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List of works by Jesus M Banales

Activation of the developmental pathway neurogenin-3/microRNA-7a regulates cholangiocyte proliferation in response to injury.

scientific article published on 25 August 2014

Adaptive downregulation of Cl-/HCO3- exchange activity in rat hepatocytes under experimental obstructive cholestasis

scientific article published on 21 February 2019

Ageing-related expression of Twinfilin-1 regulates cholangiocyte biological response to injury

scientific article published on 18 December 2018

Anion exchanger 2 is critical for CD8(+) T cells to maintain pHi homeostasis and modulate immune responses

scientific article published on 11 March 2014

Bicarbonate secretion of mouse cholangiocytes involves Na(+)-HCO(3)(-) cotransport in addition to Na(+)-independent Cl(-)/HCO(3)(-) exchange.

scientific article published in March 2010

Bicarbonate-rich choleresis induced by secretin in normal rat is taurocholate-dependent and involves AE2 anion exchanger

scientific journal article

Bile Acids in Polycystic Liver Diseases: Triggers of Disease Progression and Potential Solution for Treatment.

scientific article published on March 2017

Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia.

scientific article

Biliary secretion of S-nitrosoglutathione is involved in the hypercholeresis induced by ursodeoxycholic acid in the normal rat.

scientific article

CXCR7 contributes to the aggressive phenotype of cholangiocarcinoma cells

scientific article published on 03 May 2019

Cancer-associated circulating large extracellular vesicles in cholangiocarcinoma and hepatocellular carcinoma.

scientific article published on 3 March 2017

Causes of hOCT1-Dependent Cholangiocarcinoma Resistance to Sorafenib and Sensitization by Tumor-Selective Gene Therapy

article

Centrosomal abnormalities characterize human and rodent cystic cholangiocytes and are associated with Cdc25A overexpression.

scientific article

Cholangiocarcinoma 2020: the next horizon in mechanisms and management

scientific article published on 30 June 2020

Cholangiocarcinoma stem-like subset shapes tumor-initiating niche by educating associated macrophages

scientific article published in September 2016

Cholangiocarcinoma: State-of-the-art knowledge and challenges

scientific article published on 01 May 2019

Cholangiocyte anion exchange and biliary bicarbonate excretion

scientific article published on June 2006

Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion.

scholarly article

Cholangiocyte pathobiology.

scientific article

Cholangiocyte-to-Hepatocyte Differentiation: a Context Dependent Process and an Opportunity for Regenerative Medicine

scientific article published on 31 December 2018

Cholangiocytes in health and disease: From basic science to novel treatments

scientific article published on 18 January 2018

Clinical management of polycystic liver disease

scientific article published on 23 November 2017

Cocarcinogenic effects of intrahepatic bile acid accumulation in cholangiocarcinoma development.

scientific article published on 19 November 2013

Current and novel therapeutic opportunities for systemic therapy in biliary cancer

scientific article published on 22 July 2020

Development and Validation of Hepamet Fibrosis Scoring System A Simple, Noninvasive Test to Identify Patients With Nonalcoholic Fatty Liver Disease With Advanced Fibrosis

scientific article published on 11 June 2019

Diagnostic and prognostic biomarkers in cholangiocarcinoma

scientific article published on 01 May 2019

Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression

scientific article published on 12 September 2017

Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma

scientific article published on 04 January 2019

Effect of pravastatin on the survival of patients with advanced gastric cancer.

scientific article published on 28 December 2015

Effects of endotoxin on type 3 inositol 1,4,5-trisphosphate receptor in human cholangiocytes

scientific article published on 31 December 2018

Elevated interleukin-8 in bile of patients with primary sclerosing cholangitis.

scientific article published on 11 February 2016

Enhanced antitumour drug delivery to cholangiocarcinoma through the apical sodium-dependent bile acid transporter (ASBT).

scientific article published on 13 August 2015

Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

scientific article published on 11 February 2019

Evaluation of the Effect of 1,3-Bis(4-Phenyl)-1H-1,2,3-Triazolyl-2-Propanolol on Gene Expression Levels of JAK2-STAT3, NF-κB, and SOCS3 in Cells Cultured from Biopsies of Mammary Lesions.

scientific article

Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA).

scientific article published on 20 April 2016

Expression of SLC22A1 variants may affect the response of hepatocellular carcinoma and cholangiocarcinoma to sorafenib.

scientific article published on 30 July 2013

Extracellular Vesicles in Hepatobiliary Malignancies

scientific article published on 12 October 2018

Functional crosstalk between the adenosine transporter CNT3 and purinergic receptors in the biliary epithelia.

scientific article published on 14 July 2014

Genetics of polycystic liver diseases

scientific article published on 01 March 2019

Genetics: Novel causative genes for polycystic liver disease

scientific article published on 31 May 2017

Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease

scientific journal article

High fluorescence cell count in ascitic body fluids for carcinomatosis screening

scientific article published on 01 October 2018

Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1

scientific article

Inhibition of Cdc25A Suppresses Hepato-renal Cystogenesis in Rodent Models of Polycystic Kidney and Liver Disease ⬇️

scientific article published on December 7, 2011

Inhibition of metalloprotease hyperactivity in cystic cholangiocytes halts the development of polycystic liver diseases

scientific article

Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation.

scientific article published on 10 May 2016

Linezolid-induced lactic acidosis in two liver transplant patients with the mitochondrial DNA A2706G polymorphism.

scientific article

Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair

scientific article published on 16 October 2013

Measurement of liver iron concentration by MRI is reproducible

scientific article published on 22 March 2015

Mechanisms of Resistance to Chemotherapy in Gastric Cancer.

scientific article published on 03 August 2015

Metabolic rearrangements in primary liver cancers: cause and consequences

scientific article published on 30 October 2019

Methods for extracellular vesicles isolation in a hospital setting.

scientific article published on 13 February 2015

MiR-433 and miR-22 dysregulations induce HDAC6 overexpression and ciliary loss in cholangiocarcinoma.

scientific article published on 6 February 2018

MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

scientific article published on 20 September 2018

MiRNA-506 promotes primary biliary cholangitis-like features in cholangiocytes and immune activation.

scientific article published on 18 September 2017

MicroRNAs and cholestatic liver diseases.

scientific article published on May 2014

MicroRNAs and extracellular vesicles in cholangiopathies.

scientific article

MicroRNAs in biliary diseases.

scientific article

MicroRNAs in cholangiopathies: Potential diagnostic and therapeutic tools.

scientific article

Molecular Mechanisms of Cholangiocarcinogenesis: New Potential Targets for Therapy.

scientific article published on 25 August 2015

More insight into the diversity of cholangiocyte ciliopathies

scientific article published on 31 August 2016

Multi-Omics Integration Highlights the Role of Ubiquitination in CCl<sub>4</sub>-Induced Liver Fibrosis

scientific article published on 27 November 2020

Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease

scientific article

Neutrophils interact with cholangiocytes to cause cholestatic changes in alcoholic hepatitis

scientific article published on 19 November 2020

New Advances in Polycystic Liver Diseases.

scientific article published on 15 February 2017

New Advances in the Molecular Mechanisms Driving Biliary Fibrosis and Emerging Molecular Targets.

scientific article published on 27 April 2015

New evidence supporting the biliary bicarbonate umbrella theory

article

Nlrp3 Activation Induces Il-18 Synthesis and Affects the Epithelial Barrier Function in Reactive Cholangiocytes.

scientific article published on 29 November 2016

Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage

scientific article

Novel equation to determine the hepatic triglyceride concentration in humans by MRI: diagnosis and monitoring of NAFLD in obese patients before and after bariatric surgery

scientific article

Novel lncRNA T-UCR as a potential downstream driver of the Wnt/β-catenin pathway in hepatobiliary carcinogenesis

scientific article published on 16 December 2016

Nuclear Translocation of RELB is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice

scientific article published on 13 November 2018

O-GlcNAcylation: Undesired tripmate but an opportunity for treatment in NAFLD-HCC

scientific article published on 08 May 2017

Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice

scientific article

PNPLA3 p.I148M variant is associated with greater reduction of liver fat content after bariatric surgery

scientific article published on July 2016

Pasireotide is more effective than octreotide in reducing hepatorenal cystogenesis in rodents with polycystic kidney and liver diseases.

scientific article published on 6 March 2013

Pathobiology of inherited biliary diseases: a roadmap to understand acquired liver diseases

scientific article published on 01 August 2019

Polycystic liver diseases: advanced insights into the molecular mechanisms

scientific article

Post-translational regulation of the type III inositol 1,4,5-trisphosphate receptor by miRNA-506.

scientific article

Pravastatin inhibits cell proliferation and increased MAT1A expression in hepatocarcinoma cells and in vivo models

scientific article published on 21 February 2012

Prevalence of Malnutrition and Nutritional Characteristics of Patients With Inflammatory Bowel Disease.

scientific article published on 24 July 2017

Primary biliary cholangitis: A tale of epigenetically-induced secretory failure?

scientific article published on 05 September 2018

Proteostasis disturbances and endoplasmic reticulum stress contribute to polycystic liver disease: New therapeutic targets

scientific article published on 06 May 2020

Pyroptosis: an inflammatory link between NAFLD and NASH with potential therapeutic implications.

scientific article published on 2 February 2018

RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury

scientific article published on 15 April 2019

Reply to: "Diagnostic and prognostic role of circulating microparticles in hepatocellular carcinoma".

scientific article published in September 2017

SOX17 regulates cholangiocyte differentiation and acts as a tumor suppressor in cholangiocarcinoma.

scientific article published on 22 February 2017

Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage

scientific article published on 7 December 2022

Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma.

scientific article published on 26 May 2017

Serum metabolites as diagnostic biomarkers for cholangiocarcinoma, hepatocellular carcinoma and primary sclerosing cholangitis

scientific article published on 14 February 2019

Severity in polycystic liver disease is associated with aetiology and female gender: Results of the International PLD Registry

scientific article published on 08 October 2018

Shared apical sorting of anion exchanger isoforms AE2a, AE2b1, and AE2b2 in primary hepatocytes.

scientific article

Synergistic effects of extracellular vesicle phenotyping and AFP in hepatobiliary cancer differentiation

scientific article published on 02 July 2020

TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms

scientific article published on 09 September 2020

The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD).

scientific article

The effects of metabolic status on non-alcoholic fatty liver disease-related outcomes, beyond the presence of obesity

scientific article published on 23 October 2018

The search for novel diagnostic and prognostic biomarkers in cholangiocarcinoma

scientific article

The significance of genetics for cholangiocarcinoma development

scientific article

Towards Personalized Medicine for Intrahepatic Cholangiocarcinoma: Pharmacogenomic Stratification of Patients

scientific article published on 2 February 2018

Up-regulation of microRNA 506 leads to decreased Cl-/HCO3- anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis.

scientific article

Ursodeoxycholic acid in advanced polycystic liver disease: A phase 2 multicenter randomized controlled trial

scientific article published on 17 May 2016

Ursodeoxycholic acid inhibits hepatic cystogenesis in experimental models of polycystic liver disease.

scientific article

Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat.

scientific article

Wnt-β-catenin signalling in liver development, health and disease

scientific article published on 01 February 2019

Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure.

scientific article

miRNA-21 ablation protects against liver injury and necroptosis in cholestasis.

scientific article published on 11 December 2017

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