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List of works by Stanley J Szefler

A comparison of the clinical characteristics of children and adults with severe asthma

scientific article

A conceptual framework for pharmacodynamic genome-wide association studies in pharmacogenomics

scientific article

A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes

scientific article

A phase III randomized controlled trial of tiotropium add-on therapy in children with severe symptomatic asthma

scientific article published on 9 February 2017

A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids

scientific article

A summary of the new GINA strategy: a roadmap to asthma control

scientific article (publication date: September 2015)

A trial of clarithromycin for the treatment of suboptimally controlled asthma

scientific article published on October 1, 2010

A worldwide charter for all children with asthma

scientific article published on 06 March 2020

Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma

scientific article published on August 2016

Achieving asthma control in the inner city: do the National Institutes of Health Asthma Guidelines really work?

scientific article published on March 2010

Adding LABAs to Inhaled Glucocorticoids for Asthma

scientific article published on September 29, 2011

Addressing the risk domain in the long-term management of pediatric asthma

scientific article published on 16 November 2019

Adherence to inhaled corticosteroids: An ancillary study of the Childhood Asthma Management Program clinical trial

scientific article published on November 21, 2011

Advances in adult and pediatric asthma

scientific article published on March 2004

Advances in asthma 2015: Across the lifespan

scientific article

Advances in asthma in 2016: Designing individualized approaches to management

scientific article

Advances in childhood asthma: hygiene hypothesis, natural history, and management

scientific article

Advances in pediatric and adult asthma

scientific article

Advances in pediatric asthma 2006.

scientific article published on 30 January 2007

Advances in pediatric asthma in 2007.

scientific article published on 30 January 2008

Advances in pediatric asthma in 2008: where do we go now?

scientific article published on January 2009

Advances in pediatric asthma in 2009: gaining control of childhood asthma

scientific article published on January 2010

Advances in pediatric asthma in 2010: Addressing the major issues

scientific article published on January 1, 2011

Advances in pediatric asthma in 2011: Moving forward

scientific article published on January 1, 2012

Advances in pediatric asthma in 2012: Moving toward asthma prevention

scientific article published on November 27, 2012

Advances in pediatric asthma in 2013: coordinating asthma care

scientific article published on March 2014

Advances in pediatric asthma in 2014: Moving toward a population health perspective

scientific article published on 30 January 2015

Advancing asthma care: The glass is only half full!

scientific article published on July 27, 2011

Airway remodeling: therapeutic target or not?

scientific article published in April 2005

Airway tissue mast cells in persistent asthma: predictor of treatment failure when patients discontinue inhaled corticosteroids

scientific article

Allergy, total serum immunoglobulin E, and airflow in children and adolescents in TENOR.

scientific article published in December 2010

Altering the course of asthma: Introduction

scientific article

American Thoracic Society and National Heart, Lung, and Blood Institute Implementation Research Workshop Report

scientific article

An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice

scientific article published on July 2009

Approaching Current and New Drug Therapies for Pediatric Asthma

scientific article published in December 2017

Assessment of asthma control and asthma exacerbations in the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) observational cohort

scientific article

Asthma Management for Children: Risk Identification and Prevention

scientific article

Asthma across the ages: knowledge gaps in childhood asthma

scientific article

Asthma across the lifespan: Time for a paradigm shift

scientific article published on 05 April 2018

Asthma control, adiposity, and adipokines among inner-city adolescents

scientific article published on March 2010

Asthma exacerbations: putting a lid on the volcano

scientific article published in October 2008

Asthma morbidity among inner-city adolescents receiving guidelines-based therapy: role of predictors in the setting of high adherence

scientific article published on 16 July 2009

Asthma outcomes: biomarkers

scientific article

Atopic characteristics of children with recurrent wheezing at high risk for the development of childhood asthma

scientific article published in December 2004

Author's response

scientific article published on 01 August 2017

Azithromycin or montelukast as inhaled corticosteroid-sparing agents in moderate-to-severe childhood asthma study

scientific article published on 25 October 2008

Baseline characteristics of patients enrolled in EXCELS: a cohort study

scientific article published in September 2009

Bringing Technology to Day-to-Day Asthma Management

scientific article published on 01 August 2018

Bronchodilation and bronchoconstriction: predictors of future lung function in childhood asthma

scientific article published on 27 April 2006

Budesonide inhalation suspension versus montelukast in children aged 2 to 4 years with mild persistent asthma

scientific article published on 8 November 2012

Budesonide inhalation suspension: a nebulized corticosteroid for persistent asthma

scientific article

Building Bridges for Asthma Care Program: A School-Centered Program Connecting Schools, Families, and Community Health-Care Providers

article

Building school health partnerships to improve pediatric asthma care: the school-based asthma management program

scientific article published on 7 February 2017

Can we predict fall asthma exacerbations? Validation of the seasonal asthma exacerbation index

scientific article published on 23 February 2017

Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study in moderate to severe asthma

scientific article published on 14 September 2016

Challenges in managing difficult-to-treat asthma in children: Stop, look, and listen

scientific article published on 11 November 2019

Change in FEV and FeNO measurements as predictors of future asthma outcomes in children

scientific article published on 22 October 2018

Characterization of within-subject responses to fluticasone and montelukast in childhood asthma

scientific article

Childhood asthma clusters and response to therapy in clinical trials

scientific article published on 15 October 2013

Childhood asthma: new insights into management

scientific article

Chronotherapy of asthma with inhaled steroids: The effect of dosage timing on drug efficacy

scientific article published on 01 June 1995

Ciclesonide, a novel inhaled steroid, does not affect hypothalamic-pituitary-adrenal axis function in patients with moderate-to-severe persistent asthma

scientific article

Clinical predictors and outcomes of consistent bronchodilator response in the childhood asthma management program

scientific article

Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma

scientific article published on 14 September 2006

Commentary: Treating Pediatric Asthma According Guidelines

Comparative study of budesonide inhalation suspension and montelukast in young children with mild persistent asthma

scientific article published in November 2007

Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial

scientific article published on September 2012

Controlling the Risk Domain in Pediatric Asthma through Personalized Care

scientific article published on 10 February 2018

Correlates of household smoking bans in low-income families of children with and without asthma

scientific article published in March 2008

Corticosteroid therapy in asthma: predictors of responsiveness

scientific article

Cost-effectiveness analysis of fluticasone versus montelukast in children with mild-to-moderate persistent asthma in the Pediatric Asthma Controller Trial

scientific article

Cost-effectiveness and comparative effectiveness of biologic therapy for asthma: To biologic or not to biologic?

scientific article published on 28 January 2019

Creating District Readiness for Implementing Evidence-Based School-Centered Asthma Programs: Denver Public Schools as a Case Study

scientific article published on 28 January 2016

Creation and implementation of SAMPRO™: A school-based asthma management program

scientific article

Current State and Future of Biologic Therapies in the Treatment of Asthma in Children

Current and future management of the young child with early onset wheezing

scientific article published on 13 January 2017

Current application of exhaled nitric oxide in clinical practice

scientific article published on 21 September 2016

Current concepts in asthma treatment in children

scientific article published on June 2004

DNA Methylation Changes in Nasal Epithelia Are Associated with Allergic Asthma in the Inner City

scientific article published on March 2016

DNA methylation and childhood asthma in the inner city

scientific article published on 11 March 2015

Daily or intermittent budesonide in preschool children with recurrent wheezing

scientific article published on November 2011

Daily versus as-needed corticosteroids for mild persistent asthma

scientific article published in April 2005

Defining asthma phenotypes: Focusing the picture

scientific article published on 01 November 2010

Developing, Implementing, and Evaluating a School-Centered Asthma Program: Step-Up Asthma Program

scientific article published on 7 June 2016

Development and validation of the Composite Asthma Severity Index--an outcome measure for use in children and adolescents

scientific article published on 12 January 2012

Does access to care equal asthma control in school-age children?

scientific article published on 12 July 2009

Does inhaled steroid therapy help emerging asthma in early childhood?

scientific article published on 2 August 2017

Dr Elliot F. Ellis: Initiating personalized asthma management in children

scientific article published on 11 May 2018

Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial

scientific article

Economic burden of impairment in children with severe or difficult-to-treat asthma

scientific article published on 2 June 2011

Eczema and race as combined determinants for differential response to step-up asthma therapy

scientific article

Effect of asthma therapies on the natural course of asthma

scientific article published on 27 October 2016

Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial

scientific article

Effects of Omalizumab on Rhinovirus Infections, Illnesses and Exacerbations of Asthma

scientific article

Efficacy and Safety of Tiotropium in Children and Adolescents

scientific article published on 24 January 2018

Episodic use of an inhaled corticosteroid or leukotriene receptor antagonist in preschool children with moderate-to-severe intermittent wheezing

scientific article published on 30 October 2008

Erratum to: A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids

scientific article published on 20 October 2015

Establishing school-centered asthma programs

scientific article published in December 2014

Evaluation of the National Heart, Lung, and Blood Institute guidelines impairment domain for classifying asthma control and predicting asthma exacerbations

scientific article published on February 2012

Evolution of Asthma Self-Management Programs in Adolescents: From the Crisis Plan to Facebook

scientific article published on 10 October 2016

Examining causes of the urban (inner city) asthma epidemic: Implementing new management strategies

scientific article published on January 2016

Experimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings

scientific article published on 14 April 2015

Factors associated with asthma exacerbations during a long-term clinical trial of controller medications in children

scientific article

Fluticasone propionate plasma concentration and systemic effect: effect of delivery device and duration of administration

scientific article

Forced expiratory flow between 25% and 75% of vital capacity and FEV1/forced vital capacity ratio in relation to clinical and physiological parameters in asthmatic children with normal FEV1 values

scientific article

Future Research Directions in Asthma. An NHLBI Working Group Report

scientific article

Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids

scientific journal article

Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma

scientific article published on July 2016

Genome-wide Association Identifies the T Gene as a Novel Asthma Pharmacogenetic Locus

scientific article published on April 26, 2012

Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene

scientific article

Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients

scientific article published on 28 March 2013

Genome-wide association study of short-acting β2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3.

scientific article

Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma

scientific article published on 26 September 2011

Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone

scientific article published on August 4, 2011

Growth, systemic safety, and efficacy during 1 year of asthma treatment with different beclomethasone dipropionate formulations: an open-label, randomized comparison of extrafine and conventional aerosols in children

scientific article published in June 2002

Histopathology of severe childhood asthma: a case series

scientific article published in July 2003

ITGB5 and AGFG1 variants are associated with severity of airway responsiveness

scientific article

Identifying the child in need of asthma therapy

scientific article

Impact of Age and Sex on Response to Asthma Therapy

scientific article

Impact of a digital health intervention on asthma resource utilization

article

Improving the global diagnosis and management of asthma in children.

scientific article published on 14 May 2018

Impulse oscillometry versus spirometry in a long-term study of controller therapy for pediatric asthma

scientific article

In lasting tribute: Elliot F. Ellis, MD, 1929-2014.

scientific article

Incidence of malignancy in patients with moderate-to-severe asthma treated with or without omalizumab

scientific article published on 27 March 2014

Individualized therapy for persistent asthma in young children

scientific article

Individualizing asthma therapy: application of biomarkers

scientific article published on January 2008

Inhaled corticosteroids in lung diseases

scientific article published on April 2013

Inhaled corticosteroids: Ocular safety and the hypothalamic-pituitary-adrenal axis

scientific article published in December 2016

Inhaled corticosteroids: past lessons and future issues

scientific article published on September 2003

Inhaled steroids: are they all created equal?

scientific article published in August 2002

Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene

scientific article (publication date: 2013)

Intermittent steroid inhalation for the treatment of childhood asthma

scientific article

Introduction to the 58th Annual Thomas L. Petty Aspen Lung Conference: Asthma 2015: Mechanisms to Personalized Medicine

scientific article published on March 2016

Is it time to revise the asthma guidelines?

scientific article

Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study

scientific article

Key observations from the NHLBI Asthma Clinical Research Network

scientific article

Lessons learned from variation in response to therapy in clinical trials

scientific article

Leveraging Partnerships: Families, Schools, and Providers Working Together to Improve Asthma Management

scientific article

Long-term budesonide or nedocromil treatment, once discontinued, does not alter the course of mild to moderate asthma in children and adolescents

scientific article

Long-term effects of budesonide or nedocromil in children with asthma.

scientific article

Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial

scientific article

Managing asthma and allergies in schools: an opportunity to coordinate health care

scientific article published on 12 July 2009

Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes

scientific article

Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma

scientific article published on 14 March 2015

Measuring adherence with the Doser CT in children with asthma

scientific article published in September 2004

Medication Labeling for Children: Where is it Going?

article by Stanley J Szefler published August 2002 in Journal of Pediatric Gastroenterology and Nutrition

Medications as asthma triggers

scientific article (publication date: February 2005)

Minimizing attrition in a long-term clinical trial of pediatric asthma

scientific article published in August 2003

Monitoring and adherence in asthma management

scientific article published on 21 January 2015

Monitoring asthma in childhood: symptoms, exacerbations and quality of life

scientific article published on June 2015

Monitoring asthma in children

scientific article

Montelukast for respiratory syncytial virus bronchiolitis: significant effect or provocative findings?

scientific article

More Than a Decade Follow-up in Severe or Difficult-to-Treat Asthma: TENOR II.

scientific article published on 07 August 2017

Most nocturnal asthma symptoms occur outside of exacerbations and associate with morbidity

scientific article

Nebulized budesonide inhalation suspension compared with cromolyn sodium nebulizer solution for asthma in young children: results of a randomized outcomes trial

scientific article published in May 2002

New and future strategies to improve asthma control in children

scientific article published on 25 August 2015

New insights into asthma pathogenesis and treatment

scientific article published on 11 August 2011

No dose effect observed with chronic fluticasone propionate on growth velocity in children

scientific article published on 23 September 2020

Nocturnal awakening caused by asthma in children with mild-to-moderate asthma in the childhood asthma management program

scientific article

Omalizumab in children with uncontrolled allergic asthma: Review of clinical trial and real-world experience

scientific article published on May 2017

P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy

scientific article published on 9 November 2012

Patient characteristics associated with improved outcomes with use of an inhaled corticosteroid in preschool children at risk for asthma

scientific article

Pediatric asthma - moving ahead faster than ever

scientific article published in April 2017

Pediatric asthma: an approach to pharmacogenetics analysis

scientific article

Personalised medicine for asthma management in pregnancy

scientific article published on September 10, 2011

Personalized medicine in children with asthma

scientific article

Phenotypic predictors of long-term response to inhaled corticosteroid and leukotriene modifier therapies in pediatric asthma

scientific article published on 03 January 2009

Predictors for asthma at age 7 years for low-income children enrolled in the Childhood Asthma Prevention Study

scientific article published on October 2012

Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma

scientific article published on 29 September 2013

Predictors of poor response during asthma therapy differ with definition of outcome

scientific article published on August 2009

Predictors of remitting, periodic, and persistent childhood asthma

scientific article

Predictors of response to tiotropium versus salmeterol in asthmatic adults

scientific article published on 29 September 2013

Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations

scientific article

Prevalence of asthma-like symptoms in young children

article

Proceedings of the 2017 WAO Symposium on Hot Topics in Allergy: Pediatric & Regulatory Aspects: Rome, Italy/Vatican City. 27-29 April 2017.

scientific article published on 16 November 2017

Progression of asthma in childhood.

scientific article published in April 2005

Progression of asthma measured by lung function in the childhood asthma management program

scientific article published on 17 March 2004

Race is associated with differences in airway inflammation in patients with asthma

scientific article

Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children

scientific article

Reassessment of omalizumab-dosing strategies and pharmacodynamics in inner-city children and adolescents

scientific article

Recent asthma exacerbations predict future exacerbations in children with severe or difficult-to-treat asthma

scientific article published on November 2009

Relations between exhaled nitric oxide and measures of disease activity among children with mild-to-moderate asthma

scientific article published in May 2003

Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in children

scientific article published in November 2003

Reply

scientific article published on 11 October 2018

Reply

scientific article published on 3 August 2017

Reply to 'Can a better patient phenotyping predict the efficacy of tiotropium in asthmatic adolescents?'

scientific article published on 11 April 2017

Reply: To PMID 24290281.

scientific article published on 29 April 2014

Response profiles to fluticasone and montelukast in mild-to-moderate persistent childhood asthma

scientific article

Risk-benefit value of inhaled glucocorticoids: a pharmacokinetic/pharmacodynamic perspective

scientific article published on January 2004

Role of budesonide as maintenance therapy for children with asthma

scientific article

Safety and application of induced sputum analysis in childhood asthma

scientific article published in September 2004

Safety and efficacy of tiotropium in children aged 1-5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial

scientific article published on 17 January 2018

Safety of Adding Salmeterol to Fluticasone Propionate in Children with Asthma

scientific article published in September 2016

Safety profile of budesonide inhalation suspension in the pediatric population: worldwide experience

scientific article published in July 2004

Seasonal risk factors for asthma exacerbations among inner-city children

scientific article published on 18 March 2015

Seasonal variation in asthma exacerbations in the AUSTRI and VESTRI studies

Severe Asthma in Pediatric Patients. Pathophysiology and Unmet Needs

scientific article

Significant variability in response to inhaled corticosteroids for persistent asthma

scientific article published in March 2002

Single-dose pharmacokinetics of roflumilast in children and adolescents

scientific article published on 28 May 2008

Sleep duration, sleep hygiene, and insomnia in adolescents with asthma

scientific article

Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma

scientific article published on 4 January 2007

Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids

scientific article

Stakeholder Perspectives on Optimizing Communication in a School-Centered Asthma Program

scientific article published in December 2017

Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids

scientific article

Steroid therapy for asthma in children

scientific article published on June 2007

Steroid-unresponsive asthma

scientific article published in August 2002

Switching from conventional to extrafine aerosol beclomethasone dipropionate therapy in children: a 6-month, open- label, randomized trial

scientific article

Systematic review of the evidence regarding potential complications of inhaled corticosteroid use in asthma: collaboration of American College of Chest Physicians, American Academy of Allergy, Asthma, and Immunology, and American College of Allergy,

scientific article

Systemic effect comparisons of six inhaled corticosteroid preparations

scientific article

The Aerocrine exhaled nitric oxide monitoring system NIOX is cleared by the US Food and Drug Administration for monitoring therapy in asthma

scientific article published in November 2004

The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial

scientific article

The Prevention of Early Asthma in Kids study: design, rationale and methods for the Childhood Asthma Research and Education network

scientific article

The association between vitamin D status and the rate of exacerbations requiring oral corticosteroids in preschool children with recurrent wheezing

scientific article

The impact of self-identified race on epidemiologic studies of gene expression

scientific article published on February 2011

The long-acting β-adrenergic agonist controversy in asthma: Troublesome times!

scientific article published on 01 December 2012

The nasal methylome and childhood atopic asthma

scientific article published on 13 October 2016

The natural history of asthma and early intervention

scientific article

The need for pediatric studies of allergy and asthma medications

scientific article published on November 1, 2003

The pediatric asthma yardstick: Practical recommendations for a sustained step-up in asthma therapy for children with inadequately controlled asthma

article by Bradley E Chipps et al published June 2018 in Annals of Allergy, Asthma & Immunology

Tiotropium Is Efficacious in 6- to 17-Year-Olds with Asthma, Independent of T2 Phenotype

scientific article published on 25 March 2019

Tiotropium add-on therapy in adolescents with moderate asthma: A 1-year randomized controlled trial

scientific article published on 5 March 2016

Tiotropium add-on therapy is safe and reduces seasonal worsening in paediatric asthma patients.

scientific article published on 13 June 2019

Tiotropium bromide step-up therapy for adults with uncontrolled asthma

scientific article

Tiotropium for the treatment of asthma in adolescents

scientific article published on 21 January 2017

Understanding mild persistent asthma in children: the next frontier

scientific article

Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma

scientific article published on September 1, 2010

Use of Oral Corticosteroids in the Wheezy Toddler

scientific article published on 29 June 2018

Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial

scientific article published on 14 February 2011

Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial

scientific article published in October 2004

What is a clinically meaningful change in exhaled nitric oxide for children with asthma?

scientific article published on 07 January 2020

Where does worsening asthma end and an asthma exacerbation begin?

scientific article published on 22 November 2018

beta-Adrenergic receptor polymorphisms and response to salmeterol

scientific article published on December 2005