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List of works by Christopher S. Chen

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Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment

scientific article
Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

scientific article
Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

scientific article
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues

scientific article
Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

scientific article published on 24 March 2013
Emergent patterns of growth controlled by multicellular form and mechanics

scientific article
Mechanical tugging force regulates the size of cell-cell junctions

scientific article
Measurement of mechanical tractions exerted by cells in three-dimensional matrices.

scientific article
Control of Cyclin D1, p27Kip1, and Cell Cycle Progression in Human Capillary Endothelial Cells by Cell Shape and Cytoskeletal Tension

scientific article published on November 1, 1998
A hitchhiker's guide to mechanobiology

scientific article published on July 2011
A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues

scientific article published on 4 January 2012
Cellular control lies in the balance of forces

scientific article published on April 1, 1998
Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition

scientific article published on 11 January 2012
Emergence of patterned stem cell differentiation within multicellular structures

scientific article published on 14 August 2008
Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro

scientific article
HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

scientific article
Magnetic microposts as an approach to apply forces to living cells

scientific article
Clopidogrel plus aspirin versus aspirin alone for reducing embolisation in patients with acute symptomatic cerebral or carotid artery stenosis (CLAIR study): a randomised, open-label, blinded-endpoint trial

scientific article published on March 22, 2010
Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid

scientific article published on 16 July 2006
Cell polarity triggered by cell-cell adhesion via E-cadherin

scientific article
The Montreal Cognitive Assessment (MoCA) is superior to the Mini-Mental State Examination (MMSE) for the detection of vascular cognitive impairment after acute stroke

scientific article published in December 2010
Cell shape and substrate rigidity both regulate cell stiffness

scientific article
Diagnostic criteria for vascular cognitive disorders: a VASCOG statement

scientific article
Cytoskeleton-based forecasting of stem cell lineage fates

scientific article
Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions

scientific article published on 31 December 2012
Activation of ROCK by RhoA is regulated by cell adhesion, shape, and cytoskeletal tension

scientific article
Bioresponsive mesoporous silica nanoparticles for triggered drug release

scientific article published on 18 November 2011
Bone morphogenetic protein-2-induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tension

scientific article
Nanotechnology for cell-substrate interactions

scientific article
Simple approach to micropattern cells on common culture substrates by tuning substrate wettability

scientific article published in May 2004
How vinculin regulates force transmission

scientific article published on 28 May 2013
Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments

scientific article
Repositioning of cells by mechanotaxis on surfaces with micropatterned Young's modulus

scientific article published on September 2003
Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA.

scientific article
Fluid shear stress threshold regulates angiogenic sprouting

scientific article
An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling

scientific article
Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)
Measuring cell-generated forces: a guide to the available tools

scientific article
Formation and optogenetic control of engineered 3D skeletal muscle bioactuators

scientific article
Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial

scientific article published on October 21, 2014
Endothelial cell sensing of flow direction

scientific article
Bioactive hydrogels made from step-growth derived PEG-peptide macromers

scientific article
Long-range force transmission in fibrous matrices enabled by tension-driven alignment of fibers

scientific article
Geometric control of vascular networks to enhance engineered tissue integration and function

scientific article published on 22 April 2013
Geometrically Controlled Endothelial Tubulogenesis in Micropatterned Gels

scientific article published on July 1, 2010
A DNA-based molecular probe for optically reporting cellular traction forces

scientific article
Cell traction forces direct fibronectin matrix assembly

scientific article published on January 2009
Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI

scientific article published on 7 February 2015
VE-cadherin simultaneously stimulates and inhibits cell proliferation by altering cytoskeletal structure and tension

scientific article published on 22 July 2003
Cadherins, RhoA, and Rac1 are differentially required for stretch-mediated proliferation in endothelial versus smooth muscle cells

scientific article published on 21 August 2007

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