List of works - Ari Helenius

A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes

scientific article (publication date: 23 March 2016)

Architecture of respiratory syncytial virus revealed by electron cryotomography

scientific article

Assembly and trafficking of caveolar domains in the cell: caveolae as stable, cargo-triggered, vesicular transporters

scientific article

Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation.

scientific article

Caveolin-Stabilized Membrane Domains as Multifunctional Transport and Sorting Devices in Endocytic Membrane Traffic

Clathrin- and caveolin-1-independent endocytosis: entry of simian virus 40 into cells devoid of caveolae

scientific article

Cullin-3 regulates late endosome maturation.

scientific article published on 4 January 2012

ERp57 is a multifunctional thiol-disulfide oxidoreductase

scientific article (publication date: 30 April 2004)

Echovirus 1 endocytosis into caveosomes requires lipid rafts, dynamin II, and signaling events.

scientific article

Effects of organelle shape on fluorescence recovery after photobleaching

scientific article

Endocytosis of viruses and bacteria

scientific article

Endocytosis via caveolae

scientific article

Endosome maturation ⬇️

scientific article published on August 31, 2011

Entry of human papillomavirus type 16 by actin-dependent, clathrin- and lipid raft-independent endocytosis

scientific article (publication date: 2012)

Folding and dimerization of tick-borne encephalitis virus envelope proteins prM and E in the endoplasmic reticulum

scientific article

Folding, quality control, and secretion of pancreatic ribonuclease in live cells

scientific article

Genome-wide small interfering RNA screens reveal VAMP3 as a novel host factor required for Uukuniemi virus late penetration

scientific article

Gulping rather than sipping: macropinocytosis as a way of virus entry ⬇️

scientific article published on June 29, 2012

High-content analysis of sequential events during the early phase of influenza A virus infection

scientific article (publication date: 2013)

Histone Deacetylase 8 Is Required for Centrosome Cohesion and Influenza A Virus Entry ⬇️

scientific article (publication date: October 2011)

Host cell entry of respiratory syncytial virus involves macropinocytosis followed by proteolytic activation of the F protein

scientific article

How Viruses Enter Animal Cells

scientific article

Human papillomavirus type 16 entry: retrograde cell surface transport along actin-rich protrusions

scientific article (publication date: 2008)

Insider information: what viruses tell us about endocytosis

scientific article

Interactions of substrate with calreticulin, an endoplasmic reticulum chaperone

scientific article

Intracellular Assembly and Secretion of Recombinant Subviral Particles from Tick-Borne Encephalitis Virus

scientific article

Large scale RNAi reveals the requirement of nuclear envelope breakdown for nuclear import of human papillomaviruses

scientific article

Late-penetrating viruses

scientific article published on 12 June 2011

Lipid-mediated endocytosis.

scientific article

Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae

scientific article

Minor folding defects trigger local modification of glycoproteins by the ER folding sensor GT

scientific article

N-glycolyl GM1 ganglioside as a receptor for simian virus 40.

scientific article published on 12 September 2007

NMR structures of 36 and 73-residue fragments of the calreticulin P-domain

scientific article

Nuclear import of hepatitis B virus capsids and release of the viral genome

scientific article published on 8 August 2003

PI3Kγ Is Critical for Dendritic Cell-Mediated CD8+ T Cell Priming and Viral Clearance during Influenza Virus Infection

scientific article (publication date: March 2016)

RNAi screening reveals proteasome- and Cullin3-dependent stages in vaccinia virus infection.

scientific article published on 19 October 2012

Rab7 associates with early endosomes to mediate sorting and transport of Semliki forest virus to late endosomes

scientific article

Role of endosomes in simian virus 40 entry and infection

scientific article

Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells

scientific article

Simultaneous analysis of large-scale RNAi screens for pathogen entry

scientific article

Single-cell analysis of population context advances RNAi screening at multiple levels

scientific article

Single-particle tracking of murine polyoma virus-like particles on live cells and artificial membranes

scientific article

Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens

scientific article

Stepwise priming by acidic pH and a high K+ concentration is required for efficient uncoating of influenza A virus cores after penetration

scientific article

TROSY-NMR reveals interaction between ERp57 and the tip of the calreticulin P-domain

scientific article

Vaccinia Virus Infection Requires Maturation of Macropinosomes

scientific article published on 06 May 2015

Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture ⬇️

scientific article published on July 26, 2011

Vaccinia virus strains use distinct forms of macropinocytosis for host-cell entry

scientific article

Virus entry by endocytosis

scientific article (publication date: 2010)

Virus entry by macropinocytosis

scientific article published on May 2009

Virus entry: open sesame

scientific article (publication date: 24 February 2006)

siRNA screen of early poxvirus genes identifies the AAA+ ATPase D5 as the virus genome-uncoating factor

scientific article

List of works by Ari Helenius

A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes

Architecture of respiratory syncytial virus revealed by electron cryotomography

Assembly and trafficking of caveolar domains in the cell: caveolae as stable, cargo-triggered, vesicular transporters

Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation.

Caveolin-Stabilized Membrane Domains as Multifunctional Transport and Sorting Devices in Endocytic Membrane Traffic

Clathrin- and caveolin-1-independent endocytosis: entry of simian virus 40 into cells devoid of caveolae

Cullin-3 regulates late endosome maturation.

ERp57 is a multifunctional thiol-disulfide oxidoreductase

Echovirus 1 endocytosis into caveosomes requires lipid rafts, dynamin II, and signaling events.

Effects of organelle shape on fluorescence recovery after photobleaching

Endocytosis of viruses and bacteria

Endocytosis via caveolae

Endosome maturation ⬇️

Entry of human papillomavirus type 16 by actin-dependent, clathrin- and lipid raft-independent endocytosis

Folding and dimerization of tick-borne encephalitis virus envelope proteins prM and E in the endoplasmic reticulum

Folding, quality control, and secretion of pancreatic ribonuclease in live cells

Genome-wide small interfering RNA screens reveal VAMP3 as a novel host factor required for Uukuniemi virus late penetration

Gulping rather than sipping: macropinocytosis as a way of virus entry ⬇️

High-content analysis of sequential events during the early phase of influenza A virus infection

Histone Deacetylase 8 Is Required for Centrosome Cohesion and Influenza A Virus Entry ⬇️

Host cell entry of respiratory syncytial virus involves macropinocytosis followed by proteolytic activation of the F protein

How Viruses Enter Animal Cells

Human papillomavirus type 16 entry: retrograde cell surface transport along actin-rich protrusions

Insider information: what viruses tell us about endocytosis

Interactions of substrate with calreticulin, an endoplasmic reticulum chaperone

Intracellular Assembly and Secretion of Recombinant Subviral Particles from Tick-Borne Encephalitis Virus

Large scale RNAi reveals the requirement of nuclear envelope breakdown for nuclear import of human papillomaviruses

Late-penetrating viruses

Lipid-mediated endocytosis.

Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae

Minor folding defects trigger local modification of glycoproteins by the ER folding sensor GT

N-glycolyl GM1 ganglioside as a receptor for simian virus 40.

NMR structures of 36 and 73-residue fragments of the calreticulin P-domain

Nuclear import of hepatitis B virus capsids and release of the viral genome

PI3Kγ Is Critical for Dendritic Cell-Mediated CD8+ T Cell Priming and Viral Clearance during Influenza Virus Infection

RNAi screening reveals proteasome- and Cullin3-dependent stages in vaccinia virus infection.

Rab7 associates with early endosomes to mediate sorting and transport of Semliki forest virus to late endosomes

Role of endosomes in simian virus 40 entry and infection

Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells

Simultaneous analysis of large-scale RNAi screens for pathogen entry

Single-cell analysis of population context advances RNAi screening at multiple levels

Single-particle tracking of murine polyoma virus-like particles on live cells and artificial membranes

Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens

Stepwise priming by acidic pH and a high K+ concentration is required for efficient uncoating of influenza A virus cores after penetration

TROSY-NMR reveals interaction between ERp57 and the tip of the calreticulin P-domain

Vaccinia Virus Infection Requires Maturation of Macropinosomes

Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture ⬇️

Vaccinia virus strains use distinct forms of macropinocytosis for host-cell entry

Virus entry by endocytosis

Virus entry by macropinocytosis

Virus entry: open sesame

siRNA screen of early poxvirus genes identifies the AAA+ ATPase D5 as the virus genome-uncoating factor