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List of works by Tomas Kirchhausen

A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating

scientific article

ADVANCED IMAGING. Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics

scientific article

ARFGAP1 promotes AP-2-dependent endocytosis.

scientific article

Actin dynamics counteract membrane tension during clathrin-mediated endocytosis ⬇️

scientific article published on August 14, 2011

An ACAP1-containing clathrin coat complex for endocytic recycling

scientific article

Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling

scientific article

Chemical genetic screening identifies sulfonamides that raise organellar pH and interfere with membrane traffic

scientific article published on July 2004

Cholera toxin toxicity does not require functional Arf6- and dynamin-dependent endocytic pathways.

scientific article

Conservation in vesicle coats

scientific article published in Nature

Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells

scientific article published on 01 January 2020

Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide

scientific article published on 21 April 2004

Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly

scientific article published on 14 October 2006

Crystal structure of the clathrin adaptor protein 1 core

scholarly article

Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes

scientific article published on 21 May 2015

Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes.

scientific article

Data publication with the structural biology data grid supports live analysis

scientific article

Differential evanescence nanometry: live-cell fluorescence measurements with 10-nm axial resolution on the plasma membrane

scientific article

Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI.

scientific article

Distinct dynamics of endocytic clathrin-coated pits and coated plaques

scientific article (publication date: September 2009)

Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR-Cas9 genome editing

scientific article published on 09 October 2017

Effects of dynamin inactivation on pathways of anthrax toxin uptake

scientific article published in July 2004

Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation.

scientific article published on 13 June 2013

Endocytosis by random initiation and stabilization of clathrin-coated pits

scientific article published on September 2004

Endocytosis is not required for the selective lipid uptake mediated by murine SR-BI.

scientific article published on 9 March 2005

Endosomal recycling controls plasma membrane area during mitosis

scholarly article

Erratum: Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin–AP-1-coated carrier biogenesis at the TGN

scholarly article published in Nature Cell Biology

Exo1: a new chemical inhibitor of the exocytic pathway

scientific article

F-BAR domain only protein 1 (FCHO1) deficiency is a novel cause of combined immune deficiency in human subjects

scientific article published on 26 February 2019

Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly

scientific article

HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation

scientific article published on 01 September 2020

HIV Nef-mediated Major Histocompatibility Complex Class I Down-Modulation Is Independent of Arf6 Activity ⬇️

scientific article published on November 14, 2003

Host cell nucleolin is required to maintain the architecture of human cytomegalovirus replication compartments.

scientific article published on 7 February 2012

Human cytomegalovirus UL44 concentrates at the periphery of replication compartments, the site of viral DNA synthesis.

scientific article

Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity

scientific article published on 08 December 2007

In vivo analysis of formation and endocytosis of the Wnt/β-Catenin signaling complex in zebrafish embryos.

scientific article published on 14 December 2014

In vivo analysis of formation and endocytosis of the Wnt/β-catenin signaling complex in zebrafish embryos

scientific article

Inhibition of PIKfyve kinase prevents infection by EBOV and SARS-CoV-2

scientific article published on 22 April 2020

Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2

scientific article published on 06 August 2020

Invasive and adherent bacterial pathogens co-Opt host clathrin for infection

scientific article

L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1.

scientific article

Large scale synthesis of the Cdc42 inhibitor secramine A and its inhibition of cell spreading

scientific article published on 01 November 2006

Live-cell visualization of pre-mRNA splicing with single-molecule sensitivity

scientific article published on 12 September 2013

Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin.

scientific article

Macropinocytosis: regulated coordination of endocytic and exocytic membrane traffic events

scientific article

Making COPII coats

scientific article published on June 2007

Mammalian cells change volume during mitosis

scientific article

Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy

scientific article

Molecular model for a complete clathrin lattice from electron cryomicroscopy

scientific article

NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry.

scientific article published in November 2017

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms

scientific article published in April 2018

Oligomerization of the vesicular stomatitis virus phosphoprotein is dispensable for mRNA synthesis but facilitates RNA replication

scientific article published on 22 April 2020

PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal

scientific article published on 9 May 2007

Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis

scientific journal article

Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells

scientific article

Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

scientific article published in September 2005

Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi

scientific article

Possible role of deep tubular invaginations of the plasma membrane in MHC-I trafficking

scientific article

Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN.

scientific article

Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding

scientific article published on 11 October 2017

Recruitment of Cellular Clathrin to Viral Factories and Disruption of Clathrin‐Dependent Trafficking ⬇️

scientific article published on July 7, 2011

Redistribution of caveolae during mitosis

scientific article

Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds.

scientific article

Retrograde transport of cholera toxin from the plasma membrane to the endoplasmic reticulum requires the trans-Golgi network but not the Golgi apparatus in Exo2-treated cells

scientific article

Role of lipids and actin in the formation of clathrin-coated pits

scientific article

Roles of AP-2 in clathrin-mediated endocytosis

scientific article

Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion

scientific article published on 24 October 2016

Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro.

scientific article published on 20 November 2005

Seipin is required for converting nascent to mature lipid droplets

scientific article

Shiga Toxin Increases Formation of Clathrin-Coated Pits through Syk Kinase ⬇️

scientific article published on July 27, 2010

Similar uptake but different trafficking and escape routes of reovirus virions and infectious subvirion particles imaged in polarized Madin-Darby canine kidney cells.

scientific article

Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating

scientific article

Single-molecule live-cell imaging of clathrin-based endocytosis.

scientific article

Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells

scientific article

Structural Analysis of the Interaction between Dishevelled2 and Clathrin AP-2 Adaptor, A Critical Step in Noncanonical Wnt Signaling ⬇️

scientific article published on October 13, 2010

Structural correlates of rotavirus cell entry

scientific article

Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy

scientific article

Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating

scientific article published on 24 October 2004

Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly

scientific article

Structure of the PTEN-like Region of Auxilin, a Detector of Clathrin-Coated Vesicle Budding

scientific article

Superinfection exclusion is absent during acute Junin virus infection of Vero and A549 cells

scientific article

Synergistic Block of SARS-CoV-2 Infection by Combined Drug Inhibition of the Host Entry Factors PIKfyve Kinase and TMPRSS2 Protease

scientific article published on 18 August 2021

Synthesis of a 10,000-membered library of molecules resembling carpanone and discovery of vesicular traffic inhibitors

scientific article

T cells induce extended class II MHC compartments in dendritic cells in a Toll-like receptor-dependent manner

scientific article published on 01 October 2003

Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation

scientific article

The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells

scientific article published on 18 March 2006

The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles.

scientific article published in July 2018

The Length of Vesicular Stomatitis Virus Particles Dictates a Need for Actin Assembly during Clathrin-Dependent Endocytosis ⬇️

scientific article published on September 30, 2010

The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation

scientific article

The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry.

scientific article published on December 2003

The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites

scientific article

The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing

scientific article

The timing of pre-mRNA splicing visualized in real-time

scientific article

The transcription factor NFAT3 mediates neuronal survival

scientific article

Uptake of rabies virus into epithelial cells by clathrin-mediated endocytosis depends upon actin

scientific article

Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown

scientific article

Visualizing the high curvature regions of post-mitotic nascent nuclear envelope membrane ⬇️

scientific article published on January 1, 2012

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