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List of works by Marc Caron

"To learn, you must pay attention." Molecular insights into teachers' wisdom

scientific article

125I-labeled p-azidobenzylcarazolol, a photoaffinity label for the beta-adrenergic receptor. Characterization of the ligand and photoaffinity labeling of beta 1- and beta 2-adrenergic receptors

scientific article published on October 1982

5-HT1A and histamine H1 receptors in HeLa cells stimulate phosphoinositide hydrolysis and phosphate uptake via distinct G protein pools.

scientific article published on January 1991

A Brief History of the β-Arrestins

scientific article published on 01 January 2019

A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons.

scientific article published on 5 December 2012

A beta-arrestin 2 signaling complex mediates lithium action on behavior

scientific article

A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors

scientific article published on 30 November 2005

A cAMP response element in the beta 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP.

scientific article

A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion

scientific article published on 02 December 2019

A central role for beta-arrestins and clathrin-coated vesicle-mediated endocytosis in beta2-adrenergic receptor resensitization. Differential regulation of receptor resensitization in two distinct cell types

scientific article published on October 1997

A dopamine D1 receptor-dependent β-arrestin signaling complex potentially regulates morphine-induced psychomotor activation but not reward in mice

scientific article

A family of receptors coupled to guanine nucleotide regulatory proteins

scientific article published on 01 May 1987

A functional alternative splicing mutation in human tryptophan hydroxylase-2.

scientific article

A greater role for the norepinephrine transporter than the serotonin transporter in murine nociception

scientific article

A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated beta 2-adrenergic receptor sequestration

scientific article published on 01 January 1994

A murine model of hyperdopaminergic state displays altered respiratory control

scientific article published on 25 January 2007

A mutation of the beta 2-adrenergic receptor impairs agonist activation of adenylyl cyclase without affecting high affinity agonist binding. Distinct molecular determinants of the receptor are involved in physical coupling to and functional activati

scientific article published on January 1990

A novel radioiodinated high affinity ligand for the D2-dopamine receptor. Characterization of its binding in bovine anterior pituitary membranes

scientific article published in October 1984

A rapid and affordable screening platform for membrane protein trafficking.

scientific article

A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression

scientific article published on 13 March 2008

A role for Ni in the hormonal stimulation of adenylate cyclase

scientific article published in Nature

A role for receptor kinases in the regulation of class II G protein-coupled receptors. Phosphorylation and desensitization of the secretin receptor

scientific article (publication date: 20 March 1998)

A small region of the beta-adrenergic receptor is selectively involved in its rapid regulation ⬇️

scientific article published on April 15, 1991

A β-Arrestin/Green Fluorescent Protein Biosensor for Detecting G Protein-coupled Receptor Activation ⬇️

scientific article published on October 31, 1997

A2a/D2 receptor interactions are not observed in COS-7 cells transiently transfected with dopamine D2 and adenosine A2a receptor cDNA.

scientific article published on November 1994

Aberrant responses in social interaction of dopamine transporter knockout mice

scientific article published on January 2004

Adenylate cyclase-coupled beta-adrenergic receptors: structure and mechanisms of activation and desensitization

scientific article published on January 1983

Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis

scientific article published on 03 July 2019

Adjunctive 5-Hydroxytryptophan Slow-Release for Treatment-Resistant Depression: Clinical and Preclinical Rationale

scientific article published on 28 September 2016

Adrenergic receptor homologies in vertebrate and invertebrate species examined by DNA hybridization

scientific article published in January 1989

Adrenergic receptors

scientific article published on 01 January 1990

Adrenergic receptors

scientific article published on 01 January 1988

Adrenergic receptors. Models for regulation of signal transduction processes

scientific article published on February 1990

Adrenergic receptors. Models for the study of receptors coupled to guanine nucleotide regulatory proteins

scientific article published on April 1988

Adrenergic receptors: molecular mechanisms of clinically relevant regulation

scientific article

Adrenergic receptors: recent insights into their mechanism of activation and desensitization.

scientific article published on January 1993

Advancing drug discovery for schizophrenia

scientific article

Affinity chromatography of human platelet alpha 2-adrenergic receptors

scientific article

Affinity chromatography of the D1 dopamine receptor from rat corpus striatum ⬇️

scientific article published on May 31, 1988

Affinity chromatography of the anterior pituitary D2-dopamine receptor

scientific article published in February 1986

Affinity chromatography of the beta-adrenergic receptor ⬇️

scientific article published on April 25, 1979

Affinity chromatography of the beta-adrenergic receptor and characterization of antibodies raised against purified receptor preparations

scientific article published on 01 January 1980

Agonist binding promotes a guanine nucleotide reversible increase in the apparent size of the bovine anterior pituitary dopamine receptors

scientific article

Agonist-Induced Desensitization of the D-2 Dopamine Receptor in the Intermediate Lobe of the Rat Pituitary Gland ⬇️

scientific article published on March 1, 1988

Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase

scientific article published on 01 December 1987

Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by beta-adrenergic receptor kinase 1. A role in receptor sequestration

scientific article published on 19 March 2001

Agonist-modulated palmitoylation of beta 2-adrenergic receptor in Sf9 cells ⬇️

scientific article published on October 25, 1992

Agonist-specific regulation of delta-opioid receptor trafficking by G protein-coupled receptor kinase and beta-arrestin

scientific article published on January 1999

Akt/GSK3 signaling in the action of psychotropic drugs

scientific article published on January 2009

Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene

scientific article published on May 1990

Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3

scientific article

Altered patterns of agonist-stimulated cAMP accumulation in cells expressing mutant beta 2-adrenergic receptors lacking phosphorylation sites

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior

scientific article

An animal model of attention deficit hyperactivity disorder

scientific article published on 01 January 2000

An approach to the study of G-protein-coupled receptor kinases: an in vitro-purified membrane assay reveals differential receptor specificity and regulation by G beta gamma subunits

scientific article

An interaction between L-prostaglandin D synthase and arrestin increases PGD2 production

scientific article published on 26 November 2010

An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins

scientific article

Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions

scientific article

Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics.

scholarly article

Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter

scientific journal article

Antibodies raised against purified β-adrenergic receptors specifically bind β-adrenergic ligands ⬇️

scientific article published on May 1, 1979

Antibodies to the beta-adrenergic receptor: attenuation of catecholamine-sensitive adenylate cyclase and demonstration of postsynaptic receptor localization in brain

scientific article published on April 1983

Antiproliferative action of dopamine and norepinephrine in neuroblastoma cells expressing the human dopamine transporter

scientific article

Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors

scientific article published on October 2002

Application of microdialysis and voltammetry to assess dopamine functions in genetically altered mice: correlation with locomotor activity.

scientific article

Assignment of the creatine transporter gene (SLC6A8) to human chromosome Xq28 telomeric to G6PD.

scientific article

Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization

scientific article

Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice

scientific article published on September 2008

Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands

scientific article

Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice

scientific article

Behavioral responses to social stress in noradrenaline transporter knockout mice: effects on social behavior and depression.

scientific article

Behavioral, cellular and molecular consequences of the dopamine transporter gene inactivation

scientific article published in January 1998

Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor

scientific journal article

Beta-adrenergic receptor kinase: primary structure delineates a multigene family

scientific article

Beta-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids

scientific article published on 01 July 1988

Beta-adrenergic receptors: biochemical mechanisms of physiological regulation

scientific article published on April 1984

Beta-agonist- and prostaglandin E1-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors

scientific article published on September 1986

Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway

scientific article published in December 2004

Beta-arrestin goes nuclear

scientific article published on 01 December 2005

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

scientific article

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family ⬇️

scientific article published on September 5, 1992

Binding of [125I]-N-(p-aminophenethyl)spiroperidol to the D-2 dopamine receptor in the neurointermediate lobe of the rat pituitary gland: a thermodynamic study

scientific article published in February 1988

Binding of the opiate-like pentapeptide methionine-enkephalin to a particulate fraction from rat brain

scientific article published in December 1976

Biochemical characterization of the BETA-adrenergic receptor of the frog erythrocyte ⬇️

scientific article published on December 14, 1979

Biochemical characterization of the adrenergic receptors: affinity labeling, purification, and reconstitution studies.

scientific article

Biochemical properties of D1 and D2 dopamine receptors

scientific article

Biological activity of agarose-immobilized catecholamines ⬇️

scientific article (publication date: 24 September 1976)

Bone histomorphometric and biomechanical abnormalities in mice homozygous for deletion of the dopamine transporter gene

scientific article published on 01 January 2000

Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress

scientific article

Brain-region-specific Molecular Responses to Maternal Separation and Social Defeat Stress in Mice

scientific article published on 13 January 2018

Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability

scientific article published in March 2018

Building a new conceptual framework for receptor heteromers

scientific article

Cariprazine exerts antimanic properties and interferes with dopamine D2 receptor β-arrestin interactions

scientific article

Catecholamine receptors: structure, function, and regulation.

scientific article

Catecholamine release and uptake in the mouse prefrontal cortex

scientific article

Catecholamine transporters and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: studies comparing the cloned human noradrenaline and human dopamine transporter

scientific article published on 01 June 1996

Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor ⬇️

scientific article published on June 1, 1983

Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase. Structural alterations in the beta-adrenergic receptor revealed by photoaffinity labeling ⬇️

scientific article published on August 25, 1982

Catecholamine-induced subsensitivity of adenylate cyclase associated with loss of beta-adrenergic receptor binding sites ⬇️

scientific article published on May 1, 1975

Cellular trafficking of G protein-coupled receptor/beta-arrestin endocytic complexes

scientific article published on April 1999

Center stage for the serotonin transporter: a gain-of-function polymorphism in persons with obsessive-compulsive disorder

scientific article published in August 2003

Characteristics of 5'-guanylyl imidodiphosphate-activated adenylate cyclase ⬇️

scientific article published on June 25, 1975

Characterization of an atypical member of the Na+/Cl(-)-dependent transporter family: chromosomal localization and distribution in GABAergic and glutamatergic neurons in the rat brain.

scientific article published on February 1994

Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice

scientific article

Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D2 and D4 receptors

scientific article

Characterization of the radioiodinated analogue of SCH 23390: in vitro and in vivo D-1 dopamine receptor binding studies

scientific article

Chimeric D2/D3 dopamine receptors efficiently inhibit adenylyl cyclase in HEK 293 cells

scientific article

Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity

scientific article

Cholinergic dysfunction in the dorsal striatum promotes habit formation and maladaptive eating

scientific article published on 09 November 2020

Chromosomal organization of adrenergic receptor genes

scientific article

Chronic SSRI treatment exacerbates serotonin deficiency in humanized Tph2 mutant mice

scientific article published on October 2012

Chronic fluoxetine increases extra-hippocampal neurogenesis in adult mice

scientific article

Ciba-Geigy award for outstanding research. Regulation of adrenergic receptor function by phosphorylation

scientific article published in September 1986

Cloning and characterization of the opossum kidney cell D1 dopamine receptor: expression of identical D1A and D1B dopamine receptor mRNAs in opossum kidney and brain

scientific article published on November 1993

Cloning and expression of a functional serotonin transporter from rat brain

scientific article

Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype

scientific article

Cloning and functional characterization of a cocaine-sensitive dopamine transporter

scientific journal article

Cloning of the cDNA and genes for the hamster and human beta 2-adrenergic receptors

scientific article published on 01 January 1988

Cloning of the cDNA for the human beta 1-adrenergic receptor

scientific article

Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin

scientific article

Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes

scientific article

Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family

scientific journal article

Cloning, gene structure and genomic localization of an orphan transporter from mouse kidney with six alternatively-spliced isoforms

scientific journal article

Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor ⬇️

scientific article published on September 1, 1991

Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter.

scientific article published in September 1992

Cloning, pharmacological characterization, and genomic localization of the human creatine transporter

scientific article

Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor

scientific article

Cocaine and amphetamine elicit differential effects in rats with a unilateral injection of dopamine transporter antisense oligodeoxynucleotides

scientific article published on February 1997

Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions.

scientific article published in January 2002

Cocaine self-administration in dopamine-transporter knockout mice

scientific article

Cocaine-conditioned locomotion in dopamine transporter, norepinephrine transporter and 5-HT transporter knockout mice

scientific article

Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase ⬇️

scientific article published on July 15, 1991

Comparative studies of molecular mechanisms of dopamine D2 and D3 receptors for the activation of extracellular signal-regulated kinase

scientific article published on 21 April 2004

Complementary roles of the DRY motif and C-terminus tail of GPCRS for G protein coupling and beta-arrestin interaction

scientific article published on 26 November 2007

Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia

scientific article

Congenital brain serotonin deficiency leads to reduced ethanol sensitivity and increased ethanol consumption in mice

scientific article published on 22 September 2013

Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation ⬇️

scientific article published on January 25, 1992

Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus

scholarly article

Constitutive desensitization: a new paradigm for g protein-coupled receptor regulation

scientific article published on April 2003

Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network

scientific article

Constitutively active alpha-1b adrenergic receptor mutants display different phosphorylation and internalization features

scientific article published on February 1999

Control of Hormone Receptor Levels and Growth of 7,12-Dimethylbenz(a)anthracene-Induced Mammary Tumors by Estrogens, Progesterone and Prolactin ⬇️

scientific article published on September 1, 1977

Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice

scientific article published in July 1998

Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit

scientific article published on 01 October 1990

Correction: The Dopamine Metabolite 3-Methoxytyramine Is a Neuromodulator.

scientific article published on 28 October 2010

Correction: The Stem Cell-Expressed Receptor Lgr5 Possesses Canonical and Functionally Active Molecular Determinants Critical to β-arrestin-2 Recruitment.

scientific article published on 10 January 2014

Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency

scientific article published on March 2013

Coupling of a mutated form of the human beta 2-adrenergic receptor to Gi and Gs. Requirement for multiple cytoplasmic domains in the coupling process

scientific article published on 01 March 1991

Coupling of the expressed alpha 1B-adrenergic receptor to the phospholipase C pathway in Xenopus oocytes. The role of Go.

scientific article

Covalent labeling of the beta-adrenergic ligand-binding site with para-(bromoacetamidyl)benzylcarazolol. A highly potent beta-adrenergic affinity label

scientific article published on May 1985

Covalent labeling of the cerebral cortex alpha 1-adrenergic receptor with a new high affinity radioiodinated photoaffinity probe

scientific article published on September 1983

Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation

scientific article

Cyclic phosphorylation-dephosphorylation of rhodopsin in retina by protein kinase FA (the activator of ATP.Mg-dependent protein phosphatase)

scientific article published on 01 August 1991

D1 dopamine receptor binding and mRNA levels are not altered after neonatal 6-hydroxydopamine treatment: evidence against dopamine-mediated induction of D1 dopamine receptors during postnatal development

scientific article published in October 1993

D2 dopamine receptors in the human retina: Cloning of cDNA and localization of mRNA ⬇️

scientific article published on October 1, 1991

DDD mice, a novel acute mouse model of Parkinson's disease

scientific article published in October 2006

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice

scientific article

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice.

scientific article published on 17 February 2015

Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice ⬇️

scientific article published on May 3, 2011

Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D1 Receptor Agonists

scientific article published on 27 March 2019

Deletion of GSK3β in D2R-expressing neurons reveals distinct roles for β-arrestin signaling in antipsychotic and lithium action ⬇️

scientific article published on November 27, 2012

Deletion of Glycogen Synthase Kinase-3β in D2 Receptor-Positive Neurons Ameliorates Cognitive Impairment via NMDA Receptor-Dependent Synaptic Plasticity

scientific article published on 06 November 2019

Delineating muscarinic receptor functions

scientific article

Delineation of discrete domains for substrate, cocaine, and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters.

scientific article published in June 1994

Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions

scientific article published in May 1987

Dependence of Serotonergic and Other Nonadrenergic Enteric Neurons on Norepinephrine Transporter Expression ⬇️

scientific article published on December 8, 2010

Dephosphorylation of the beta 2-adrenergic receptor and rhodopsin by latent phosphatase 2

scientific article

Desensitization of DA1 dopamine receptors coupled to adenylyl cyclase in opossum kidney cells

scientific article published on June 1991

Desensitization of G protein-coupled receptors and neuronal functions

scientific article published in January 2004

Desensitization of the beta-adrenergic receptor of frog erythrocytes. Recovery and characterization of the down-regulated receptors in sequestered vesicles ⬇️

scientific article published on March 10, 1983

Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms

scientific article (publication date: 31 March 1992)

Desensitization of turkey erythrocyte adenylate cyclase. Beta-adrenergic receptor phosphorylation is correlated with attenuation of adenylate cyclase activity ⬇️

scientific article published on August 10, 1984

Desensitization, phosphorylation and palmitoylation of the human dopamine D1 receptor

scientific article published on March 1994

Design, synthesis and biological evaluation of GPR55 agonists

scientific article published on 13 June 2017

Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones

scientific article published on 16 February 2016

Designing Functionally Selective Noncatechol Dopamine D1 Receptor Agonists with Potent In Vivo Antiparkinsonian Activity

scientific article published on 20 August 2019

Detergents Linked to Polysaccharides: Preparation and Effects on Membranes and Cells ⬇️

scientific article published on February 15, 1979

Development of an affinity ligand for purification of .alpha.2-adrenoceptors from human platelet membranes ⬇️

scientific article published on July 1, 1984

Different sedimentation properties of agonist- and antagonist-labelled platelet alpha2 adrenergic receptors ⬇️

scientific article published on June 16, 1981

Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors

scientific article

Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.

scientific article published on December 2002

Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice

scientific article published in January 2003

Differential quantal release of histamine and 5-hydroxytryptamine from mast cells of vesicular monoamine transporter 2 knockout mice

scientific article published on January 2000

Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases

scientific article published on February 1996

Differential regulation of the dopamine D1, D2 and D3 receptor gene expression and changes in the phenotype of the striatal neurons in mice lacking the dopamine transporter

scientific article published in January 2000

Differential regulation of the dopamine D2 and D3 receptors by G protein-coupled receptor kinases and beta-arrestins

scientific article published on 25 July 2001

Differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter.

scientific article published on October 1999

Direct Demonstration of Impaired Functionality of a Purified Desensitized β-Adrenergic Receptor in a Reconstituted System ⬇️

scientific article published on August 24, 1984

Direct radioligand measurement of dopamine receptors in the anterior pituitary gland

scientific article published in January 1983

Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor.

scientific article

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.

scientific article

Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators

scientific article published on 20 August 2019

Discovery of β-Arrestin–Biased Dopamine D 2 Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy ⬇️

scientific article published on October 24, 2011

Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis ⬇️

scientific article published on January 25, 1992

Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4

scientific article (publication date: 5 September 2003)

Dissecting the contribution of individual receptor subunits to the enhancement of N-methyl-d-aspartate currents by dopamine D1 receptor activation in striatum

scientific article published on 11 May 2011

Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties.

scientific article published on December 2016

Distribution of alpha 2-adrenergic receptor subtype gene expression in rat brain

scientific article published on January 1994

Dopamine D(5) receptor immunolocalization in rat and monkey brain

scientific article published on 01 August 2000

Dopamine D2 receptor relies upon PPM/PP2C protein phosphatases to dephosphorylate huntingtin protein

scientific article published on 11 March 2014

Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors

scientific journal article

Dopamine enhances motor and neuropathological consequences of polyglutamine expanded huntingtin

scientific article

Dopamine levels modulate the updating of tastant values

scientific article published on 17 July 2006

Dopamine neuronal transport kinetics and effects of amphetamine

scientific article published in December 1999

Dopamine receptor of the porcine anterior pituitary gland. Effects of N-ethylmaleimide and heat on ligand binding mimic the effects of guanine nucleotides.

scientific article published in September 1982

Dopamine receptor of the porcine anterior pituitary gland. Evidence for two affinity states discriminated by both agonists and antagonists

scientific article published in September 1982

Dopamine receptor of the porcine anterior pituitary gland. Solubilization and characterization

scientific article published in June 1984

Dopamine receptor subtypes: beyond the D1/D2 classification

scientific article published on June 1990

Dopamine receptors and brain function.

scientific article published on January 1996

Dopamine receptors: from structure to function

scientific article

Dopamine tone regulates D1 receptor trafficking and delivery in striatal neurons in dopamine transporter-deficient mice.

scientific article published on February 2000

Dopamine transporter and vesicular monoamine transporter knockout mice : implications for Parkinson's disease

scientific article

Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium.

scientific article published on October 1993

Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter.

scientific article published in September 1997

Dopamine transporter-dependent and -independent actions of trace amine beta-phenylethylamine.

scientific article published in October 2004

Dopamine transporters and neuronal injury

scientific article

Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease

scientific article

Dopamine: from pharmacology to molecular biology and back

scientific article published in October 2006

Dopaminergic control of sleep-wake states.

scientific article

Dopaminergic inhibition of adenylate cyclase correlates with high affinity agonist binding to anterior pituitary D2 dopamine receptors

scientific article published in July 1984

Dopaminergic receptors in the anterior pituitary gland. Correlation of [3H]dihydroergocryptine binding with the dopaminergic control of prolactin release ⬇️

scientific article published on April 10, 1978

Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice

scientific article (publication date: 24 April 2003)

Dual Control of Dopamine Synthesis and Release by Presynaptic and Postsynaptic Dopamine D2 Receptors ⬇️

scientific article published on June 27, 2012

Dual couplings of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein ⬇️

scientific article published on 01 January 1991

Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization

scientific article published on August 1996

Dysautonomia due to reduced cholinergic neurotransmission causes cardiac remodeling and heart failure

scientific article

Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder

scientific article

Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated DeltaE-torsinA mutant

scientific article

Effector coupling mechanisms of the cloned 5-HT1A receptor

scientific article

Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression

scientific article published on 07 May 2019

Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-Like Behavior in Hypoglutamatergic Mice

scientific article

Elimination of GRK2 from Cholinergic Neurons Reduces Behavioral Sensitivity to Muscarinic Receptor Activation ⬇️

scientific article published on August 15, 2012

Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission

scientific article

Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor

scientific article published on 11 May 2015

Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs

scientific article published on 03 June 2019

Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins

scientific article

Engineered D2R Variants Reveal the Balanced and Biased Contributions of G-Protein and β-Arrestin to Dopamine-Dependent Functions.

scientific article published on 25 October 2017

Enhanced morphine analgesia in mice lacking beta-arrestin 2

scientific journal article

Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice.

scientific article published in November 2003

Epidermal growth factor promotes uncoupling from adenylyl cyclase of the rat D2S receptor expressed in GH4C1 cells.

scientific article published on March 1994

Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase.

scientific article published in January 1998

Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function

scientific journal article

Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2

scientific article

Experimental genetic approaches to addiction.

scientific article

Expression of a human cDNA encoding the beta 2-adrenergic receptor in Chinese hamster fibroblasts (CHW): functionality and regulation of the expressed receptors.

scientific article

Expression of mRNA coding for the serotonin transporter in aged vs. young rat brain: differential effects of glucocorticoids

scientific article published on 01 May 1996

Expression of three alpha 2-adrenergic receptor subtypes in rat tissues: implications for alpha 2 receptor classification

scientific article published on November 1990

Following the trace of elusive amines

scientific article

Food for thought: the physiological relevance of ghrelin and dopamine D2 receptor heterodimerization in the regulation of appetite

scientific article published in January 2012

Food reward in the absence of taste receptor signaling

scientific article

From ligand binding to gene expression: new insights into the regulation of G-protein-coupled receptors ⬇️

scientific article published on January 1, 1992

Functional activity and regulation of human beta 2-adrenergic receptors expressed in Xenopus oocytes.

scientific article

Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein)

scientific article

Functional differences in the beta gamma complexes of transducin and the inhibitory guanine nucleotide regulatory protein

scientific article published on 01 March 1987

Functional hyperdopaminergia in dopamine transporter knock-out mice

scientific article

Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1

scientific article

Functional interaction between trace amine-associated receptor 1 and dopamine D2 receptor

scientific article

Functional interactions of recombinant alpha 2 adrenergic receptor subtypes and G proteins in reconstituted phospholipid vesicles

scientific article

Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2.

scientific article published in January 2006

G Protein and β-arrestin signaling bias at the ghrelin receptor

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G Protein-coupled Receptor Kinase 3 (GRK3) Gene Disruption Leads to Loss of Odorant Receptor Desensitization ⬇️

scientific article published on October 10, 1997

G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.

scientific article published on 02 October 2009

G protein-coupled receptor adaptation mechanisms ⬇️

scientific article published on 01 April 1998

G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation.

scientific article published on 17 October 2003

G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation.

scientific article published on February 2005

G protein-coupled receptor kinase/beta-arrestin systems and drugs of abuse: psychostimulant and opiate studies in knockout mice.

scientific article published on January 2004

G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal

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G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity ⬇️

scientific article published on December 15, 1991

G-protein-coupled receptor kinases and arrestins: regulators of G-protein-coupled receptor sequestration

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G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins

scientific article published on October 1996

G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins

scientific article published on January 1, 1992

GRK2: multiple roles beyond G protein-coupled receptor desensitization ⬇️

scientific article published on January 23, 2012

Gene-dose dependent effects of methamphetamine on interval timing in dopamine-transporter knockout mice

scientific article published on 4 February 2011

Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine

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Genetic and genomic approaches to reward and addiction

scientific article published in January 2004

Genetic animal models: focus on schizophrenia

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Genetic approaches to studying norepinephrine function: knockout of the mouse norepinephrine transporter gene

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Genetic mapping of the ?-arrestin 1 and 2 genes on mouse Chromosomes 7 and 11 respectively

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Genetic models in pharmacology: present status and future

scientific article published on 01 June 1999

Genetic regulation of beta-adrenergic receptors

scientific article

Genetics of childhood disorders: XXIV. ADHD, part 8: hyperdopaminergic mice as an animal model of ADHD.

scientific article

Genomic organization of adrenergic and serotonin receptors in the mouse: Linkage mapping of sequence-related genes provides a method for examining mammalian chromosome evolution ⬇️

scientific article published on June 1, 1991

Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2.

scientific article

Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter

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Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion.

scientific article published in June 1994

Green Fluorescent Protein-Tagged β-Arrestin Translocation as a Measure of G Protein-Coupled Receptor Activation

scientific article published on January 1, 2004

Grk5l controls heart development by limiting mTOR signaling during symmetry breaking.

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Growth Arrest Specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling

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Guanine nucleotides and alpha1 adrenergic receptors in the heart ⬇️

scientific article published on 01 January 1983

Guanine nucleotides regulate both dopaminergic agonist and antagonist binding in porcine anterior pituitary

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Hedgehog signaling: is Smo a G protein-coupled receptor?

scientific article published on February 2009

Hepatic β-arrestin 2 is essential for maintaining euglycemia

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Heterogeneity of dopamine receptors.

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High affinity agonist binding to the dopamine D3 receptor: chimeric receptors delineate a role for intracellular domains

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High agonist-independent activity is a distinguishing feature of the dopamine D1B receptor subtype

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Homologous desensitization of adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor

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Homologous desensitization of the beta-adrenergic receptor. Functional integrity of the desensitized receptor from mammalian lung

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Human Dopamine Transporter Gene Not Linked to Schizophrenia in Multigenerational Pedigrees

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Human beta 1- and beta 2-adrenergic receptors: structurally and functionally related receptors derived from distinct genes

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Human serotonin1B receptor expression in Sf9 cells: phosphorylation, palmitoylation, and adenylyl cyclase inhibition

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Human β1- and β2-adrenergic receptors: structurally and functionally related receptors derived from distinct genes

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Hyperactivity and impaired response habituation in hyperdopaminergic mice

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Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice

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Hyperdopaminergia and NMDA receptor hypofunction disrupt neural phase signaling

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Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

scientific article

Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2

scientific journal article

Identification and sequence of a binding site peptide of the beta 2-adrenergic receptor

scientific article published on March 1988

Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions

scientific article published on 10 October 2003

Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity

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Identification of adenylate cyclase-coupled beta-adrenergic receptors in frog erythrocytes with (minus)-[3-H] alprenolol ⬇️

scientific article published on July 10, 1975

Identification of the D2-dopamine receptor binding subunit in several mammalian tissues and species by photoaffinity labeling

scientific article published in July 1986

Identification of the GPR55 agonist binding site using a novel set of high-potency GPR55 selective ligands

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Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands.

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Identification of the binding subunit of the D1-dopamine receptor by photoaffinity crosslinking

scientific article published on 01 February 1987

Identification of the ligand-binding subunit of the human 5-hydroxytryptamine1A receptor with N-(p-azido-m-[125I] iodophenethyl)spiperone, a high affinity radioiodinated photoaffinity probe

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Identification of the subunit structure of rat pineal adrenergic receptors by photoaffinity labeling

scientific article published on April 1986

Identification of the subunit-binding site of alpha 2-adrenergic receptors using [3H]phenoxybenzamine ⬇️

scientific article published on June 25, 1984

Identification, Quantification, and Localization of mRNA for Three Distinct Alpha1Adrenergic Receptor Subtypes in Human Prostate ⬇️

scientific article published on 01 August 1993

Identification, characterization, and molecular cloning of a novel transporter-like protein localized to the central nervous system

scientific article published on November 9, 1992

Imidazole-derived agonists for the neurotensin 1 receptor.

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Immunoaffinity purification of epitope-tagged human beta 2-adrenergic receptor to homogeneity

scientific article published on December 1995

Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner.

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Impaired formation of beta-adrenergic receptor-nucleotide regulatory protein complexes in pseudohypoparathyroidism.

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Implanted reuptake-deficient or wild-type dopaminergic neurons improve ON L-dopa dyskinesias without OFF-dyskinesias in a rat model of Parkinson's disease.

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Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice.

scientific article published in May 1998

Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter

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Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.

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Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice.

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Increased rewarding properties of morphine in dopamine-transporter knockout mice

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Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled receptor-5 diminishes cell fitness.

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Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors

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Inhibition of the beta-adrenergic receptor kinase by polyanions.

scientific article published in April 1989

Inhibition of the dopamine D1 receptor signaling by PSD-95.

scientific article published on 16 March 2007

Integrated approaches to understanding antipsychotic drug action at GPCRs

scientific article published on 14 December 2013

Internal trafficking and surface mobility of a functionally intact beta2-adrenergic receptor-green fluorescent protein conjugate

scientific article published on 01 February 1997

International Workshop at the Nobel Forum, Karolinska Institutet on G protein-coupled receptors: finding the words to describe monomers, oligomers, and their molecular mechanisms and defining their meaning. Can a consensus be reached?

scientific article published in October 2010

Intranigral administration of D2 dopamine receptor antisense oligodeoxynucleotides establishes a role for nigrostriatal D2 autoreceptors in the motor actions of cocaine

scientific article published on July 1994

Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptor

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Isolation and characterization of the beta-adrenergic receptor of frog erythrocytes and development of potential affinity ligands

scientific article published on 01 January 1981

Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases

scientific article published on September 10, 1992

Isoprenylation of a protein kinase. Requirement of farnesylation/alpha-carboxyl methylation for full enzymatic activity of rhodopsin kinase

scientific article published on January 1992

Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine.

scientific article published in December 1997

Lgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions

Lgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions.

scientific article

Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase

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Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

scholarly article

Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals

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Localization of D1 dopamine receptor mRNA in brain supports a role in cognitive, affective, and neuroendocrine aspects of dopaminergic neurotransmission

scientific article published on May 1991

Localization of mRNA for three distinct alpha 1-adrenergic receptor subtypes in human tissues: implications for human alpha-adrenergic physiology

scientific article published in February 1994

Localization of the cDNA for an alpha 1-adrenergic receptor subtype (ADRA1D) to chromosome band 20p13.

scientific article

Localization of the fourth membrane spanning domain as a ligand binding site in the human platelet alpha 2-adrenergic receptor

scientific article published on 01 May 1989

Location and molecular cloning of D1 dopamine receptor

scientific article published on March 1, 1992

Looking at lithium: molecular moods and complex behaviour

scientific article published on October 2008

Loss of autoreceptor functions in mice lacking the dopamine transporter

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Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression

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MDMA "ecstasy" alters hyperactive and perseverative behaviors in dopamine transporter knockout mice

scientific article published on 28 January 2004

ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse

scientific article published on 27 April 2016

Macromolecular beta-adrenergic antagonists discriminating between receptor and antibody ⬇️

scientific article published on April 1, 1980

Magnetic resonance imaging at microscopic resolution reveals subtle morphological changes in a mouse model of dopaminergic hyperfunction.

scientific article published on May 2005

Mammalian .beta.2-adrenergic receptor: purification and characterization ⬇️

scientific article published on September 25, 1984

Mammalian alpha 1-adrenergic receptor. Purification and characterization of the native receptor ligand binding subunit

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Mammalian beta-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains ⬇️

scientific article published on July 10, 1984

Mammalian beta-adrenergic receptors. Structural differences in beta 1 and beta 2 subtypes revealed by peptide maps

scientific article published on September 1983

Mechanism of Action of Hypothalamic Hormones in the Anterior Pituitary Gland and Specific Modulation of Their Activity by Sex Steroids and Thyroid Hormones

scientific article published on January 1, 1978

Mechanism of guanine nucleotide regulatory protein-mediated inhibition of adenylate cyclase. Studies with isolated subunits of transducin in a reconstituted system.

scientific article published in July 1986

Mechanisms involved in adrenergic receptor desensitization.

scientific article published on August 1990

Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter

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Mechanisms of hormone receptor-effector coupling: the beta-adrenergic receptor and adenylate cyclase

scientific article published on 01 August 1982

Mechanisms of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors

scientific article published on June 1984

Mechanisms of neuroprotection against ischemic insult by stress-inducible phosphoprotein-1/prion protein complex.

scientific article published on 18 December 2017

Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration

scientific article published on April 1996

Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression

scientific article

Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition

scientific article published in September 2006

Mice lacking the dopamine transporter display altered regulation of distal colonic motility

scientific article published on 01 August 2000

Mice lacking the norepinephrine transporter are supersensitive to psychostimulants

scientific article

Mice with reduced NMDA receptor expression display behaviors related to schizophrenia

scientific journal article

MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction

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Model systems for the study of seven-transmembrane-segment receptors ⬇️

scientific article published on January 1, 1991

Modeling of sequestration and down regulation in cells containing beta2-adrenergic receptors

scientific article published in January 1995

Molecular Biology of Adrenergic Receptors

scientific article published on 01 January 1988

Molecular Characterization of G-protein Coupled Receptors: Isolation and Cloning of a D1 Dopamine Receptor ⬇️

scientific article published on January 1, 1991

Molecular and regulatory properties of adrenergic receptors

scientific article published on January 1987

Molecular biology of adrenergic receptors in the rat and frog central nervous system ⬇️

scientific article published on September 1, 1984

Molecular biology of alpha-adrenergic receptors: implications for receptor classification and for structure-function relationships

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Molecular biology, pharmacology and functional role of the plasma membrane dopamine transporter

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Molecular characterization of dopamine receptors

scientific article published on June 1990

Molecular characterization of the dopamine transporter.

scientific article

Molecular characterization of the β-adrenergic receptor of frog erythrocytes ⬇️

scientific article published on July 1, 1982

Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype

scientific article

Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5 ⬇️

scientific article published on April 5, 1991

Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor

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Molecular cloning and expression of the gene for a human D1 dopamine receptor

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Molecular cloning, stable expression and desensitization of the human dopamine D1b/D5 receptor

scientific article published on January 1993

Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*

scientific article (publication date: June 2001)

Molecular mechanisms of G protein-coupled receptor desensitization and resensitization ⬇️

scientific article published on 01 January 1998

Molecular mechanisms of G protein-coupled receptor signaling: role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization

scientific article published on January 1, 1997

Molecular mechanisms of beta-adrenergic receptor desensitization

scientific article published in January 1987

Monoamine transporter pharmacology and mutant mice

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Monoamine transporters: from genes to behavior

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Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence

scientific journal article

Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors

scientific article published on February 1990

Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells

scientific article

Multiscale imaging characterization of dopamine transporter knockout mice reveals regional alterations in spine density of medium spiny neurons

scientific article

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

scientific article published on 01 December 1999

Mutagenesis of the beta2-Adrenergic Receptor: How Structure Elucidates Function ⬇️

scientific article published on January 1, 1992

Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2

scientific article (publication date: 7 April 2000)

Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration ⬇️

scientific article published on February 1, 1991

N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement.

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N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity

scientific article published on 5 December 2007

N-terminal tyrosine modulation of the endocytic adaptor function of the beta-arrestins.

scientific article published on 24 April 2007

Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance

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New Concepts in Dopamine D2 Receptor Biased Signaling and Implications for Schizophrenia Therapy

scientific article published on 19 October 2016

No association between alleles or genotypes at the dopamine transporter gene and schizophrenia

scientific article published on 01 April 1994

Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony

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Norepinephrine transporter-deficient mice respond to anxiety producing and fearful environments with bradycardia and hypotension.

scientific article published on 3 March 2006

Norepinephrine-induced down regulation of alpha1 adrenergic receptors in cultured rabbit aorta smooth muscle cells ⬇️

scientific article published on 01 October 1983

Novel adamantyl cannabinoids as CB1 receptor probes

scientific article published on 14 May 2013

Novel roles for β-arrestins in the regulation of pharmacological sequestration to predict agonist-induced desensitization of dopamine D3 receptors

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Novel strains of mice deficient for the vesicular acetylcholine transporter: insights on transcriptional regulation and control of locomotor behavior

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Novelty seeking and stereotypic activation of behavior in mice with disruption of the Dat1 gene

scientific article published in October 2005

Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter

scientific article published on 11 November 2002

Ontogeny of D1A and D2 dopamine receptor subtypes in rat brain using in situ hybridization and receptor binding

scientific article published on 01 September 1994

Ontogeny of the striatal neurons expressing the D1 dopamine receptor in humans

scientific article published in June 1996

Opposite function of dopamine D1 and N‐methyl‐D‐aspartate receptors in striatal cannabinoid‐mediated signaling ⬇️

scientific article published on November 1, 2011

Optimizing the Temporal Resolution of Fast-Scan Cyclic Voltammetry ⬇️

scientific article published on January 30, 2012

Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors

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Overexpression of pp60c-src is associated with altered regulation of adenylyl cyclase

scientific article published on September 1992

Overlapping and opposing functions of G protein-coupled receptor kinase 2 (GRK2) and GRK5 during heart development

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PM435. Targeting Functional Selectivity of the Dopamine D2 Receptor for Treatment of Schizophrenia-like Behaviors.

scientific article published on 27 May 2016

PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors

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Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor

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Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults.

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Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice

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Persistent hyperdopaminergia decreases the peak frequency of hippocampal theta oscillations during quiet waking and REM sleep

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Pharmacological blockade of a β2AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model ⬇️

scientific article published on January 15, 2012

Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning ⬇️

scientific article published on July 1, 1992

Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor

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Phenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2.

scientific article

Phorbol ester effects on alpha 1-adrenoceptor binding and phosphatidylinositol metabolism in cultured vascular smooth muscle cells

scientific article published on 01 December 1985

Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism

scientific article published on September 1985

Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex

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Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase

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Phosphorylation and palmitoylation of the human D2L dopamine receptor in Sf9 cells

scientific article published on November 1994

Phosphorylation of cell surface receptors: a mechanism for regulating signal transduction pathways

scientific article published on February 1988

Phosphorylation of chick heart muscarinic cholinergic receptors by the beta-adrenergic receptor kinase

scientific article published on 01 May 1989

Phosphorylation of the beta-adrenergic receptor accompanies catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase

scientific article published on January 1983

Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulator

scientific article published on 01 June 1985

Phosphorylation sites on two domains of the beta 2-adrenergic receptor are involved in distinct pathways of receptor desensitization.

scientific article

Photoaffinity cross-linking of a radioiodinated probe, 125I-A55453, into alpha 1-adrenergic receptors ⬇️

scientific article published on September 1, 1984

Photoaffinity labeling of mammalian alpha 1-adrenergic receptors. Identification of the ligand binding subunit with a high affinity radioiodinated probe ⬇️

scientific article published on February 25, 1984

Photoaffinity labeling of the D2-dopamine receptor using a novel high affinity radioiodinated probe

scientific article published in February 1985

Photoaffinity labeling of the beta-adrenergic receptor ⬇️

scientific article published on November 25, 1981

Photoaffinity labeling of turkey erythrocyte beta-adrenergic receptors: Degradation of the Mr = 49,000 protein explains apparent heterogeneity ⬇️

scientific article published on March 15, 1984

Photoaffinity labeling of β-adrenergic receptors in mammalian tissues ⬇️

scientific article published on December 1, 1984

Photoaffinity labelling of mammalian beta-adrenergic receptors: Metal-dependent proteolysis explains apparent heterogeneity ⬇️

scientific article published on January 27, 1983

Plasma membrane transporters of serotonin, dopamine, and norepinephrine mediate serotonin accumulation in atypical locations in the developing brain of monoamine oxidase A knock-outs.

scientific article published in September 1998

Potent beta-adrenergic antagonist possessing chemically reactive group

scientific article published on November 1980

Potentiated opioid analgesia in norepinephrine transporter knock-out mice.

scientific article

Pregnenolone Rescues Schizophrenia-Like Behavior in Dopamine Transporter Knockout Mice ⬇️

scientific article published on December 11, 2012

Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists

scientific journal article

Probing the Allosteric Role of the α5 Subunit of α3β4α5 Nicotinic Acetylcholine Receptors by Functionally Selective Modulators and Ligands

scientific article

Production of adrenergic receptors in yeast

scientific article published on 01 January 1996

Profound neuronal plasticity in response to inactivation of the dopamine transporter

scientific journal article

Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance

scientific article

Properties of secretin receptor internalization differ from those of the beta(2)-adrenergic receptor

scientific article published on 01 October 1999

Properties of the beta 1- and beta 2-adrenergic receptor subtypes revealed by molecular cloning

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Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin.

scientific article

Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase ⬇️

scientific article published on December 8, 1983

Purification and characterization of the D2-dopamine receptor from bovine anterior pituitary.

scientific article published in December 1988

Purification and characterization of the beta-adrenergic receptor kinase

scientific article

Purification and characterization of the human platelet alpha 2-adrenergic receptor.

scientific article

Purification of the beta-adrenergic receptor. Identification of the hormone binding subunit ⬇️

scientific article published on June 10, 1981

Quantitative Label-Free Phosphoproteomics Strategy for Multifaceted Experimental Designs ⬇️

scientific article published on April 22, 2011

RNA Editing Induces Variation in Desensitization and Trafficking of 5-Hydroxytryptamine 2c Receptor Isoforms ⬇️

scientific article (publication date: 23 January 2004)

Rab5 Association with the Angiotensin II Type 1A Receptor Promotes Rab5 GTP Binding and Vesicular Fusion ⬇️

scientific article published on October 26, 2001

Rapid alterations in corticostriatal ensemble coordination during acute dopamine-dependent motor dysfunction

scientific article

Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis

scientific article published on 01 May 1998

Real-time visualization of the cellular redistribution of G protein-coupled receptor kinase 2 and beta-arrestin 2 during homologous desensitization of the substance P receptor

scientific article published on March 1999

Recent advances in the molecular biology of dopamine receptors

scientific article

Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity

scientific article published on 30 October 2015

Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems ⬇️

scientific article published on April 25, 1992

Reconstitution of a hormone-sensitive adenylate cyclase system. The pure beta-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit ⬇️

scientific article published on August 25, 1984

Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system ⬇️

scientific article published on August 1, 1983

Reconstitution of the beta-adrenergic receptor

scientific article published on January 1985

Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter.

scientific article published on 30 September 2008

Reduced expression of the vesicular acetylcholine transporter causes learning deficits in mice.

scientific article

Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function

scientific article

Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo

scientific journal article

Regulation of G protein-coupled receptors by agonist-dependent phosphorylation

scientific article published on January 1990

Regulation of adenylate cyclase coupled beta-adrenergic receptors

scientific article published on January 1976

Regulation of adenylate cyclase coupled beta-adrenergic receptors by beta-adrenergic catecholamines

scientific article published on August 1, 1976

Regulation of adenylyl cyclase-coupled beta-adrenergic receptors

scientific article published on January 1988

Regulation of adrenergic receptor function by phosphorylation

scientific article published on January 1986

Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells

scientific article

Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase

scientific article published in Journal of Biological Chemistry

Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression

scientific article published on January 1991

Regulation of arrestin-3 phosphorylation by casein kinase II

scientific article (publication date: 10 May 2002)

Regulation of beta-adrenergic receptors by guanyl-5'-yl imidodiphosphate and other purine nucleotides ⬇️

scientific article published on August 10, 1976

Regulation of hormone receptors and adenylyl cyclases by guanine nucleotide binding N proteins

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Regulation of responsiveness at D2 dopamine receptors by receptor desensitization and adenylyl cyclase sensitization

scientific article published on January 1991

Regulation of the beta 2-adrenergic receptor and its mRNA in the rat ventral prostate by testosterone

scientific article published on 01 June 1988

Regulation of transmembrane signaling by receptor phosphorylation

scientific article published on March 1987

Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery

scientific article

Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization

scientific article published in Nature

Reply to Belmaker : GSK3β haploinsufficiency results in lithium-like effects in the forced-swim test

scholarly article

Reply: receptor specificity of G-protein-coupled receptor kinases

scientific article published on 01 October 2000

Rod vision is controlled by dopamine-dependent sensitization of rod bipolar cells by GABA.

scientific article published on October 2011

Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness

scientific article published on June 1998

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency

scholarly article

Role of acidic amino acids in peptide substrates of the .beta.-adrenergic receptor kinase and rhodopsin kinase ⬇️

scientific article published on May 28, 1991

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors

scientific article published on August 28, 1992

Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization

scientific article published on January 1996

Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter.

scientific article published on July 1998

Role of extracellular disulfide-bonded cysteines in the ligand binding function of the beta 2-adrenergic receptor

scientific article published on March 1990

Role of phosphorylation in agonist-promoted beta 2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by beta ARK1

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Role of phosphorylation in desensitization of the beta-adrenoceptor

scientific article published on May 1990

Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity

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Role of the beta-adrenergic receptor kinase in desensitization of the alpha 2-adrenergic receptor

scientific article published on January 1, 1991

Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility

scientific article

Role of β-Arrestins in the IntracelIular Trafficking of G-Protein-Coupled Receptors

scientific article published on January 1, 1998

Roles of protein kinase C and actin-binding protein 280 in the regulation of intracellular trafficking of dopamine D3 receptor

scientific article

SSRI Augmentation by 5-Hydroxytryptophan Slow Release: Mouse Pharmacodynamic Proof of Concept

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Screening for Selective Ligands for GPR55 - Antagonists ⬇️

scientific article published on November 18, 2011

Selective GPR35 Antagonists - Probe 3

scientific article published on 27 July 2012

Selective GPR35 Antagonists - Probes 1 & 2 ⬇️

scientific article published on March 25, 2011

Selective Inhibition of Adenylyl Cyclase Type V by the Dopamine D3Receptor ⬇️

scientific article published on 01 September 1997

Selective KOP Receptor Agonists: Probe 1 & Probe 2 ⬇️

scientific article published on March 25, 2011

Selective KOP Receptor Antagonists: Probe 1 ⬇️

scientific article published on March 25, 2011

Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmission

scientific article

Separation of solubilized alpha and beta adrenergic receptors by affinity chromatography ⬇️

scientific article published on May 14, 1979

Serotonin deficiency alters susceptibility to the long-term consequences of adverse early life experience

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Sex differences in response to chronic mild stress and congenital serotonin deficiency

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Signal transduction. Bringing channels closer to the action!

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Signaling, desensitization, and trafficking of G protein-coupled receptors revealed by green fluorescent protein conjugates

scientific article published on 01 January 1999

Silencing of the constitutive activity of the dopamine D1B receptor. Reciprocal mutations between D1 receptor subtypes delineate residues underlying activation properties

scientific article published on 01 November 1996

Site-directed mutagenesis of the cytoplasmic domains of the human beta 2-adrenergic receptor. Localization of regions involved in G protein-receptor coupling

scientific article

Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism ⬇️

scientific article published on March 5, 1992

Skeletal muscle beta-adrenergic receptors: variations due to fiber type and training ⬇️

scientific article published on February 1, 1984

Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept

scientific article published on 29 April 2019

Small Molecule Agonists for the Neurotensin 1 Receptor (NTR1 Agonists)

Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2

scientific article

Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase

scientific article published on 24 September 2008

Solubilization and characterization of D2-dopamine receptors in an estrone-induced, prolactin-secreting rat pituitary adenoma

scientific article published on 01 November 1986

Solubilization and characterization of the beta-adrenergic receptor binding sites of frog erythrocytes ⬇️

scientific article published on April 25, 1976

Solubilization of rat liver alpha 1-adrenergic receptors. Agonist specific alteration in receptor binding affinity

scientific article published on 01 November 1983

Somatostatin induces translocation of the beta-adrenergic receptor kinase and desensitizes somatostatin receptors in S49 lymphoma cells

scientific article published on 01 May 1987

Specificity of receptor-G protein interactions. Discrimination of Gi subtypes by the D2 dopamine receptor in a reconstituted system.

scientific article published in March 1990

Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles

scientific article published on 01 February 1985

Spinal cord stimulation restores locomotion in animal models of Parkinson's disease

scientific article

Stereospecific (3H)(minus)-alprenolol binding sites, beta-adrenergic receptors and adenylate cyclase

scientific article published in September 1974

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs

scientific article

Structural basis of beta-adrenergic receptor subtype specificity studied with chimeric beta 1/beta 2-adrenergic receptors

scientific article

Structure and Function of the Adrenergic Receptor Family ⬇️

scientific article published on January 1, 1991

Structure and Regulation of G Protein-Coupled Receptors: The β2-Adrenergic Receptor as a Model

scientific article published on January 1, 1991

Structure and function of beta-adrenergic receptors: regulation at the molecular level

scientific article published on January 1, 1984

Structure and function of the beta 2-adrenergic receptor--homology with rhodopsin

scientific article published on December 1987

Structure of the adrenergic and related receptors

scientific article

Structure-activity relationships of adenylate cyclase-coupled beta adrenergic receptors: determination by direct binding studies ⬇️

scientific article published on January 1, 1976

Substitution of an extracellular cysteine in the beta 2-adrenergic receptor enhances agonist-promoted phosphorylation and receptor desensitization

scientific article

Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons.

scientific article

Synergistic regulation of beta2-adrenergic receptor sequestration: intracellular complement of beta-adrenergic receptor kinase and beta-arrestin determine kinetics of internalization

scientific article published on May 1997

Synthesis of iodine-125 labeled (.+-.)-15-[4-azidobenzyl]carazolol: a potent .beta.-adrenergic photoaffinity probe ⬇️

scientific article published on June 1, 1983

Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase

scientific article published on January 1990

TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity

scientific article

Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity

scientific article

Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's disease

scientific article

Temperature immutability of adenyl cyclase-coupled β adrenergic recptors

scientific article published in Nature

The Akt-GSK-3 signaling cascade in the actions of dopamine

scientific article published on 8 March 2007

The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein

scientific article published on 01 April 1987

The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin

scientific article published on May 1998

The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain ⬇️

scientific article published on October 1, 1992

The Human Placenta—A Rich Source of β-Adrenergic Receptors: Characterization of the Receptors in Particulate and Solubilized Preparations* ⬇️

scientific article published on 01 June 1980

The NH2-terminus of Norepinephrine Transporter Contains a Basolateral Localization Signal for Epithelial Cells ⬇️

scientific article published on December 1, 2001

The Role of Arrestins in Development

scientific article published on January 1, 2013

The adrenergic receptors

scientific article published on January 1990

The alpha 1C-adrenergic receptor: a new member in the alpha 1-adrenergic receptor family.

scientific article published on January 1990

The alpha 1C-adrenergic receptor: characterization of signal transduction pathways and mammalian tissue heterogeneity ⬇️

scientific article published on November 1, 1991

The beta 1-adrenergic receptor of the turkey erythrocyte. Molecular heterogeneity revealed by purification and photoaffinity labeling ⬇️

scientific article published on October 25, 1982

The beta-adrenergic receptor and adenylate cyclase

scientific article published on April 13, 1976

The beta-adrenergic receptor kinase: role in homologous desensitization in S49 lymphoma cells.

scientific article published in January 1988

The beta-adrenergic receptor: rapid purification and covalent labeling by photoaffinity crosslinking ⬇️

scientific article published on May 1, 1982

The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis

scientific article

The cardiac beta-adrenergic receptor. Structural similarities of beta 1 and beta 2 receptor subtypes demonstrated by photoaffinity labeling ⬇️

scientific article published on July 10, 1983

The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the beta 2-adrenergic receptor

scientific article published on 01 November 1995

The dopamine D2 receptor can directly recruit and activate GRK2 without G protein activation.

scientific article published on 27 February 2018

The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice

scientific journal article

The dopamine metabolite 3-methoxytyramine is a neuromodulator

scientific article published in 2010

The dopamine transporter. The cloned target site of parkinsonism-inducing toxins and of drugs of abuse

scientific article published on January 1996

The dopamine transporter: a crucial component regulating dopamine transmission.

scientific article published on September 1997

The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress ⬇️

scientific article published on May 14, 2013

The effects of congenital brain serotonin deficiency on responses to chronic fluoxetine ⬇️

scientific article published on August 13, 2013

The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor

scientific journal article

The human 5-HT1A receptor expressed in HeLa cells stimulates sodium-dependent phosphate uptake via protein kinase C

scientific article published on 01 December 1989

The interaction of beta-arrestin with the AP-2 adaptor is required for the clustering of beta 2-adrenergic receptor into clathrin-coated pits

scientific article (publication date: 28 July 2000)

The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse

scientific article

The mammalian beta 2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system

scientific article published in September 1984

The mammalian beta-adrenergic receptor: structural and functional characterization of the carbohydrate moiety

scientific article published on 01 January 1987

The mammalian beta-adrenergic receptors.

scientific article published on January 1989

The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter

scientific article

The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis

scientific article published in Journal of Biological Chemistry

The new biology of drug receptors

scientific article

The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase ⬇️

scientific article published on October 1, 1991

The role of GRK6 in animal models of Parkinson's disease and L-DOPA treatment

scientific article

The selective serotonin-2A receptor antagonist M100907 reverses behavioral deficits in dopamine transporter knockout mice.

scientific article published in February 2004

The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation

scientific article published on 6 December 2002

The stem cell-expressed receptor Lgr5 possesses canonical and functionally active molecular determinants critical to β-arrestin-2 recruitment

scientific article

The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2 ⬇️

scientific article published on May 5, 1993

The vesicular acetylcholine transporter is required for neuromuscular development and function

scientific article

Trace amine associated receptor 1 and movement control

scientific article published on 27 June 2008

Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics.

scientific article

Trace amine-associated receptors as emerging therapeutic targets

scientific article

Trafficking of the vesicular acetylcholine transporter in SN56 cells: a dynamin-sensitive step and interaction with the AP-2 adaptor complex

scientific article published on September 2002

Transducin and the inhibitory nucleotide regulatory protein inhibit the stimulatory nucleotide regulatory protein mediated stimulation of adenylate cyclase in phospholipid vesicle systems

scientific article published in August 1985

Triphenylmethane dye activation of beta-arrestin

scientific article published on August 2013

Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice

scientific article

Tryptophan hydroxylase-2 controls brain serotonin synthesis

scientific article

Turning off the signal: desensitization of beta-adrenergic receptor function

scientific article published on August 1990

Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level

scientific article published in October 1989

Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor

Tyrosine phosphorylation of G protein alpha subunits by pp60c-src ⬇️

scientific article published on July 1, 1992

VNTR polymorphism for the human dopamine transporter gene (DAT1)

scientific article published on 01 March 1993

Visualization of Dynamic Trafficking of a Protein Kinase C βII/Green Fluorescent Protein Conjugate Reveals Differences in G Protein-coupled Receptor Activation and Desensitization ⬇️

scientific article published on April 24, 1998

Vmat2 heterozygous mutant mice display a depressive-like phenotype.

scientific article

Withdrawal from continuous or intermittent cocaine administration: changes in D2 receptor function.

scientific article published in May 1994

beta-Adrenergic receptor kinase. Activity of partial agonists for stimulation of adenylate cyclase correlates with ability to promote receptor phosphorylation

scientific article published on 01 March 1988

beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin

scientific article (publication date: 15 March 2002)

beta-Arrestin: a protein that regulates beta-adrenergic receptor function

scientific article

cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure

scientific article

cDNA cloning and chromosomal localization of the human beta-adrenergic receptor kinase.

scientific article

cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor

scientific article

β-Adrenergic receptors: Solubilization of (−)[3H]alprenolol binding sites from frog erythrocyte membranes ⬇️

scientific article published on January 26, 1976

β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors

scientific article published on 26 May 2020

β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions

scientific article published on February 2017

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