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List of works by Georgios Giamas

A revised nomenclature for the lemur family of protein kinases

scientific article published in 2024

ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation.

scientific article published on 30 March 2016

Astrocytes, the rising stars of the glioblastoma microenvironment

scientific article published on 21 September 2018

Broader implications of SILAC-based proteomics for dissecting signaling dynamics in cancer

scientific article

CK1delta modulates the transcriptional activity of ERalpha via AIB1 in an estrogen-dependent manner and regulates ERalpha-AIB1 interactions.

scientific article published on April 2009

Cancer Gene Therapy: vision and strategy for the new decade

scientific article published on 18 February 2020

Casein kinase 1 delta (CK1delta) interacts with the SNARE associated protein snapin

scientific journal article

Characterization of the Tyrosine Kinase-Regulated Proteome in Breast Cancer by Combined use of RNA interference (RNAi) and Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) Quantitative Proteomics.

scientific article

Claudin-1 as a promoter of EMT in hepatocellular carcinoma.

scientific article published on 14 January 2013

Confirming size-exclusion chromatography as a clinically relevant extracellular vesicles separation method from 1mL plasma through a comprehensive comparison of methods

scientific article published in 2024

Correction: MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma.

scientific article published on 22 June 2017

Direct Effects of Anti-Angiogenic Therapies on Tumor Cells: VEGF Signaling.

scientific article

EGF and IGF1 affect sunitinib activity in BP-NEN: new putative targets beyond VEGFR?

scientific article published on 01 June 2019

Endocrine Resistance in Hormone Receptor Positive Breast Cancer-From Mechanism to Therapy.

scientific article published on 24 May 2019

Extracellular vesicles swarm the cancer microenvironment: from tumor-stroma communication to drug intervention.

scientific article

Genetic variants of kinase suppressors of Ras (KSR1) to predict survival in patients with ERα-positive advanced breast cancer.

scientific article

Insulin-like growth factor receptor polymorphism defines clinical outcome in estrogen receptor-positive breast cancer patients treated with tamoxifen.

scientific article published on 5 March 2013

KSR1 regulates BRCA1 degradation and inhibits breast cancer growth

scientific article

Kinases as targets in the treatment of solid tumors.

scientific article published on 21 January 2010

Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer.

scientific article published on 22 May 2011

Kinome‐Wide Synthetic Lethal Screen Identifies PANK4 as a Modulator of Temozolomide Resistance in Glioblastoma

scientific article published in 2024

LMTK3 Represses Tumor Suppressor-like Genes through Chromatin Remodeling in Breast Cancer

scientific article published on 23 July 2015

LMTK3 confers chemo-resistance in breast cancer.

scientific article published on 15 March 2018

LMTK3 escapes tumour suppressor miRNAs via sequestration of DDX5.

scientific article published on 28 December 2015

LMTK3 expression in breast cancer: association with tumor phenotype and clinical outcome.

scientific article published on 14 June 2011

LMTK3 is implicated in endocrine resistance via multiple signaling pathways.

scientific article

MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma.

scientific article published on 21 January 2014

MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors

scientific article (publication date: 2012)

Nicastrin regulates breast cancer stem cell properties and tumor growth in vitro and in vivo

scientific article

Phosphorylation of CK1delta: identification of Ser370 as the major phosphorylation site targeted by PKA in vitro and in vivo

scientific article

Protein kinases as targets for cancer treatment.

scientific article published on August 2007

Proteome-wide dataset supporting functional study of tyrosine kinases in breast cancer

scientific article

Proteomic profile of KSR1-regulated signalling in response to genotoxic agents in breast cancer.

scientific article published on 29 May 2015

Reply: When does a human being die?

scientific article published on 25 September 2015

SILAC-based phosphoproteomics reveals an inhibitory role of KSR1 in p53 transcriptional activity via modulation of DBC1.

scientific article published on 15 October 2013

Shedding of bevacizumab in tumour cells-derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma.

scientific article

Strategies in functional proteomics: Unveiling the pathways to precision oncology.

scientific article

Targeting lemurs against cancer metastasis

scientific article published on July 2014

Targeting tumor-stroma crosstalk: the example of the NT157 inhibitor.

scientific article published on 19 October 2015

The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response.

scientific article published on 24 August 2009

The kinase LMTK3 promotes invasion in breast cancer through GRB2-mediated induction of integrin β₁.

scientific article

The many-faced KSR1: a tumor suppressor in breast cancer.

scientific article

The phosphorylated membrane estrogen receptor and cytoplasmic signaling and apoptosis proteins in human breast cancer.

scientific article published in September 2008

The potential role of cyclooxygenase-2 (COX-2) during early breast cancer therapy

scientific article published on 06 May 2011

The role of pseudokinases in cancer.

scientific article published on 04 February 2012

The structure-function relationship of oncogenic LMTK3

scientific article published on 13 November 2020

Three Method-Combination Protocol for Improving Purity of Extracellular Vesicles

scientific article published on 27 April 2020

Tumor-Stromal Cell Communication: Small Vesicles Signal Big Changes

scientific article published on 11 June 2016

When does a human being die?

scientific article

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