Search filters

List of works by Irene Esposito

5' Triphosphorylated small interfering RNAs control replication of hepatitis B virus and induce an interferon response in human liver cells and mice

scientific article published on 13 May 2011

A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas

scientific article

A common genetic variation of melanoma inhibitory activity-2 labels a subtype of pancreatic adenocarcinoma with high endoplasmic reticulum stress levels

scientific article published on 6 February 2015

A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer

scientific article published on 8 December 2014

A new Fgf10 mutation in the mouse leads to atrophy of the harderian gland and slit-eye phenotype in heterozygotes: a novel model for dry-eye disease?

scientific article published on 30 April 2009

A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model

article

A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling

scientific article published on 19 January 2015

Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells

scientific article published on 19 May 2016

Aloxe3 knockout mice reveal a function of epidermal lipoxygenase-3 as hepoxilin synthase and its pivotal role in barrier formation

scientific article

Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity

scientific article

Association between gallstone-evoked pain, inflammation and proliferation of nerves in the gallbladder: a possible explanation for clinical differences

scientific article published in July 2007

Atypical flat lesions derive from pancreatic acinar cells

scientific article published on 25 April 2017

Autoimmune pancreatitis associated with a large pancreatic pseudocyst

scientific article published on September 2006

Autoimmune pancreatitis complicated by carcinoma of the pancreatobiliary system: a case report and review of the literature

scientific article published on January 2011

Autoimmune pancreatocholangitis, non-autoimmune pancreatitis and primary sclerosing cholangitis: a comparative morphological and immunological analysis

scientific article

BCL3 Reduces the Sterile Inflammatory Response in Pancreatic and Biliary Tissues

scientific article published on 22 October 2015

Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers

scientific article published on 25 April 2016

Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma

scientific article published on May 2009

Chronic pancreatitis

scientific article published on 7 September 2017

Claudin 18.2 is a target for IMAB362 antibody in pancreatic neoplasms

scientific article

Clinical features and relapse rates after surgery in type 1 autoimmune pancreatitis differ from type 2: a study of 114 surgically treated European patients

scientific article published on 19 March 2012

Co-clinical Assessment of Tumor Cellularity in Pancreatic Cancer

scientific article published on 23 September 2016

Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma

Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

scientific article published on 21 September 2015

Consensus transcriptome signature of perineural invasion in pancreatic carcinoma

scientific article

DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma

scientific article published on 30 November 2012

Definition of microscopic tumor clearance (r0) in pancreatic cancer resections

scientific article

Diet intervention reduces uptake of αvβ3 integrin-targeted PET tracer 18F-galacto-RGD in mouse atherosclerotic plaques

article by Antti Saraste et al published 20 April 2012 in Journal of Nuclear Cardiology

Differential effects of genes of the Rb1 signalling pathway on osteosarcoma incidence and latency in alpha-particle irradiated mice

scientific article published on 10 November 2010

Differential localization and activation of mast cells in chronic pancreatitis of different etiologies

Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy

scientific article

Early undifferentiated pancreatic carcinoma with osteoclastlike giant cells: direct evidence for ductal evolution

article

Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.

scientific article published on 2 May 2014

Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models

scientific article published on February 1, 2013

Erratum to: New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis.

scientific article published on 7 August 2014

Erratum: Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical and molecular analysis of 20 cases

scholarly article published in Modern Pathology

Evaluation and management of a patient with a bladder mass of uncertain etiology

scientific article published in September 2008

Evaluation of alphavbeta3 integrin-targeted positron emission tomography tracer 18F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice

scientific article published on 13 May 2009

Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial

scientific article published on 2 August 2014

Expression analysis of PMP22/Gas3 in premalignant and malignant pancreatic lesions

scientific article published on July 2005

Expression of L1CAM, COX-2, EGFR, c-KIT and Her2/neu in anaplastic pancreatic cancer: putative therapeutic targets?

scientific article published in March 2010

Expression of the Shwachman-Bodian-Diamond syndrome (SBDS) protein in human pancreatic cancer and chronic pancreatitis

scientific article

Expression of the costimulatory molecule B7-H3 is associated with prolonged survival in human pancreatic cancer

scientific article

Expression pattern and functional relevance of epidermal growth factor receptor and cyclooxygenase-2: novel chemotherapeutic targets in pancreatic endocrine tumors?

scientific article

Extended RAS analysis and correlation with overall survival in advanced pancreatic cancer

scientific article published on 27 April 2017

Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice

scientific article published on 8 August 2012

G-Protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1

scientific article

Glucagon/insulin ratio as a potential biomarker for pancreatic cancer in patients with new-onset diabetes mellitus.

scientific article published on 13 August 2009

Glutamate increases pancreatic cancer cell invasion and migration via AMPA receptor activation and Kras-MAPK signaling

scientific article published on 7 April 2011

Hydroxysteroid (17β) dehydrogenase 13 deficiency triggers hepatic steatosis and inflammation in mice

scientific article published on 31 January 2018

Hypothetical Progression Model of Pancreatic Cancer With Origin in the Centroacinar-Acinar Compartment

article

Hypoxia-induced endoplasmic reticulum stress characterizes a necrotic phenotype of pancreatic cancer

scientific article published on 5 October 2015

Identification of differentially expressed proteins in triple-negative breast carcinomas using DIGE and mass spectrometry

scientific article

Identification of malignancy factors by analyzing cystic tumors of the pancreas

scientific article published on 12 December 2008

IgG4-associated cholangitis with cholangiocarcinoma

scientific article

Impaired islet turnover in human donor pancreata with aging

scientific article published on 12 November 2008

In Vivo PET Imaging of the Cancer Integrin αvβ6 Using 68Ga-Labeled Cyclic RGD Nonapeptides

scientific article published on 15 December 2016

In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging

scientific article

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

scientific article

Increased expression of Nodal correlates with reduced patient survival in pancreatic cancer

scientific article

Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer

scientific article

Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.

scientific article published on 2 April 2014

Intraductal Tubulopapillary Neoplasm of the Pancreas: A Clinicopathologic and Immunohistochemical Analysis of 33 Cases

scientific article

Intraductal neoplasms of the pancreas

scientific article published on 02 September 2014

Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways

scientific article published on 5 July 2013

Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical, and molecular analysis of 20 cases

scientific article published on 26 June 2015

Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical, and molecular analysis of 20 cases

Isolation of circulating tumor cells from pancreatic cancer by automated filtration

scientific article

K-Ras and cyclooxygenase-2 coactivation augments intraductal papillary mucinous neoplasm and Notch1 mimicking human pancreas lesions

scientific article

Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis

scientific article

Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease

scientific article

Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas

scientific article (publication date: April 2005)

Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis

scientific article published in June 2005

Loss of Periostin Results in Impaired Regeneration and Pancreatic Atrophy after Cerulein-Induced Pancreatitis

scientific article published on 27 November 2015

MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer

scientific article published in 2012

Mesenchymal Wt1 positive stellate cells represent a minor source of the fibrotic response in pancreatitis

scholarly article by Ivonne Regel et al published June 2015 in Pancreatology

MicroRNA-196a and -196b as Potential Biomarkers for the Early Detection of Familial Pancreatic Cancer

scientific article published on 21 June 2014

Microcystic tubulopapillary carcinoma of the pancreas: a new tumor entity?

scientific article published on 11 March 2004

Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 ( 416insG ) mice

scientific article published on 22 December 2009

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia

scientific journal article

Moesin-dependent cytoskeleton remodelling is associated with an anaplastic phenotype of pancreatic cancer

scientific article published on 11 May 2009

Molecular and immunohistochemical subtyping of pancreatic ductal adenocarcinoma (PDAC): A step towards personalized treatment and individual prognosis

scholarly article by Anna Melissa Schlitter et al published May 2013 in Pancreatology

Molecular, morphological and survival analysis of 177 resected pancreatic ductal adenocarcinomas (PDACs): Identification of prognostic subtypes

scientific article published on February 2017

MondoA is highly overexpressed in acute lymphoblastic leukemia cells and modulates their metabolism, differentiation and survival

scientific article published on 29 June 2012

Most Pancreatic Cancer Resections are R1 Resections

Mouse phenotyping

scientific article

Multimodal molecular imaging of integrin αvβ3 for in vivo detection of pancreatic cancer

scientific article published on 18 February 2014

New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis

scientific article

Oligoclonal T-cell populations in an inflammatory pseudotumor of the pancreas possibly related to autoimmune pancreatitis: an immunohistochemical and molecular analysis.

scientific article

Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues

scientific article published on 17 January 2012

Outcomes of resections for pancreatic adenocarcinoma with suspected venous involvement: a single center experience

scientific article published on 22 August 2015

Overexpressed decorin in pancreatic cancer: potential tumor growth inhibition and attenuation of chemotherapeutic action

scientific article published on July 2004

Overexpression of cellular inhibitor of apoptosis protein 2 is an early event in the progression of pancreatic cancer

scientific article

Pancreas-specific activation of mTOR and loss of p53 induce tumors reminiscent of acinar cell carcinoma

scientific article

Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response

scientific article published on 3 November 2017

Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver

scientific article published on 6 August 2016

Pancreatic Resection for M1 Pancreatic Ductal Adenocarcinoma

Pancreatic cancer microenvironment

scientific article published on August 2007

Pancreatic tumor cells influence the composition of the extracellular matrix

scientific article

Pathobiology of pancreatic cancer: implications on therapy

scientific article

Pathology of pancreatic ductal adenocarcinoma: facts, challenges and future developments

scientific article

Periostin and tumor-stroma interactions in non-small cell lung cancer

scientific article published on 14 September 2016

Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity

scientific article published on 25 January 2007

Perspective of αvβ6-Integrin Imaging for Clinical Management of Pancreatic Carcinoma and Its Precursor Lesions

scientific article

Pigment epithelium-derived factor associates with neuropathy and fibrosis in pancreatic cancer

scientific article published on 11 January 2011

Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells

scientific article published on 22 December 2015

Precancerous Lesions and Carcinoma of the Pancreas

scientific article published on 3 February 2015

Preclinical assesement of survivin and XIAP as prognostic biomarkers and therapeutic targets in gastroenteropancreatic neuroendocrine neoplasia

scientific article published on 26 December 2016

Preinvasive duct-derived neoplasms in pancreas of keratin 5-promoter cyclooxygenase-2 transgenic mice

scientific article

Preoperative acute pancreatitis in periampullary tumors: implications for surgical management

scientific article published on 7 August 2007

Preoperative radiological characterization of hepatic angiomyolipoma using magnetic resonance imaging and contrast-enhanced ultrasonography: a case report

scientific article published on September 26, 2011

R0 Versus R1 Resection Matters after Pancreaticoduodenectomy, and Less after Distal or Total Pancreatectomy for Pancreatic Cancer

scientific article published on 07 July 2017

RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors

scientific article published on 05 August 2016

Reduced expression of the membrane skeleton protein beta1-spectrin (SPTBN1) is associated with worsened prognosis in pancreatic cancer.

scientific article

Renal cancer cell metastasis into the pancreas: a single-center experience and overview of the literature

scientific article

Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice

scientific article

Resectability After First-Line FOLFIRINOX in Initially Unresectable Locally Advanced Pancreatic Cancer: A Single-Center Experience

scientific article

STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors

scientific article

Second-look operation for unresectable pancreatic ductal adenocarcinoma at a high-volume center

scientific article

Secreted frizzled-related protein 1 extrinsically regulates cycling activity and maintenance of hematopoietic stem cells

scientific journal article

Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer

scientific article

Silencing of X-linked inhibitor of apoptosis (XIAP) decreases gemcitabine resistance of pancreatic cancer cells

scientific article published on September 2006

Solid type clear cell carcinoma of the pancreas: differential diagnosis of an unusual case and review of the literature

scientific article published on 24 April 2007

Somatostatin receptor expression related to TP53 and RB1 alterations in pancreatic and extrapancreatic neuroendocrine neoplasms with a Ki67-index above 20.

scientific article published on 6 January 2017

Sorafenib inhibits macrophage-induced growth of hepatoma cells by interference with insulin-like growth factor-1 secretion

scientific article

Spinal muscular atrophy type 1: avoidance of hospitalization by respiratory muscle support

scientific article

Splenic and portal vein thrombosis in pancreatic metastasis from renal cell carcinoma

scientific article published on 17 May 2006

Srgap3⁻/⁻ mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes

scientific article published on 20 July 2012

StellaTUM: current consensus and discussion on pancreatic stellate cell research

scientific article published on 24 November 2011

Structure-Preserving Color Normalization and Sparse Stain Separation for Histological Images

scientific article published on 27 April 2016

Surgery for cystic pancreatic lesions in the post-sendai era: a single institution experience

scientific article

Tenascin-C enhances pancreatic cancer cell growth and motility and affects cell adhesion through activation of the integrin pathway

scientific article

The German Mouse Clinic – Running an Open Access Platform

article

The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma

scientific article published on 17 July 2008

The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma

scientific article

The impact of the activated stroma on pancreatic ductal adenocarcinoma biology and therapy resistance

scientific article published on March 2012

The stem cell factor-c-kit system and mast cells in human pancreatic cancer

scientific article published on November 2002

Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells

scientific article

Transcriptional network governing the angiogenic switch in human pancreatic cancer

scholarly article

Tumor-Stromal Interactions in Invasion and Metastases

scholarly article published 2010

Tumor-suppressor function of SPARC-like protein 1/Hevin in pancreatic cancer

scientific article published in January 2007

Two pediatric cases of multidrug-resistant tuberculosis treated with linezolid and moxifloxacin

scientific article published on 25 October 2010

Yes-associated protein (YAP65) in relation to Smad7 expression in human pancreatic ductal adenocarcinoma

scientific article (publication date: May 2006)

[11C]Choline PET/CT in therapy response assessment of a neoadjuvant therapy in locally advanced and high risk prostate cancer before radical prostatectomy

scientific article published on 27 August 2016

pERK, pAKT and p53 as tissue biomarkers in erlotinib-treated patients with advanced pancreatic cancer: a translational subgroup analysis from AIO-PK0104

scientific article