List of works by Bridget Wilson

3-Dimensional Tracking of Non-blinking 'Giant' Quantum Dots in Live Cells

scientific article

A comparison of inflammatory mediators released by basophils of asthmatic and control subjects in response to high-affinity IgE receptor aggregation

scientific article published on 02 October 2007

A structural equation model of posttraumatic growth after prostate cancer.

scientific article

Actin restricts FcepsilonRI diffusion and facilitates antigen-induced receptor immobilization

scientific article

Activated N-formyl peptide receptor and high-affinity IgE receptor occupy common domains for signaling and internalization

scientific article

Adopting a survivor identity after cancer in a peer support context

scientific article

Allergen Valency, Dose, and FcεRI Occupancy Set Thresholds for Secretory Responses to Pen a 1 and Motivate Design of Hypoallergens.

scientific article published on 30 December 2016

Calcium-dependent clustering of inositol 1,4,5-trisphosphate receptors

scientific article published on June 1998

Caught in the act: quantifying protein behaviour in living cells

scientific article published on 02 October 2009

Characterization of the anti-CD22 targeted therapy, moxetumomab pasudotox, for B-cell precursor acute lymphoblastic leukemia

scientific article published on 27 April 2017

Characterizing the topography of membrane receptors and signaling molecules from spatial patterns obtained using nanometer-scale electron-dense probes and electron microscopy

scientific article

Combinatorial diversity of Syk recruitment driven by its multivalent engagement with FcεRIγ

scientific article published on 19 June 2019

Confocal imaging studies cast doubt on nuclear localization of JAK2V617F.

scientific article published on September 2011

Cooperation between the Fc epsilonR1 and formyl peptide receptor signaling pathways in RBL(FPR) cells: the contribution of receptor-specific Ca2+ mobilization responses

scientific article published on 01 June 1997

Coupled stochastic spatial and non-spatial simulations of ErbB1 signaling pathways demonstrate the importance of spatial organization in signal transduction

scientific article

Depletion of guanine nucleotides with mycophenolic acid suppresses IgE receptor-mediated degranulation in rat basophilic leukemia cells

scientific article published on 01 July 1989

Differential expression of Ikaros isoforms in monozygotic twins with MLL-rearranged precursor-B acute lymphoblastic leukemia.

scientific article published in December 2008

Differential mast cell outcomes are sensitive to FcεRI-Syk binding kinetics

scientific article published on 30 August 2017

Distinct functions of the Fc epsilon R1 gamma and beta subunits in the control of Fc epsilon R1-mediated tyrosine kinase activation and signaling responses in RBL-2H3 mast cells.

scientific article published on February 1995

Distribution and dynamics of rat basophilic leukemia immunoglobulin E receptors (FcepsilonRI) on planar ligand-presenting surfaces

scientific article

Dynamic pre-BCR homodimers fine-tune autonomous survival signals in B cell precursor acute lymphoblastic leukemia.

scientific article

Dynamic transition states of ErbB1 phosphorylation predicted by spatial stochastic modeling

scientific article published on September 2013

Dysregulated FcepsilonRI signaling and altered Fyn and SHIP activities in Lyn-deficient mast cells.

scientific article published on July 2004

Editorial: Structure, Isotypes, Targets, and Post-translational Modifications of Immunoglobulins and Their Role in Infection, Inflammation and Autoimmunity

scientific article published on 07 August 2020

Effect of Spatial Inhomogeneities on the Membrane Surface on Receptor Dimerization and Signal Initiation

scientific article published on 12 August 2016

Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer

scientific article

ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding

scientific article published on 23 October 2011

Exploring membrane domains using native membrane sheets and transmission electron microscopy

scientific article published on January 2007

FcepsilonRI signaling observed from the inside of the mast cell membrane

scientific article

FcεRI Signal Propagation is Regulated through Transient Binding of Syk

Formation of a mast cell synapse: Fc epsilon RI membrane dynamics upon binding mobile or immobilized ligands on surfaces

scientific article

GSI-I (Z-LLNle-CHO) inhibits γ-secretase and the proteosome to trigger cell death in precursor-B acute lymphoblastic leukemia.

scientific article

Gene editing rescue of a novel MPL mutant associated with congenital amegakaryocytic thrombocytopenia

scientific article published on 22 September 2017

Going beyond 2D: Following membrane diffusion and topography in the IgE-Fc[Epsilon]RI system using 3-dimensional tracking microscopy.

scientific article

High incidence of ErbB3, ErbB4, and MET expression in ovarian cancer

scientific article

High level expression of transfected G protein alpha i3 subunit is required for plasma membrane targeting and adenylyl cyclase inhibition in NIH 3T3 fibroblasts.

scientific article published on November 1992

High resolution mapping of mast cell membranes reveals primary and secondary domains of Fc(epsilon)RI and LAT.

scientific article

Histamine release from the basophils of control and asthmatic subjects and a comparison of gene expression between "releaser" and "nonreleaser" basophils

scientific article

IKK inhibitor bay 11-7082 induces necroptotic cell death in precursor-B acute lymphoblastic leukaemic blasts.

scientific article published in December 2009

Identification of the Fc epsilonRI-activated tyrosine kinases Lyn, Syk, and Zap-70 in human basophils

scientific article published on 01 August 1998

IgE alone stimulates mast cell adhesion to fibronectin via pathways similar to those used by IgE + antigen but distinct from those used by Steel factor ⬇️

scientific article published on April 17, 2003

Immunologically mediated signaling in basophils and mast cells: finding therapeutic targets for allergic diseases in the human FcvarepsilonR1 signaling pathway.

scientific article

Impaired secretion and increased insolubilization of IgE-receptor complexes in mycophenolic acid-treated (guanine nucleotide-depleted) RBL-2H3 mast cells ⬇️

scientific article published on December 1, 1991

Increased expression of genes linked to FcepsilonRI Signaling and to cytokine and chemokine production in Lyn-deficient mast cells

scientific article

Inhibition of mast cell Fc epsilon R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol.

scientific article published on November 1994

Inside-Out Signaling of Oncogenic EGFR Mutants Promotes Ligand-Independent Dimerization

article published in 2015

Insights into cell membrane microdomain organization from live cell single particle tracking of the IgE high affinity receptor FcϵRI of mast cells

scientific article published on 26 June 2012

Leukemia-derived exosomes and cytokines pave the way for entry into the brain

scientific article published on 31 January 2019

Lyn dissociation from phosphorylated Fc epsilon RI subunits: a new regulatory step in the Fc epsilon RI signaling cascade revealed by studies of Fc epsilon RI dimer signaling activity

scientific article published on 01 January 1999

MEK and ERK activation in ras-disabled RBL-2H3 mast cells and novel roles for geranylgeranylated and farnesylated proteins in Fc epsilonRI-mediated signaling

scientific article published on 01 December 1998

Macrophage and NK-mediated killing of precursor-B acute lymphoblastic leukemia cells targeted with a-fucosylated anti-CD19 humanized antibodies

scientific article

Mapping ErbB receptors on breast cancer cell membranes during signal transduction

scientific article published on 24 July 2007

Markers for detergent-resistant lipid rafts occupy distinct and dynamic domains in native membranes.

scientific article

Markov random field modeling of the spatial distribution of proteins on cell membranes

scientific article published on 29 September 2007

Mast cell synapses and exosomes: membrane contacts for information exchange

scientific article published on 15 March 2012

Mast cells in atopic dermatitis

scientific article

Mathematical simulation of membrane protein clustering for efficient signal transduction

scientific article published on 06 June 2012

Membrane receptor mapping: the membrane topography of Fc(epsilon)RI signaling.

scientific article

Microtubule-dependent transport of secretory vesicles in RBL-2H3 cells

scientific article published in May 2003

Modeling biomolecular site dynamics in immunoreceptor signaling systems.

scientific article

Molecular Mechanism of Interfacial Adsorption of Disordered Cytoplasmic Tail of Immune Receptors to Membrane

Monoclonal IgG in MGUS and multiple myeloma targets infectious pathogens

scientific article published on 5 October 2017

Mpl traffics to the cell surface through conventional and unconventional routes

scientific article

Multiple defects in Fc epsilon RI signaling in Syk-deficient nonreleaser basophils and IL-3-induced recovery of Syk expression and secretion.

scientific article published in November 2000

Multiple roles for PI 3-kinase in the regulation of PLCgamma activity and Ca2+ mobilization in antigen-stimulated mast cells.

scientific article

Multisite EGFR phosphorylation is regulated by adaptor protein abundances and dimer lifetimes

scientific article published on 08 January 2020

Negative regulation of FcϵRI signaling by FcγRII costimulation in human blood basophils

scientific article published on 01 August 2000

Newfound compassion after prostate cancer: a psychometric evaluation of additional items in the Posttraumatic Growth Inventory.

scientific article

Note: Time-gated 3D single quantum dot tracking with simultaneous spinning disk imaging

scientific article published in December 2015

Observing FcepsilonRI signaling from the inside of the mast cell membrane

scientific article

Optimal aggregation of FcεRI with a structurally defined trivalent ligand overrides negative regulation driven by phosphatases.

scientific article

Orchestration of ErbB3 signaling through heterointeractions and homointeractions

scientific article

Ovarian tumor attachment, invasion, and vascularization reflect unique microenvironments in the peritoneum: insights from xenograft and mathematical models.

scientific article

Pivotal advance: IgE accelerates in vitro development of mast cells and modifies their phenotype.

scientific article published on 13 May 2008

Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton

scholarly article

Proteasome-dependent regulation of Syk tyrosine kinase levels in human basophils

scientific article

Pyrosequencing for classification of human FcγRIIIA allotypes: a comparison with PCR-based techniques.

scientific article published in December 2014

Reduced FcepsilonRI-mediated release of asthma-promoting cytokines and chemokines from human basophils during omalizumab therapy

scientific article

Regulation of IgE receptor-mediated secretion from RBL-2H3 mast cells by GTP binding-proteins and calcium ⬇️

scientific article published on February 14, 1991

Regulation of the very late antigen-4-mediated adhesive activity of normal and nonreleaser basophils: roles for Src, Syk, and phosphatidylinositol 3-kinase.

scientific article

Relationship of ligand-receptor dynamics to actin polymerization in RBL-2H3 cells transfected with the human formyl peptide receptor

scientific article published on 01 October 1997

Revealing the topography of cellular membrane domains by combined atomic force microscopy/fluorescence imaging

scientific article

Roles for the High Affinity IgE Receptor, FcεRI, of Human Basophils in the Pathogenesis and Therapy of Allergic Asthma: Disease Promotion, Protection or Both?

scientific article published on January 2010

STAT1 activation causes translocation of Bax to the endoplasmic reticulum during the resolution of airway mucous cell hyperplasia by IFN-gamma.

scientific article published in June 2007

Selection and characterization of FcεRI phospho-ITAM specific antibodies

scientific article published on 16 July 2019

Sensitivity analysis predicts that the ERK–pMEK interaction regulates ERK nuclear translocation ⬇️

scientific article published on September 1, 2009

Single Molecule Imaging Reveals that Activating Kinase Domain Mutations Reduce EGFR Mobility and Enhance Dimerization

article

Single-cell measurements of IgE-mediated FcεRI signaling using an integrated microfluidic platform

scientific article published on 27 March 2013

Small, mobile FcepsilonRI receptor aggregates are signaling competent

scientific article

Spatial Modeling of Drug Delivery Routes for Treatment of Disseminated Ovarian Cancer

scientific article published on 30 December 2015

Spatio-temporal modeling of signaling protein recruitment to EGFR.

scientific article

Spatio-temporal signaling in mast cells

scientific article published on January 2011

Stochastic modeling of calcium in 3D geometry.

scientific article

Stochastic simulations of ErbB homo and heterodimerisation: potential impacts of receptor conformational state and spatial segregation.

scientific article published on September 2008

Syk deficiency in nonreleaser basophils

scientific article published on 01 August 1999

Synthesizing biofunctionalized nanoparticles to image cell signaling pathways

scientific article published on December 2006

The Src kinase Lyn is a negative regulator of mast cell proliferation

scientific journal article

The architectural relationship of components controlling mast cell endocytosis

scientific article

Three dimensional time-gated tracking of non-blinking quantum dots in live cells

scientific article published on March 2015

Time-resolved three-dimensional molecular tracking in live cells

scientific article

Timescale Separation of Positive and Negative Signaling Creates History-Dependent Responses to IgE Receptor Stimulation

scientific article published on 14 November 2017

Using hierarchical clustering and dendrograms to quantify the clustering of membrane proteins

scientific article published on 13 July 2011

Visualizing clathrin-mediated IgE receptor internalization by electron and atomic force microscopy

scientific article published on 01 January 2008

Water-soluble germanium(0) nanocrystals: cell recognition and near-infrared photothermal conversion properties

scientific article

Wortmannin blocks lipid and protein kinase activities associated with PI 3-kinase and inhibits a subset of responses induced by Fc epsilon R1 cross-linking

scientific article

Wortmannin-sensitive phosphorylation, translocation, and activation of PLCgamma1, but not PLCgamma2, in antigen-stimulated RBL-2H3 mast cells

scientific article published on February 1998

erbB3 is an active tyrosine kinase capable of homo- and heterointeractions

scientific article published on 30 December 2013

p110beta and p110delta phosphatidylinositol 3-kinases up-regulate Fc(epsilon)RI-activated Ca2+ influx by enhancing inositol 1,4,5-trisphosphate production.

scientific article

Paulina is supported by:

About Paulina

Help