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List of works by Norma Andrews

A Leishmania amazonensis ZIP family iron transporter is essential for parasite replication within macrophage phagolysosomes.

scientific article

A MFS-like plasma membrane transporter required for Leishmania virulence protects the parasites from iron toxicity.

scientific article

A T. cruzi-secreted protein immunologically related to the complement component C9: evidence for membrane pore-forming activity at low pH.

scientific article published on June 1990

A Trypanosomatid Iron Transporter that Regulates Mitochondrial Function Is Required for Leishmania amazonensis Virulence

scientific article

A cytosolic serine endopeptidase from Trypanosoma cruzi is required for the generation of Ca2+ signaling in mammalian cells

scientific article

A process for controlling intracellular bacterial infections induced by membrane injury

scientific article published on June 2004

A role for synaptotagmin VII-regulated exocytosis of lysosomes in neurite outgrowth from primary sympathetic neurons

scientific article published on 01 April 2006

A trypanosome-soluble factor induces IP3 formation, intracellular Ca2+ mobilization and microfilament rearrangement in host cells

scientific article

Above the fray: Surface remodeling by secreted lysosomal enzymes leads to endocytosis-mediated plasma membrane repair

scientific article

Amastigotes of Trypanosoma cruzi sustain an infective cycle in mammalian cells

scientific article

Approaches for plasma membrane wounding and assessment of lysosome-mediated repair responses.

scientific article published on 14 January 2015

Ascorbate-Dependent Peroxidase (APX) from Leishmania amazonensis Is a Reactive Oxygen Species-Induced Essential Enzyme That Regulates Virulence

scientific article published on 18 November 2019

Ca2+ and synaptotagmin VII-dependent delivery of lysosomal membrane to nascent phagosomes

scientific article

Caveolae internalization repairs wounded cells and muscle fibers.

scientific article published on 17 September 2013

Cell surface antigens of Trypanosoma cruzi: possible correlation with the interiorization process in mammalian cells.

scientific article published in August 1982

Characterization of a 21kDa protein from Trypanosoma cruzi associated with mammalian cell invasion.

scientific article published in April 2009

Cholesterol access aids pathogen spread

scientific article published on 01 July 2020

Control of parasitophorous vacuole expansion by LYST/Beige restricts the intracellular growth of Leishmania amazonensis

scientific article

Damage control: cellular mechanisms of plasma membrane repair

scientific article

Defective lysosomal exocytosis and plasma membrane repair in Chediak-Higashi/beige cells.

scholarly article

Defects in sarcolemma repair and skeletal muscle function after injury in a mouse model of Niemann-Pick type A/B disease

scientific article published on 05 January 2019

Desialylation of lysosomal membrane glycoproteins by Trypanosoma cruzi: a role for the surface neuraminidase in facilitating parasite entry into the host cell cytoplasm.

scientific article

Detection of Lysosomal Exocytosis by Surface Exposure of Lamp1 Luminal Epitopes.

scientific article published in January 2017

Differential role of the Ca(2+) sensor synaptotagmin VII in macrophages and dendritic cells

scientific article published on 20 January 2009

Don't bother to knock--the cell invasion strategy of Trypanosoma cruzi

scientific article

Dual role of signaling pathways leading to Ca(2+) and cyclic AMP elevation in host cell invasion by Trypanosoma cruzi ⬇️

scientific article published on December 2000

ESCRT: nipping the wound in the bud?

scientific article published on 20 June 2014

Endophilin-A2 dependent tubular endocytosis promotes plasma membrane repair and parasite invasion

scientific article published on 22 October 2020

Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair

scientific article

Expression and function of synaptotagmin VII in CTLs

scientific article

Expression of the mammalian calcium signaling response to Trypanosoma cruzi in Xenopus laevis oocytes ⬇️

scientific article published on April 1, 1998

Expression, purification and preliminary crystallographic analysis of oligopeptidase B from Trypanosoma brucei

scientific article published on 25 July 2006

Extracellular amastigotes of Trypanosoma cruzi are potent inducers of phagocytosis in mammalian cells

scientific article published on 9 January 2013

Functional characterization of LIT1, the Leishmania amazonensis ferrous iron transporter

scientific article published on 16 December 2009

Gaucher disease iPSC-derived osteoblasts have developmental and lysosomal defects that impair bone matrix deposition.

scientific article published on 2 January 2018

Heme uptake by Leishmania amazonensis is mediated by the transmembrane protein LHR1.

scientific article

Heme uptake mediated by LHR1 is essential for Leishmania amazonensis virulence

scientific article published on 22 July 2013

Homotypic fusion between aggregated lysosomes triggered by elevated [Ca2+]i in fibroblasts ⬇️

scientific article published on 01 September 1997

Host cell invasion by Trypanosoma cruzi: a unique strategy that promotes persistence ⬇️

scientific article published on 13 March 2012

Host cell invasion by trypanosomes requires lysosomes and microtubule/kinesin-mediated transport

scientific article

How Do Bone Cells Secrete Proteins?

scientific article published on 01 January 2010

IRONy OF FATE: role of iron-mediated ROS in Leishmania differentiation

scientific article published on 12 August 2013

Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis

scientific article

Identification of the reactive cysteine residues in oligopeptidase B from Trypanosoma brucei

scientific article

Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient mice

scientific journal article

Intracellular iron availability modulates the requirement for Leishmania Iron Regulator 1 (LIR1) during macrophage infections

scientific article published on 22 March 2019

Iron acquisition within host cells and the pathogenicity of Leishmania

scientific article published on 9 December 2007

Iron uptake controls the generation of Leishmania infective forms through regulation of ROS levels

scientific article published on 4 February 2013

LFR1 ferric iron reductase of Leishmania amazonensis is essential for the generation of infective parasite forms

scientific article

Leishmania amazonensis Rab7 promotes toxicity of the amino acid ester Leu-OMe in amastigote megasomes

scientific article published in December 2003

Leishmania amazonensis ferric iron reductase (LFR1) is a bifunctional enzyme: Unveiling a NADPH oxidase activity

scientific article published on 22 August 2019

Leishmania infection inhibits macrophage motility by altering F-actin dynamics and the expression of adhesion complex proteins

scientific article published on 18 September 2016

Leishmania promotes its own virulence by inducing expression of the host immune inhibitory ligand CD200

scientific article

Leishmania-mediated inhibition of iron export promotes parasite replication in macrophages.

scientific article published on 30 January 2014

Lipid raft-dependent plasma membrane repair interferes with the activation of B lymphocytes

scientific article

Live imaging assay for assessing the roles of Ca2+ and sphingomyelinase in the repair of pore-forming toxin wounds

scientific article published on 25 August 2013

Living dangerously: how Trypanosoma cruzi uses lysosomes to get inside host cells, and then escapes into the cytoplasm

scientific article published on January 1, 1993

Lysosomal fusion is essential for the retention of Trypanosoma cruzi inside host cells.

scientific article

Lysosomes and the plasma membrane: trypanosomes reveal a secret relationship

scientific article

Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cells

scientific article

Mapping of surface glycoproteins of Trypanosoma cruzi by two-dimensional electrophoresis. A correlation with the cell invasion capacity

scientific article published on 01 May 1984

Membrane cholesterol removal changes mechanical properties of cells and induces secretion of a specific pool of lysosomes

scientific article

Membrane proximal lysosomes are the major vesicles responsible for calcium-dependent exocytosis in nonsecretory cells

scientific article

Membrane repair and immunological danger.

scientific article

Membrane resealing: synaptotagmin VII keeps running the show

scientific article

Oligopeptidase B from Trypanosoma brucei, a new member of an emerging subgroup of serine oligopeptidases.

scientific article

Oligopeptidase B-dependent signaling mediates host cell invasion by Trypanosoma cruzi ⬇️

scientific article

Opsonization modulates Rac-1 activation during cell entry by Leishmania amazonensis

scientific article

Oxidative stress and intracellular infections: more iron to the fire ⬇️

scientific article published on June 25, 2012

PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.

scientific article published on 20 October 2016

Palmitoylation-dependent association with CD63 targets the Ca2+ sensor synaptotagmin VII to lysosomes

scientific journal article

Pathways of iron acquisition and utilization in Leishmania.

scientific article published on 17 August 2013

Phagolysosomal escape by intracellular pathogens.

scientific article published in December 1991

Plasma Membrane Repair Is Regulated Extracellularly by Proteases Released from Lysosomes.

scientific article

Plasma membrane repair

scientific article published on 01 April 2018

Presence of antibodies to the major surface glycoprotein of Trypanosoma cruzi amastigotes in sera from Chagasic patients

Quantification of Intracellular Growth Inside Macrophages is a Fast and Reliable Method for Assessing the Virulence of Leishmania Parasites.

scientific article published on 16 March 2018

ROS regulate differentiation of visceralizing Leishmania species into the virulent amastigote form

scientific article published on 06 November 2018

Regulation of insulin secretion and GLUT4 trafficking by the calcium sensor synaptotagmin VII.

scientific article

Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis

scientific article

Resisting attack by repairing the damage

scientific article published on 22 April 2022

Role for sialic acid in the formation of tight lysosome-derived vacuoles during Trypanosoma cruzi invasion

scientific article

Role of host lysosomal associated membrane protein (LAMP) in Trypanosoma cruzi invasion and intracellular development ⬇️

scientific article

Secretion by Trypanosoma cruzi of a hemolysin active at low pH

scientific article published on 01 March 1989

Solving the secretory acid sphingomyelinase puzzle: Insights from lysosome-mediated parasite invasion and plasma membrane repair

scientific article published on 10 June 2019

Spermatogenesis in Trichosia pubescens (Diptera:Sciaridae)

scientific article published on April 1, 1979

Stage-specific surface antigens during the morphogenesis of Trypanosoma cruzi: developmentally regulated expression of a glycosyl-phosphatidylinositol anchored glycoprotein of amastigotes

scientific article published on 01 November 1988

Stage-specific surface antigens expressed during the morphogenesis of vertebrate forms of Trypanosoma cruzi

scientific article published in December 1987

Subsite specificity (S3, S2, S1', S2' and S3') of oligopeptidase B from Trypanosoma cruzi and Trypanosoma brucei using fluorescent quenched peptides: comparative study and identification of specific carboxypeptidase activity

scientific article published on August 2003

Substrate recognition properties of oligopeptidase B from Salmonella enterica serovar Typhimurium

scientific article

Synaptotagmin VII regulates bone remodeling by modulating osteoclast and osteoblast secretion

scientific journal article

Synaptotagmin VII restricts fusion pore expansion during lysosomal exocytosis

scientific article

Synaptotagmin-mediated vesicle fusion regulates cell migration

scientific article

The Exocytosis-regulatory protein synaptotagmin VII mediates cell invasion by Trypanosoma cruzi ⬇️

scientific article

The Heme Transport Capacity of LHR1 Determines the Extent of Virulence in Leishmania amazonensis.

scientific article published on 22 May 2015

The Trypanosoma cruzi-host-cell interplay: location, invasion, retention

scientific article

The exit of Trypanosoma cruzi from the phagosome is inhibited by raising the pH of acidic compartments

scientific article

The exocyst is required for trypanosome invasion and the repair of mechanical plasma membrane wounds. ⬇️

scientific article

The iron-dependent mitochondrial superoxide dismutase SODA promotes Leishmania virulence.

scientific article published on 26 May 2017

The plasma membrane repair shop: Fixing the damage

scientific article published on 01 September 2015

The small chemical vacuolin-1 alters the morphology of lysosomes without inhibiting Ca2+-regulated exocytosis

scientific article

There's more to life than neurotransmission: the regulation of exocytosis by synaptotagmin VII.

scientific article

Toxin pores endocytosed during plasma membrane repair traffic into the lumen of MVBs for degradation.

scientific article published on 24 January 2012

Trypanosoma cruzi invade a mammalian epithelial cell in a polarized manner

scientific article published in October 1988

Trypanosoma cruzi invades synaptotagmin VII-deficient cells by a PI-3 kinase independent pathway.

scientific article published in May 2005

Trypanosoma cruzi subverts the sphingomyelinase-mediated plasma membrane repair pathway for cell invasion ⬇️

scientific article

Trypanosoma cruzi trypomastigotes induce cytoskeleton modifications during HeLa cell invasion.

scientific article

Trypanosoma cruzi: mechanisms of cell-invasion and intracellular survival

scientific article published in 1988

Trypanosoma cruzi: protection in mice immunized with 8-methoxypsoralen-inactivated trypomastigotes

scientific article

Trypanosomatid selenophosphate synthetase structure, function and interaction with selenocysteine lyase

scientific article published on 05 October 2020

Two-way traffic on the road to plasma membrane repair

scientific article published on 09 October 2008

Why do so many surface proteins of trypanosomatids have GPI-anchors?

scientific article published on September 1991

cAMP regulates Ca2+-dependent exocytosis of lysosomes and lysosome-mediated cell invasion by trypanosomes

scientific article published on 01 June 1999

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