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List of works by Scott E Guimond

2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline.

scientific article published on 15 June 2015

A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer's Disease.

scientific article published on 16 May 2019

A semi-synthetic glycosaminoglycan analogue inhibits and reverses Plasmodium falciparum cytoadherence.

scientific article published on 18 October 2017

Dendrimer Heparan Sulfate Glycomimetics: Potent Heparanase Inhibitors for Anticancer Therapy

scientific article published on 29 November 2018

Differential sulfation remodelling of heparan sulfate by extracellular 6-O-sulfatases regulates fibroblast growth factor-induced boundary formation by glial cells: implications for glial cell transplantation.

scientific article

Disaccharide compositional analysis of heparan sulfate and heparin polysaccharides using UV or high-sensitivity fluorescence (BODIPY) detection.

scientific article published on 2 December 2010

Disruption of rosetting in Plasmodium falciparum malaria with chemically modified heparin and low molecular weight derivatives possessing reduced anticoagulant and other serine protease inhibition activities.

scientific article published on 9 February 2008

Distinct patterns of heparan sulphate in pancreatic islets suggest novel roles in paracrine islet regulation

scientific article published on 16 September 2014

Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity

scientific article

Dynamic changes in heparan sulfate during muscle differentiation and ageing regulate myoblast cell fate and FGF2 signalling

scientific article published on 02 August 2016

Engineered bio-active polysaccharides from heparin.

scientific article published in August 2006

Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor.

scientific article

Glycomics profiling of heparan sulfate structure and activity.

scientific article

Glycosaminoglycan origin and structure revealed by multivariate analysis of NMR and CD spectra

article

Glycosaminoglycans induce conformational change in the SARS-CoV-2 Spike S1 Receptor Binding Domain

scientific article published on 30 April 2020

Heparan Sulfate Proteoglycan Synthesis Is Dysregulated in Human Osteoarthritic Cartilage

scientific article published on 14 December 2018

Heparan sulfate phage display antibodies recognise epitopes defined by a combination of sugar sequence and cation binding.

scientific article published on June 2015

Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin

scientific article published on 29 April 2020

Novel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1

scientific article

Proteoglycans make the grade-ient.

scientific article published in October 2004

Rapid purification and high sensitivity analysis of heparan sulfate from cells and tissues: toward glycomics profiling.

scientific article published on 13 July 2009

SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins

scientific article published on 30 April 2020

Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions

scientific article

Sulfatase-mediated manipulation of the astrocyte-Schwann cell interface.

scientific article

The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding

scientific article (preprint)

The activities of heparan sulfate and its analogue heparin are dictated by biosynthesis, sequence, and conformation.

scientific article published on January 2008

The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids

article

Tools for the Quality Control of Pharmaceutical Heparin

scientific article published on 25 September 2019

Versatile Separation and Analysis of Heparan Sulfate Oligosaccharides Using Graphitized Carbon Liquid Chromatography and Electrospray Mass Spectrometry

scientific article

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