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List of works by Chad A Brautigam

A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex

scientific article

An isolated CLASP TOG domain suppresses microtubule catastrophe and promotes rescue

scientific article published on 05 April 2018

Aromatic L-amino acid decarboxylase deficiency with hyperdopaminuria. Clinical and laboratory findings in response to different therapies.

scientific article published in August 2002

Autoinhibition of Munc18-1 modulates synaptobrevin binding and helps to enable Munc13-dependent regulation of membrane fusion.

scientific article published on 6 May 2017

Biocalorimetry

scientific article published on 01 April 2015

Biophysical and Biochemical Characterization of TP0037, a d-Lactate Dehydrogenase, Supports an Acetogenic Energy Conservation Pathway in Treponema pallidum

scientific article published on 22 September 2020

Biophysical insights into a highly selective l-arginine-binding lipoprotein of a pathogenic treponeme

scientific article published on 27 October 2018

Correction to: Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study

scientific article published in 2021

Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands

scientific article published on 19 September 2019

Design principles of a microtubule polymerase.

scientific article

Determination of protein complex stoichiometry through multisignal sedimentation velocity experiments.

scientific article

Enhanced Sample Handling for Analytical Ultracentrifugation with 3D-Printed Centerpieces

scientific article published on 15 April 2019

Evaluating the stoichiometry of macromolecular complexes using multisignal sedimentation velocity.

scientific article

Evidence for an ABC-Type Riboflavin Transporter System in Pathogenic Spirochetes

scientific article

Fast and Robust Quantification of Detergent Micellization Thermodynamics from Isothermal Titration Calorimetry

scientific article published on 27 December 2019

Fucosylated Molecules Competitively Interfere with Cholera Toxin Binding to Host Cells.

scientific article published on 7 February 2018

High-precision isothermal titration calorimetry with automated peak-shape analysis.

scientific article

Identification of a core sequence for the binding of BosR to the rpoS promoter region in Borrelia burgdorferi

scientific article published on 01 April 2015

Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone

scientific article published on 11 March 2019

Improving the thermal, radial, and temporal accuracy of the analytical ultracentrifuge through external references

scientific article published on 24 May 2013

Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions

scientific article

Methods for analysis of ligand-induced RNA conformational changes

scientific article published on 01 January 2009

Moraxella catarrhalis synthesizes an autotransporter that is an acid phosphatase.

scientific article published on 7 December 2007

Overview of current methods in sedimentation velocity and sedimentation equilibrium analytical ultracentrifugation.

scientific article published on February 2013

Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites

scientific article published on 26 September 2017

SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.

scientific article published on 24 October 2017

Structural and Thermodynamic Basis for Weak Interactions between Dihydrolipoamide Dehydrogenase and Subunit-binding Domain of the Branched-chain  -Ketoacid Dehydrogenase Complex

scientific article

Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes.

scientific article published on February 1998

Structural basis of arrestin-3 activation and signaling.

scientific article published on 10 November 2017

Structural determinants of nuclear export signal orientation in binding to exportin CRM1.

scientific article

Structural elucidation of the binding and inhibitory properties of lanthanide (III) ions at the 3'-5' exonucleolytic active site of the Klenow fragment

scientific article

Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex

scientific article

Subunit and catalytic component stoichiometries of an in vitro reconstituted human pyruvate dehydrogenase complex

scientific article

The Cdc20-binding Phe box of the spindle checkpoint protein BubR1 maintains the mitotic checkpoint complex during mitosis

scientific article

The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop

scientific article

The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores

scientific article

Using modern approaches to sedimentation velocity to detect conformational changes in proteins

scientific article published on 05 August 2020