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List of works by Charles G. Glabe

A specific amyloid-beta protein assembly in the brain impairs memory

scientific journal article published in 2006. 14 July 2022 Editor’s Note: readers are advised to use caution when using results reported therein.

Amyloid Beta Annular Protofibrils in Cell Processes and Synapses Accumulate with Aging and Alzheimer-Associated Genetic Modification ⬇️

scientific article published on July 14, 2009

Amyloid-beta peptide and oligomers in the brain and cerebrospinal fluid of aged canines

scientific article

Amyloid-β Annular Protofibrils Evade Fibrillar Fate in Alzheimer Disease Brain ⬇️

scientific article published on April 20, 2011

An "epitomic" analysis of the specificity of conformation-dependent, anti-Aß amyloid monoclonal antibodies

scientific article published on 09 December 2020

Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer

scientific article

Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro.

scientific article published on February 2006

Atomic View of a Toxic Amyloid Small Oligomer

scientific article

Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity

scientific article published on 03 January 2017

Atomic-resolution structure of a disease-relevant Aβ(1-42) amyloid fibril

scientific article

Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity

scientific article

CD45 Deficiency Drives Amyloid-β Peptide Oligomers and Neuronal Loss in Alzheimer's Disease Mice ⬇️

scientific article published on January 26, 2011

Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

scientific article

Common mechanisms of amyloid oligomer pathogenesis in degenerative disease

scientific article

Conformation-dependent antibodies target diseases of protein misfolding

scientific article published in October 2004

Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers ⬇️

scientific article published on August 24, 2012

Cultured cell and transgenic mouse models for tau pathology linked to beta-amyloid

scientific article

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

scientific article (publication date: 18 February 2005)

Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers

scientific article

Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules

scientific article

Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces behavioral and Aβ pathology and modulates Aβ oligomerization

scientific article

Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers

scientific article

Effect of synthetic aβ peptide oligomers and fluorinated solvents on Kv1.3 channel properties and membrane conductance

scientific article

Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway

scientific article

Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy

scholarly article

Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes

scientific article

Fibrillar oligomers nucleate the oligomerization of monomeric amyloid beta but do not seed fibril formation

scientific article

Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin

scientific article published in 2008

Heat‐shock protein 70 modulates toxic extracellular α‐synuclein oligomers and rescues trans‐synaptic toxicity ⬇️

scientific article published on September 27, 2010

Hsp70 and Hsp40 Functionally Interact with Soluble Mutant Huntingtin Oligomers in a Classic ATP-dependent Reaction Cycle ⬇️

scientific article published on September 23, 2010

Hypertension is associated with preamyloid oligomers in human atrium: a missing link in atrial pathophysiology?

scientific article

Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques

scientific article

Linear and conformation specific antibodies in aged beagles after prolonged vaccination with aggregated Abeta

scientific article

Monoclonal antibodies against Aβ42 fibrils distinguish multiple aggregation state polymorphisms in vitro and in Alzheimer disease brain

scientific article

Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease

scientific article

Out-of-register  -sheets suggest a pathway to toxic amyloid aggregates

scientific article

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β.

scientific article

Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins

scientific article

Protective effect of geranylgeranylacetone via enhancement of HSPB8 induction in desmin-related cardiomyopathy

scientific article

Quantitative Imaging of Preamyloid Oligomers, a Novel Structural Abnormality, in Human Atrial Samples

scientific article

Reactive γ-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells

scientific article

Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy

scientific article

Soluble Abeta oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in Alzheimer's disease brain

scientific article

Soluble and mature amyloid fibrils in drusen deposits

scientific article

Structural classification of toxic amyloid oligomers

scientific article

Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice

scientific article

Tau-dependent microtubule disassembly initiated by prefibrillar beta-amyloid

scientific article

Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice

scientific article

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