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List of works by Jeroen Pasterkamp

A double hit implicates DIAPH3 as an autism risk gene.

scientific article published on 23 March 2010

A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy

scientific article published on 24 June 2020

ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization

scientific article published on 19 May 2020

An Image-Based miRNA screen identifies miRNA-135s as regulators of CNS axon growth and regeneration by targeting Krüppel-like factor 4.

scientific article published in December 2017

Anatomical distribution of the chemorepellent semaphorin III/collapsin-1 in the adult rat and human brain: Predominant expression in structures of the olfactory-hippocampal pathway and the motor system ⬇️

scientific article published on April 1, 1998

Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis

scientific article published on December 2011

Antagonizing Increased miR-135a Levels at the Chronic Stage of Experimental TLE Reduces Spontaneous Recurrent Seizures

scientific article published on 23 April 2019

Axon guidance in the dopamine system.

scientific article published on January 2009

Axon guidance proteins in neurological disorders.

scientific article published on 11 March 2015

C9orf72 ablation in mice does not cause motor neuron degeneration or motor deficits

scientific article published on 5 June 2015

C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis

scientific article

CFEOM1-associated kinesin KIF21A is a cortical microtubule growth inhibitor.

scientific article published on 10 October 2013

Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment

scientific article published on 14 August 2017

Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

preprint

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

scholarly article

DeActs: genetically encoded tools for perturbing the actin cytoskeleton in single cells.

scientific article published on 10 April 2017

Detailed analysis of the genetic and epigenetic signatures of iPSC-derived mesodiencephalic dopaminergic neurons.

scientific article published on 3 April 2014

Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures

scientific article (publication date: 2013)

Differential expression of estrogen receptor mRNA and protein in the female rat preoptic area ⬇️

scientific article published on December 19, 1997

Disrupted neuronal trafficking in amyotrophic lateral sclerosis

scientific article published on 05 February 2019

Dysregulation of Semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility

scientific article

Emerging roles for semaphorins in neural regeneration

scientific article published on 01 March 2001

Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats.

scientific article

Exposure to the Amino Acids Histidine, Lysine, and Threonine Reduces mTOR Activity and Affects Neurodevelopment in a Human Cerebral Organoid Model

scientific article published on 23 May 2022

FUS mutations in familial amyotrophic lateral sclerosis in the Netherlands.

scientific article published in February 2010

Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development.

scientific article published on October 2015

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

scientific article published on 25 July 2016

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis

scientific article

Genome-wide microRNA profiling of human temporal lobe epilepsy identifies modulators of the immune response

scientific article

Getting connected in the dopamine system.

scientific article published on 20 January 2008

Getting neural circuits into shape with semaphorins ⬇️

scientific article published on August 16, 2012

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.

scientific article

High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling molecule

scientific article

Kinetic and spectroscopic characterization of the putative monooxygenase domain of human MICAL-1

scientific article

Long non-coding RNAs in motor neuron development and disease

scientific article published on 24 September 2020

MICAL flavoprotein monooxygenases: expression during neural development and following spinal cord injuries in the rat.

scientific article published on 17 October 2005

MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis

scientific article

MICALs in control of the cytoskeleton, exocytosis, and cell death ⬇️

scientific article published on 06 August 2011

MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion

scientific article (publication date: 28 June 2002)

MeCP2 deficiency disrupts axonal guidance, fasciculation, and targeting by altering Semaphorin 3F function.

scientific article published on 21 July 2009

Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development

scientific article

NIPA1 polyalanine repeat expansions are associated with amyotrophic lateral sclerosis

scientific article published on 28 February 2012

Neuromuscular Junction-on-a-Chip: ALS disease modeling and read-out development in microfluidic devices

scientific article published on 31 December 2020

Neuropeptide delivery to the brain: a von Willebrand factor signal peptide to direct neuropeptide secretion.

scientific article

Nolz1 expression is required in dopaminergic axon guidance and striatal innervation

scientific article published on 19 June 2020

Peripheral nerve injury fails to induce growth of lesioned ascending dorsal column axons into spinal cord scar tissue expressing the axon repellent Semaphorin3A.

scientific article published in February 2001

Protein aggregation in amyotrophic lateral sclerosis.

scientific article published on 15 May 2013

R-Ras fills another GAP in semaphorin signalling

scientific article published on 01 February 2005

Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers

scientific article published on 19 May 2011

Regulation of semaphorin III/collapsin-1 gene expression during peripheral nerve regeneration.

scientific article published in October 1998

Repulsive guidance molecule a (RGMa) induces neuropathological and behavioral changes that closely resemble Parkinson's disease.

scientific article published on 21 August 2017

S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration.

scientific article published on 28 January 2013

Semaphorin 7A Promotes Chemokine-Driven Dendritic Cell Migration

scientific article published on 23 November 2015

Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin

scientific journal article

Semaphorin function in neural plasticity and disease.

scientific article published on 21 June 2009

Semaphorin junction: making tracks toward neural connectivity

scientific journal article

Semaphorin signaling: progress made and promises ahead.

scientific article published on April 2008

Semaphorin signalling during development

scientific article

Semaphorin7A and its receptors: Pleiotropic regulators of immune cell function, bone homeostasis, and neural development ⬇️

scientific article published on January 16, 2013

Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence

scientific article

Sensory Axon Growth Requires Spatiotemporal Integration of CaSR and TrkB Signaling

scientific article published on 23 May 2019

Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors

scientific article published on 24 February 2022

SnapShot: Axon Guidance ⬇️

scientific article published on April 11, 2013

SnapShot: Axon Guidance II ⬇️

scientific article published on April 25, 2013

Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively

scientific article published on 03 March 2005

Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain.

scientific article

Structural basis of semaphorin-plexin cis interaction

scientific article published on 05 June 2020

Structure of the Repulsive Guidance Molecule (RGM)-Neogenin Signaling Hub

scientific article

Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula

scientific article published in July 2014

TRPC3 is a major contributor to functional heterogeneity of cerebellar Purkinje cells

scientific article published on 05 September 2019

Taking a risk: a therapeutic focus on ataxin-2 in amyotrophic lateral sclerosis?

scientific article published on 16 October 2013

The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections

scientific journal article

Transcriptional repression of Plxnc1 by Lmx1a and Lmx1b directs topographic dopaminergic circuit formation.

scientific article published on 16 October 2017

UNC13A is a modifier of survival in amyotrophic lateral sclerosis

scientific article published on 25 November 2011

VCP mutations in familial and sporadic amyotrophic lateral sclerosis

scientific article published on 10 November 2011

Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem

scientific journal article

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.

scientific article

shRNA-induced saturation of the microRNA pathway in the rat brain.

scientific article published on 2 January 2014

unc5c haploinsufficient phenotype: striking similarities with the dcc haploinsufficiency model.

scientific article published on 5 June 2013

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