Search filters

List of works by Leonard I. Zon

A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish

scientific article

A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis

scientific article published on 7 November 2013

A Great Match ⬇️

scientific article published on June 14, 2012

A Model for Primary Melanoma of the CNS Implicates NRAS ⬇️

scientific article published on 01 April 2013

A New System for the Rapid Collection of Large Numbers of Developmentally Staged Zebrafish Embryos ⬇️

scientific article published on June 29, 2011

A Quantitative System for Studying Metastasis Using Transparent Zebrafish.

scientific article published on 17 August 2015

A Transgenic System for Rapid Magnetic Enrichment of Rare Embryonic Cells

scientific article published on 29 July 2020

A Tribute to George Stamatoyannopoulos.

scientific article published in April 2016

A chemical genetic screen for cell cycle inhibitors in zebrafish embryos

scientific article published on October 2006

A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis

scientific article

A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development.

scientific article

A comparison of non-integrating reprogramming methods

scientific article

A critical role for calponin 2 in vascular development

scientific article

A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence

scientific article published on 30 March 2009

A mutation in separase causes genome instability and increased susceptibility to epithelial cancer

scientific article published on January 2007

A network of epigenetic regulators guides developmental haematopoiesis in vivo

scientific article

A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis

scientific article

A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro

scientific article published on 12 September 2006

A splice site mutation in laminin-α2 results in a severe muscular dystrophy and growth abnormalities in zebrafish

scientific article

A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility

scientific article

A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species.

scientific article published on November 2013

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation

scientific article published on 28 January 2016

A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing.

scientific article

AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate

scientific article published on 31 January 2019

APC and colon cancer: two hits for one.

scientific article

APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development

scientific article published on 20 May 2008

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

scientific article

Advanced Zebrafish Transgenesis with Tol2 and Application for Cre/lox Recombination Experiments

scientific article published on 01 January 2011

Allan j. Erslev, m.d.: truly a great dane (1919-2003).

scientific article published in January 2004

AlphaA-crystallin expression prevents gamma-crystallin insolubility and cataract formation in the zebrafish cloche mutant lens

scientific article published on 25 May 2006

An Mll-dependent Hox program drives hematopoietic progenitor expansion

scientific journal article

An evolutionary ancient mechanism for regulation of hemoglobin expression in vertebrate red cells

scientific article published on 12 May 2020

An optical platform for cell tracking in adult zebrafish ⬇️

scientific article published on December 7, 2011

Analysis of hematopoietic development in the zebrafish.

scientific article

Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling

scientific journal article

Assaying hematopoiesis using zebrafish ⬇️

scientific article published on 02 August 2013

Attack of the fish clones

scientific article published on 01 August 2002

Author Correction: Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment

scientific article published on 01 September 2019

BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway

scientific article published in January 2008

BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis

scientific article published on 3 May 2006

Biomedicine. Love, honor, and protect (your liver).

scientific article

Blood flow: metalloproteases cut loose in primitive erythrocytes

scientific article published in July 2010

Blood on the tracks: hematopoietic stem cell-endothelial cell interactions in homing and engraftment

scientific article

CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation

scientific article published on 03 September 2020

CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development

scientific article published on 30 September 2012

CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment

scientific article published on 28 March 2017

Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia

scientific article published on 01 October 2020

Cancer and inflammation: an aspirin a day keeps the cancer at bay.

scientific article published in July 2012

Cancer genetics and drug discovery in the zebrafish

scientific article

Cancer immunotherapy: The dark side of PD-1 receptor inhibition

scientific article published on 15 November 2017

Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model

scholarly article

Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis

scientific article published on 21 May 2010

Cell stem cell

scientific article published on 01 June 2007

Chamber identity programs drive early functional partitioning of the heart.

scientific article

Characterization of immune-matched hematopoietic transplantation in zebrafish ⬇️

scientific article published on February 23, 2011

Characterization of zebrafish merlot/chablis as non-mammalian vertebrate models for severe congenital anemia due to protein 4.1 deficiency.

scientific article published in September 2002

Chemical genetic screening in the zebrafish embryo

scientific article published on 10 September 2009

Chemical screening in zebrafish for novel biological and therapeutic discovery

scientific article published on 01 January 2011

Chromatin immunoprecipitation in adult zebrafish red cells ⬇️

scientific article published on January 1, 2011

Clonal analysis of hematopoietic progenitor cells in the zebrafish ⬇️

scientific article published on March 17, 2011

Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development

scientific article

Combinatorial regulation of novel erythroid gene expression in zebrafish

scientific article published on 4 February 2008

Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits

scientific article published on 23 November 2020

Construction and application of a zebrafish array comparative genomic hybridization platform

scientific article published on February 2009

Corrigendum: Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development

scientific article

Cross-species analysis of enhancer logic using deep learning

scientific article published on 30 July 2020

DHODH modulates transcriptional elongation in the neural crest and melanoma

scientific article

DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish

scientific article

Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis

scientific article

Defining cancer stem cells by xenotransplantation in zebrafish

scientific article published on 01 January 2009

Derivation of adult stem cells during embryogenesis

scientific article published on January 2006

Development: For cloche the Bell Tolls

scientific article published on 10 October 2016

Difference in biophysical properties of cancer-initiating cells in melanoma mutated zebrafish

scientific article published on 08 April 2020

Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors.

scientific article

Distinct Roles for Matrix Metalloproteinases 2 and 9 in Embryonic Hematopoietic Stem Cell Emergence, Migration, and Niche Colonization

scientific article published on 12 April 2017

Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors

scientific article published on February 2017

Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish

scientific article

Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis

scientific article published on January 2016

EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay

scientific article

Effects of RAS on the genesis of embryonal rhabdomyosarcoma.

scientific article published on 17 May 2007

Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation

scientific article

Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors.

scientific article published on 30 May 2017

Efforts to enhance blood stem cell engraftment: Recent insights from zebrafish hematopoiesis

scientific article published on 22 August 2017

Engineering Hematopoietic Stem Cells: Lessons from Development

scientific article

Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment

scientific article

Erratum: Deficiency of glutaredoxin 5 reveals Fe–S clusters are required for vertebrate haem synthesis

journal article; published in Nature, 2005-10

Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes

scientific article published on 12 January 2019

Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes

scientific article

Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies

scientific article

Expression and mapping of duplicate neuropilin-1 and neuropilin-2 genes in developing zebrafish

scientific article published in July 2004

External signals regulate continuous transcriptional states in hematopoietic stem cells

scientific article published on 23 December 2021

Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish

scientific article

FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity

scientific article published in Journal of Biological Chemistry

Ferroportin1 is required for normal iron cycling in zebrafish

scientific article

Fish to Learn: Insights into Blood Development and Blood Disorders from Zebrafish Hematopoiesis

scientific article published on 28 March 2016

Fishing at the cellular level ⬇️

scientific article published on 01 August 2010

Fishing for answers in precision cancer medicine

scientific article published on 15 September 2017

Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence

scientific article published on 13 April 2015

Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1–induced collective directional migration and angiogenic sprouting ⬇️

scientific article published on August 30, 2012

From blood development to disease: a paradigm for clinical translation

scientific article published on 09 January 2020

From fish bowl to bedside: The power of zebrafish to unravel melanoma pathogenesis and discover new therapeutics.

scientific article published on 8 June 2017

From fish tank to bedside in cancer therapy: an interview with Leonard Zon.

scientific article published on July 2014

GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis.

scientific article published on 9 February 2016

Gain-of-function genetic alterations of G9a drive oncogenesis

scientific article published on 08 April 2020

Gene Duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a.

scientific article

Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters

scientific article published on 30 October 2007

Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies

scientific article published on 05 November 2018

Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells

scientific article

Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism

scientific article

Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration

scientific article (publication date: 20 March 2009)

Genetic suppressor screens in haploids

scientific article published on 01 January 2011

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

scientific article published on 19 December 2016

Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2.

scientific article

Happy reunion

scientific article published in Nature

Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish

scholarly article

Hematopoiesis

article from 2013

Hematopoiesis and stem cells: plasticity versus developmental heterogeneity

scientific article

Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation

scientific article published on 25 November 2011

Hematopoietic development in the zebrafish

scientific article published on January 2010

Hematopoietic gene expression profile in zebrafish kidney marrow.

scientific article published in November 2004

Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche.

scientific article published on January 2015

Hematopoietic stem cell development is dependent on blood flow.

scientific article published on May 2009

Hematopoietic stem cell fate is established by the Notch-Runx pathway

scientific article

Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression

scientific article

Hematopoietic stem cells, hematopoiesis and disease: lessons from the zebrafish model ⬇️

scientific article published on December 29, 2011

High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia

scientific article

Histocompatibility and hematopoietic transplantation in the zebrafish

scientific article

Homing sweet homing: odyssey of hematopoietic stem cells

scientific article published on December 2006

Hooked! Modeling human disease in zebrafish ⬇️

scientific article published on July 2, 2012

Human tumor genomics and zebrafish modeling identify loss as a driver of mucosal melanoma

scientific article published in Science

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells

scientific article published on 22 January 2020

Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice.

scientific article

Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

scientific article published on 23 August 2016

Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish

scientific article published on January 2016

Impact of COVID-19 Pandemic on Cancer Research

scientific article published on 08 October 2020

Improving the visibility of developmental biology: time for induction and specification

scientific article published on 16 January 2019

In situ hybridization assay-based small molecule screening in zebrafish

scientific article

In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish

scientific article

Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors

scientific article published on October 2013

Inhibition of zebrafish epidermal growth factor receptor activity results in cardiovascular defects

scientific article published in July 2003

Interaction of retinoic acid and scl controls primitive blood development

scientific article

Intestinal differentiation in zebrafish requires Cdx1b, a functional equivalent of mammalian Cdx2.

scientific article

Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal

scientific article published on May 2008

Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo size

scientific article

Isolation and characterization of runxa and runxb, zebrafish members of the runt family of transcriptional regulators

scientific article

Isolation and characterization of zebrafish NFE2.

scientific article published on 29 October 2002

Isolation and transcriptome analysis of adult zebrafish cells enriched for skeletal muscle progenitors. ⬇️

scientific article

JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia.

scientific article published on 25 June 2018

KIT Suppresses BRAFV600E-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling

scientific article

Lessons from the niche for generation and expansion of hematopoietic stem cells ⬇️

scientific article published on January 1, 2009

Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration

scientific article published on October 2011

Linking hematopoietic regeneration to developmental signaling pathways: a story of BMP and Wnt.

scientific article published on February 2012

Loci associated with skin pigmentation identified in African populations.

scientific article published on 12 October 2017

Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects

scientific article published on 01 June 2020

Long-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studies

scientific article

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

scientific article published on 24 August 2016

Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma

scientific article published on 01 June 2020

Melanocytes in development and cancer

scientific article published on January 2010

Melanocytes in development, regeneration, and cancer

scientific article published on September 2008

Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE)

scientific article

Mitochondrial function in development and disease

scientific article published in 2021

Modeling Cancer with Flies and Fish

scientific article published on 01 May 2019

Modeling Diamond Blackfan Anemia in the Zebrafish ⬇️

scientific article published on April 1, 2011

Modeling human diseases: an education in interactions and interdisciplinary approaches

scientific article published on June 2016

Modeling human hematopoietic and cardiovascular diseases in zebrafish ⬇️

scientific article published on November 1, 2003

Mutant-specific gene programs in the zebrafish

scientific article published on 12 April 2005

Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss

scientific article

Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction.

scientific article published on 3 July 2015

Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures

scientific article

Myc-induced T cell leukemia in transgenic zebrafish

scientific article published in February 2003

NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells.

scientific article

Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway.

scientific article published in March 2012

Neural crest development and craniofacial morphogenesis is coordinated by nitric oxide and histone acetylation

scientific article published on 27 March 2014

Neural crest state activation in NRAS driven melanoma, but not in NRAS-driven melanocyte expansion

scientific article published on 05 June 2018

Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish

scientific article

New waves of discovery: modeling cancer in zebrafish

scientific article published on June 2007

Newly emerging roles for prostaglandin E2 regulation of hematopoiesis and hematopoietic stem cell engraftment

scientific article published on July 2010

Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish

Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord

scientific article (publication date: 15 March 2007)

Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium

scientific article

Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish

scientific article

Of fish and men: using zebrafish to fight human diseases.

scientific article published in December 2013

Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish

scientific article

Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo

scientific article

Organogenesis--heart and blood formation from the zebrafish point of view

scientific article

PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes.

scientific article

PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo

scientific article published on 16 August 2017

PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury.

scientific article

PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation

scientific article published on 08 July 2020

Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish ⬇️

scientific article published on December 7, 2012

Piloting the zebrafish genome browser

scientific article published on 01 March 2006

Portrait of a stem cell

scientific article

Potential of zebrafish for anticancer drug screening ⬇️

scientific article published on 01 December 2008

Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models.

scientific article

Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis

scientific article published on June 2007

Prostaglandin E2: making more of your marrow

scientific article published on 03 October 2007

Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation

scientific article published on 30 August 2013

Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche

scientific article published in Nature

Purification of zebrafish erythrocytes as a means of identifying a novel regulator of haematopoiesis.

scientific article published on 19 December 2017

RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells

scientific article published on 30 March 2020

RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes.

scientific article published on 8 March 2018

Recurrent co-alteration of HDGF and SETDB1 on chromosome 1q drives cutaneous melanoma progression and poor prognosis

scientific article published on 16 October 2020

Resolving the controversy about N-cadherin and hematopoietic stem cells

scientific article published on 01 March 2010

Retro-orbital injection in adult zebrafish

scientific article published on 7 December 2009

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

scientific article (publication date: December 1994)

SPRED1 deletion confers resistance to MAPK inhibition in melanoma

scientific article published on 01 March 2021

SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization

scientific journal article

SUMO-1 protease-1 regulates gene transcription through PML

scientific journal article

Screening for melanoma resistance genes in vivo.

scientific article

Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4).

scientific article

Self-renewal and differentiation at Cell Stem Cell

scientific article published in June 2008

Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition ⬇️

scientific article published on December 12, 2012

Site-directed zebrafish transgenesis into single landing sites with the phiC31 integrase system

scientific article published on 03 July 2013

Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination

scientific article published on 14 October 2019

Small molecule screen in zebrafish and HSC expansion

scientific article

SnapShot: hematopoiesis

scientific article

Sorting zebrafish thrombocyte lineage cells with a Cd41 monoclonal antibody enriches hematopoietic stem cell activity

scientific article

Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132

scientific article published on 23 August 2018

Stem Cell Migration: A Zebrafish Model ⬇️

scientific article published on January 1, 2011

Stem cell safe harbor: the hematopoietic stem cell niche in zebrafish

scientific article published on 01 November 2018

Stem cells on a stress-busting diet ⬇️

journal article; published in Nature on 2013-02-06

Stem cells: The blood balance

scientific article published in December 2010

Stem cells: The right neighbour

scientific article published in Nature

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.

scientific article published on April 2016

Stromal cell-derived factor-1 and hematopoietic cell homing in an adult zebrafish model of hematopoietic cell transplantation

scientific article published on 26 May 2011

Structural basis for inactivation of PRC2 by G-quadruplex RNA

scientific article published on 21 September 2023

Stu Orkin is a superhero

Swimming into the future of drug discovery: in vivo chemical screens in zebrafish

scientific article

Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss

scientific article published on 30 July 2021

T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation.

scientific article

TIF1gamma controls erythroid cell fate by regulating transcription elongation

scientific article

Taking human cancer genes to the fish: a transgenic model of melanoma in zebrafish

scientific article published in January 2005

Taking the stem cell debate to the public

scientific article

Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera

scientific article published on 23 August 2007

The 'definitive' (and 'primitive') guide to zebrafish hematopoiesis

scientific article published in September 2004

The ERGonomics of hematopoietic stem cell self-renewal

scientific article published on February 2011

The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish ⬇️

scientific article published on May 21, 2013

The NOTCH pathway contributes to cell fate decision in myelopoiesis

scientific article published on 20 September 2011

The Paf1 complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors

scientific article published on 16 December 2019

The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.

scientific article

The Zon laboratory guide to positional cloning in zebrafish

scientific article published on 01 January 2004

The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis

scientific article published on 7 February 2006

The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1.

scientific article published in December 2004

The clinical potential of stem cells

scientific article

The complex cartography of stem cell commitment

scientific article

The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models

scientific article published on January 2013

The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression

scientific article published on 26 January 2018

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

scientific article

The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis

scientific article

The new age of chemical screening in zebrafish

scientific article published on 01 March 2010

The transcriptional landscape of hematopoietic stem cell ontogeny

scientific article published on November 2012

The use of zebrafish to understand immunity

scientific article published on April 2004

The zebra fish cassiopeia mutant reveals that SIL is required for mitotic spindle organization

scientific article

The zebrafish as a model organism to study development of the immune system

scientific article published on January 2003

The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies

scientific article

The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis

scientific article

The zebrafish runzel muscular dystrophy is linked to the titin gene

scientific article published on 23 June 2007

The zebrafish: a new model of T-cell and thymic development

scientific article

The zon laboratory guide to positional cloning in zebrafish

scientific article published on January 1, 2011

TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes

scientific article published on 16 November 2012

Tissue specific roles for the ribosome biogenesis factor Wdr43 in zebrafish development

scientific article published on 30 January 2014

Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling.

scientific article

TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis

scientific article (publication date: July 2015)

Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish

scientific article published on 20 April 2009

Transcription factor induction of vascular blood stem cell niches in vivo

scientific article published in 2023

Transcriptional regulation of hematopoietic stem cell development in zebrafish

scientific article

Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System

scientific article published on 09 April 2020

Transferrin-a modulates hepcidin expression in zebrafish embryos

scientific article published on December 2008

Translational research: the path for bringing discovery to patients.

scientific article published in February 2014

Transparent adult zebrafish as a tool for in vivo transplantation analysis

scientific article

Transplantation in Zebrafish ⬇️

scientific article published on January 1, 2011

Transplantation of whole kidney marrow in adult zebrafish

scientific article published on 25 February 2007

Tumor-Derived Extracellular Vesicles Breach the Intact Blood-Brain Barrier via Transcytosis

scientific article published on 10 September 2019

Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1alpha/tcf1 and hnf1beta/tcf2, abundantly expressed in liver, pancreas, gut and kidney of zebrafish

scientific article published in August 2004

Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish

scientific article

Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors

scientific article published on 17 June 2007

Understanding the regulation of vertebrate hematopoiesis and blood disorders - big lessons from a small fish

scientific article published on 12 September 2016

Unexpectedly uneven: posttransplant skeletal distribution of hematopoietic stem cell clones

scientific article published on March 2014

Use of the zebrafish system to study primitive and definitive hematopoiesis

scientific article

Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration

scientific article

Walking the walk: migration and other common themes in blood and vascular development

scientific article

Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families

scientific article

Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation and hatching

scientific article published in December 2005

Zebrafish as a cancer model system

scientific article

Zebrafish as a model for normal and malignant hematopoiesis ⬇️

scientific article published on July 1, 2011

Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma

scientific article published on 12 September 2018

Zebrafish cancer: the state of the art and the path forward

scientific article published in September 2013

Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR.

scientific article

Zebrafish models of p53 functions

scientific article

Zebrafish orthologs of human muscular dystrophy genes

scientific article

Zebrafish patient avatars in cancer biology and precision cancer therapy

scientific article published on 06 April 2020

Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis ⬇️

scientific article published on July 1, 2013

Zebrafish scl functions independently in hematopoietic and endothelial development

scientific article published in January 2005

Zebrafish slc4a2/ae2 anion exchanger: cDNA cloning, mapping, functional characterization, and localization

scientific article

Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome

scientific article published on 27 October 2005

Zebrafish tumor assays: the state of transplantation

scientific article published on December 2009

cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes

scientific article published on September 2003

montalcino, A zebrafish model for variegate porphyria

scientific article published on 11 June 2008

Paulina is supported by:

About Paulina

Help