List of works by Josephine H Cox

A DNA-based candidate HIV vaccine delivered via in vivo electroporation induces CD4 responses toward the α4β7-binding V2 loop of HIV gp120 in healthy volunteers

scientific article published on 25 July 2012

A New Multi-clade DNA Prime/Recombinant MVA Boost Vaccine Induces Broad and High Levels of HIV-1-specific CD8+ T-cell and Humoral Responses in Mice

article

A Phase 1 Study of 4 Live, Recombinant Human Cytomegalovirus Towne/Toledo Chimera Vaccines in Cytomegalovirus-Seronegative Men

scientific article published on 11 August 2016

A Phase 1 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 subtype C-modified vaccinia Ankara virus vaccine candidate in Indian volunteers

scientific article published in November 2009

A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of Electroporated HIV DNA with or without Interleukin 12 in Prime-Boost Combinations with an Ad35 HIV Vaccine in Healthy HIV-Seronegative African Adults

scientific article published on 7 August 2015

A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of an Adjuvanted HIV-1 Gag-Pol-Nef Fusion Protein and Adenovirus 35 Gag-RT-Int-Nef Vaccine in Healthy HIV-Uninfected African Adults

scientific article published on 11 May 2015

A double-blind randomized phase I clinical trial targeting ALVAC-HIV vaccine to human dendritic cells

scientific article published on 16 September 2011

A high viral burden predicts the loss of CD8 T-cell responses specific for subdominant gag epitopes during chronic human immunodeficiency virus infection

scientific article

A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays

scientific article published on 01 February 2002

A phase 1/2 study of a multiclade HIV-1 DNA plasmid prime and recombinant adenovirus serotype 5 boost vaccine in HIV-Uninfected East Africans (RV 172).

scientific article

A phase 2 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 vaccine based on adeno-associated virus

scientific article published in August 2010

A phase I double blind, placebo-controlled, randomized study of a multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults

scientific article

Adeno-associated virus vectored immunoprophylaxis to prevent HIV in healthy adults: a phase 1 randomised controlled trial

article

Adenovirus-based HIV-1 vaccine candidates tested in efficacy trials elicit CD8+ T cells with limited breadth of HIV-1 inhibition

scientific article published on 14 April 2016

An influenza vaccine pill-can we swallow it?

scientific article published on September 2015

Antibody-dependent cell-mediated cytotoxic responses in participants enrolled in a phase I/II ALVAC-HIV/AIDSVAX B/E prime-boost HIV-1 vaccine trial in Thailand

scientific article published on 01 March 2005

Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development

scientific article published on August 2006

Assessment of Anti-HIV-1 Antibodies in Oral and Nasal Compartments of Volunteers From 3 Different Populations

scientific article

Assessment of the Safety and Immunogenicity of 2 Novel Vaccine Platforms for HIV-1 Prevention: A Randomized Trial

scientific article published on 02 February 2016

Broad HIV epitope specificity and viral inhibition induced by multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults

scientific article

Broad HIV-1 inhibition in vitro by vaccine-elicited CD8(+) T cells in African adults

scientific article published on 31 August 2016

Broad immunogenicity of a multigene, multiclade HIV-1 DNA vaccine boosted with heterologous HIV-1 recombinant modified vaccinia virus Ankara

scientific article published on November 2008

CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients

scientific article published on 20 December 2006

CTL epitope distribution patterns in the Gag and Nef proteins of HIV-1 from subtype A infected subjects in Kenya: use of multiple peptide sets increases the detectable breadth of the CTL response.

scientific article

Circulating and unique recombinant forms of HIV type 1 containing subsubtype A2.

scientific article

Comprehensive screening for human immunodeficiency virus type 1 subtype-specific CD8 cytotoxic T lymphocytes and definition of degenerate epitopes restricted by HLA-A0207 and -C(W)0304 alleles

scientific article

Concordant proficiency in measurement of T-cell immunity in human immunodeficiency virus vaccine clinical trials by peripheral blood mononuclear cell and enzyme-linked immunospot assays in laboratories from three continents

scientific article published on 17 December 2008

Cryopreservation-related loss of antigen-specific IFNγ producing CD4+ T-cells can skew immunogenicity data in vaccine trials: Lessons from a malaria vaccine trial substudy

scientific article

Design and evaluation of multi-gene, multi-clade HIV-1 MVA vaccines

scientific article published on 03 August 2009

Detection of high frequencies of HIV-1 cross-subtype reactive CD8 T lymphocytes in the peripheral blood of HIV-1-infected Kenyans

scientific article published on October 2003

Development of a luciferase based viral inhibition assay to evaluate vaccine induced CD8 T-cell responses

scientific article

Effect of a Chikungunya Virus-Like Particle Vaccine on Safety and Tolerability Outcomes: A Randomized Clinical Trial

scientific article published on 01 April 2020

Endpoint Assays in HIV-1 Vaccine Trials: Functioning in a Good Laboratory Practices Environment

article

Equivalence of ELISpot assays demonstrated between major HIV network laboratories

scientific article

Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials

scientific article

Evaluation and recommendations on good clinical laboratory practice guidelines for phase I-III clinical trials

scientific article

Evaluation of natural killer cell activity

scientific article published on 01 June 2000

Evaluation of natural killer cell activity

scientific article published on 01 January 1999

First-in-Human Evaluation of the Safety and Immunogenicity of an Intranasally Administered Replication-Competent Sendai Virus-Vectored HIV Type 1 Gag Vaccine: Induction of Potent T-Cell or Antibody Responses in Prime-Boost Regimens

scientific article published on 17 October 2016

HIV-1 MN Env 15-mer peptides better detect HIV-1 specific CD8 T cell responses compared with consensus subtypes B and M group 15-mer peptides

scientific article published in July 2005

HIV-1-Specific Antibody-Dependent Cellular Cytotoxicity (ADCC).

scientific article

HIV-1-Specific Cytotoxic T-Cell Assays

scientific article published on 01 January 1999

HLA-A and -B allele expression and ability to develop anti-Gag cross-clade responses in subtype C HIV-1-infected Ethiopians

scientific article published in June 2004

Heterologous prime-boost regimens using rAd35 and rMVA vectors elicit stronger cellular immune responses to HIV proteins than homologous regimens

scientific article

Identification of a novel HIV type 1 CRF01_AE cytotoxic T lymphocyte (CTL) epitope restricted by an HLA-Cw0602 allele and a novel HLA-A0206/peptide restriction

scientific article published on 01 December 2006

Immune activation alters cellular and humoral responses to yellow fever 17D vaccine

scientific article

Immune reconstitution following autologous transfers of CD3/CD28 stimulated CD4(+) T cells to HIV-infected persons

scientific article published in June 2004

Immunodominance and Cross-Reactivity of B5703-Restricted CD8 T Lymphocytes from HIV Type 1 Subtype C-Infected Ethiopians

article

In a mixed subtype epidemic, the HIV-1 Gag-specific T-cell response is biased towards the infecting subtype

scientific article

In vivo electroporation enhances the immunogenicity of an HIV-1 DNA vaccine candidate in healthy volunteers

scientific article (publication date: 2011)

Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge

scientific article published on 9 January 2012

Induction of HIV-specific functional immune responses by a multiclade HIV-1 DNA vaccine candidate in healthy Ugandans

scientific article published on 17 September 2007

Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials

scientific article

Long-term follow-up of study participants from prophylactic HIV vaccine clinical trials in Africa

scientific article

Longitudinal study of humoral immune responses in HIV type 1 subtype CRF01_AE (E)-infected Thai patients with different rates of disease progression

scientific article published on April 2003

Lost in translation: implications of HIV-1 codon usage for immune escape and drug resistance.

scientific article published on January 2004

Lymphocyte traffic in pregnant or oestrogen stimulated rats

scientific article published on 01 May 1984

Magnitude, breadth, and functional profile of T-cell responses during human immunodeficiency virus primary infection with B and BF viral variants

scientific article

Measurement of cytokine release at the single cell level using the ELISPOT assay

scientific article published on April 2006

Multiplexed FluoroSpot for the Analysis of Dengue Virus- and Zika Virus-Specific and Cross-Reactive Memory B Cells

article

Orientation of epitopes influences the immunogenicity of synthetic peptide dimers

scientific article published on 01 December 1988

Peptide impurities in commercial synthetic peptides and their implications for vaccine trial assessment

scientific article

Phase 1 safety and immunogenicity evaluation of ADMVA, a multigenic, modified vaccinia Ankara-HIV-1 B'/C candidate vaccine

scientific article

Phase 1 safety and immunogenicity evaluation of ADVAX, a multigenic, DNA-based clade C/B' HIV-1 candidate vaccine

scientific article

Phase I safety and immunogenicity evaluation of MVA-CMDR, a multigenic, recombinant modified vaccinia Ankara-HIV-1 vaccine candidate

scientific article

Phase I study of safety and immunogenicity of an Escherichia coli-derived recombinant protective antigen (rPA) vaccine to prevent anthrax in adults

scientific article

Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells

scientific article published on 7 October 2002

Prior Dengue virus exposure shapes T cell immunity to Zika virus in humans

scientific article published on 4 October 2017

Quality monitoring of HIV-1-infected and uninfected peripheral blood mononuclear cell samples in a resource-limited setting

scientific article

Recombinant Modified Vaccinia Ankara (MVA) effectively boosts DNA-primed HIV-specific immune responses in humans despite pre-existing vaccinia immunity

scientific article published on 29 May 2009

Results of an ELISPOT proficiency panel conducted in 11 laboratories participating in international human immunodeficiency virus type 1 vaccine trials

scientific article published in January 2005

Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentation ⬇️

scientific article published on December 1, 1991

Safety and Immunogenicity of a Randomized Phase 1 Prime-Boost Trial With ALVAC-HIV (vCP205) and Oligomeric Glycoprotein 160 From HIV-1 Strains MN and LAI-2 Adjuvanted in Alum or Polyphosphazene

scientific article published on 11 February 2016

Safety and immunogenicity of DNA and MVA HIV-1 subtype C vaccine prime-boost regimens: a phase I randomised Trial in HIV-uninfected Indian volunteers

scientific article

Safety and immunogenicity of DNA prime and modified vaccinia ankara virus-HIV subtype C vaccine boost in healthy adults.

scientific article published on 23 January 2013

Safety and immunogenicity study of Multiclade HIV-1 adenoviral vector vaccine alone or as boost following a multiclade HIV-1 DNA vaccine in Africa

scientific article (publication date: 21 September 2010)

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

scientific article published on 4 December 2017

Standardization and validation issues of the ELISPOT assay

scientific article published on 01 January 2005

Standardization of cytokine flow cytometry assays

scientific article

The 65kDa antigen of mycobacteria-a common bacterial protein?

scientific article published in January 1987

The External Quality Assurance Oversight Laboratory (EQAPOL) proficiency program for IFN-gamma enzyme-linked immunospot (IFN-γ ELISpot) assay

scientific article

The effects of cyclosporin on lymphocyte activation in a systemic graft-vs.-host reaction

scientific article published on 01 October 1985

The kinetics and specificity of lymphocyte infiltration of cardiac allografts in unmodified and cyclosporin-treated rats ⬇️

scientific article published on 01 July 1984

The migration of lymphocytes across specialized vascular endothelium. IV. Prednisolone acts at several points on the recirculation pathways of lymphocytes

scientific article published on 01 January 1982

Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.

scientific article published on 31 October 2013

Varicella zoster virus--specific immune response after treatment with sodium stibogluconate for cutaneous leishmaniasis

scientific article published in March 2008

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