List of works by Firas S Zetoune

Acute lung injury induced by lipopolysaccharide is independent of complement activation

scientific article published on June 2008

An essential role for complement C5a in the pathogenesis of septic cardiac dysfunction

scientific article

Anti-complement Strategies in Experimental Sepsis

scientific article published on January 1, 2003

Anti-inflammatory effects of β2 adrenergic receptor agonists in experimental acute lung injury

scientific article published on 7 February 2012

Attenuation of IgG immune complex-induced acute lung injury by silencing C5aR in lung epithelial cells

scientific article published on 20 July 2009

Bidirectional Crosstalk between C5a Receptors and the NLRP3 Inflammasome in Macrophages and Monocytes

scientific article published on 07 June 2016

CD11c+ alveolar macrophages are a source of IL-23 during lipopolysaccharide-induced acute lung injury

scientific article published on May 2013

Changes and regulation of the C5a receptor on neutrophils during septic shock in humans

scientific article published on 11 March 2013

Changes in the novel orphan, C5a receptor (C5L2), during experimental sepsis and sepsis in humans

scientific article

Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro

scientific article

Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages

scientific article

Complement dependency of cardiomyocyte release of mediators during sepsis

scientific article

Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction

scientific article published on June 2017

Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis

scientific article published on 19 August 2016

Critical role for the NLRP3 inflammasome during acute lung injury

scientific article

Cross-talk between TLR4 and FcgammaReceptorIII (CD16) pathways

scientific article

Cutting edge: critical role for C5aRs in the development of septic lymphopenia in mice

scientific article

Evidence for a functional role of the second C5a receptor C5L2.

scientific article

Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis

scientific article published on 27 December 2011

Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury

scientific article published on 27 August 2013

Functional roles for C5a receptors in sepsis

scientific article published on 04 May 2008

Functions of the complement components C3 and C5 during sepsis

scientific article published on 27 June 2008

Generation of C5a by phagocytic cells

scientific article published on November 2002

Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis

article published in 2018

In vivo regulation of neutrophil apoptosis by C5a during sepsis.

scientific article

Increased C5a receptor expression in sepsis

scientific article

Increased C5a receptor expression in sepsis

Induction of M2 regulatory macrophages through the β2-adrenergic receptor with protection during endotoxemia and acute lung injury

scientific article

Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3.

scientific article

Murine complement interactions with Pseudomonas aeruginosa and their consequences during pneumonia

scientific article

MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway

scientific article published on 22 August 2011

Neutrophil C5a receptor and the outcome in a rat model of sepsis

scientific article published in August 2003

Organ distribution of histones after intravenous infusion of FITC histones or after sepsis

scientific article

Persistent neutrophil dysfunction and suppression of acute lung injury in mice following cecal ligation and puncture sepsis

scientific article

Regulation by C5a of neutrophil activation during sepsis

scientific article

Regulation of IL-17 family members by adrenal hormones during experimental sepsis in mice

scientific article published on April 2013

Regulatory role of C5a on macrophage migration inhibitory factor release from neutrophils

scientific article published in July 2004

Relationship of acute lung inflammatory injury to Fas/FasL system

scientific article

Role of extracellular histones in the cardiomyopathy of sepsis.

scientific article published on 13 February 2015

Selective Biological Responses of Phagocytes and Lungs to Purified Histones

scientific article published on 8 February 2017

Stat3 activation in acute lung injury

scientific article published in June 2004

Structure-function relationships of human C5a and C5aR.

scientific article

The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation

scientific article published on 13 May 2013

The outcome of polymicrobial sepsis is independent of T and B cells

scientific article

Zonulin as prehaptoglobin2 regulates lung permeability and activates the complement system

scientific article published on 05 April 2013