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List of works by Howard E. Gendelman

4-Aminopyridine improves spatial memory in a murine model of HIV-1 encephalitis

scientific article published on 23 May 2009

A Perspective on Roles Played by Innate and Adaptive Immunity in the Pathobiology of Neurodegenerative Disorders

scientific article

A Synthetic Agonist to Vasoactive Intestinal Peptide Receptor-2 Induces Regulatory T Cell Neuroprotective Activities in Models of Parkinson's Disease

scientific article published on 18 September 2019

A call for transparent reporting to optimize the predictive value of preclinical research

scientific article

A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection

scientific article published on October 2009

A functional transsulfuration pathway in the brain links to glutathione homeostasis

scientific article published on 27 September 2006

A long acting nanoformulated lamivudine ProTide

scientific article published on 05 September 2019

A long-acting 3TC ProTide nanoformulation suppresses HBV replication in humanized mice

scientific article published on 23 March 2020

A macrophage-nanozyme delivery system for Parkinson's disease

scientific article published on 31 August 2007

A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapy

scientific article published on 09 March 2017

A model of nitric oxide induced α-synuclein misfolding in Parkinson's disease ⬇️

scientific article published on July 7, 2012

A year-long extended release nanoformulated cabotegravir prodrug

scientific article published on 27 April 2020

AAV2/1 CD74 Gene Transfer Reduces β-amyloidosis and Improves Learning and Memory in a Mouse Model of Alzheimer's Disease.

scientific article

Activation of NR1a/NR2B receptors by monocyte-derived macrophage secretory products: implications for human immunodeficiency virus type one-associated dementia ⬇️

scientific article published on May 8, 2003

Active Targeted Macrophage-mediated Delivery of Catalase to Affected Brain Regions in Models of Parkinson?s Disease ⬇️

scientific article published on September 10, 2011

Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice

scientific article

Adaptive immune regulation of glial homeostasis as an immunization strategy for neurodegenerative diseases

scientific article

Adjunctive and long-acting nanoformulated antiretroviral therapies for HIV-associated neurocognitive disorders ⬇️

scientific article

Advances in neuroimaging for HIV-1 associated neurological dysfunction: clues to the diagnosis, pathogenesis and therapeutic monitoring.

scientific article

Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons

scientific article published on 27 November 2020

An Interactive Cluster Heat Map to Visualize and Explore Multidimensional Metabolomic Data

scientific article

Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages.

scientific article

Antiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG Mice.

scientific article

Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice

scientific article

Autophagy facilitates macrophage depots of sustained-release nanoformulated antiretroviral drugs

scientific article

Bench-to-bedside translation of magnetic nanoparticles

scientific article

Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages

scientific article published on 18 June 2012

Bioimaging predictors of rilpivirine biodistribution and antiretroviral activities

scientific article published on 14 September 2018

Blood-borne macrophage-neural cell interactions hitchhike on endosome networks for cell-based nanozyme brain delivery.

scientific article

Brain ingress of regulatory T cells in a murine model of HIV-1 encephalitis☆ ⬇️

scientific article published on September 16, 2010

Brain region mapping using global metabolomics

scientific article

Bridge between neuroimmunity and traumatic brain injury

scientific article

Broad Spectrum Mixed Lineage Kinase Type 3 Inhibition and HIV-1 Persistence in Macrophages

scientific article published on 07 January 2019

C1q-calreticulin induced oxidative neurotoxicity: relevance for the neuropathogenesis of Alzheimer's disease.

scientific article published in February 2003

CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction

scientific article

CCL2 affects β-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease

scientific article

CD 4+ T cells in the pathobiology of neurodegenerative disorders

scientific article published on 12 May 2009

CD4+ T cells from Copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

scientific article

CD4+ effector T cells accelerate Alzheimer's disease in mice

scientific article published on 19 November 2021

CD4+ regulatory and effector/memory T cell subsets profile motor dysfunction in Parkinson's disease

scientific article

CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice.

scientific article

CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic mice

scientific article

CRISPR-Cas9 Mediated Exonic Disruption for HIV-1 Elimination

scientific article published on 10 November 2021

CSF proteomic fingerprints for HIV-associated cognitive impairment

scientific article

Can Humanized Mice Reflect the Complex Pathobiology of HIV-Associated Neurocognitive Disorders? ⬇️

scientific article published on 07 January 2012

Cathepsin B Improves ß-Amyloidosis and Learning and Memory in Models of Alzheimer's Disease.

scientific article published on 13 December 2016

Cell Delivery of Therapeutic Nanoparticles ⬇️

scientific article published on January 1, 2011

Cell-mediated drug delivery.

scientific article

Cell-mediated transfer of catalase nanoparticles from macrophages to brain endothelial, glial and neuronal cells.

scientific article

Cellular Interactions and Signaling in neuroAIDS: Emerging Issues Colloquium

scientific article

Cellular Responses and Tissue Depots for Nanoformulated Antiretroviral Therapy

scientific article

Cerebrospinal Fluid Proteomic Profiling of HIV-1-Infected Patients with Cognitive Impairment

article

Changes in the plasma proteome follows chronic opiate administration in simian immunodeficiency virus infected rhesus macaques

scientific article published on 6 August 2011

Combinatorial assessments of brain tissue metabolomics and histopathology in rodent models of human immunodeficiency virus infection

scientific article

Commentary: Animal models of neuroAIDS.

scientific article published on 2 May 2012

Comparative manufacture and cell-based delivery of antiretroviral nanoformulations.

scientific article published on 20 December 2011

Control of neuroinflammation as a therapeutic strategy for amyotrophic lateral sclerosis and other neurodegenerative disorders

scientific article

Copolymer-1 induces adaptive immune anti-inflammatory glial and neuroprotective responses in a murine model of HIV-1 encephalitis

scientific article

Creation of a Long-Acting Nanoformulated 2',3'-Dideoxy-3'-Thiacytidine

scientific article published on 24 August 2016

Creation of a long-acting nanoformulated dolutegravir

scientific article published on 6 February 2018

Creation of a long-acting rilpivirine prodrug nanoformulation

scientific article published on 03 September 2019

Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles

scientific article

Cytoskeletal protein transformation in HIV-1-infected macrophage giant cells

scientific article

Defining the Innate Immune Responses for SARS-CoV-2-Human Macrophage Interactions

scientific article published on 04 October 2021

Design of mannosylated oral amphotericin B nanoformulation: efficacy and safety in visceral leishmaniasis

scientific article published on 31 January 2018

Development and characterization of a long-acting nanoformulated abacavir prodrug

scientific article

Development of HIV reservoir targeted long acting nanoformulated antiretroviral therapies

scientific article

Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery

scientific article

Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders

scientific article published on 21 June 2009

Development of a rapid autopsy program for studies of brain immunity.

scientific article published on 7 April 2005

Development of europium doped core-shell silica cobalt ferrite functionalized nanoparticles for magnetic resonance imaging

scientific article published on December 2016

Development of mannose-anchored thiolated amphotericin B nanocarriers for treatment of visceral leishmaniasis

scientific article published on 23 November 2016

Diagnostics for SARS-CoV-2 infections

scientific article published on 15 February 2021

Diminished matrix metalloproteinase 9 secretion in human immunodeficiency virus-infected mononuclear phagocytes: modulation of innate immunity and implications for neurological disease

scientific article published in December 2004

Dolutegravir Inhibition of Matrix Metalloproteinases Affects Mouse Neurodevelopment

scientific article published on 14 August 2021

Dual destructive and protective roles of adaptive immunity in neurodegenerative disorders

scientific article

Effects of pluronic and doxorubicin on drug uptake, cellular metabolism, apoptosis and tumor inhibition in animal models of MDR cancers.

scientific article

Enabling nanomaterial, nanofabrication and cellular technologies for nanoneuromedicines

scientific article

Endosomal trafficking of nanoformulated antiretroviral therapy facilitates drug particle carriage and HIV clearance.

scientific article

Enhancement of NMDA receptor-mediated excitatory postsynaptic currents by gp120-treated macrophages: implications for HIV-1-associated neuropathology.

scientific article published on 10 May 2013

Erratum to “CSF proteomic fingerprints for HIV-associated cognitive impairment”

article

Erratum: Proteomic analyses of monocytes obtained from Hispanic women with HIV-associated dementia show depressed antioxidants

article

Evaluation of the safety and immunomodulatory effects of sargramostim in a randomized, double-blind phase 1 clinical Parkinson's disease trial.

scientific article

Facilitated monocyte-macrophage uptake and tissue distribution of superparmagnetic iron-oxide nanoparticles

scientific article

Formulation design facilitates magnetic nanoparticle delivery to diseased cells and tissues

scientific article published on 19 March 2014

Functional Proteome of Macrophage Carried Nanoformulated Antiretroviral Therapy Demonstrates Enhanced Particle Carrying Capacity ⬇️

scientific article published on April 17, 2013

Functional Proteomic Analysis for Regulatory T Cell Surveillance of the HIV-1-Infected Macrophage ⬇️

scientific article published on November 4, 2010

GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxicated mice

scientific article published on 29 October 2013

Generation and Disease Model Relevance of a Manganese Enhanced Magnetic Resonance Imaging-Based NOD/scid-IL-2Rγc(null) Mouse Brain Atlas

scientific article published on 10 November 2015

Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis.

scientific article

Genomic and proteomic microglial profiling: pathways for neuroprotective inflammatory responses following nerve fragment clearance and activation

scientific article

Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS.

scientific article published on 16 December 2006

Granulocyte-macrophage colony stimulating factor exerts protective and immunomodulatory effects in cortical trauma

scientific article

Granulocyte-macrophage colony-stimulating factor mRNA and Neuroprotective Immunity in Parkinson's disease

scientific article published on 31 March 2021

Granulocyte-macrophage colony-stimulating factor neuroprotective activities in Alzheimer's disease mice

scientific article published on 17 March 2018

HIV and the Macrophage: From Cell Reservoirs to Drug Delivery to Viral Eradication.

scientific article published on 23 March 2018

HIV-1 cellular and tissue replication patterns in infected humanized mice

scientific article published on 21 March 2016

HIV-1 gp120 compromises blood-brain barrier integrity and enhances monocyte migration across blood-brain barrier: implication for viral neuropathogenesis

scientific article published on 10 May 2006

HIV-1 hijacks tunneling nanotubes and secretory microvesicles for intercellular spread in monocyte-derived macrophages

article

HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: new insights into blood-brain barrier dysfunction for HIV-1-associated dementia

scientific article published on 23 February 2007

HIV-1 neuroimmunity in the era of antiretroviral therapy.

scientific article

HIV-1 transforms the monocyte plasma membrane proteome ⬇️

scientific article published on 08 April 2009

HIV-1-Associated Left Ventricular Cardiac Dysfunction in Humanized Mice

scientific article published on 16 June 2020

HIV-1-associated dementia: a basic science and clinical perspective

scientific article

HIV-1-associated dementia: a metabolic encephalopathy perpetrated by virus-infected and immune-competent mononuclear phagocytes.

scientific article

HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta

scientific article published in November 2006

HIV-1-infected astrocytes and the microglial proteome.

scientific article published on 28 June 2008

Harnessing regulatory T cell neuroprotective activities for treatment of neurodegenerative disorders

scientific article published on 05 June 2020

Human Immunodeficiency Virus type 1 Endocytic Trafficking Through Macrophage Bridging Conduits Facilitates Spread of Infection ⬇️

scientific article published on July 26, 2011

Human Interleukin-34 facilitates microglia-like cell differentiation and persistent HIV-1 infection in humanized mice

article

Human dendritic cells transduced with herpes simplex virus amplicons encoding human immunodeficiency virus type 1 (HIV-1) gp120 elicit adaptive immune responses from human cells engrafted into NOD/SCID mice and confer partial protection against [...]

scientific article

Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice.

scientific article published on 20 December 2006

Human immunodeficiency virus-mononuclear phagocyte interactions: emerging avenues of biomarker discovery, modes of viral persistence and disease pathogenesis

scientific article published on July 2006

Hypersynchrony despite pathologically reduced beta oscillations in patients with Parkinson's disease: a pharmaco-magnetoencephalography study

scientific article

Immune Activations and Viral Tissue Compartmentalization During Progressive HIV-1 Infection of Humanized Mice

article

Immunization strategies for Parkinson's disease ⬇️

scientific article published on January 1, 2012

Immunoisolation of Nanoparticles Containing Endocytic Vesicles for Drug Quantitation ⬇️

scientific article published on January 1, 2013

Immunoregulation of a CB2 receptor agonist in a murine model of neuroAIDS

scientific article

Immunotherapy for Parkinson's disease

scientific article published on 21 January 2020

Impaired spatial cognition and synaptic potentiation in a murine model of human immunodeficiency virus type 1 encephalitis.

scientific article

Improved visualization of neuronal injury following glial activation by manganese enhanced MRI.

scientific article published on June 2013

Inflammation and Adaptive Immunity in Parkinson's Disease ⬇️

scientific article published on January 1, 2012

Influence of age, irradiation and humanization on NSG mouse phenotypes

scientific article

Ingress of blood-borne macrophages across the blood-brain barrier in murine HIV-1 encephalitis

scientific article published on 24 July 2008

Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis

scientific article published on 16 June 2005

Inhibition of long-term potentiation by interleukin-8: implications for human immunodeficiency virus-1-associated dementia

scientific article published on February 2003

Innate and adaptive immunity for the pathobiology of Parkinson's disease

scientific article published on September 2009

Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice

scientific article published on February 2007

Interview: Nanomedicine and the fight against HIV/AIDS.

scientific article published in February 2014

Investigating the human immunodeficiency virus type 1-infected monocyte-derived macrophage secretome

scientific article

Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson's disease.

scientific article

Isolation and HIV-1 infection of primary human microglia from fetal and adult tissue

scientific article

Isolation, propagation, and HIV-1 infection of monocyte-derived macrophages and recovery of virus from brain and cerebrospinal fluid

scientific article

Laboratory investigations for the morphologic, pharmacokinetic, and anti-retroviral properties of indinavir nanoparticles in human monocyte-derived macrophages

scientific article published on 25 September 2006

Landmark optimization using local curvature for point-based nonlinear rodent brain image registration

scientific article published on 26 September 2011

Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis

scientific article published in 2004

Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis

scientific article published in January 2004

Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis.

scientific article published in January 2004

Links between Progressive HIV-1 Infection of Humanized Mice and Viral Neuropathogenesis ⬇️

scientific article published on November 18, 2010

Lipids and cognition make good bedfellows for neuroAIDS.

scientific article

Lithium therapy for human immunodeficiency virus type 1-associated neurocognitive impairment.

scientific article published on April 2009

Long-Acting Parenteral Nanoformulated Antiretroviral Therapy: Interest and Attitudes of HIV-Infected Patients ⬇️

scientific article published on April 23, 2013

Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes.

scientific article

Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice.

scientific article

Long-acting slow effective release antiretroviral therapy

scientific article

Loss of neuronal integrity during progressive HIV-1 infection of humanized mice

scientific article

MEMRI is a biomarker defining nicotine-specific neuronal responses in subregions of the rodent brain

scientific article published on 15 February 2017

Macrophage Bridging Conduit Trafficking of HIV-1 Through the Endoplasmic Reticulum and Golgi Network ⬇️

scientific article published on June 6, 2011

Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS.

scientific article published on 17 June 2009

Macrophage delivery of therapeutic nanozymes in a murine model of Parkinson's disease

scientific article

Macrophage endocytic trafficking of antiretroviral nanoparticles

Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections

scientific article published on 13 May 2013

Macrophage-induced inflammation affects hippocampal plasticity and neuronal development in a murine model of HIV-1 encephalitis

scientific article published on December 2005

Macrophages offer a paradigm switch for CNS delivery of therapeutic proteins.

scientific article

Macrophages, chemokines and neuronal injury in HIV-1-associated dementia

scientific article

Magnetic resonance imaging of folic acid-coated magnetite nanoparticles reflects tissue biodistribution of long-acting antiretroviral therapy

scientific article published on 3 June 2015

Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice.

scientific article

Manganese-Enhanced Magnetic Resonance Imaging for Detection of Vasoactive Intestinal Peptide Receptor 2 Agonist Therapy in a Model of Parkinson's Disease

scientific article

Memantine protects hippocampal neuronal function in murine human immunodeficiency virus type 1 encephalitis.

scientific article

Methamphetamine-associated psychosis

scientific article

Methods development for blood borne macrophage carriage of nanoformulated antiretroviral drugs.

scientific article

Methods for Isolation and Identification of Nanoparticle-Containing Subcellular Compartments ⬇️

scientific article published on January 1, 2013

Modulating cellular autophagy for controlled antiretroviral drug release

scientific article published on 21 August 2018

Modulation of innate immunity by copolymer-1 leads to neuroprotection in murine HIV-1 encephalitis.

scientific article published on January 2008

Molecular characterization of a putative antiretroviral transcriptional factor, OTK18.

scientific article

Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration

scientific article

Monocyte chemotactic protein-1 regulates voltage-gated K+ channels and macrophage transmigration.

scientific article

Monocyte differentiation, activation, and mycobacterial killing are linked to transsulfuration-dependent redox metabolism

scientific article published on 17 October 2006

Mononuclear phagocyte immunity and the neuropathogenesis of HIV-1 infection ⬇️

scientific article published on November 1, 2003

Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells

scientific article

Mouse brain fixation to preserve In vivo manganese enhancement for ex vivo manganese‐enhanced MRI ⬇️

scientific article published on January 24, 2013

Multidimensional protein fractionation using ProteomeLab PF 2D for profiling amyotrophic lateral sclerosis immunity: A preliminary report

scientific article published on 12 September 2008

Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution

scientific article published in January 2018

Murine Motor and Behavior Functional Evaluations for Acute 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Intoxication ⬇️

scientific article published on March 24, 2011

Murine models for human immunodeficiency virus type 1-associated dementia: the development of new treatment testing paradigms

scientific article

NanoART synthesis, characterization, uptake, release and toxicology for human monocyte-macrophage drug delivery

scientific article

NanoART, neuroAIDS and CNS drug delivery

scientific article published on July 2009

Nanoformulated Antiretroviral Therapy Attenuates Brain Metabolic Oxidative Stress

scientific article published on 01 August 2018

Nanoformulated antiretroviral drug combinations extend drug release and antiretroviral responses in HIV-1-infected macrophages: implications for neuroAIDS therapeutics

scientific article

Nanoneuromedicines for degenerative, inflammatory, and infectious nervous system diseases.

scientific article

Nanotechnology: a focus on nanoparticles as a drug delivery system

scientific article published on September 2006

Neurodegenerative disorders and nanoformulated drug development

scientific article published on July 2009

Neuroinflammation, Oxidative Stress and the Pathogenesis of Parkinson's Disease

scientific article published on December 2006

Neuroinflammatory responses from microglia recovered from HIV-1-infected and seronegative subjects

scientific article published on June 2005

Neuromagnetic evidence of abnormal movement-related beta desynchronization in Parkinson's disease

scientific article

Neuromodulatory activities of CD4+CD25+ regulatory T cells in a murine model of HIV-1-associated neurodegeneration

scientific article published on March 2009

Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia ⬇️

scientific article published on May 1, 2003

Neuropathogenesis of human immunodeficiency virus infection

scientific article published in January 2018

Neuropathologic and neuroinflammatory activities of HIV-1-infected human astrocytes in murine brain

scientific article

Neuropharmacologic Approaches to Restore the Brain's Microenvironment.

scientific article published on 28 June 2016

Neuroprotective Activities of Long-Acting Granulocyte-Macrophage Colony-Stimulating Factor (mPDM608) in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Intoxicated Mice

scientific article published on 07 July 2020

Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease

scientific article published on 3 August 2007

Neuroprotective activities of CEP-1347 in models of neuroAIDS.

scientific article

Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.

scientific article published on October 2003

Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis.

scientific article published on September 2005

Neuroprotective strategies for HIV-1 associated dementia.

scientific article

Neuroregulatory events follow adaptive immune-mediated elimination of HIV-1-infected macrophages: studies in a murine model of viral encephalitis.

scientific article published on June 2004

Neurotheranostics as personalized medicines

scientific article published on 26 October 2018

Nitrated alpha-synuclein and microglial neuroregulatory activities

scientific article

Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons

scientific article

Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease

scientific article

Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsets

scientific article published on April 2009

Not just another jigsaw puzzle

scientific article

Novel delivery system enhances efficacy of antiretroviral therapy in animal model for HIV-1 encephalitis

scientific article

OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis

scientific article published in May 2004

Opendra “Bill” Narayan (1936–2007): A Personal Tribute to a Friend, Teacher, and Colleague

Opposing regulation of endolysosomal pathways by long-acting nanoformulated antiretroviral therapy and HIV-1 in human macrophages

scientific article

Optimizing the preparation and stability of decorated antiretroviral drug nanocrystals.

scientific article

Oxidative stress and the pathogenesis of neurodegenerative disorders

scientific article

Pathways towards an effective immunotherapy for Parkinson's disease

scientific article published on December 2011

Pathways towards human immunodeficiency virus elimination

scientific article published on 27 February 2020

Peripheral nerve induces macrophage neurotrophic activities: regulation of neuronal process outgrowth, intracellular signaling and synaptic function ⬇️

scientific article published on September 1, 2003

Persistent EcoHIV infection induces nigral degeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated mice.

scientific article published on 28 March 2018

Pharmacodynamic and antiretroviral activities of combination nanoformulated antiretrovirals in HIV-1-infected human peripheral blood lymphocyte-reconstituted mice.

scientific article published on 17 July 2012

Pharmacodynamics of folic acid receptor targeted antiretroviral nanotherapy in HIV-1-infected humanized mice

scientific article published on 27 May 2015

Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations

scientific article

Pharmacokinetic interactions of CEP-1347 and atazanavir in HIV-infected patients.

scientific article published on 05 June 2013

Pharmacokinetic testing of a first generation cabotegravir prodrug in rhesus macaques

scientific article published on 01 March 2019

Pharmacokinetics of a Long-Acting Nanoformulated Dolutegravir Prodrug in Rhesus Macaques

scientific article published on 23 October 2017

Pharmacokinetics, biodistribution, and toxicity of folic acid-coated antiretroviral nanoformulations

scientific article

Pharmacotherapeutics of SARS-CoV-2 Infections

scientific article

Pharmacotoxicology of monocyte-macrophage nanoformulated antiretroviral drug uptake and carriage ⬇️

scientific article published on December 22, 2010

Planning Future Strategies for Domestic and International NeuroAIDS Research, July 24-25, 2008

scientific article (publication date: September 2009)

Plasma proteomic analysis of simian immunodeficiency virus infection of rhesus macaques

scientific article published on September 2010

Plasma proteomic profiling in HIV-1 infected methamphetamine abusers

scientific article

Polyelectrolyte complex optimization for macrophage delivery of redox enzyme nanoparticles.

scientific article

Potential of N-acetylated-para-aminosalicylic acid to accelerate manganese enhancement decline for long-term MEMRI in rodent brain.

scientific article

Preclinical pharmacokinetics and tissue distribution of long-acting nanoformulated antiretroviral therapy

scientific article published on 22 April 2013

Presenilin-1 familial Alzheimer's disease mutation alters hippocampal neurogenesis and memory function in CCL2 null mice.

scientific article

ProTide generated long-acting abacavir nanoformulations

scientific article published on 01 July 2018

Prodrug Therapies for Infectious and Neurodegenerative Diseases

scientific article published on 26 February 2022

Proteomic analyses of monocytes obtained from Hispanic women with HIV-associated dementia show depressed antioxidants

scientific article

Proteomic analysis of mesenchymal to Schwann cell transdifferentiation

scientific article published on 16 June 2017

Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues

scientific article published on 17 April 2020

Proteomic biosignatures for monocyte-macrophage differentiation.

scientific article

Proteomic fingerprinting of HIV-1-infected human monocyte-derived macrophages: a preliminary report

scientific article

Proteomic fingerprinting of human immunodeficiency virus type 1-associated dementia from patient monocyte-derived macrophages: A case study

scientific article published in January 2004

Proteomic fingerprints distinguish microglia, bone marrow, and spleen macrophage populations

scientific article published in August 2005

Proteomic modeling for HIV-1 infected microglia-astrocyte crosstalk

scientific article

Proteomic studies of nitrated alpha-synuclein microglia regulation by CD4+CD25+ T cells

scientific article published on July 2009

Pulsed stable isotope labeling of amino acids in cell culture uncovers the dynamic interactions between HIV-1 and the monocyte-derived macrophage

scientific article

Quantitative 1H magnetic resonance spectroscopic imaging determines therapeutic immunization efficacy in an animal model of Parkinson's disease.

scientific article

Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson's disease

scientific article

Quantitative magnetic resonance and SPECT imaging for macrophage tissue migration and nanoformulated drug delivery

scientific article

Quiet connections: Reduced fronto-temporal connectivity in nondemented Parkinson's Disease during working memory encoding

scientific article published on 6 May 2016

Rapid and reliable quantitation of amino acids and myo-inositol in mouse brain by high performance liquid chromatography and tandem mass spectrometry ⬇️

scientific article published on February 28, 2012

Rebuilding synaptic architecture in HIV-1 associated neurocognitive disease: a therapeutic strategy based on modulation of mixed lineage kinase

scientific article published on October 2010

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring ⬇️

scientific article published on December 9, 2010

Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia.

scientific article published on October 2003

Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease

scientific article

Rilpivirine-associated aggregation-induced emission enables cell-based nanoparticle tracking

scientific article published on 07 December 2019

Rod-shape theranostic nanoparticles facilitate antiretroviral drug biodistribution and activity in human immunodeficiency virus susceptible cells and tissues

scientific article published on 01 January 2020

Rodent models for HIV-associated neurocognitive disorders.

scientific article published on February 2012

SARS-CoV-2 Infection Leads to Neurological Dysfunction

scientific article published on 23 May 2020

STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier

scientific article

Selective VIP Receptor Agonists Facilitate Immune Transformation for Dopaminergic Neuroprotection in MPTP-Intoxicated Mice

scientific article

Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

scholarly article

Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease

scientific article

Small magnetite antiretroviral therapeutic nanoparticle probes for MRI of drug biodistribution.

scientific article published on August 2013

Sodium Phenylbutyrate Controls Neuroinflammatory and Antioxidant Activities and Protects Dopaminergic Neurons in Mouse Models of Parkinson’s Disease ⬇️

scientific article published on June 18, 2012

Specific transfection of inflamed brain by macrophages: a new therapeutic strategy for neurodegenerative diseases

scientific article published on 19 April 2013

Surface-engineered multimodal magnetic nanoparticles to manage CNS diseases

scientific article published on 17 January 2019

Synthesis and Characterization of Long-Acting Darunavir Prodrugs

scientific article published on 03 December 2019

Synthesis and characterization of a long-acting emtricitabine prodrug nanoformulation

scientific article published on 07 August 2019

Synthesis of a long acting nanoformulated emtricitabine ProTide

scientific article published on 20 August 2019

Systemic HIV-1 Infection Produces a Unique Glial Footprint in Humanized Mouse Brains

scientific article published on 18 August 2017

Systemic HIV-1 infection produces a unique glial footprint in humanized mouse brains.

scientific article published on 26 October 2017

T cells and Parkinson's disease

scientific article published on 11 August 2017

TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia

scientific article published in March 2004

The Natural History, Pathobiology, and Clinical Manifestations of SARS-CoV-2 Infections

scientific article published on 21 July 2020

The Promise of Long-Acting Antiretroviral Therapies: From Need to Manufacture

scientific article published on 10 April 2019

The cortical signature of symptom laterality in Parkinson's disease

scientific article published on 12 February 2017

The mixed lineage kinase-3 inhibitor URMC-099 improves therapeutic outcomes for long-acting antiretroviral therapy

scientific article published on 12 October 2015

The mixed-lineage kinase 3 inhibitor URMC-099 facilitates microglial amyloid-β degradation

scientific article published on 11 July 2016

The neuropathogenesis of HIV-1 infection

scientific article published on 01 January 2007

The promise and perils of CNS drug delivery: a video debate.

scientific article published in June 2008

The promise of nanoneuromedicine

scientific article published on 01 February 2014

Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease

scholarly article

Therapeutic immunization with a glatiramer acetate derivative does not alter survival in G93A and G37R SOD1 mouse models of familial ALS

scientific article published on 30 December 2006

Tracking superparamagnetic iron oxide labeled monocytes in brain by high-field magnetic resonance imaging

scientific article

UPLC-MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues

scientific article published on July 2011

URMC-099 facilitates amyloid-β clearance in a murine model of Alzheimer's disease.

scientific article

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