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List of works by Thilo Hackert

A novel animal model of severe pancreatitis in mice and its differences to the rat.

scientific article published on 22 July 2008

A systematic review and meta-analysis of laparoscopic versus open distal pancreatectomy for benign and malignant lesions of the pancreas: it's time to randomize

scientific article

A systematic review and quantitative analysis of different therapies for pancreas divisum

scientific article published on 3 January 2017

Abdominal drainage versus no drainage after distal pancreatectomy: study protocol for a randomized controlled trial

scientific article

Acinar cell carcinoma of the pancreas: is resection justified even in limited metastatic disease?

scientific article published on 27 March 2011

Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study

article published in 2019

Acute retinopathy following pancreatic head resection for chronic pancreatitis: a rare, severe complication.

scientific article published on 10 September 2005

Adjuvant treatment for pancreatic cancer

article published in 2019

Advanced-stage pancreatic cancer: therapy options

scientific article published on 30 April 2013

Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin

scientific article published on 15 October 2020

Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer

scientific article published on 12 December 2018

Alcohol pretreatment increases hepatic and pulmonary injury in experimental pancreatitis.

scientific article published on 29 April 2009

An Innovative Technique for Pancreatic Head Resection: The "Uncinate First" Approach

scientific article published on December 1, 2011

Anaplastic pancreatic cancer: Presentation, surgical management, and outcome

scientific article published on 9 June 2010

Antioxidant Therapy in Acute Pancreatitis: Experimental and Clinical Evidence ⬇️

scientific article published on August 11, 2011

Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer

scientific article published in April 2015

Association of genetic polymorphisms with survival of pancreatic ductal adenocarcinoma patients

scientific article published on 5 August 2016

Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia

scientific article published on 26 November 2015

Bicarbonate buffered peritoneal dialysis fluid upregulates angiopoietin-1 and promotes vessel maturation

scientific article published on 18 December 2017

Borderline resectable pancreatic cancer

scientific article published on 9 March 2016

Buffer-dependent regulation of aquaporin-1 expression and function in human peritoneal mesothelial cells ⬇️

scientific article published on March 1, 2012

CA19-9 in potentially resectable pancreatic cancer: perspective to adjust surgical and perioperative therapy

scientific article

CD44/CD44v6 a Reliable Companion in Cancer-Initiating Cell Maintenance and Tumor Progression

CD44v6-competent tumor exosomes promote motility, invasion and cancer-initiating cell marker expression in pancreatic and colorectal cancer cells

scientific article published on 13 July 2016

CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma

scientific article published on 8 February 2016

Capsaicin reduces tissue damage in experimental acute pancreatitis.

scientific article published in August 2009

Cardiorespiratory fitness and muscle strength in pancreatic cancer patients

scientific article published on 17 April 2017

Changes in the microarchitecture of the pancreatic cancer stroma are linked to neutrophil-dependent reprogramming of stellate cells and reflected by diffusion-weighted magnetic resonance imaging

scientific article published in January 2018

Clinical Impact of Structured Follow-up After Pancreatic Surgery

scientific article

Clinical phase I/II trial to investigate neoadjuvant intensity-modulated short term radiation therapy (5 × 5 Gy) and intraoperative radiation therapy (15 Gy) in patients with primarily resectable pancreatic cancer - NEOPANC

scientific article published on 23 March 2012

Clinicopathologic characteristics of patients with resected multifocal intraductal papillary mucinous neoplasm of the pancreas

scientific article

Combined microRNA and mRNA microfluidic TaqMan array cards for the diagnosis of malignancy of multiple types of pancreatico-biliary tumors in fine-needle aspiration material

scientific article published on 21 November 2017

Common germline variants within the CDKN2A/2B region affect risk of pancreatic neuroendocrine tumors

scientific article

Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial ⬇️

scientific article published on 24 January 2017

Comparison of the tumor cell secretome and patient sera for an accurate serum-based diagnosis of pancreatic ductal adenocarcinoma

scientific article published on 02 January 2017

Continued Weight Loss and Sarcopenia Predict Poor Outcomes in Locally Advanced Pancreatic Cancer Treated with Chemoradiation

scientific article published on 23 May 2019

Correlation of Histological Vessel Characteristics and Diffusion-Weighted Imaging Intravoxel Incoherent Motion-Derived Parameters in Pancreatic Ductal Adenocarcinomas and Pancreatic Neuroendocrine Tumors

scientific article published on 16 July 2015

Corrigendum to "Distorted leukocyte migration, angiogenesis, wound repair and metastasis in Tspan8 and Tspan8/CD151 double knockout mice indicate complementary activities of Tspan8 and CD51" [Biochim. Biophys. Acta 1865(2) (2018) 379-391].

scientific article published on 20 January 2018

Current State of Surgical Management of Pancreatic Cancer ⬇️

scientific article published on March 10, 2011

Current State of Vascular Resections in Pancreatic Cancer Surgery

scientific article

Decision Making in Necrotizing Pancreatitis

scientific article published on 22 June 2016

Decrease in clinically relevant pancreatic fistula by coverage of the pancreatic remnant after distal pancreatectomy

scientific article published on 18 July 2012

Detection of Hot-Spot Mutations in Circulating Cell-Free DNA From Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas

scientific article published on 22 June 2016

Dexamethasone mediates pancreatic cancer progression by glucocorticoid receptor, TGFβ and JNK/AP-1.

scientific article published on 5 October 2017

Distal Pancreatectomy with Celiac Axis Resection (DP-CAR) for Pancreatic Cancer. How I do It

article by Sjors Klompmaker et al published October 2018 in Journal of Gastrointestinal Surgery

Distinct pathophysiological cytokine profiles for discrimination between autoimmune pancreatitis, chronic pancreatitis, and pancreatic ductal adenocarcinoma

scientific article published on 2 June 2017

Distorted leukocyte migration, angiogenesis, wound repair and metastasis in Tspan8 and Tspan8/CD151 double knockout mice indicate complementary activities of Tspan8 and CD51.

scientific article published on 11 November 2017

Do pancreatic cancer and chronic pancreatitis share the same genetic risk factors? A PANcreatic Disease ReseArch (PANDoRA) consortium investigation

scientific article published on 15 September 2017

Dual-energy CT iodine maps as an alternative quantitative imaging biomarker to abdominal CT perfusion: determination of appropriate trigger delays for acquisition using bolus tracking.

scientific article published on 15 February 2018

Duodenum-preserving pancreatic head resection: 10-year follow-up of a randomized controlled trial comparing the Beger procedure with the Berne modification

scientific article

Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy

scientific article

Early Epigenetic Downregulation of microRNA-192 Expression Promotes Pancreatic Cancer Progression

scientific article published on 23 May 2016

Effectiveness of Tachosil(®) in the prevention of postoperative pancreatic fistula after distal pancreatectomy: a systematic review and meta-analysis

scientific article published on 20 February 2016

Effectiveness of triclosan-coated PDS Plus versus uncoated PDS II sutures for prevention of surgical site infection after abdominal wall closure: the randomised controlled PROUD trial

scientific article published on 7 April 2014

Effects of gadolinium chloride and glycine on hepatic and pancreatic tissue damage in alcoholic pancreatitis

scientific article published in May 2010

Effects of heparin in experimental models of acute pancreatitis and post-ERCP pancreatitis

scientific article

Effects of pantoprazole in experimental acute pancreatitis

scientific article published on 17 September 2010

Efficacy of vaccination with tumor-exosome loaded dendritic cells combined with cytotoxic drug treatment in pancreatic cancer

scientific article published on 20 April 2017

Emergency pancreatic surgery--demanding and dangerous

scientific article

Endogenous CHRNA7-ligand SLURP1 as a potential tumor suppressor and anti-nicotinic factor in pancreatic cancer

scientific article published on 24 January 2018

Enterokinase induces severe necrosis and rapid mortality in cerulein pancreatitis: characterization of a novel noninvasive rat model of necro-hemorrhagic pancreatitis

scientific article published on September 2007

Enucleation: A treatment alternative for branch duct intraductal papillary mucinous neoplasms

scientific article published on 21 November 2016

Epithelial to Stromal Re-Distribution of Primary Cilia during Pancreatic Carcinogenesis

scientific article

Establishment and Characterization of a Novel Cell Line, ASAN-PaCa, Derived From Human Adenocarcinoma Arising in Intraductal Papillary Mucinous Neoplasm of the Pancreas

scientific article published on 11 August 2016

Expanding the indications of pancreas transplantation alone

scientific article

Experimental in vivo and in vitro treatment with a new histone deacetylase inhibitor belinostat inhibits the growth of pancreatic cancer ⬇️

scientific article published on June 8, 2012

Expression and function of matrix Gla protein in human peritoneal mesothelial cells

scientific article published on 5 April 2010

Expression of DRD2 Is Increased in Human Pancreatic Ductal Adenocarcinoma and Inhibitors Slow Tumor Growth in Mice

scientific article published on 28 August 2016

Extended Pancreatectomy: Does It Have a Role in the Contemporary Management of Pancreatic Adenocarcinoma?

scientific article

Extrapancreatic malignancies in patients with pancreatic cancer: epidemiology and clinical consequences

scientific article published in March 2012

Fluid collection after distal pancreatectomy: a frequent finding

scientific article published on 18 November 2015

Functional single nucleotide polymorphisms within the cyclin-dependent kinase inhibitor 2A/2B region affect pancreatic cancer risk

scientific article published on 29 July 2016

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers

scientific article published on February 2015

Genome-wide association study data reveal genetic susceptibility to chronic inflammatory intestinal diseases and pancreatic ductal adenocarcinoma risk

scientific article published on 08 July 2020

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

scientific article published on 8 February 2018

Gut microbiome patterns correlate with higher postoperative complication rates after pancreatic surgery

scientific article published in 2019

HYAL2 methylation in peripheral blood as a potential marker for the detection of pancreatic cancer: a case control study

scientific article published on 27 June 2017

Hypercoagulability after distal pancreatectomy: Just meaningless alterations?

scientific article

Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma

scientific article

Indikation zur Resektion beim Pankreaskarzinom – Wann ist eine Resektion vorteilhaft für den Patienten?

Inflammatory profiling of early experimental necrotizing pancreatitis

scientific article

Inosine reduces microcirculatory disturbance and inflammatory organ damage in experimental acute pancreatitis in rats

scientific article published in April 2006

Interference of peritoneal dialysis fluids with cell cycle mechanisms

scientific article published on 31 July 2014

Interferon-alpha in combination with chemotherapy has potent antiangiogenic properties in an orthotopic mouse model for pancreatic adenocarcinoma

scientific article published on January 2008

International consensus on definition and criteria of borderline resectable pancreatic ductal adenocarcinoma 2017.

scientific article

Intraductal papillary mucinous neoplasms of the pancreas: radiological predictors of malignant transformation and the introduction of bile duct dilation to current guidelines

scientific article published on 09 March 2016

Intrapulmonal dislocation of a totally implantable venous access device

scientific article

Invited commentary on “A systematic review of POSSUM and P-POSSUM as predictors of postoperative morbidity and mortality in patients undergoing pancreatic surgery” ⬇️

scientific article published on 04 February 2013

Ischemic acute pancreatitis: clinical features of 11 patients and review of the literature

scientific article published on 07 September 2008

Lack of Association for Reported Endocrine Pancreatic Cancer Risk Loci in the PANDoRA Consortium

scientific article published on August 2017

Locally Advanced Pancreatic Cancer: Neoadjuvant Therapy With Folfirinox Results in Resectability in 60% of the Patients

scientific article published on 28 June 2016

Location of a biliary leak after liver resection determines success of endoscopic treatment

scientific article

Main- and Branch-Duct Intraductal Papillary Mucinous Neoplasms: Extent of Surgical Resection

scientific article (publication date: February 2015)

Main-duct Intraductal Papillary Mucinous Neoplasm: High Cancer Risk in Duct Diameter of 5 to 9 mm

scientific article published on November 2015

Management of the pancreatic transection plane after left (distal) pancreatectomy: Expert consensus guidelines by the International Study Group of Pancreatic Surgery (ISGPS)

scientific article published on 02 April 2020

Mendelian randomization analysis of n-6 polyunsaturated fatty acid levels and pancreatic cancer risk

scientific article published on 23 September 2020

Mesocaval stenting for therapy of portal hypertension after orthotopic liver transplantation

scientific article published in November 2006

Meta-analysis of delayed gastric emptying after pylorus-preserving versus pylorus-resecting pancreatoduodenectomy.

scientific article published on 7 February 2018

Meta-analysis of effect of routine enteral nutrition on postoperative outcomes after pancreatoduodenectomy

scientific article published on 26 June 2019

Meta-analysis of recurrence pattern after resection for pancreatic cancer

scientific article published on 27 August 2019

Modern phase-specific management of acute pancreatitis

scientific article

Multiple von Meyenburg complexes mimicking diffuse liver metastases from esophageal squamous cell carcinoma

scientific article published on July 2006

Multivisceral resection for pancreatic malignancies: risk-analysis and long-term outcome

scientific article published in July 2009

No Need for Routine Drainage After Pancreatic Head Resection: The Dual-Center, Randomized, Controlled PANDRA Trial (ISRCTN04937707).

scientific article published on September 2016

Nutritional Risk in Major Abdominal Surgery: Protocol of a Prospective Observational Trial to Evaluate the Prognostic Value of Different Nutritional Scores in Pancreatic Surgery.

scientific article

Nutritional support and therapy in pancreatic surgery: A position paper of the International Study Group on Pancreatic Surgery (ISGPS)

scientific article published on 17 July 2018

Overcoming chemoresistance in pancreatic cancer cells: role of the bitter taste receptor T2R10.

scientific article

P-selectin inhibition reduces severity of acute experimental pancreatitis

scientific journal article

Palliative resection of the primary tumor in 442 metastasized neuroendocrine tumors of the pancreas: a population-based, propensity score-matched survival analysis

scientific article published on 22 July 2015

Pancreatic Cancer Surgery: The New R-status Counts

scientific article

Pancreatic Cancer: Advances in Treatment, Results and Limitations ⬇️

scientific article published on June 17, 2013

Pancreatic anastomosis after pancreatoduodenectomy: A position statement by the International Study Group of Pancreatic Surgery (ISGPS).

scientific article published on 24 December 2016

Pancreatic cancer surgery in the new millennium: better prediction of outcome

scientific article

Pancreatic intraductal papillary mucinous neoplasm--where is the challenge?

scientific article published on 17 December 2014

Pancreatic main-duct involvement in branch-duct IPMNs: an underestimated risk

scientific article published in November 2014

Pancreatic surgery: we need clear definitions

scientific article published on 06 November 2018

Pancreatoduodenectomy with colon resection for pancreatic cancer: a systematic review

scientific article published on 25 April 2018

Partial pancreatoduodenectomy versus duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial

scientific article

Pilot study evaluating broccoli sprouts in advanced pancreatic cancer (POUDER trial) - study protocol for a randomized controlled trial

scientific article

Platelet function in acute experimental pancreatitis

scientific article published on April 2007

Postoperative outcome and quality of life after surgery for FAP-associated duodenal adenomatosis

scientific article published on 26 October 2017

Postoperative pancreatic fistula

scientific article published on 13 December 2010

Postoperative pancreatic fistula: We need to redefine grades B and C.

scientific article published on 22 October 2015

Precancerous Lesions and Carcinoma of the Pancreas

scientific article published on 3 February 2015

Precancerous Lesions and Carcinoma of the Pancreas

scientific article published on February 2015

Predictive performance of factors associated with malignancy in intraductal papillary mucinous neoplasia of the pancreas

scientific article published on 05 February 2018

Preoperative Serum Thymidine Kinase Activity as Novel Monitoring, Prognostic, and Predictive Biomarker in Pancreatic Cancer

scientific article published on 16 November 2017

Prophylactic antibiotic treatment is superior to therapy on-demand in experimental necrotising pancreatitis

scientific article

Protective effects and anti-inflammatory pathways of exogenous calcitonin gene-related peptide in severe necrotizing pancreatitis

scientific article published on 14 August 2009

Pylorus Resection Does Not Reduce Delayed Gastric Emptying After Partial Pancreatoduodenectomy: A Blinded Randomized Controlled Trial (PROPP Study, DRKS00004191).

scientific article published on 6 September 2017

Pylorus preservation pancreatectomy or not

Pylorus resection or pylorus preservation in partial pancreatico-duodenectomy (PROPP study): study protocol for a randomized controlled trial

scientific article published on 14 February 2013

RIP3 attenuates the pancreatic damage induced by deletion of ATG7.

scientific article

Radical pancreatic cancer surgery-with arterial resection

Radiologic versus endoscopic evaluation of the conduit after esophageal resection: a prospective, blinded, intraindividually controlled diagnostic study

scientific article published on 12 February 2014

Reactive Hypertrophy of an Accessory Spleen Mimicking Tumour Recurrence of Metastatic Renal Cell Carcinoma ⬇️

scientific article published on January 1, 2011

Reduction of ischemia/reperfusion injury by antithrombin III after experimental pancreas transplantation

scientific article published in January 2005

Reinsertion of the gastric coronary vein to avoid venous gastric congestion in pancreatic surgery

scientific article published on 24 July 2014

Remnant closure after distal pancreatectomy: Current state and future perspectives ⬇️

scientific article published on November 23, 2011

Renal tumors and second primary pancreatic tumors: a relationship with clinical impact? ⬇️

scientific article published on August 8, 2012

Reply to Letter: "Concerns About Acute Cholecystitis: Early Versus Delayed Cholecystectomy--A Multicenter Randomized Trial".

scientific article published in August 2015

Resection of pancreatic cancer in Europe and USA: an international large-scale study highlighting large variations

scientific article published on 20 November 2017

Response to the Letter to the Editor "Pancreatic Cancer and FOLFIRINOX: Should We Resect All Responders?" by Neoptolemos and Colleagues

scientific article published in February 2018

Retrospective electron microscopy: Preservation of fine structure by freezing and aldehyde fixation

scientific article published on 27 October 2016

SLC22A3 polymorphisms do not modify pancreatic cancer risk, but may influence overall patient survival

scientific article published on 08 March 2017

Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.

scientific article

Severe acute pancreatitis: surgical indications and treatment

scientific article published on 10 September 2020

Small (Sendai negative) branch-duct IPMNs: not harmless

scientific article published in August 2012

Sphincter of Oddi botulinum toxin injection to prevent pancreatic fistula after distal pancreatectomy

scientific article

Sphincter-Preserving Surgery for Low Rectal Cancer: Do We Overshoot the Mark?

scientific article

Standards for reporting on surgery for chronic pancreatitis: a report from the International Study Group for Pancreatic Surgery (ISGPS)

scientific article published on 14 March 2020

Stimulation of Central α2 Receptors Attenuates Experimental Necrotizing Pancreatitis

scientific article published in February 2016

Stratification of pancreatic tissue samples for molecular studies: RNA-based cellular annotation procedure

scientific article

Successful ablation of lymph nodes using irreversible electroporation (IRE) in a porcine survival model

scientific article published on 4 April 2017

Successful doxycycline treatment of lymphatic fistulas: report of five cases and review of the literature

scientific article

Superselective embolization for the management of postpancreatectomy hemorrhage: a single-center experience in 25 patients

scientific article published on 22 February 2012

Surgery for Pancreatic Cancer after neoadjuvant treatment

scientific article published on 10 September 2018

Surgical ampullectomy: an underestimated operation in the era of endoscopy

scientific article published on 8 December 2015

Survival data justifies resection for pancreatic metastases

scientific article

Symptoms and Surgical Management of a Distal Choledochal Cyst in a Patient with Pancreas Divisum: Case Report and Review of the Literature ⬇️

scientific article published on 02 October 2007

Systematic review of the quantity and quality of randomized clinical trials in pancreatic surgery

scientific article published on 01 January 2019

TERT gene harbors multiple variants associated with pancreatic cancer susceptibility

scientific article

Targeting P-selectin in acute pancreatitis

scientific article published on September 2010

Teres Hepatis Ligament Flap Plasty to Prevent Pancreatic Fistula after Tumor Enucleation ⬇️

scientific article published on October 1, 2013

Teres Ligament Patch Reduces Relevant Morbidity After Distal Pancreatectomy (the DISCOVER Randomized Controlled Trial).

scientific article published on 22 July 2016

The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After

scientific article published on 28 December 2016

The Pancreas: Causes for Malabsorption

scientific article

The Sendai and Fukuoka consensus criteria for the management of branch duct IPMN - A meta-analysis on their accuracy

scientific article published on February 2017

The TRIANGLE operation - radical surgery after neoadjuvant treatment for advanced pancreatic cancer: a single arm observational study

scientific article published on 21 August 2017

The bile acid receptor FXR attenuates acinar cell autophagy in chronic pancreatitis

scientific article

The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulators

scientific article published on 3 August 2017

Total pancreatectomy for primary pancreatic neoplasms: renaissance of an unpopular operation

scientific article

Toward the blood-borne miRNome of human diseases

scientific article

Transcriptional variations in the wider peritumoral tissue environment of pancreatic cancer

scientific article published on 6 October 2017

Tspan8 and Tspan8/CD151 knockout mice unravel the contribution of tumor and host exosomes to tumor progression

Underutilization of Surgery in Periampullary Cancer Treatment

scientific article published on 07 August 2018

Validation of at least 1 mm as cut-off for resection margins for pancreatic adenocarcinoma of the body and tail

scientific article published on 08 May 2018

Vascular Resection in Pancreatic Cancer

scientific article

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