List of works - Mert Erkan

A common genetic variation of melanoma inhibitory activity-2 labels a subtype of pancreatic adenocarcinoma with high endoplasmic reticulum stress levels

scientific article published on 6 February 2015

A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling

scientific article published on 19 January 2015

Abstract B08: The role of periostin in pancreatic carcinogenesis and metastatic spread

Activated leukocyte cell adhesion molecule regulates the interaction between pancreatic cancer cells and stellate cells

scientific article published on 26 August 2016

Analysis of the extracellular matrix protein periostin in early pancreatic carcinogenesis

scholarly article by Simone Hausmann et al published May 2013 in Pancreatology

Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells

scientific article

Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma

scientific article published on May 2009

Cannabinoids in pancreatic cancer: correlation with survival and pain

scientific article

Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells

scientific article

Co-clinical Assessment of Tumor Cellularity in Pancreatic Cancer

scientific article published on 23 September 2016

Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma

Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

scientific article published on 21 September 2015

Comparative analysis of the revenues of pylorus-preserving pancreatic head resections and laparoscopic cholecystectomies as prototypic surgical procedures in the German health-care system ⬇️

scientific article published on June 19, 2013

Confirmation of DNA microarray-derived differentially expressed genes in pancreatic cancer using quantitative RT-PCR.

scientific article published on 04 August 2009

Contemporary strategies to improve the outcome in locally advanced pancreatic cancer

scientific article

Cystic colon duplication causing intussusception in a 25-year-old man: report of a case and review of the literature

scientific article

Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy

scientific article

Energy metabolism and proliferation in pancreatic carcinogenesis ⬇️

scientific article published on March 20, 2012

Expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in pancreatic neoplasm and pancreatic stellate cells

scientific article published on 25 February 2007

Five years and 4 months of recurrence-free survival in hepatic angiosarcoma ⬇️

scientific article published on January 1, 2003

From tissue turnover to the cell of origin for pancreatic cancer ⬇️

scientific article published on July 12, 2011

Glutamate increases pancreatic cancer cell invasion and migration via AMPA receptor activation and Kras-MAPK signaling

scientific article published on 7 April 2011

Hippo pathway elements Co-localize with Occludin: A possible sensor system in pancreatic epithelial cells

scientific article published on May 2015

How fibrosis influences imaging and surgical decisions in pancreatic cancer ⬇️

scientific article published on October 2, 2012

Hypoxia inducible BHLHB2 is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma

scientific article published on 21 September 2010

Hypoxia-induced endoplasmic reticulum stress characterizes a necrotic phenotype of pancreatic cancer

scientific article published on 5 October 2015

Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes

scientific article

Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms

scientific article

Intracellular autofluorescence: a biomarker for epithelial cancer stem cells

scientific article (publication date: November 2014)

Kif20a inhibition reduces migration and invasion of pancreatic cancer cells

scientific article published on 30 March 2015

Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis

scientific article published in June 2005

Loss of Periostin Results in Impaired Regeneration and Pancreatic Atrophy after Cerulein-Induced Pancreatitis

scientific article published on 27 November 2015

Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice ⬇️

scientific article published on April 8, 2013

Mesenchymal Wt1 positive stellate cells represent a minor source of the fibrotic response in pancreatitis

scholarly article by Ivonne Regel et al published June 2015 in Pancreatology

Mononuclear cells modulate the activity of pancreatic stellate cells which in turn promote fibrosis and inflammation in chronic pancreatitis

scientific article

Multicenter double-blinded randomized controlled trial of standard abdominal wound edge protection with surgical dressings versus coverage with a sterile circular polyethylene drape for prevention of surgical site infections: a CHIR-Net trial (BaFO;

scientific article published on November 2014

Nerve growth factor and artemin are paracrine mediators of pancreatic neuropathy in pancreatic adenocarcinoma

scientific article

Neural fractalkine expression is closely linked to pain and pancreatic neuritis in human chronic pancreatitis

scientific article published on 19 January 2009

Northern blot analysis for detection and quantification of RNA in pancreatic cancer cells and tissues

scientific article

Organ-, inflammation- and cancer specific transcriptional fingerprints of pancreatic and hepatic stellate cells

scientific article

Outcomes of resections for pancreatic adenocarcinoma with suspected venous involvement: a single center experience

scientific article published on 22 August 2015

Overview on how oncogenic Kras promotes pancreatic carcinogenesis by inducing low intracellular ROS levels

scientific article published on 12 September 2013

Palliative Pancreaticoduodenectomy: Benefits and Limitations

Pancreas-specific activation of mTOR and loss of p53 induce tumors reminiscent of acinar cell carcinoma

scientific article

Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver

scientific article published on 6 August 2016

Pancreatic islet and stellate cells are the main sources of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 in pancreatic cancer

scientific article

Periostin and tumor-stroma interactions in non-small cell lung cancer

scientific article published on 14 September 2016

Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity

scientific article published on 25 January 2007

Periostin promotes pancreatic carcinogenesis and metastatic spread

scholarly article by Simone Hausmann et al published June 2015 in Pancreatology

Pigment epithelium-derived factor associates with neuropathy and fibrosis in pancreatic cancer

scientific article published on 11 January 2011

Preoperative acute pancreatitis in periampullary tumors: implications for surgical management

scientific article published on 7 August 2007

Resectability After First-Line FOLFIRINOX in Initially Unresectable Locally Advanced Pancreatic Cancer: A Single-Center Experience

scientific article

Resection of primary pancreatic cancer and liver metastasis: a systematic review

scientific article published on January 2008

Second-look operation for unresectable pancreatic ductal adenocarcinoma at a high-volume center

scientific article

Silencing of GRP94 expression promotes apoptosis in pancreatic cancer cells

scientific article

Standard abdominal wound edge protection with surgical dressings vs coverage with a sterile circular polyethylene drape for prevention of surgical site infections (BaFO): study protocol for a randomized controlled trial

scientific article

StellaTUM: current consensus and discussion on pancreatic stellate cell research

scientific article published on 24 November 2011

Stromal heterogeneity in pancreatic cancer and chronic pancreatitis

scientific article published on 12 May 2018

Surgery for cystic pancreatic lesions in the post-sendai era: a single institution experience

scientific article

Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype

scientific article

Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery

scientific article published on July 2008

Tenascin-C enhances pancreatic cancer cell growth and motility and affects cell adhesion through activation of the integrin pathway

scientific article

The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma

scientific article published on 17 July 2008

The impact of the activated stroma on pancreatic ductal adenocarcinoma biology and therapy resistance

scientific article published on March 2012

The neurotrophic factor artemin influences the extent of neural damage and growth in chronic pancreatitis

scientific article published on 17 October 2006

The neurotrophic factor artemin promotes pancreatic cancer invasion

scientific article published on August 2006

The role of hypoxia in pancreatic cancer: a potential therapeutic target?

scientific article

The role of inflammation in pancreatic cancer

scientific article published on January 2014

The role of pancreatic stellate cells in pancreatic cancer

scientific article published on 05 February 2013

The role of stroma in pancreatic cancer: diagnostic and therapeutic implications ⬇️

scientific article published on June 19, 2012

Tumor metabolism to blood flow ratio in pancreatic cancer: helpful in patient stratification?

scientific article

Tumor-Stromal Interactions in Invasion and Metastases

scholarly article published 2010

Umbilical Microflora, Antiseptic Skin Preparation, and Surgical Site Infection in Abdominal Surgery

scientific article published on 26 June 2015

Understanding the stroma of pancreatic cancer: co-evolution of the microenvironment with epithelial carcinogenesis ⬇️

scientific article published on July 8, 2013

Volumetric gain of the human pancreas after left partial pancreatic resection: A CT-scan based retrospective study

scientific article

List of works by Mert Erkan

A common genetic variation of melanoma inhibitory activity-2 labels a subtype of pancreatic adenocarcinoma with high endoplasmic reticulum stress levels

A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling

Abstract B08: The role of periostin in pancreatic carcinogenesis and metastatic spread

Activated leukocyte cell adhesion molecule regulates the interaction between pancreatic cancer cells and stellate cells

Analysis of the extracellular matrix protein periostin in early pancreatic carcinogenesis

Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells

Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma

Cannabinoids in pancreatic cancer: correlation with survival and pain

Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells

Co-clinical Assessment of Tumor Cellularity in Pancreatic Cancer

Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma

Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

Comparative analysis of the revenues of pylorus-preserving pancreatic head resections and laparoscopic cholecystectomies as prototypic surgical procedures in the German health-care system ⬇️

Confirmation of DNA microarray-derived differentially expressed genes in pancreatic cancer using quantitative RT-PCR.

Contemporary strategies to improve the outcome in locally advanced pancreatic cancer

Cystic colon duplication causing intussusception in a 25-year-old man: report of a case and review of the literature

Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy

Energy metabolism and proliferation in pancreatic carcinogenesis ⬇️

Expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in pancreatic neoplasm and pancreatic stellate cells

Five years and 4 months of recurrence-free survival in hepatic angiosarcoma ⬇️

From tissue turnover to the cell of origin for pancreatic cancer ⬇️

Glutamate increases pancreatic cancer cell invasion and migration via AMPA receptor activation and Kras-MAPK signaling

Hippo pathway elements Co-localize with Occludin: A possible sensor system in pancreatic epithelial cells

How fibrosis influences imaging and surgical decisions in pancreatic cancer ⬇️

Hypoxia inducible BHLHB2 is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma

Hypoxia-induced endoplasmic reticulum stress characterizes a necrotic phenotype of pancreatic cancer

Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes

Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms

Intracellular autofluorescence: a biomarker for epithelial cancer stem cells

Kif20a inhibition reduces migration and invasion of pancreatic cancer cells

Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis

Loss of Periostin Results in Impaired Regeneration and Pancreatic Atrophy after Cerulein-Induced Pancreatitis

Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice ⬇️

Mesenchymal Wt1 positive stellate cells represent a minor source of the fibrotic response in pancreatitis

Mononuclear cells modulate the activity of pancreatic stellate cells which in turn promote fibrosis and inflammation in chronic pancreatitis

Multicenter double-blinded randomized controlled trial of standard abdominal wound edge protection with surgical dressings versus coverage with a sterile circular polyethylene drape for prevention of surgical site infections: a CHIR-Net trial (BaFO;

Nerve growth factor and artemin are paracrine mediators of pancreatic neuropathy in pancreatic adenocarcinoma

Neural fractalkine expression is closely linked to pain and pancreatic neuritis in human chronic pancreatitis

Northern blot analysis for detection and quantification of RNA in pancreatic cancer cells and tissues

Organ-, inflammation- and cancer specific transcriptional fingerprints of pancreatic and hepatic stellate cells

Outcomes of resections for pancreatic adenocarcinoma with suspected venous involvement: a single center experience

Overview on how oncogenic Kras promotes pancreatic carcinogenesis by inducing low intracellular ROS levels

Palliative Pancreaticoduodenectomy: Benefits and Limitations

Pancreas-specific activation of mTOR and loss of p53 induce tumors reminiscent of acinar cell carcinoma

Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver

Pancreatic islet and stellate cells are the main sources of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 in pancreatic cancer

Periostin and tumor-stroma interactions in non-small cell lung cancer

Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity

Periostin promotes pancreatic carcinogenesis and metastatic spread

Pigment epithelium-derived factor associates with neuropathy and fibrosis in pancreatic cancer

Preoperative acute pancreatitis in periampullary tumors: implications for surgical management

Resectability After First-Line FOLFIRINOX in Initially Unresectable Locally Advanced Pancreatic Cancer: A Single-Center Experience

Resection of primary pancreatic cancer and liver metastasis: a systematic review

Second-look operation for unresectable pancreatic ductal adenocarcinoma at a high-volume center

Silencing of GRP94 expression promotes apoptosis in pancreatic cancer cells

Standard abdominal wound edge protection with surgical dressings vs coverage with a sterile circular polyethylene drape for prevention of surgical site infections (BaFO): study protocol for a randomized controlled trial

StellaTUM: current consensus and discussion on pancreatic stellate cell research

Stromal heterogeneity in pancreatic cancer and chronic pancreatitis

Surgery for cystic pancreatic lesions in the post-sendai era: a single institution experience

Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype

Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery

Tenascin-C enhances pancreatic cancer cell growth and motility and affects cell adhesion through activation of the integrin pathway

The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma

The impact of the activated stroma on pancreatic ductal adenocarcinoma biology and therapy resistance

The neurotrophic factor artemin influences the extent of neural damage and growth in chronic pancreatitis

The neurotrophic factor artemin promotes pancreatic cancer invasion

The role of hypoxia in pancreatic cancer: a potential therapeutic target?

The role of inflammation in pancreatic cancer

The role of pancreatic stellate cells in pancreatic cancer

The role of stroma in pancreatic cancer: diagnostic and therapeutic implications ⬇️

Tumor metabolism to blood flow ratio in pancreatic cancer: helpful in patient stratification?

Tumor-Stromal Interactions in Invasion and Metastases

Umbilical Microflora, Antiseptic Skin Preparation, and Surgical Site Infection in Abdominal Surgery

Understanding the stroma of pancreatic cancer: co-evolution of the microenvironment with epithelial carcinogenesis ⬇️

Volumetric gain of the human pancreas after left partial pancreatic resection: A CT-scan based retrospective study