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List of works by Julia Mayerle

3rd St. Gallen EORTC Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of pancreatic cancer

scientific article

50 years of progress in pathophysiology, diagnosis and treatment of chronic pancreatitis ⬇️

scientific article published on April 12, 2013

A Syngeneic Orthotopic Murine Model of Pancreatic Adenocarcinoma in the C57/BL6 Mouse Using the Panc02 and 6606PDA Cell Lines ⬇️

scientific article published on June 30, 2011

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

scientific article published on 19 October 2015

A novel role for leucocytes in determining the severity of acute pancreatitis

scientific article published in November 2009

A randomized multicentre phase II trial comparing adjuvant therapy in patients with interferon alpha-2b and 5-FU alone or in combination with either external radiation treatment and cisplatin (CapRI) or radiation alone regarding event-free survival -

A randomized, phase III trial of capecitabine plus bevacizumab (Cape-Bev) versus capecitabine plus irinotecan plus bevacizumab (CAPIRI-Bev) in first-line treatment of metastatic colorectal cancer: the AIO KRK 0110 trial/ML22011 trial

scientific article

A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis

scientific article published on 16 March 2015

A structured weight loss program increases gut microbiota phylogenetic diversity and reduces levels of Collinsella in obese type 2 diabetics: A pilot study

scientific article published on 18 July 2019

ABO blood type B and fucosyltransferase 2 non-secretor status as genetic risk factors for chronic pancreatitis

article published in 2015

Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis-Knowledge Gaps and Research Opportunities: Overview Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop

scientific article published on 01 November 2018

Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis: Summary of the Working Group on Drug Development and Trials in Chronic Pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases Workshop

article

Acute Pancreatitis-Progress and Challenges: A Report on an International Symposium

scientific article

Advanced neuroendocrine tumours of the small intestine and pancreas: clinical developments, controversies, and future strategies

scientific article published on 8 December 2017

Advances in the etiology of chronic pancreatitis.

scientific article published on September 2010

Age independent survival benefit for patients with hepatocellular carcinoma (HCC) without metastases at diagnosis: a population-based study

scientific article published on 16 March 2019

Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis.

scientific article

Anatomic variants of the pancreatic duct and their clinical relevance: an MR-guided study in the general population

scientific article published on 15 August 2014

Angiopoietin-2, a regulator of vascular permeability in inflammation, is associated with persistent organ failure in patients with acute pancreatitis from the United States and Germany

scientific article published on 11 May 2010

Animal models for investigating chronic pancreatitis.

scientific article published on December 2011

Antibiotic therapy in acute pancreatitis: From global overuse to evidence based recommendations

scientific article published on 19 April 2019

Antifibrotic effects of hypocalcemic vitamin D analogs in murine and human hepatic stellate cells and in the CCl4 mouse model

scientific article published on 29 August 2019

Association analysis of genetic variants in the myosin IXB gene in acute pancreatitis

scientific article

Autoimmune pancreatitis in MRL/Mp mice is a T cell-mediated disease responsive to cyclosporine A and rapamycin treatment

article

Breaking down haem attenuates acute pancreatitis: a new treatment option?

scientific article published on 11 February 2011

Cathepsin B Activity Initiates Apoptosis via Digestive Protease Activation in Pancreatic Acinar Cells and Experimental Pancreatitis.

scientific article published on 12 May 2016

Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice

scientific article published on 09 December 2011

Cathepsin B-mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice.

scientific article published on 24 October 2017

Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis.

scientific article published on 11 December 2017

Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.

scientific article published on 10 November 2009

Cell biology of pancreatic proteases

scientific article

Changes in pathogen spectrum and antimicrobial resistance development in the time-course of acute necrotizing pancreatitis

scientific article published on 23 July 2019

Chronic pancreatitis

scientific article published on 7 September 2017

Chronic pancreatitis as a risk factor for the development of pancreatic cancer--diagnostic challenges

scientific article published in April 2010

Chronic pancreatitis--definition, etiology, investigation and treatment

scientific article published on 31 May 2013

Chronic stress increases experimental pancreatic cancer growth, reduces survival and can be antagonised by beta-adrenergic receptor blockade.

scientific article published on 23 March 2016

Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for pancreatic and colorectal adenocarcinoma

scientific article published on 14 September 2012

Clinical Profile of Autoimmune Pancreatitis and Its Histological Subtypes

scientific article published on 01 August 2011

Clinical utility gene card for: Johanson-Blizzard syndrome

scientific article published on 8 May 2013

Cohort Profile: The Study of Health in Pomerania

article

Cohort profile: Greifswald approach to individualized medicine (GANI_MED)

scientific article

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

scientific article

Common variants in the CLDN2 - MORC4 and PRSS1 - PRSS2 loci confer susceptibility to acute pancreatitis

scientific article published on 01 June 2018

Complement Component 5 Mediates Development of Fibrosis, via Activation of Stellate Cells, in 2 Mouse Models of Chronic Pancreatitis

scientific article

Conservative treatment of acute pancreatitis

scientific article

Correlation Between Baseline Osteoprotegerin Serum Levels and Prognosis of Advanced-Stage Colorectal Cancer Patients

scientific article published on 29 January 2018

Cyst Features and Risk of Malignancy in Intraductal Papillary Mucinous Neoplasms of the Pancreas: Imaging and Pathology

scientific article (publication date: February 2015)

Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)

scientific article

Deficiency of cathepsin C ameliorates severity of acute pancreatitis by reduction of neutrophil elastase activation and cleavage of E-cadherin

scientific article published on 19 November 2018

Defining chronic pancreatitis with a focus on pathological stress responses.

scientific article

Delayed severe bleeding complications after treatment of pancreatic fluid collections with lumen-apposing metal stents

scientific article published on 12 January 2017

Describing Peripancreatic Collections According to the Revised Atlanta Classification of Acute Pancreatitis: An International Interobserver Agreement Study

scientific article published in August 2017

Development and Validation of a Chronic Pancreatitis Prognosis Score in 2 Independent cohorts

scientific article published on 14 September 2017

Development of Pancreatic Cancer: Targets for Early Detection and Treatment.

scientific article published on 22 June 2016

Development, external validation, and comparative assessment of a new diagnostic score for hepatic steatosis

scientific article published on 24 June 2014

Developmental and metabolic disorders of the pancreas

scientific article

Diagnostic and Treatment Algorithms of Pancreatic Cystic Tumors

scientific article published on 22 June 2018

Differential roles of inflammatory cells in pancreatitis.

scientific article published on March 2012

Do Genetic Markers of Inflammation Modify the Relationship between Periodontitis and Nonalcoholic Fatty Liver Disease? Findings from the SHIP Study

scientific article published on July 2017

Drug efflux transporter multidrug resistance-associated protein 5 affects sensitivity of pancreatic cancer cell lines to the nucleoside anticancer drug 5-fluorouracil

scientific article published on 7 October 2010

Drug induced pancreatitis.

scientific article published on April 2010

Drug-induced pancreatitis.

scientific article published on April 2012

Ductal Mucus Obstruction and Reduced Fluid Secretion Are Early Defects in Chronic Pancreatitis.

scientific article

Early Parenteral Nutrition in Patients with Biliopancreatic Mass Lesions, a Prospective, Randomized Intervention Trial

scientific article

Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice

scientific article published on 30 July 2019

Early zymogen activation in response to autophagy modulation in caerulein hyperstimulated mice

Economic aspects of inpatient treatment for decompensated liver cirrhosis: a prospective study employing an evidence-based clinical pathway

scientific article published on 8 January 2013

Effect of ethanol on inflammatory responses. Implications for pancreatitis

scientific article published on 21 June 2007

Effect of magnesium supplementation and depletion on the onset and course of acute experimental pancreatitis

scientific article published on 25 November 2013

Effect of oral administration of AZD8309, a CXCR2 antagonist, on the severity of experimental pancreatitis

scientific article published on 14 July 2016

Effect of pancreas-specific Atg5-deficiency on zymogen activation in murine chronic pancreatitis

Environmental risk factors for chronic pancreatitis and pancreatic cancer.

scientific article published on 05 July 2011

Erratum: Corrigendum: Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)

scholarly article published in Nature Genetics

Evaluating the best empirical antibiotic therapy in patients with acute-on-chronic liver failure and spontaneous bacterial peritonitis

scientific article published on 31 March 2019

Evaluation of genome-wide loci of iron metabolism in hereditary hemochromatosis identifies PCSK7 as a host risk factor of liver cirrhosis

scientific article published on 20 February 2014

Evidence-Based Surgical Treatments for Chronic Pancreatitis

scientific article published on July 2016

Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

scientific article published on 24 January 2018

Extending laboratory automation to the wards: effect of an innovative pneumatic tube system on diagnostic samples and transport time

scientific article published on 30 June 2016

Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts

scientific article published on 15 October 2015

Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis

scientific article

Extracellular cleavage of E-cadherin by leukocyte elastase during acute experimental pancreatitis in rats

scientific article published in October 2005

Fucosyltransferase 2 (FUT2) non-secretor status and blood group B are associated with elevated serum lipase activity in asymptomatic subjects, and an increased risk for chronic pancreatitis: a genetic association study

Functional abdominal pain and discomfort (IBS) is not associated with faecal microbiota composition in the general population

article

Future research demands of the United European Gastroenterology (UEG) and its member societies

scientific article published on 21 June 2019

Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus

scientific article published on 25 January 2013

Genetic basis and pancreatic biology of Johanson-Blizzard syndrome

scientific article

Genetic susceptibility factors for alcohol-induced chronic pancreatitis.

scientific article published on 18 June 2015

Genetic variants associated with susceptibility to Helicobacter pylori--reply

scientific article published in September 2013

Genetics, Cell Biology, and Pathophysiology of Pancreatitis

scientific article published on 18 January 2019

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis

scientific article

Geriatric nutritional risk index correlates with length of hospital stay and inflammatory markers in older inpatients.

scientific article published on 9 July 2016

Germline mutations and gene polymorphism associated with human pancreatitis

scientific article

Helicobacter pylori colonization and obesity - a Mendelian randomization study

scientific article published on 31 October 2017

Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen

scientific article published on 21 November 2001

Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling

scientific article

Hyperthyroid and acute tonsillitis in a 23-year-old woman

scientific article

Identification of genetic loci associated with Helicobacter pylori serologic status

scientific article published in May 2013

IgG4-related autoimmune diseases: Polymorphous presentation complicates diagnosis and treatment

scientific article

IgG4-related disease: a new kid on the block or an old aquaintance?

scientific article

Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma

scientific article published on 06 August 2018

Impaired Exocrine Pancreatic Function Associates With Changes in Intestinal Microbiota Composition and Diversity

article

In vivo imaging of pancreatic tumours and liver metastases using 7 Tesla MRI in a murine orthotopic pancreatic cancer model and a liver metastases model

scientific article

Interventional Endoscopy--Opportunities and Limitations

scientific article published on February 2016

Intraductal papillary mucinous neoplasia: which findings support observation?

scientific article published in February 2012

Is hepatic steatosis associated with left ventricular mass index increase in the general population?

scientific article

Is it necessary to distinguish between alcoholic and nonalcoholic chronic pancreatitis?

scientific article published on January 2007

Johanson-Blizzard syndrome: report of a novel mutation and severe liver involvement.

scientific article

L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN)--a randomized multicentre trial

scientific article

Local clustering of PRSS1 R122H mutations in hereditary pancreatitis patients from Northern Germany

scientific article published on 8 August 2008

Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function

scientific article published on 09 November 2020

Loss of TLR3 and its downstream signaling accelerates acinar cell damage in the acute phase of pancreatitis

scientific article published on 15 December 2018

Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis

scientific article

Magnetic Resonance Imaging of Changes in Abdominal Compartments in Obese Diabetics during a Low-Calorie Weight-Loss Program

scientific article

Management Algorithm for Cystic Pancreatic Lesions

scientific article published on 13 June 2018

Medical treatment of acute pancreatitis

scientific article

Metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis.

scientific article published on 20 January 2017

Metabolic biomarkers for the differential diagnosis of pancreatic ductal adenocarcinoma vs. chronic pancreatitis

scientific article published on 28 May 2014

Mnk1 is a novel acinar cell-specific kinase required for exocrine pancreatic secretion and response to pancreatitis in mice.

scientific article published on 18 July 2014

Molecular, Biochemical, and Metabolic Abnormalities of Acute Pancreatitis

Multifunctional gold nanorods for selective plasmonic photothermal therapy in pancreatic cancer cells using ultra-short pulse near-infrared laser irradiation.

scientific article published on March 2015

Mutations in the human UBR1 gene and the associated phenotypic spectrum

scientific article published on 09 April 2014

Necrosis, Apoptosis, Necroptosis, Pyroptosis: It Matters How Acinar Cells Die During Pancreatitis.

scientific article published on 31 May 2016

Newcastle disease virus mediates pancreatic tumor rejection via NK cell activation and prevents cancer relapse by prompting adaptive immunity.

scientific article published on 31 August 2017

Noninvasive quantification of hepatic fat content using three-echo dixon magnetic resonance imaging with correction for T2* relaxation effects

scientific article published in December 2011

Optimal duration and timing of adjuvant chemotherapy after definitive surgery for ductal adenocarcinoma of the pancreas: ongoing lessons from the ESPAC-3 study

scientific article

Optimal timing of oral refeeding in mild acute pancreatitis: results of an open randomized multicenter trial.

scientific article

Pancreatic Steatosis Demonstrated at MR Imaging in the General Population: Clinical Relevance

scientific article

Pancreatic cancer hENT1 expression and survival from gemcitabine in patients from the ESPAC-3 trial

scientific article

Pancreatic cancer in 2015: Precision medicine in pancreatic cancer--fact or fiction?

scientific article

Pancreatic diseases: update 2011

scientific article

Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches

scientific article published on 08 August 2019

Pancreatic pseudocysts--when and how to treat?

scientific article

Pancreatic pseudocysts: observation, endoscopic drainage, or resection?

scientific article published on 18 September 2009

Pathophysiology of alcohol-induced pancreatitis

scientific article published in November 2003

Patterns of Recurrence After Resection of Pancreatic Ductal Adenocarcinoma: A Secondary Analysis of the ESPAC-4 Randomized Adjuvant Chemotherapy Trial

scientific article published on 04 September 2019

Periodontitis and Non-alcoholic Fatty Liver Disease, a population based cohort investigation in the Study of Health in Pomerania.

scientific article published on 14 August 2017

Perivascular Tumor-Infiltrating Leukocyte Scoring for Prognosis of Resected Hepatocellular Carcinoma Patients

scientific article published on 18 October 2018

Plasma protein profiling of patients with intraductal papillary mucinous neoplasm of the pancreas as potential precursor lesions of pancreatic cancer

scientific article published on 5 December 2017

Pre-study protocol MagPEP: a multicentre randomized controlled trial of magnesium sulphate in the prevention of post-ERCP pancreatitis

scientific article

Precancerous Lesions and Carcinoma of the Pancreas

scientific article published on February 2015

Precancerous Lesions and Carcinoma of the Pancreas

scientific article published on 3 February 2015

Predictive factors for and incidence of hospital readmissions of patients with acute and chronic pancreatitis.

scientific article published on 31 March 2015

Predictors of ribociclib-mediated antitumour effects in native and sorafenib-resistant human hepatocellular carcinoma cells

scientific article published on 27 June 2019

Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis

scientific article

Prevalence and determinants of increased serum lipase levels in a general population

scientific article published in November 2008

Prevalence of Fatty Liver Disease and Hepatic Iron Overload in a Northeastern German Population by Using Quantitative MR Imaging.

scientific article published on 5 May 2017

Preventing pancreatitis by protecting the mitochondrial permeability transition pore

scientific article published on 20 December 2012

Prophylactic glycine administration attenuates pancreatic damage and inflammation in experimental acute pancreatitis

scientific article published on 08 April 2011

Prospective cohort study comparing transient EUS guided elastography to EUS-FNA for the diagnosis of solid pancreatic mass lesions

scientific article published on 02 November 2015

Prospective study on the incidence, prevalence and 5-year pancreatic-related mortality of pancreatic cysts in a population-based study.

scientific article published on 6 September 2017

Quantitative chemical shift-encoded MRI is an accurate method to quantify hepatic steatosis

scientific article

Recommendations from the United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis

Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer

scientific article published on 05 December 2011

Reducing uncertainty in estimating associations of oral exposures with Helicobacter pylori serology in the general population

scientific article published on 27 July 2018

Reply

scientific article published on 03 April 2018

Ring1b-dependent epigenetic remodelling is an essential prerequisite for pancreatic carcinogenesis

scientific article published on 06 April 2019

Risk Stratification and Early Conservative Treatment of Acute Pancreatitis

scientific article published on 25 March 2019

Role of endoplasmic reticulum stress and protein misfolding in disorders of the liver and pancreas

scientific article published on 09 April 2019

Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges

scientific article published on 13 July 2017

S2k-guideline Helicobacter pylori and gastroduodenal ulcer disease

scientific article published on April 2016

S3-guideline exocrine pancreatic cancer

scientific article

Secretin-stimulated MRCP in volunteers: assessment of safety, duct visualization, and pancreatic exocrine function

scientific article published on 01 January 2014

Subdiaphragmatic vagotomy promotes tumor growth and reduces survival via TNFα in a murine pancreatic cancer model.

scientific article

Subjects with sonographical hepatic steatosis should be excluded from studies to establish upper reference levels of serum transaminases

scientific article published on 15 November 2010

Suppression of transforming growth factor beta signalling aborts caerulein induced pancreatitis and eliminates restricted stimulation at high caerulein concentrations

scientific article published on 29 November 2006

T1 bias in chemical shift-encoded liver fat-fraction: role of the flip angle

scientific article published on 15 November 2013

The Clinical and Socio-Economic Relevance of Increased IPMN Detection Rates and Management Choices

scientific article (publication date: February 2015)

The Impact of Positive Resection Margins on Survival and Recurrence Following Resection and Adjuvant Chemotherapy for Pancreatic Ductal Adenocarcinoma.

scientific article published on 24 October 2017

The Importance of Aquaporin 1 in Pancreatitis and Its Relation to the CFTR Cl Channel

scientific article published on 12 July 2018

The PI3K inhibitor copanlisib synergizes with sorafenib to induce cell death in hepatocellular carcinoma

The anti-inflammasome effect of lactate and the lactate GPR81-receptor in pancreatic and liver inflammation

scientific article published on 26 April 2014

The benefits of diagnostic ERCP in autoimmune pancreatitis ⬇️

scientific article published on February 11, 2011

The calcium binding protein S100A9 is essential for pancreatic leukocyte infiltration and induces disruption of cell-cell contacts

scientific article published in August 2008

The combined effects of alcohol consumption and body mass index on hepatic steatosis in a general population sample of European men and women.

scientific article published on 15 January 2015

The effect of oral pancreatic enzyme supplementation on the course and outcome of acute pancreatitis: a randomized, double-blind parallel-group study

scientific article

The impact of diabetes mellitus on survival following resection and adjuvant chemotherapy for pancreatic cancer

scientific article

The number of tandem repeats in the carboxyl-ester lipase (CEL) gene as a risk factor in alcoholic and idiopathic chronic pancreatitis

article

The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation.

scientific article

The value of sorafenib trough levels in patients with advanced hepatocellular carcinoma - a substudy of the SORAMIC trial

scientific article published on 05 May 2020

Toll-like receptor 4 polymorphisms in German and US patients are not associated with occurrence or severity of acute pancreatitis

article

Treatment of severe neurological deficits with IgG depletion through immunoadsorption in patients with Escherichia coli O104:H4-associated haemolytic uraemic syndrome: a prospective trial

scientific article

Trypsin reduces pancreatic ductal bicarbonate secretion by inhibiting CFTR Cl⁻ channels and luminal anion exchangers.

scientific article

Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice

scientific article published on 5 April 2012

Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer.

scientific article published on 12 May 2016

Ubiquitin ligases of the N-end rule pathway: assessment of mutations in UBR1 that cause the Johanson-Blizzard syndrome

scientific article

United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU).

scientific article published on 16 January 2017

Up-regulation, nuclear import, and tumor growth stimulation of the adhesion protein p120 in pancreatic cancer

scientific article published in April 2003

Why is one arm stronger than two arms? IgG4 antibodies in IgG4-related autoimmune pancreatitis

scientific article published on 21 April 2016

[Autoimmune pancreatitis].

scientific article

[Endoscopic and surgical treatment of chronic pancreatitis]

scientific article published on 01 March 2019

[Gastrointestinal innovations]

scientific article published on 01 November 2018

[Pancreatic Cancer in the Year 2018 - Room for Precision Medicine?]

scientific article published on 30 July 2018

[S2k-guideline Helicobacter pylori and gastroduodenal ulcer disease]

scientific article published on 01 April 2016

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