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List of works by Lorraine Clark

A Drosophila Model of Essential Tremor.

scientific article

A comprehensive screening of copy number variability in dementia with Lewy bodies

scientific article published on 24 October 2018

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci

scientific journal article

A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies

scientific article published on June 2013

Action Tremor Asymmetry Profile Does Not Aggregate in Families with Essential Tremor

scientific article

Age-specific penetrance of LRRK2 G2019S in the Michael J. Fox Ashkenazi Jewish LRRK2 Consortium

scientific article published on 10 June 2015

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

scientific article

Analysis of an early-onset Parkinson's disease cohort for DJ-1 mutations.

scientific article

Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies

scientific article published on 29 January 2020

Application of the Movement Disorder Society prodromal criteria in healthy G2019S-LRRK2 carriers

scientific article published on 30 March 2018

Association of glucocerebrosidase mutations with dementia with lewy bodies

scientific article published on May 2009

Candidate sequence variants and fetal hemoglobin in children with sickle cell disease treated with hydroxyurea

scientific article

Case-control study of the parkin gene in early-onset Parkinson disease

scientific article

Clinical and Pathological Characteristics of LRRK2 G2019S Patients with PD ⬇️

scientific article published on December 23, 2011

Clinical classification of borderline cases in the family study of essential tremor: an analysis of phenotypic features

scientific article published on 10 February 2014

Clinical correlations with Lewy body pathology in LRRK2-related Parkinson disease

scientific article

Cognitive and motor function in long-duration PARKIN-associated Parkinson disease

scientific article published on January 2014

Construction and validation of a Parkinson's disease mutation genotyping array for the Parkin gene

scientific article published in May 2007

Copy number variation of in familial dystonic tremor

scientific article published on 04 February 2019

Copy-number disorders are a common cause of congenital kidney malformations

scientific article

Creation of an open-access, mutation-defined fibroblast resource for neurological disease research

scientific article

Current Opinions and Consensus for Studying Tremor in Animal Models

scientific article published on 01 December 2019

Does rate of progression run in essential tremor families? Slower vs. faster progressors ⬇️

scientific article published on October 31, 2012

Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau

scientific article

Early Head Tremor in Essential Tremor: A Case Series and Commentary

scientific article published on 25 March 2017

Essential Tremor in a Charcot-Marie-Tooth Type 2C Kindred Does Not Segregate with the TRPV4 R269H Mutation

scientific article published on 22 January 2014

Estrogen receptor β variants modify risk for Alzheimer's disease in a multiethnic female cohort

scientific article published in January 2014

Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome

article

Expanded genetic screening panel for the Ashkenazi Jewish population.

scientific article published on 3 September 2015

Familial Aggregation and Co-Aggregation of Essential Tremor and Parkinson's Disease

scientific article published on 26 November 2015

Familial Aggregation of Cranial Tremor in Familial Essential Tremor ⬇️

scientific article published on May 25, 2013

Familial Aggregation of the Cerebellar Signs in Familial Essential Tremor

scientific article published on 13 January 2017

Familial versus Sporadic Essential Tremor: What Patterns Can One Decipher in Age of Onset?

scientific article published on 7 May 2015

Frequency of GBA variants in autopsy-proven multiple system atrophy

scientific article published on 3 April 2017

Frequency of known mutations in early-onset Parkinson disease: implication for genetic counseling: the consortium on risk for early onset Parkinson disease study

scientific article published in September 2010

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

scientific article published in January 2018

Gene-wise association of variants in four lysosomal storage disorder genes in neuropathologically confirmed Lewy body disease

scientific article

Genetic Testing Preferences of Individuals in Families with Essential Tremor

scientific article published on 27 March 2018

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.

scientific article

Genetic and Clinical Predictors of Deep Brain Stimulation in Young-Onset Parkinson's Disease

scientific article published on 18 January 2016

Genetic variants of α-synuclein are not associated with essential tremor

scientific article published on 24 October 2011

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

scientific article published on 15 February 2021

Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases

scientific article published on 2 November 2015

Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population

scientific journal article

Genome-wide association study in essential tremor identifies three new loci

scientific article published on 20 October 2016

Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes

scientific article

Heritability and genetic variance of dementia with Lewy bodies

scientific article published on 03 April 2019

High-depth whole genome sequencing of a large population-specific reference panel: Enhancing sensitivity, accuracy, and imputation

High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation.

scientific article published on 28 April 2018

Identification of candidate genes for familial early-onset essential tremor

scientific article published on 28 October 2015

Interest in genetic testing in Ashkenazi Jewish Parkinson's disease patients and their unaffected relatives

scientific article

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

scientific article published on 16 December 2017

Knowledge about Essential Tremor: A Study of Essential Tremor Families

scientific article published on 26 January 2018

LINGO1 and LINGO2 variants are associated with essential tremor and Parkinson disease

scientific article

Lack of Familial Aggregation of the “Essential-Tremor-Plus” Phenotype in Familial Essential Tremor

scientific article published in 2022

Lack of association between cancer history and PARKIN genotype: A family based study in PARKIN/Parkinson's Families ⬇️

scientific article published on August 24, 2012

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

scientific article (publication date: September 2014)

Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.

scientific article

Michael J. Fox Foundation LRRK2 Consortium: geographical differences in returning genetic research data to study participants

scientific article

Motor phenotype of LRRK2 G2019S carriers in early-onset Parkinson disease

scientific article

Mutations in the Parkinson's disease genes, Leucine Rich Repeat Kinase 2 (LRRK2) and Glucocerebrosidase (GBA), are not associated with essential tremor

scientific article

Neuropsychological Profile of Parkin Mutation Carriers with and without Parkinson Disease: The CORE-PD Study

scientific article

Neuropsychological performance in LRRK2 G2019S carriers with Parkinson's disease

scientific article

Nonmotor symptoms in healthy Ashkenazi Jewish carriers of the G2019S mutation in the LRRK2 gene

scientific article published on 21 March 2015

Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia

scientific article published on 22 March 2021

Olfactory identification in LRRK2 G2019S mutation carriers: a relevant marker?

scientific article

PCDH10 promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis

scientific article

Parkinson disease phenotype in Ashkenazi Jews with and without LRRK2 G2019S mutations

scientific article published on 15 October 2013

Parkinson's disease with Lewy bodies associated with a heterozygous PARKIN dosage mutation

scientific article published on 27 December 2013

Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease

scientific article

Pilot association study of the beta-glucocerebrosidase N370S allele and Parkinson's disease in subjects of Jewish ethnicity

scientific article published on January 2005

Placental overgrowth in mice lacking the imprinted gene Ipl

scientific article

Polyamine pathway contributes to the pathogenesis of Parkinson disease ⬇️

scientific article published on September 13, 2010

Predicting age of onset in familial essential tremor: how much does age of onset run in families?

scientific article published on 24 January 2013

Predictors of parkin mutations in early-onset Parkinson disease: the consortium on risk for early-onset Parkinson disease study

scientific article published in June 2010

Prevalence and features of unreported dystonia in a family study of “pure” essential tremor ⬇️

scientific article published on October 23, 2012

Promoter methylation-mediated inactivation of PCDH10 in acute lymphoblastic leukemia contributes to chemotherapy resistance

scientific article published on 24 August 2011

RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk

scientific article

REM sleep behavior disorder, as assessed by questionnaire, in G2019S LRRK2 mutation PD and carriers

scientific article

Replication of the LINGO1 gene association with essential tremor in a North American population

scientific article

Risk of Parkinson disease in carriers of parkin mutations: estimation using the kin-cohort method

scientific article

SMPD1 mutations, activity, and α-synuclein accumulation in Parkinson's disease

scientific article published on 20 February 2019

SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk

scientific article

Self-report of cognitive impairment and mini-mental state examination performance in PRKN, LRRK2, and GBA carriers with early onset Parkinson's disease

scientific article

Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins

scientific article

The MAPT H1 haplotype is associated with tangle-predominant dementia ⬇️

scientific article published on July 17, 2012

The Saitohin 'Q7R' polymorphism and tau haplotype in multi-ethnic Alzheimer disease and Parkinson's disease cohorts

scientific article published in August 2003

The effect of MAPT haplotype on neocortical Lewy body pathology in Parkinson disease

scientific article published on 20 April 2016

The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study

scientific article

The spiral axis as a clinical tool to distinguish essential tremor from dystonia cases

scientific article

Transient, Isolated Head Tremor in "Unaffected" Individuals: Is Essential Tremor an Even More Prevalent Disease Than We Suppose?

scientific article published on 13 July 2018

Validity of probands' reports and self-reports of essential tremor: Data from a large family study in North America

scientific article published on 06 August 2018

Whole genome sequencing and rare variant analysis in essential tremor families

scientific article published on 12 August 2019

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