Search filters

List of works by Raul Andino

A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability

scientific article published on 01 October 2018

A defective viral genome strategy elicits broad protective immunity against respiratory viruses

scientific article published on 18 November 2021

A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus.

scientific article

An RNA element at the 5'-end of the poliovirus genome functions as a general promoter for RNA synthesis

scientific article

An enhanced single base extension technique for the analysis of complex viral populations ⬇️

scientific article

Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

scientific article published on 17 November 2020

Antiviral adaptive immunity and tolerance in the mosquito Aedes aegyti

Antiviral immunity in Drosophila requires systemic RNA interference spread

scientific article published on 08 February 2009

Characterization of Viral Populations by Using Circular Sequencing

scientific article

Circulating Immune Cells Mediate a Systemic RNAi-Based Adaptive Antiviral Response in Drosophila

scientific article published on April 2017

Closing the gap: the challenges in converging theoretical, computational, experimental and real-life studies in virus evolution

scientific article

Codon usage determines the mutational robustness, evolutionary capacity, and virulence of an RNA virus

scientific article

Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis

scientific article published on 01 December 2018

Comparative evaluation of prophylactic SIV vaccination modalities administered to the oral cavity

scientific article published on 22 September 2020

Control of RNA viruses in mosquito cells through the acquisition of vDNA and endogenous viral elements

scientific article published on 17 October 2019

Costs and benefits of mutational robustness in RNA viruses

scientific article

Cotranslational prolyl hydroxylation is essential for flavivirus biogenesis

scientific article published on 18 August 2021

Cricket paralysis virus antagonizes Argonaute 2 to modulate antiviral defense in Drosophila

scientific article

Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen

scientific article

Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection

scientific article published on 11 November 2015

Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers

scientific article published on 28 September 2021

Development of a new oral poliovirus vaccine for the eradication end game using codon deoptimization

scientific article published on 20 March 2020

Editorial overview: Viral pathogenesis: Strategies for virus survival - Acute versus persistent infections

scientific article published in April 2017

Engineering attenuated virus vaccines by controlling replication fidelity

scientific article published on 3 February 2008

Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to Virulence

scientific article published on 10 April 2020

Enterovirus pathogenesis requires the host methyltransferase SETD3

scientific article published on 16 September 2019

Epidemics as an adaptive driving force determining lifespan setpoints

scientific article published on 10 July 2020

Erratum: corrigendum: Short interfering RNA confers intracellular antiviral immunity in human cells

scientific article published in Nature

Ethacridine inhibits SARS-CoV-2 by inactivating viral particles

scientific article

Ethacridine inhibits SARS-CoV-2 by inactivating viral particles in cellular models

scientific article published on 28 October 2020

Evaluation and validation of next-generation sequencing to support lot release for a novel type 2 oral poliovirus vaccine

scientific article published on 11 June 2021

Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance

scientific article published on January 2007

Experimental and mathematical insights on the competition between poliovirus and a defective interfering genome

article

Experimentally guided models reveal replication principles that shape the mutation distribution of RNA viruses

scientific article

Exploring RNA virus replication in Xenopus oocytes

scientific article published in January 2006

Exploring the fitness landscape of an RNA virus by using a universal barcode microarray

scientific article

Extending the Family of UNCG-like Tetraloop Motifs: NMR Structure of a CACG Tetraloop from Coxsackievirus B3 ⬇️

scientific article (publication date: 22 April 2003)

Generation of a conditionally replicating adenovirus based on targeted destruction of E1A mRNA by a cell type-specific MicroRNA.

scientific article

Global RNA structure analysis of poliovirus identifies a conserved RNA structure involved in viral replication and infectivity

scientific article published on 21 August 2013

Harnessing endogenous miRNAs to control virus tissue tropism as a strategy for developing attenuated virus vaccines

scientific article published on September 2008

High-throughput DNA sequencing errors are reduced by orders of magnitude using circle sequencing

scientific article

Hsp90 dictates viral sequence space by balancing the evolutionary tradeoffs between protein stability, aggregation and translation rate

article published in 2017

Hsp90 inhibitors exhibit resistance-free antiviral activity against respiratory syncytial virus

scientific article

Hsp90 shapes protein and RNA evolution to balance trade-offs between protein stability and aggregation.

scientific article

Identification and manipulation of the molecular determinants influencing poliovirus recombination

scientific article

Implications of high RNA virus mutation rates: lethal mutagenesis and the antiviral drug ribavirin

scientific article

Library preparation for highly accurate population sequencing of RNA viruses

scientific article

Manganese-Dependent Polioviruses Caused by Mutations within the Viral Polymerase ⬇️

scientific article published on May 1, 2003

Mapping Attenuation Determinants in Enterovirus-D68

scientific article published on 08 August 2020

Mapping the Evolutionary Potential of RNA Viruses.

scientific article published in April 2018

Mechanisms and Concepts in RNA Virus Population Dynamics and Evolution

article

Metagenomic sequencing of stool samples in Bangladeshi infants: virome association with poliovirus shedding after oral poliovirus vaccination

scientific article published on 21 September 2020

Mucosal immunization of cynomolgus macaques with two serotypes of live poliovirus vectors expressing simian immunodeficiency virus antigens: stimulation of humoral, mucosal, and cellular immunity

scientific article

Mutational and fitness landscapes of an RNA virus revealed through population sequencing

scientific article

NMR structures of loop B RNAs from the stem-loop IV domain of the enterovirus internal ribosome entry site: a single C to U substitution drastically changes the shape and flexibility of RNA.

scientific article

Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants

Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants

scientific article published on 18 March 2022

Non-specific dsRNA-mediated antiviral response in the honey bee.

scientific article

Nucleic acid-based immune system: the antiviral potential of mammalian RNA silencing

scientific article

Pathogenic Events in a Nonhuman Primate Model of Oral Poliovirus Infection Leading to Paralytic Poliomyelitis.

scientific article published on 29 March 2017

Poliovirus RNA-dependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and B

scientific article (publication date: 18 August 2000)

Poliovirus escape from RNA interference: short interfering RNA-target recognition and implications for therapeutic approaches

scientific article published on January 2005

Poliovirus infection blocks ERGIC-to-Golgi trafficking and induces microtubule-dependent disruption of the Golgi complex.

scientific article

Poliovirus intrahost evolution is required to overcome tissue-specific innate immune responses.

scientific article

Poliovirus pathogenesis in a new poliovirus receptor transgenic mouse model: age-dependent paralysis and a mucosal route of infection

scientific article

Poliovirus vaccine strains as mucosal vaccine vectors and their potential use to develop an AIDS vaccine.

scientific article

Poliovirus: generation and characterization of mutants

scientific article

Poliovirus: generation, quantification, propagation, purification, and storage

scientific article published on January 2013

Polyadenylation of genomic RNA and initiation of antigenomic RNA in a positive-strand RNA virus are controlled by the same cis-element

scientific article

Protection against simian immunodeficiency virus vaginal challenge by using Sabin poliovirus vectors

scientific article

Quasispecies theory and the behavior of RNA viruses

scientific article

RNA Recombination Enhances Adaptability and Is Required for Virus Spread and Virulence

scientific article

RNA Recombination Enhances Adaptability and Is Required for Virus Spread and Virulence.

scientific article

RNA interference-mediated intrinsic antiviral immunity in invertebrates.

scientific article published on January 2013

RNA silencing in viral infections: insights from poliovirus

scientific article published on June 2004

RNA structure analysis of viruses using SHAPE

scientific article

RNA virus error catastrophe: direct molecular test by using ribavirin

scientific article

RNA virus population diversity, an optimum for maximal fitness and virulence

scientific article

RNAi puts a lid on virus replication

scientific article published in June 2003

Rapid evolution of virus sequences in intrinsically disordered protein regions

scientific article

Rationalizing the development of live attenuated virus vaccines

scientific article

Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase

scientific article

Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implications

scientific article

Ribavirin's antiviral mechanism of action: lethal mutagenesis?

scientific article

SARS-CoV-2 Nsp1 cooperates with initiation factors EIF1 and 1A to selectively enhance translation of viral RNA

scientific article published in 2024

SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment

scientific article

Short interfering RNA confers intracellular antiviral immunity in human cells

scientific article published on 26 June 2002

Single-cell analysis uncovers extensive biological noise in poliovirus replication

scientific article published on 19 March 2014

Slicer activity in Drosophila melanogaster S2 extract

scientific article published on January 2011

Solution structure of a consensus stem-loop D RNA domain that plays important roles in regulating translation and replication in enteroviruses and rhinoviruses

scientific article published in September 2004

Species-Specific Evolution of Ebola Virus during Replication in Human and Bat Cells

scientific article published on 01 August 2020

Specific recognition of the C-rich strand of human telomeric DNA and the RNA template of human telomerase by the first KH domain of human poly(C)-binding protein-2.

scientific article

StralSV: assessment of sequence variability within similar 3D structures and application to polio RNA-dependent RNA polymerase

scientific article

Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis

scientific article published on January 2006

Studies towards the potential of poliovirus as a vector for the expression of HPV 16 virus-like-particles.

scientific article

Temporal analysis of the honey bee microbiome reveals four novel viruses and seasonal prevalence of known viruses, Nosema, and Crithidia

scientific article published in 2011

The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing

scientific article (publication date: August 2016)

The Diversity, Structure, and Function of Heritable Adaptive Immunity Sequences in the Aedes aegypti Genome

scientific article published on 2 November 2017

The Evolutionary Pathway to Virulence of an RNA Virus

scientific article published on March 2017

The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster

scientific article

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

scientific article published in December 2000

The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing

scientific article published on 23 July 2006

The poliovirus 2C cis-acting replication element-mediated uridylylation of VPg is not required for synthesis of negative-sense genomes

scientific article published in September 2003

The poliovirus replication machinery can escape inhibition by an antiviral drug that targets a host cell protein

scientific article published on April 2004

The role of mutational robustness in RNA virus evolution

scientific article published on 25 March 2013

The safety and immunogenicity of two novel live attenuated monovalent (serotype 2) oral poliovirus vaccines in healthy adults: a double-blind, single-centre phase 1 study

scientific article published on 04 June 2019

The silent treatment: RNAi as a defense against virus infection in mammals

scientific article

Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation

scientific article

Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant

article by Xianding Deng et al published 24 June 2021 in Cell

Use of host-like peptide motifs in viral proteins is a prevalent strategy in host-virus interactions

scientific article published on 29 May 2014

Variability in viral pathogenesis: modeling the dynamic of acute and persistent infections

scientific article

Viral Evolution

scientific article

Viral Generated Inter-Organelle Contacts Redirect Lipid Flux for Genome Replication

scientific article published on 13 June 2019

Viral polymerases

scientific article published on 7 February 2017

Viral quasispecies

scientific article published on 29 March 2015

Zika Virus Dependence on Host Hsp70 Provides a Protective Strategy against Infection and Disease

scientific article published on 01 January 2019

miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts

scientific article

Paulina is supported by:

About Paulina

Help