016

Lung fibroblast clones from normal and fibrotic subjects differ in hyaluronan and decorin production and rate of proliferation

scientific article

Lung fibroblast proteoglycan production induced by serum is inhibited by budesonide and formoterol

scientific article published on 15 September 2005

MSC from fetal and adult lungs possess lung-specific properties compared to bone marrow-derived MSC

scientific article published on 6 July 2016

Mast cells and mast cell tryptase enhance migration of human lung fibroblasts through protease-activated receptor 2

scholarly article by Mariam Bagher published in September 2018

Mycobacteria Manipulate G-Protein-Coupled Receptors to Increase Mucosal Rac1 Expression in the Lungs

scientific article published on 24 December 2016

Mycobacteria bypass mucosal NF-kB signalling to induce an epithelial anti-inflammatory IL-22 and IL-10 response

scientific article published on 28 January 2014

Mycobacterium bovis bacilli Calmette-Guerin regulates leukocyte recruitment by modulating alveolar inflammatory responses ⬇️

scientific article published on November 4, 2011

Myofibroblast accumulation correlates with the formation of fibrotic tissue in a rat air pouch model.

scientific article published in August 2002

Nanocapillary liquid chromatography interfaced to tandem matrix-assisted laser desorption/ionization and electrospray ionization-mass spectrometry: mapping the nuclear proteome of human fibroblasts

scientific article published in November 2003

Nontypeable Haemophilus influenzae adhesin protein E: characterization and biological activity

scientific article

Pathological airway remodelling in inflammation

scientific article published in May 2010

Proliferation of cultured fibroblasts is inhibited by L-iduronate-containing glycosaminoglycans

scientific article published on 01 June 1991

Proteoglycan and proteome profiling of central human pulmonary fibrotic tissue utilizing miniaturized sample preparation: a feasibility study

scientific article

Proteoglycan production in disomic and trisomy 7-carrying human synovial cells.

scientific article

Proteome annotations and identifications of the human pulmonary fibroblast

scientific article

Proteomic 2DE database for spot selection, automated annotation, and data analysis

scientific article

Proteomics -- the protein expression technology to study connective tissue biology.

scientific article

Pulmonary fibrosis in vivo displays increased p21 expression reduced by 5-HT2B receptor antagonists in vitro - a potential pathway affecting proliferation

scientific article published on 31 January 2018

Pulmonary vascular changes in asthma and COPD.

scientific article

Quantifying extracellular matrix turnover in human lung scaffold cultures

scientific article published on 3 April 2018

Quantitative proteomic analysis of fibroblast nuclear proteins after stimulation with mitogen activated protein kinase inhibiting heparan sulfate

scientific article

Quantitative proteomic characterization of lung-MSC and bone marrow-MSC using DIA-mass spectrometry

scientific article published on 24 August 2017

Quantitative proteomic characterization of the lung extracellular matrix in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

scientific article published in March 2018

Regulation of the chondroitin/dermatan fine structure by transforming growth factor-beta1 through effects on polymer-modifying enzymes

scientific article published on 23 August 2005

Relationship between matrix production by bronchial fibroblasts and lung function and AHR in asthma

scientific article

Specific haptoglobin expression in bronchoalveolar lavage during differentiation of circulating fibroblast progenitor cells in mild asthma

scientific article

Specific subsets of mesenchymal stroma cells to treat lung disorders--finding the Holy Grail

scientific article

Splicosomal and serine and arginine-rich splicing factors as targets for TGF-β.

scientific article published on 28 April 2012

TGF-beta enhances the production of hyaluronan in human lung but not in skin fibroblasts

scientific article

TGFβ-induced matrix production by bronchial fibroblasts in asthma: Budesonide and formoterol effects ⬇️

scientific article published on April 21, 2011

The Pulmonary Extracellular Matrix Is a Bactericidal Barrier Against in Chronic Obstructive Pulmonary Disease (COPD): Implications for an Innate Host Defense Function of Collagen VI

scholarly article by Suado M Abdillahi et al published 2018 in Frontiers in Immunology

The Respiratory Pathogen Moraxella catarrhalis Targets Collagen for Maximal Adherence to Host Tissues

scientific article published on 22 March 2016

The extracellular matrix - the under-recognized element in lung disease?

scientific article

The importance of fibroblasts in remodelling of the human uterine cervix during pregnancy and parturition

scientific article

The synthesis of a family of structurally related proteoglycans in fibroblasts is differently regulated by TFG-beta

scientific article published in June 1991

Tissue fibrocytes in patients with mild asthma: a possible link to thickness of reticular basement membrane?

scientific article published on 29 March 2006

Transforming growth factor-beta induces selective increase of proteoglycan production and changes in the copolymeric structure of dermatan sulphate in human skin fibroblasts

scientific article published on 01 April 1992

Tumour necrosis factor-alpha interacts with biglycan and decorin

scientific article

Uncontrolled Asthmatics Have Increased FceRI+ and TGF-β Positive MCTC Mast Cells and Collagen VI in the Alveolar Parenchyma

scientific article

VEGF synthesis is induced by prostacyclin and TGF-β in distal lung fibroblasts from COPD patients and control subjects: Implications for pulmonary vascular remodelling

scientific article

Versican accumulates in vascular lesions in pulmonary arterial hypertension

scientific article published on September 2016

Versican in inflammation and tissue remodeling: the impact on lung disorders

scientific article

Viral Stimuli Trigger Exaggerated Thymic Stromal Lymphopoietin Expression by Chronic Obstructive Pulmonary Disease Epithelium: Role of Endosomal TLR3 and Cytosolic RIG-I-Like Helicases ⬇️

scientific article published on June 20, 2011

iNOS affects matrix production in distal lung fibroblasts from patients with mild asthma

scientific article published on 8 September 2015

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