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List of works by Thomas Unger

2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-(1S,3S,5S)-2- azabicyclo[3.3.0]octane-3-carboxylic acid (Hoe 498): antihypertensive action and persistent inhibition of tissue converting enzyme activity in spontaneously hypertensive rats

scientific article published on January 1, 1984

4C.02: PROLONGED ANGIOTENSIN II-INDUCED HYPERTENSION IMPAIRS SHORT-TERM MEMORY IN ADULT MICE.

scientific article

A Novel Orally Active Converting-Enzyme Inhibitor Ys 980: Effects on Blood Pressure in Spontaneously Hypertensive Rats ⬇️

scientific article published on December 1, 1979

A new formalin test allowing stimulaneous evaluation of cardiovascular and nociceptive responses

scientific article published on October 1, 1997

A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein

scientific article

ANG III induces expression of inducible transcription factors of AP-1 and Krox families in rat brain

scientific article published on 5 May 2005

AT(2) receptor and tissue injury: therapeutic implications

scientific article published on February 2014

AT1 receptor antagonist telmisartan administered peripherally inhibits central responses to angiotensin II in conscious rats.

scientific article published in July 2001

AT1-receptor blockade attenuates outward aortic remodeling associated with diet-induced obesity in mice

scientific article published on 23 June 2017

AT2 receptor agonists: hypertension and beyond

scientific article published on March 2012

AT2 receptors in cardiovascular and renal diseases

scientific article

AT2 receptors targeting cardiac protection post-myocardial infarction

scientific article published on July 2014

AT2-receptor stimulation enhances axonal plasticity after spinal cord injury by upregulating BDNF expression

scientific article published on 19 November 2012

AT2R agonist, compound 21, is reno-protective against type 1 diabetic nephropathy

scientific article published on 16 March 2015

ATR (Angiotensin AT2 Receptor) Agonist, Compound 21, Prevents Abdominal Aortic Aneurysm Progression in the Rat

scientific article published on 01 September 2018

Activation of intracellular angiotensin AT₂ receptors induces rapid cell death in human uterine leiomyosarcoma cells

scientific article

Activity profile of calpains I and II in chronically infarcted rat myocardium--influence of the calpain inhibitor CAL 9961.

scientific article published on April 2002

Acute sino-aortic denervation in rats produces a selective increase of adrenaline turnover in the dorsal midline area of the caudal medulla oblongata and a reduction of adrenaline levels in the anterior and posterior hypothalamus

scientific article published on January 1981

Adapter proteins and promoter regulation of the angiotensin AT2 receptor--implications for cardiac pathophysiology

scientific article published on 16 September 2009

Advances in cardiovascular research. 15th Annual Meeting of the European Council for Cardiovascular Research (ECCR). La Colle sur Loup, France, 8–10 October 2010.

scientific article

Alpha atrial natriuretic peptide concentrations in plasma of children with congenital heart and pulmonary diseases.

scientific article

Altered neuropeptide concentrations in spontaneously hypertensive rats: cause or consequence?

scientific article

An update on telmisartan/hydrochlorothiazide combinations for the management of hypertensive patients with additional cardiovascular risk factors

scientific article published on June 2013

Angiotensin AT1/AT2 receptors: regulation, signalling and function

scientific article

Angiotensin AT2-receptor stimulation improves survival and neurological outcome after experimental stroke in mice

scientific article

Angiotensin AT2Receptor Degradation Is Prevented by Ligand Occupation ⬇️

scientific article published on February 4, 1998

Angiotensin II AT(1)-receptor induces biglycan in neonatal cardiac fibroblasts via autocrine release of TGFbeta in vitro

scientific article

Angiotensin II and atrial natriuretic peptide in the brain: effects on volume and Na+ balance

scientific article published on December 1989

Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation

scientific article published on 30 June 2005

Angiotensin II receptor blockade and end-organ protection

scientific article

Angiotensin II receptor expression: from maturation to pathogenesis

scientific article published in July 2003

Angiotensin II receptor pharmacology and AT1-receptor blockers

scientific article

Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection

scientific article published in February 2005

Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction?

scientific article

Angiotensin II type 2 receptors: signalling and pathophysiological role

scientific article

Angiotensin as neuromodulator/neurotransmitter in central control of body fluid and electrolyte homeostasis

scientific article published on January 1995

Angiotensin biosynthesis and concentrations in brain of normotensive and hypertensive rats

scientific article published on January 1, 1984

Angiotensin converting enzyme inhibitors, left ventricular hypertrophy and fibrosis

scientific article published on June 1995

Angiotensin receptor blockers and cerebral protection in stroke

scientific article

Angiotensin receptor blockers: therapeutic targets and cardiovascular protection

scientific article

Angiotensin receptor subtypes in the brain

scientific article published in September 1992

Angiotensin receptors

scientific article published on December 1996

Angiotensin receptors and autophagy: live and let die.

scientific article published on 11 May 2009

Angiotensin receptors in the brain

scientific article published on November 1995

Angiotensin stimulates β-endorphin release from anterior pituitary gland cell cultures of rats ⬇️

scientific article published on April 20, 1984

Angiotensin synthesis in the brain and increased turnover in hypertensive rats

scientific article published in August 1983

Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity

scientific article published on 26 April 2004

Angiotensin type 2 receptor (AT2R) and receptor Mas: a complex liaison

scientific article

Angiotensin type 2 receptor stimulation ameliorates left ventricular fibrosis and dysfunction via regulation of tissue inhibitor of matrix metalloproteinase 1/matrix metalloproteinase 9 axis and transforming growth factor β1 in the rat heart

scientific article published on 30 December 2013

Angiotensin type 2 receptor stimulation increases renal function in female, but not male, spontaneously hypertensive rats

scientific article published on 19 May 2014

Angiotensin type 2 receptors: blood pressure regulation and end organ damage

scientific article

Angiotensin-induced hypertension in the rat. Sympathetic nerve activity and prostaglandins

scientific article

Angiotensin-like activity in resistance vessels. Immunocytochemical study in Chinese hamsters.

scientific article

Antihypertensive Effects of the Novel Converting-Enzyme Inhibitor YS 980 in Spontaneously Hypertensive Rats ⬇️

scientific article published on January 1, 1981

Antihypertensive action and inhibition of tissue conversion enzyme by ramipril, perindopril and enalapril in the spontaneously hypertensive rat (SHRSP)

scientific article published on June 1986

Antihypertensive action and inhibition of tissue converting enzyme (CE) by three prodrug CE inhibitors, enalapril, ramipril and perindopril in stroke-prone spontaneously hypertensive rats

scientific article published on October 1986

Antihypertensive action of the converting enzyme inhibitor perindopril (S9490-3) in spontaneously hypertensive rats: comparison with enalapril (MK421) and ramipril (Hoe498).

scientific article published in March 1986

Antihypertensive and cardioprotective effects after angiotensin-converting enzyme inhibition: Role of kinins ⬇️

scientific article published on June 1, 1997

Antihypertensive effect of the GABA receptor agonist muscimol in spontaneously hypertensive rats. Role of the sympathoadrenal axis

scientific article published in January 1984

Antihypertensives as over-the-counter drugs?

scientific article published on 29 October 2009

Are angiotensin receptor blockers neuroprotective?

scientific article published in August 2004

Are renal mechanisms involved in primary hypertension? Evidence from kidney transplantation studies in rats

scientific article published on September 1991

Atrial natriuretic peptide (ANP) as a neuropeptide: interaction with angiotensin II on volume control and renal sodium handling

scientific article published on January 1990

Atrial natriuretic peptide: a new factor in blood pressure control

scientific article

Blocking the tissue renin-angiotensin system: the future cornerstone of therapy

scientific article

Bradykinin B1 and B2 receptors differentially regulate cardiac Na+-H+ exchanger, Na+-Ca2+ exchanger and Na+-HCO3- symporter

scientific article

Brain angiotensin II: localization and possible functions

scientific article published on January 1987

Brain angiotensin: on the way to becoming a well-studied neuropeptide system ⬇️

scientific article published on November 15, 1984

Brain angiotensin: pathways and pharmacology

scientific article published on June 1988

Brain angiotensin: receptors, actions and possible role in hypertension

scientific article published on June 1992

Brain peptides and blood pressure control.

scientific article published in January 1987

Calcium channel blockade limits transcriptional, translational and functional up-regulation of the cardiac calpain system after myocardial infarction

scientific article published in October 2002

Candesartan but not ramipril pretreatment improves outcome after stroke and stimulates neurotrophin BNDF/TrkB system in rats

scientific article

Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome

scientific article published in May 2013

Cardiac PPARalpha expression in patients with dilated cardiomyopathy

scientific article published on 22 November 2005

Cardiac c-kit+AT2+ cell population is increased in response to ischemic injury and supports cardiomyocyte performance.

scientific article

Cardiac inflammation after local irradiation is influenced by the kallikrein-kinin system

scientific article

Cardioprotective effects by ramipril after ischemia and reperfusion in animal experiment studies

scientific article published on January 1994

Cardiovascular and renal effects of atrial natriuretic factor

scientific article

Cardiovascular protection for all individuals at high risk: evidence-based best practice

scientific article published on 23 August 2008

Carotid chemoreceptors, systemic blood pressure, and chronic episodic hypoxia mimicking sleep apnea ⬇️

scientific article published on May 1, 1992

Catecholamine turnover changes in hypothalamus and dorsal midline area of the caudal medulla oblongata of spontaneously hypertensive rats

scientific article published on 01 December 1979

Catecholaminergic pathway involved in angiotensin II-induced vasopressin release

scientific article published on December 1, 1991

Central Effects of Converting Enzyme Inhibitors ⬇️

scientific article published on January 1, 1983

Central angiotensin AT1 and muscarinic receptors in ITF expression on intracerebroventricular NaCl ⬇️

scientific article published on July 1, 1998

Central cardiovascular actions of vasopressin in the rat.

scientific article published in August 1987

Central effects of atrial natriuretic factor on renal salt excretion ⬇️

scientific article published on August 1, 1991

Central effects of somatostatin: pressor response, AVP release, and sympathoinhibition

scientific article published on September 1989

Central noradrenergic pathways are not involved in the pressor response to intracerebroventricular substance P.

scientific article published on September 1988

Characterization of new PPARgamma agonists: analysis of telmisartan's structural components

scientific article published on March 2009

Characterization of new PPARgamma agonists: benzimidazole derivatives - the importance of position 2.

scientific article

Characterization of new PPARgamma agonists: benzimidazole derivatives-importance of positions 5 and 6, and computational studies on the binding mode

scientific article published on 3 July 2010

Chronic pretreatment with candesartan improves recovery from focal cerebral ischaemia in rats ⬇️

scientific article published on November 1, 2003

Chronic treatment with losartan results in sufficient serum levels of the metabolite EXP3179 for PPARgamma activation

scientific article published on 17 August 2009

Cleaved high molecular weight kininogen, a novel factor in the regulation of matrix metalloproteinases in vascular smooth muscle cells

scientific article published on 12 August 2009

Combination therapy of hypertension. Various action principles--advantages of fixed combination preparations

scientific article

Combined Angiotensin Receptor Modulation in the Management of Cardio-Metabolic Disorders

scientific article

Comparison between single and combined treatment with candesartan and pioglitazone following transient focal ischemia in rat brain

scientific article published on 4 March 2008

Comparison of cardioprotective effects of mibefradil and ramipril in stroke-prone spontaneously hypertensive rats.

scientific article

Comparisons of effects of Hoe-498 and enalapril in isolated guinea pig hearts and rat myocardium

scientific article published in June 1985

Compound 21, a selective agonist of angiotensin AT2 receptors, prevents endothelial inflammation and leukocyte adhesion in vitro and in vivo

scientific article published on 5 January 2015

Compound 21, the first orally active, selective agonist of the angiotensin type 2 receptor (AT2): implications for AT2 receptor research and therapeutic potential

scientific article published on 27 October 2009

Contribution of Bradykinin to the Cardioprotective Action of Angiotensin Converting Enzyme Inhibition in Hypertension and After Myocardial Infarction ⬇️

scientific article published on December 1, 1997

Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors.

scientific article published on March 1995

Converting enzyme inhibition in kinin-deficient brown Norway rats

scientific article published on October 1990

Converting enzyme inhibitors and their effects on the renin-angiotensin system of the blood vessel wall

scientific article published on January 1989

Converting enzyme inhibitors in cardiovascular therapy: current status and future potential

scientific article

Decade in review--hypertension: the past decade in hypertension--facts, hopes, and hypes

scientific article published on 02 September 2014

Differential actions of neuronal and hormonal vasopressin on blood pressure and baroreceptor reflex sensitivity in rats

scientific article published in January 1986

Differential contribution of angiotensinergic and cholinergic receptors in the hypothalamic paraventricular nucleus to osmotically induced AVP release ⬇️

scientific article published on June 1, 1998

Differential effects of angiotensin AT1 and AT2 receptors on the expression, translation and function of the Na+-H+ exchanger and Na+-HCO3- symporter in the rat heart after myocardial infarction

scientific article published in June 2001

Differential effects of central angiotensin II and substance P on sympathetic nerve activity in conscious rats. Implications for cardiovascular adaptation to behavioral responses

scientific article published in April 1985

Differential effects of olmesartan and ramipril on inflammatory response after myocardial infarction in rats

scientific article published in January 2006

Differential modulation of the baroreceptor reflex by brain and plasma vasopressin

scientific article published on June 1986

Differential regulation of beta-endorphin in the anterior pituitary, intermediate lobe, hypothalamus and brain stem

scientific article published in January 1983

Differential regulation of thrombospondin-1 and fibronectin by angiotensin II receptor subtypes in cultured endothelial cells

scientific article published in September 2001

Differential therapy of hypertension becomes more specific. Interview by Dr. R.-G. Sommer

scientific article published on August 30, 1997

Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB.

scientific article

Direct angiotensin II type 2 receptor stimulation in Nω-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling

scientific article published on 3 January 2012

Direct angiotensin type 2 receptor (AT2R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice

scientific article published in January 2015

Direct stimulation of angiotensin II type 2 receptor enhances spatial memory

scientific article

Dissociation between in vivo and in vitro measurements of converting enzyme activity after chronic oral treatment with captopril in rats ⬇️

scientific article published on April 21, 1982

Distinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses

scientific article

Distribution of angiotensin II receptor subtypes in rat brain nuclei ⬇️

scientific article published on October 28, 1991

Distribution of neurophysins in rat brain: radioimmunological measurement and characterization

scientific article published in June 1982

Does the AT2-receptor mediate anti-atherosclerotic actions?

scientific article published in August 2005

Effect of chronic volume overload on baroreflex control of heart rate and sympathetic nerve activity ⬇️

scientific article published on December 1, 1997

Effect of hemorrhagic shock on the concomitant release of endorphin and enkephalin-like peptides from the pituitary and adrenal gland in the dog.

scientific article published in January 1982

Effect of high calcium diet on magnesium, catecholamines, and blood pressure of stroke-prone spontaneously hypertensive rats

scientific article

Effect of high-dose valsartan on inflammatory and lipid parameters in patients with Type 2 diabetes and hypertension

scientific article published in September 2010

Effect of sodium chloride and sodium bicarbonate on blood pressure in stroke-prone spontaneously hypertensive rats

scientific article

Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioral responses to stress

scientific article published in January 1997

Effect of urapidil, clonidine, and prazosin on sympathetic tone in conscious rats

scientific article published on April 1986

Effective treatment of hypertension by AT(1) receptor antagonism: the past and future of telmisartan

scientific article published on September 2006

Effects of Angiotensin-Converting Enzyme Inhibition and Angiotensin II AT1 Receptor Antagonism on Cardiac Parameters in Left Ventricular Hypertrophy ⬇️

scientific article published on August 4, 1997

Effects of aliskiren on stroke in rats expressing human renin and angiotensinogen genes

scientific article (publication date: 29 November 2010)

Effects of converting enzyme inhibitors: ramipril and enalapril on peptide action and sympathetic neurotransmission in the isolated heart

scientific article published in July 1985

Effects of endothelin ETA receptor blocker LU 135252 on cardiac remodeling and survival in a hypertensive rat model of chronic heart failure.

scientific article published in November 2006

Effects of intravenous AVP on cardiac output, mesenteric hemodynamics, and splanchnic nerve activity.

scientific article

Effects of nonpersistence with medication on outcomes in high-risk patients with cardiovascular disease

scientific article published on 24 June 2013

Effects of orally applied candesartan cilexetil on central responses to angiotensin II in conscious rats

scientific article

Effects of systemic treatment with irbesartan and losartan on central responses to angiotensin II in conscious, normotensive rats

scientific article published in February 1999

Emerging drugs which target the renin-angiotensin-aldosterone system

scientific article published on 12 September 2011

Endogenous tissue renin-angiotensin systems. From molecular biology to therapy

scientific article published on March 1988

Endothelial dysfunction and its role in diabetic vascular disease

scientific article published on September 2006

Endothelial dysfunction plays a key role in increasing cardiovascular risk in type 2 diabetes: the Hoorn study

scientific article published on 15 September 2014

Estrogen receptor alpha supports cardiomyocytes indirectly through post-infarct cardiac c-kit+ cells

scientific article published on 31 March 2009

Ethanol-induced downregulation of the angiotensin AT2 receptor in murine fibroblasts is mediated by PARP-1.

scientific article published on 18 June 2010

Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS.

scientific article published in May 2017

Evidence for the presence of enkephalins in the heart

scientific article

Excess cardiovascular risk in diabetic women: a case for intensive treatment

scientific article published on June 2015

Experimental evidence for effects of ramipril on cardiac and vascular hypertrophy beyond blood pressure reduction

scientific article published on February 1, 1995

Free and Conjugated Catecholamines in Human Hypertension ⬇️

scientific article published on December 1, 1978

Free and Conjugated Plasma and Urinary Dopamine in Human Hypertension* ⬇️

scientific article published on March 1, 1979

From tissue angiotensin converting enzyme inhibition to antihypertensive effect

scientific article published on March 1991

Functional, biochemical, and molecular investigations of renal kallikrein-kinin system in diabetic rats

scientific article published in December 1999

Genetic kininogen deficiency contributes to aortic aneurysm formation but not to atherosclerosis

scientific article

Growth or antigrowth: angiotensin and the endothelium

scientific article published on December 1995

HYDRA: possible determinants of unsatisfactory hypertension control in German primary care patients

scientific article

High prevalence and poor control of hypertension in primary care: cross-sectional study

scientific article published in March 2004

Identification of a zinc finger homoeodomain enhancer protein after AT(2) receptor stimulation by differential mRNA display

scientific article published in February 2002

Identification of noncytotoxic and IL-10-producing CD8+AT2R+ T cell population in response to ischemic heart injury

scientific article published on 8 October 2010

Identification of regulated genes in rat heart after myocardial infarction by means of differential mRNA display

scientific article published in January 2000

Impact of AT2-receptor stimulation on vascular biology, kidney function, and blood pressure

scientific article

Impact of sex on cardiovascular outcome in patients at high cardiovascular risk: analysis of the Telmisartan Randomized Assessment Study in ACE-Intolerant Subjects With Cardiovascular Disease (TRANSCEND) and the Ongoing Telmisartan Alone and in Comb

scientific article published on 24 July 2012

Impact of telmisartan on cardiovascular outcome in hypertensive patients at high risk: a Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease subanalysis

scientific article published in June 2014

Impact of the AT(2) receptor agonist C21 on blood pressure and beyond

scientific article published on October 2012

In vivo activity of purified mouse brain renin

scientific article published in August 1981

Inflammation in the genesis of hypertension and its complications the role of angiotensin II

article published in 2007

Inhibition of tissue angiotensin converting enzyme activity prevents malignant hypertension in TGR(mREN2)27 ⬇️

scientific article published on May 1, 1998

Introduction: Reducing cardiovascular risk: ONTARGET--a new standard in cardiovascular protection.

scientific article published in July 2009

Involvement of adrenergic and angiotensinergic receptors in the paraventricular nucleus in the angiotensin II-induced vasopressin release ⬇️

scientific article published on December 1, 1992

Involvement of adrenoceptors in the angiotensin II-induced expression of inducible transcription factors in the rat forebrain and hypothalamus

scientific article published in February 2002

Is arterial media hypertrophy in spontaneously hypertensive rats a consequence of or a cause for hypertension?

scientific article

Is tissue converting enzyme inhibition a determinant of the antihypertensive efficacy of converting enzyme inhibitors? Studies with the two different compounds, Hoe498 and MK421, in spontaneously hypertensive rats.

scientific article published in September 1984

Key advances in antihypertensive treatment

scientific article published on 20 March 2012

Kinin contribution to chronic antihypertensive actions of ACE-inhibitors in hypertensive rats

scientific article published on January 1, 1992

Lessons from ALLHAT. Are low budget diuretics first line therapy in hypertension?

scientific article

Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan

scientific article published on 9 January 2008

Localization of renin (EC 3.4.23) and converting enzyme (EC 3.4.15.1) in nerve endings of rat brain

scientific article published in May 1985

Localization of the substance P-induced cardiovascular responses in the rat hypothalamus ⬇️

scientific article published on August 30, 1991

Mast cell-derived TNF-α and histamine modify IL-6 and IL-8 expression and release from cutaneous tumor cells

scientific article

Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma

scientific article

Microalbuminuria in patients with hypertension and cardiovascular comorbidity, REAL observational study of treatment with Irbesartan/HCTZ

scientific article published in June 2006

Moderate Correlations of in vitro versus in vivo Pharmacokinetics Questioning the Need of Early Microsomal Stability Testing ⬇️

scientific article published on October 4, 2012

Modulation of autonomic nervous system adjustments to heat stress by central ANG II receptor antagonism

scientific article

Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity

scientific article published on December 2005

Myocardial expression of rat bradykinin receptors and two tissue kallikrein genes in experimental diabetes

scientific article published in October 1999

NaCl injections in brain induce natriuresis and blood pressure responses sensitive to ANG II AT1 receptors ⬇️

scientific article published on August 1, 1995

Natriuretic action of central angiotensin II in conscious rats

scientific article published on May 1989

New therapeutic pathways in the RAS.

scientific article published on December 2012

Non-peptide AT2-receptor agonists

scientific article published on 15 December 2010

Novel therapeutic targets for hypertension

scientific article published on 22 June 2010

Novel therapy approach in primary stroke prevention: simultaneous inhibition of endothelin converting enzyme and neutral endopeptidase in spontaneously hypertensive, stroke-prone rats improves survival

scientific article

ORIGINAL ARTICLE: Renal Outcome in Equipotent Antihypertensive Treatment with Telmisartan, Ramipril and in Combination in SHR-SP Rats

scientific article published in 2013

Opioid peptides and blood pressure regulation

scientific article published in January 1982

Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study

scientific article published on 2 April 2007

Oxytocin Pathways Mediate the Cardiovascular and Behavioral Responses to Substance P in the Rat Brain ⬇️

scientific article published on January 1, 1998

PLZF and the (pro)renin receptor

scientific article published on 12 March 2008

PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice

scientific article published on 18 October 2010

PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin

scientific article published on 6 June 2005

Pathophysiologic and therapeutic importance of tissue ACE: a consensus report

scientific article

Pathophysiological and clinical implications of AT(1)/AT(2) angiotensin II receptors in heart failure and coronary and renal failure

scientific article published in January 2002

Pathophysiology of essential hypertension. Recent findings (author's transl)

scientific article published on November 20, 1981

Patient-doctor interactions in hypertension

scientific article published in January 1995

Patterns of antihypertensive drug utilization in primary care

article published in 2004

Peptidergic and catecholaminergic mechanisms in central blood pressure control.

scientific article published on January 1980

Peptidergic systems: effects on blood vessels

scientific article

Peripherally applied candesartan inhibits central responses to angiotensin II in conscious rats

scientific article

Persistent tissue converting enzyme inhibition following chronic treatment with Hoe498 and MK421 in spontaneously hypertensive rats

scientific article published on January 1985

Perspective: A tale of two receptors.

scientific article published in January 2013

Pharmacological interferences with the renin-angiotensin system.

scientific article

Pharmacology of Converting Enzyme Inhibitors: New Aspects ⬇️

scientific article published on January 1, 1983

Physiological and pharmacological implications of AT1 versus AT2 receptors ⬇️

scientific article published on September 1, 1998

Plasma renin and cardiovascular risk: what is the evidence for an association?

scientific article published on 30 April 2013

Poly(ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates angiotensin AT2 receptor (AT2R) and AT2R binding protein (ATBP) genes

scientific article published on 19 March 2009

Post-transplantation hypertension in recipients of renal grafts from hypertensive donor rats

scientific article published in December 1991

Prevention and intervention studies with telmisartan, ramipril and their combination in different rat stroke models

scientific article (publication date: 2011)

Prevention of Coronary Artery Disease: Recent Advances in the Management of Hypertension ⬇️

scientific article published on March 1, 2013

Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren

scientific article published in September 2008

Protective arms of the renin-angiotensin-system in neurological disease

scientific article published on August 2013

Quantitative real-time RT-PCR data analysis: current concepts and the novel "gene expression's CT difference" formula

scientific article

RAS blockade with ARB and ACE inhibitors: current perspective on rationale and patient selection

scientific article published on 03 May 2008

Receptor autoradiographical evidence of a preferential reduction of binding sites for atrial natriuretic factor in renal papilla of the spontaneously hypertensive rat

scientific article published on 01 September 1988

Receptors and their classification: focus on angiotensin II and the AT2 receptor ⬇️

scientific article published on May 1, 1998

Recognition and management of overweight and obesity in primary care in Germany

article

Reduction (TELMAR) as assessed by magnetic resonance imaging in patients with mild-to-moderate hypertension--a prospective, randomised, double-blind comparison of telmisartan with metoprolol over a period of six months rationale and study design

scientific article published in December 2003

Regulation of peroxisome proliferator-activated receptor gamma activity by losartan metabolites

scientific article published on 19 December 2005

Relations between pharmacokinetics and effectiveness of ACE inhibitors

scientific article

Release and regulation of atrial natriuretic peptide (ANP).

scientific article published on May 1987

Renal expression of two rat kallikrein genes under diabetic conditions ⬇️

scientific article published on December 1, 1997

Renal outcome in equipotent antihypertensive treatment with telmisartan, ramipril and in combination in SHR-SP rats

scientific article published on January 1, 2012

Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies

scientific article

Renin-dependent water intake in hypovolemia

scientific article published in October 1988

Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats

scientific article published in June 1992

Repression of c-fos and c-jun gene expression is not part of AT2 receptor coupled signal transduction

scientific article published in March 1998

Role of bradykinin in chronic antihypertensive actions of ramipril in different hypertension models

scientific article published on January 1, 1992

Role of bradykinin in the antihypertensive and cardioprotective actions of converting enzyme inhibitors

scientific article published on July 1995

Role of brain angiotensin in cardiovascular regulation

scientific article published on January 1, 1992

Role of dopamine in the regulation of arterial pressure and sodium excretion. Physiopathological and clinical implications

scientific article published on April 1, 1977

Role of the kidney in primary hypertension: a renal transplantation study in rats

scientific article published on March 1990

Role of the kidney in the pathogenesis of primary hypertension

scientific article published on January 1990

SA446, a new orally active converting enzyme inhibitor: Antihypertensive action and comparison with captopril in stroke-prone spontaneously hypertensive rats ⬇️

scientific article published on March 26, 1982

Selective activation of the converting enzyme inhibitor MK 421 and comparison of its active diacid form with captopril in different tissues of the rat ⬇️

scientific article published on October 1, 1982

Sensitivity of hypothalamic paraventricular nucleus to C- and N-terminal angiotensin fragments: vasopressin release and drinking

scientific article published on April 1, 1998

Sensitization to pressor effects by repeated central injections of vasopressin in conscious rats

scientific article

Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability.

scientific article

Sex-specific influence of angiotensin type 2 receptor stimulation on renal function: a novel therapeutic target for hypertension

scientific article published on 12 December 2011

Signal transduction of the (pro)renin receptor as a novel therapeutic target for preventing end-organ damage

scientific article published on 11 December 2009

Significance of timing of angiotensin AT1 receptor blockade in rats with myocardial infarction-induced heart failure

scientific article

Stimulation of the Angiotensin II AT2 Receptor is Anti-inflammatory in Human Lipopolysaccharide-Activated Monocytic Cells

scientific article

Substance P induces a cardiovascular defense reaction in the rat: pharmacological characterization

scientific article

Substrate metabolism, hormone interaction, and angiotensin-converting enzyme inhibitors in left ventricular hypertrophy

scientific article published on January 1996

Sympathetic activation following central vasopressin receptor stimulation in conscious rats

scientific article published on December 1, 1984

Sympathetic denervation blocks blood pressure elevation in episodic hypoxia

scientific article published on November 1, 1992

Systolic blood pressure variation and mean heart rate is associated with cognitive dysfunction in patients with high cardiovascular risk

scientific article published on 12 January 2015

Telmisartan and hydrochlorothiazide combination therapy for the treatment of hypertension

scientific article published on April 2010

Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation

scientific article

The (pro)renin receptor ((P)RR) can act as a repressor of Wnt signalling

scientific article

The (pro)renin receptor mediates constitutive PLZF-independent pro-proliferative effects which are inhibited by bafilomycin but not genistein

scientific article published on 14 January 2014

The PHARAO study: prevention of hypertension with the angiotensin-converting enzyme inhibitor ramipril in patients with high-normal blood pressure: a prospective, randomized, controlled prevention trial of the German Hypertension League

scientific article published in July 2008

The angiotensin AT2 receptor in inflammation

scientific article published on March 2010

The angiotensin AT2 receptor in left ventricular hypertrophy

scientific article published on September 2010

The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells

scientific article published on February 1995

The angiotensin II AT2 receptor inhibits proliferation and promotes differentiation in PC12W cells

scientific article published on August 1996

The angiotensin type 2 receptor: variations on an enigmatic theme

scientific article

The beta-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke

scientific article

The brain angiotensin system: subcellular localization and interferences with converting enzyme inhibitors

scientific article published on October 1, 1983

The brain renin angiotensin system in central cardiovascular control.

scientific article

The brain renin--angiotensin system

scientific article published on January 1, 1981

The cardiovascular continuum refined: A hypothesis

scientific article published on October 2010

The cardiovascular effects of oxytocin in conscious male rats

scientific article published in June 1985

The dual role of angiotensin and vasopressin as plasma hormones and neuropeptides in cardiovascular regulation

scientific article published on January 1985

The endothelium and vascular inflammation in diabetes

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