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List of works by Kohjiro Ueki

5-Hydroxytryptamine 2A receptor signaling cascade modulates adiponectin and plasminogen activator inhibitor 1 expression in adipose tissue

scientific article

A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice

scientific article published on 23 April 2015

A qualitative study on the impact of internalized stigma on type 2 diabetes self-management

scientific article published on 8 February 2016

A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response

scientific article

A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese diabetic mice

scientific article

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity

scientific article

A transgenic mutant mouse line accompanied by the complete deletion of interleukin-33 showed insulin and leptin resistances

Acute Inhibition of PI3K-PDK1-Akt Pathway Potentiates Insulin Secretion through Upregulation of Newcomer Granule Fusions in Pancreatic β-Cells ⬇️

scientific article published on October 15, 2012

Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.

scientific article published on 31 March 2010

Adiponectin and adiponectin receptors in obesity-linked insulin resistance.

scientific article published in January 2007

Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake

scientific article

Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway

scientific article published on 28 February 2009

Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance

scientific article

Altered signaling and cell cycle regulation in embryonal stem cells with a disruption of the gene for phosphoinositide 3-kinase regulatory subunit p85alpha

scientific article

Association between Washing Residue on the Feet and Tinea Pedis in Diabetic Patients

scientific article

Association between self-stigma and self-care behaviors in patients with type 2 diabetes: a cross-sectional study

scientific article

Association between type 1 diabetes mellitus and remitting seronegative symmetrical synovitis with pitting edema: a case report

scientific article published on October 29, 2010

Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance

scientific article

Body composition is the main determinant for the difference in type 2 diabetes pathophysiology between Japanese and Caucasians

scientific article published on 15 October 2013

Causes of death in Japanese patients with diabetes based on the results of a survey of 45,708 cases during 2001-2010: Report of the Committee on Causes of Death in Diabetes Mellitus

scientific article

Causes of death in Japanese patients with diabetes based on the results of a survey of 45,708 cases during 2001-2010: report of Committee on Causes of Death in Diabetes Mellitus.

scientific article

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

scientific article

Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis

scientific article published on 29 May 2003

Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization

scientific article

Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms

scientific article published on December 2010

Clinicopathological features of liver injury in patients with type 2 diabetes mellitus and comparative study of histologically proven nonalcoholic fatty liver diseases with or without type 2 diabetes mellitus ⬇️

scientific article published on August 22, 2012

Comparison of Gait Features Between Feet With Callus or Corns and Normal Feet Using Motion Sensors in People With Diabetes and People Without Diabetes

scientific article published on 17 November 2015

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

scientific article

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism.

scientific article published in November 2016

Decreased insulin secretion and accumulation of triglyceride in beta cells overexpressing a dominant-negative form of AMP-activated protein kinase

scientific article published on 19 November 2009

Deregulation of pancreas-specific oxidoreductin ERO1β in the pathogenesis of diabetes mellitus

scientific article published on 27 January 2014

Design of and rationale for the Japan Diabetes Optimal Integrated Treatment study for 3 major risk factors of cardiovascular diseases (J-DOIT3): a multicenter, open-label, randomized, parallel-group trial

scientific article published on 25 January 2016

Design of and rationale for the Japan Diabetes compREhensive database project based on an Advanced electronic Medical record System (J-DREAMS)

Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity

scientific article published on 06 October 2016

Differential roles of insulin receptor substrates in the anti-apoptotic function of insulin-like growth factor-1 and insulin

scientific article published on 24 June 2002

Dipeptidyl peptidase-4 inhibitor anagliptin ameliorates diabetes in mice with haploinsufficiency of glucokinase on a high-fat diet ⬇️

scientific article published on February 8, 2013

Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: an in vivo analysis in MIRKO mice

scholarly article

Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney

scientific article published on 19 June 2017

Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding

scientific article published in July 2008

Education and management of diabetes at The University of Tokyo Hospital ⬇️

scientific article published on June 1, 2011

Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial

scientific article published on 24 October 2017

Effect of renal impairment on the pharmacokinetics, pharmacodynamics, and safety of empagliflozin, a sodium glucose cotransporter 2 inhibitor, in Japanese patients with type 2 diabetes mellitus

scientific article published on 05 September 2014

Factors Associated With Callus in Patients with Diabetes, Focused on Plantar Shear Stress During Gait

scientific article published on 08 May 2016

Factors associated with deep foot fissures in diabetic patients: A cross-sectional observational study ⬇️

scientific article published on February 14, 2012

Factors associated with presence and severity of toenail onychomycosis in patients with diabetes: A cross-sectional study ⬇️

scientific article published on March 2, 2011

Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth

scientific article published on 10 December 2008

Global Mapping of Cell Type–Specific Open Chromatin by FAIRE-seq Reveals the Regulatory Role of the NFI Family in Adipocyte Differentiation ⬇️

scientific article published on October 20, 2011

Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

scientific article published on 9 March 2009

Homeostasis and Disorder of Musculoskeletal System.Roles of the motor system in systemic metabolism and the aging-related disorders

scientific article published in January 2018

Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice

scientific article published in June 2003

Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase

scientific article

Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus

scientific article published on October 2004

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

scientific article published on 19 February 2012

Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity

scientific article

International clinical harmonization of glycated hemoglobin in Japan: From Japan Diabetes Society to National Glycohemoglobin Standardization Program values

scientific article

Japan Diabetes Outcome Intervention Trial 3 (Japan Diabetes Optimal Integrated Treatment Study for 3 major risk factors of cardiovascular diseases: J-DOIT3)

scientific article published in May 2010

Lipoatrophic diabetes in Irs1(-/-)/Irs3(-/-) double knockout mice

scientific article published on December 2002

Long-term safety and efficacy of exenatide twice daily in Japanese patients with suboptimally controlled type 2 diabetes

scientific article

Loss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity

scientific article published on 28 October 2011

Lung abscess without sepsis in a patient with diabetes with refractory episodes of spontaneous hypoglycemia: a case report and review of the literature

scientific article published on 13 February 2014

Molecular Balance between the Regulatory and Catalytic Subunits of Phosphoinositide 3-Kinase Regulates Cell Signaling and Survival ⬇️

scientific article published on February 1, 2002

Molecular mechanism of moderate insulin resistance in adiponectin-knockout mice

scientific article

Morphological pattern classification system for plantar thermography of patients with diabetes

scientific article published on September 2013

New glycemic targets for patients with diabetes from the Japan Diabetes Society

scientific article published on 09 December 2016

New glycemic targets for patients with diabetes from the Japan Diabetes Society.

scientific article

Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance

scientific article

Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases expression of very low density lipoprotein receptor gene in adipocytes

scientific article published on 25 August 2009

Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity

scientific article

Phosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in mice

scientific article

Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN.

scholarly article

Pioglitazone Ameliorates Smooth Muscle Cell Proliferation in Cuff-Induced Neointimal Formation by Both Adiponectin-Dependent and -Independent Pathways

scientific article published on 05 October 2016

Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways

scientific article published on 23 January 2006

Positive and Negative Roles of p85α and p85β Regulatory Subunits of Phosphoinositide 3-Kinase in Insulin Signaling ⬇️

scientific article published on September 22, 2003

Positive and negative roles of p85α and p85β regulatory subunits of phosphoinositide 3-kinase in insulin signaling

scientific article published on March 2017

Psychological and behavioural patterns of stigma among patients with type 2 diabetes: a cross-sectional study

scientific article published on 29 March 2017

Recommended configuration for personal health records by standardized data item sets for diabetes mellitus and associated chronic diseases: A report from Collaborative Initiative by six Japanese Associations

article

Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

scientific article

Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in βIRKO mice ⬇️

scientific article published on September 30, 2003

Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic beta-cells

scientific article

Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia

scientific journal article

Relationship between elevated plantar pressure of toes and forefoot and gait features in diabetic patients

scientific article

Report of the Committee on the classification and diagnostic criteria of diabetes mellitus

article by Yutaka Seino et al published 28 October 2010 in Diabetology international

Report of the JDS/JCA Joint Committee on Diabetes and Cancer

Report of the Japan Diabetes Society/Japanese Cancer Association Joint Committee on Diabetes and Cancer

scientific article published in July 2013

Report of the Japan diabetes society/Japanese cancer association joint committee on diabetes and cancer, Second report

scientific article

Report of the committee on the classification and diagnostic criteria of diabetes mellitus

scientific article

Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways

scientific article

Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome

scientific article

Site and mechanism of leptin action in a rodent form of congenital lipodystrophy

scientific article published on February 2004

SnapShot: Insulin Signaling Pathways ⬇️

scientific article published on February 3, 2012

Stretch-induced Retinal Vascular Endothelial Growth Factor Expression Is Mediated by Phosphatidylinositol 3-Kinase and Protein Kinase C (PKC)-ζ but Not by Stretch-induced ERK1/2, Akt, Ras, or Classical/Novel PKC Pathways ⬇️

scientific article published on January 11, 2002

Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

scientific journal article

TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass

scientific article

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

The Association between Tinea Pedis and Feet-Washing Behavior in Patients with Diabetes: A Cross-sectional Study

scientific article published in November 2017

The mechanisms whereby insulin/IGF-1 signaling regulates aging and longevity

scientific article published in July 2009

The p85alpha regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance

scientific article published on 5 February 2007

The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation

scientific journal article

Tofogliflozin Improves Insulin Resistance in Skeletal Muscle and Accelerates Lipolysis in Adipose Tissue in Male Mice

scientific article published on 29 December 2015

Tumstatin, an endothelial cell-specific inhibitor of protein synthesis

scientific article

Vascular endothelial growth factor activates PI3K/Akt/forkhead signaling in endothelial cells

scientific article

p50alpha/p55alpha phosphoinositide 3-kinase knockout mice exhibit enhanced insulin sensitivity

scientific article

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