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List of works by Wei-Yi Chen

A PRC2-Kdm5b axis sustains tumorigenicity of acute myeloid leukemia

scientific article published on 25 February 2022

A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis ⬇️

scientific article published on June 30, 2013

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting

scientific article

Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1.

scientific article published on 6 September 2018

Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation

scientific article published on 01 January 2019

BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis

scientific article published on 02 November 2020

DNMT3b protects centromere integrity by restricting R-loop-mediated DNA damage

scientific article published on 11 June 2022

Distinct functions of steroidogenic factor-1 (NR5A1) in the nucleus and the centrosome ⬇️

scientific article published on 05 December 2012

E2A-PBX1 functions as a coactivator for RUNX1 in acute lymphoblastic leukemia

scientific article published on 10 April 2020

Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development

scientific article published on 17 June 2016

Functions of paralogous RNA polymerase III subunits POLR3G and POLR3GL in mouse development

scientific article published on 23 June 2020

Histone deacetylase inhibitors reduce steroidogenesis through SCF-mediated ubiquitination and degradation of steroidogenic factor 1 (NR5A1).

scientific article

Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia

scientific article published on 29 October 2012

Mediator subunit MED1 is required for E2A-PBX1-mediated oncogenic transcription and leukemic cell growth

scientific article published on 9 February 2021

Protein phosphatase inhibitor cantharidin inhibits steroidogenesis and steroidogenic acute regulatory protein expression in cultured rat preovulatory follicles

scientific article published in November 2001

Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains ⬇️

scientific article published on February 18, 2011

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53

scientific article

SF-1 (nuclear receptor 5A1) activity is activated by cyclic AMP via p300-mediated recruitment to active foci, acetylation, and increased DNA binding.

scientific article

SUMO modification of repression domains modulates function of nuclear receptor 5A1 (steroidogenic factor-1).

scientific article published on 10 June 2004

Steroidogenic Factor 1 (NR5A1) resides in centrosomes and maintains genomic stability by controlling centrosome homeostasis.

scientific article published on 13 May 2011

Steroidogenic factor 1 (NR5A1) maintains centrosome homeostasis in steroidogenic cells by restricting centrosomal DNA-dependent protein kinase activation

scientific article published on 19 November 2012

Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus

scientific article

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