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List of works by William K Scott

A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium

scientific article

A Locus at 5q33.3 Confers Resistance to Tuberculosis in Highly Susceptible Individuals.

scientific article

A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa.

scientific article

A genome-wide linkage analysis of dementia in the Amish

scientific article published on March 2006

A genome-wide linkage screen in the Amish with Parkinson disease points to chromosome 6

scientific article

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

scientific article published on 21 December 2015

A new locus for familial FSGS on chromosome 2p

scientific article

A novel ARMS2 splice variant is identified in human retina

scientific article published on 22 November 2011

A population-specific reference panel empowers genetic studies of Anabaptist populations

scientific article

A rare novel deletion of the tyrosine hydroxylase gene in Parkinson disease

scientific article

AMISH EYE STUDY: Baseline Spectral Domain Optical Coherence Tomography Characteristics of Age-Related Macular Degeneration

scientific article published on 01 August 2019

Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease

scientific article

Absence of mutation in the beta- and gamma-synuclein genes in familial autosomal dominant Parkinson's disease.

scientific article

Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample

scientific article (publication date: 26 January 2017)

Age at onset in two common neurodegenerative diseases is genetically controlled

scientific article published on March 2002

An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease

scientific article published in May 1999

An autosomal genomic screen for dementia in an extended Amish family

scientific article published in May 2005

Analysis of European mitochondrial haplogroups with Alzheimer disease risk

scientific article

Analysis of association between Alzheimer disease and the K variant of butyrylcholinesterase (BCHE-K)

scientific article published on 01 July 1999

Analysis of single nucleotide polymorphisms in the NOS2A gene and interaction with smoking in age-related macular degeneration

scientific article

Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration

scientific article published on 25 February 2010

Apolipoprotein E controls the risk and age at onset of Parkinson disease

scientific article published in June 2004

Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease

scientific article published in September 1997

Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses

scientific article published on September 2016

Association between bleomycin hydrolase and Alzheimer's disease in caucasians

scientific article published in November 1998

Association of SLC11A1 with tuberculosis and interactions with NOS2A and TLR2 in African-Americans and Caucasians.

scientific article

Association of Single-Nucleotide Polymorphisms of the Tau Gene With Late-Onset Parkinson Disease ⬇️

scientific article published on November 14, 2001

Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis

scientific article published on 22 August 2019

Association of the apolipoprotein E gene with age-related macular degeneration: possible effect modification by family history, age, and gender

scientific article published on 31 December 2000

Association study of Parkin gene polymorphisms with idiopathic Parkinson disease

scientific article published on July 2003

Author Correction: A population-specific reference panel empowers genetic studies of Anabaptist populations.

scientific article published on 25 April 2018

Autophagy is redundant for the host defense against systemic Candida albicans infections.

scientific article

C3 R102G polymorphism increases risk of age-related macular degeneration

scientific article

C9ORF72 intermediate repeat copies are a significant risk factor for Parkinson disease

scientific article published on 12 July 2013

CD4 intragenic SNPs associate with HIV-2 plasma viral load and CD4 count in a community-based study from Guinea-Bissau, West Africa

scientific article published on January 2011

Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans

scientific article

Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration

scientific article

Coding variants in ARMS2 and the risk of age-related macular degeneration

scientific article published in June 2013

Cognitive and motor function in long-duration PARKIN-associated Parkinson disease

scientific article published on January 2014

Cognitive performance of GBA mutation carriers with early-onset PD: the CORE-PD study.

scientific article

Combinatorial Mismatch Scan (CMS) for loci associated with dementia in the Amish

scientific article

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

scientific article

Comparing age-related macular degeneration phenotype in probands from singleton and multiplex families

scientific article published in May 2005

Complement factor H increases risk for atrophic age-related macular degeneration

scientific article published on 07 July 2006

Complement factor H variant increases the risk of age-related macular degeneration

scientific article (publication date: 15 April 2005)

Complete genomic screen for disease susceptibility loci in nuclear families

scientific article published on 01 January 1999

Complete genomic screen in Parkinson disease: evidence for multiple genes.

scientific article

Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.

scientific article published in October 1997

Complete genomic screen in late-onset familial Alzheimer's disease

scientific article published in January 1998

Complicated Staphylococcus aureus Bacteremia (SAB) Is Associated with Genetic Variation in GLS2.

scientific article published on 4 October 2017

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database

scientific article

Construction and validation of a Parkinson's disease mutation genotyping array for the Parkin gene

scientific article published in May 2007

Correction: Interleukin 12B (IL12B) Genetic Variation and Pulmonary Tuberculosis: A Study of Cohorts from The Gambia, Guinea-Bissau, United States and Argentina

scientific article published in PLoS ONE

Correction: Interleukin 12B (IL12B) Genetic Variation and Pulmonary Tuberculosis: A Study of Cohorts from The Gambia, Guinea-Bissau, United States and Argentina

Correction: Interleukin 12B (IL12B) Genetic Variation and Pulmonary Tuberculosis: A Study of Cohorts from The Gambia, Guinea-Bissau, United States and Argentina

Correction: Interleukin 12B (IL12B) Genetic Variation and Pulmonary Tuberculosis: A Study of Cohorts from The Gambia, Guinea-Bissau, United States and Argentina.

scientific article

Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study

scientific article published on 5 December 2011

DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma

scientific article

DNA variants in CACNA1C modify Parkinson disease risk only when vitamin D level is deficient

scientific article

Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration

scientific article published on 15 December 2007

Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities

scientific journal article

Design of the Genetics of Early Onset Cardiovascular Disease (GENECARD) study

scientific article published in April 2003

Detailed analysis of allelic variation in the ABCA4 gene in age-related maculopathy

scientific article

Dissecting A Complex Disease Using Modern Techniques of Molecular Biology

article

Dissection of chromosome 16p12 linkage peak suggests a possible role for CACNG3 variants in age-related macular degeneration susceptibility

scientific article

Epiregulin (EREG) and human V-ATPase (TCIRG1): genetic variation, ethnicity and pulmonary tuberculosis susceptibility in Guinea-Bissau and The Gambia.

scientific article published on 5 June 2014

Estimating cumulative pathway effects on risk for age-related macular degeneration using mixed linear models

scientific article published on 14 October 2015

Estrogen pathway polymorphisms in relation to primary open angle glaucoma: an analysis accounting for gender from the United States

scientific article published on 12 July 2013

Evaluating power and type 1 error in large pedigree analyses of binary traits

scientific article

Evidence for anticipation in autosomal dominant limb-girdle muscular dystrophy

scientific article

Examination of candidate exonic variants for association to Alzheimer disease in the Amish

scientific article

False positive rates in a genomic screen for complex quantitative traits

scientific article published on 01 January 1997

Family-based case-control study of MAOA and MAOB polymorphisms in Parkinson disease

scientific article published in December 2006

Family-based case-control study of cigarette smoking and Parkinson disease

scientific article published on 01 February 2005

Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease

scientific article

Fine mapping and genetic heterogeneity in the pure form of autosomal dominant familial spastic paraplegia

article

Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity

scientific article

Frequency of known mutations in early-onset Parkinson disease: implication for genetic counseling: the consortium on risk for early onset Parkinson disease study

scientific article published in September 2010

Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6

scientific article

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

scientific article published on January 2013

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

scientific article published in January 2018

Further evidence linking late-onset Alzheimer disease with chromosome 12.

scientific article published in February 1999

Gene-gene interaction between FGF20 and MAOB in Parkinson disease

scientific article

Generation of disease-specific autopsy-confirmed iPSCs lines from postmortem isolated Peripheral Blood Mononuclear Cells

scientific article published on 4 November 2016

Genetic Association Analysis of Drusen Progression

scientific article published on April 2016

Genetic analysis of complex diseases

scientific article published on 01 February 1997

Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: a multi-cohort analysis

scientific article published on 30 August 2017

Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis

scientific journal article

Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease

scientific article published on 01 April 2003

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

scientific article (2010)

Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia

scientific article

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

scientific article published on 11 January 2016

Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene

scientific journal article

Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease

scientific article

Genome-wide brain DNA methylation analysis suggests epigenetic reprogramming in Parkinson disease

scientific article published on 24 June 2019

Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee

scientific article published in August 2011

Genome-wide linkage screen in familial Parkinson disease identifies loci on chromosomes 3 and 18

scientific article published on 26 March 2009

Genomewide Association Study of Retinal Traits in the Amish Reveals Loci Influencing Drusen Development and Link to Age-Related Macular Degeneration

scientific article published in 2022

Genomics of human pulmonary tuberculosis: from genes to pathways.

scientific article published on 12 October 2017

Genotype at polymorphism rs11200638 and HTRA1 expression level ⬇️

scientific article published on November 1, 2010

Glutamate receptor gene GRIN2A, coffee, and Parkinson disease

scientific article

Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease

scientific article (publication date: 15 December 2003)

Haplotypes spanning the complement factor H gene are protective against age-related macular degeneration

scientific article published on 01 September 2007

Heritability of Choroidal Thickness in the Amish.

scientific article published on 19 October 2016

High-resolution survey in familial Parkinson disease genes reveals multiple independent copy number variation events in PARK2

scientific article published on 28 May 2013

Human genetic susceptibility to Candida infections.

scientific article published on 04 June 2012

Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia

scientific article published on 05 October 2018

Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma

scientific article

Identification of Novel Genes in Late-Onset Alzheimer's Disease

article

Identifying consensus disease pathways in Parkinson's disease using an integrative systems biology approach

scientific article

Independent effects of complement factor H Y402H polymorphism and cigarette smoking on risk of age-related macular degeneration

scientific article published on 22 January 2007

Interleukin 12B (IL12B) genetic variation and pulmonary tuberculosis: a study of cohorts from The Gambia, Guinea-Bissau, United States and Argentina

scientific article

Inverse association of female hormone replacement therapy with age-related macular degeneration and interactions with ARMS2 polymorphisms

scientific article

Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1.

scientific article published in August 2017

Joint effects of smoking history and APOE genotypes in age-related macular degeneration

scientific article published on 4 November 2005

Lack of association between apolipoprotein E genotype and sporadic amyotrophic lateral sclerosis

scientific article published in March 1998

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

scientific article (publication date: September 2014)

Life after the screen: making sense of many P-values

scientific article published on 01 January 2001

Linkage and association of successful aging to the 6q25 region in large Amish kindreds

scientific article published on 07 July 2012

Linkage disequilibrium and haplotype tagging polymorphisms in the Tau H1 haplotype

scientific article published on 8 June 2004

Linkage disequilibrium inflates type I error rates in multipoint linkage analysis when parental genotypes are missing

scientific article published on 26 July 2005

Linkage of Parkinsonism and Alzheimer's disease with Lewy body pathology to chromosome 12

scientific article published on 01 October 2002

Linkage of a gene causing familial membranoproliferative glomerulonephritis type III to chromosome 1

scientific article (publication date: August 2002)

Linkage of familial essential tremor to chromosome 5q35.

scientific article

Linkage of the CCR5 Delta 32 mutation with a functional polymorphism of CD45RA

scientific article published on 01 July 2000

Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondria

scientific article

Locus heterogeneity, anticipation and reduction of the chromosome 2p minimal candidate region in autosomal dominant familial spastic paraplegia

scientific article published on 01 September 1997

Longitudinal follow-up of late-onset Alzheimer disease families.

scientific article published on July 2008

Lower Levels of Education Are Associated with Cognitive Impairment in the Old Order Amish

scientific article published on 01 December 2020

MCP1 SNPs and pulmonary tuberculosis in cohorts from West Africa, the USA and Argentina: lack of association or epistasis with IL12B polymorphisms

scientific article

Maternal lineages and Alzheimer disease risk in the Old Order Amish

scientific article published on 28 October 2005

Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele.

scientific article published on July 1999

Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.

scientific article

Methods for interaction analyses using family-based case-control data: conditional logistic regression versus generalized estimating equations

scientific article

Methylome-wide analysis reveals epigenetic marks associated with resistance to tuberculosis in HIV-infected individuals from East Africa

scientific article published on 05 January 2021

Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson Disease

scientific article (publication date: April 2003)

Mitochondrial haplogroup X is associated with successful aging in the Amish

scientific article published on 13 July 2011

Motivations for Participation in Parkinson Disease Genetic Research Among Hispanics versus Non-Hispanics

scientific article published on 16 July 2019

Motor phenotype of LRRK2 G2019S carriers in early-onset Parkinson disease

scientific article

NOS2A and the modulating effect of cigarette smoking in Parkinson's disease

scientific article published in September 2006

NOS2A, TLR4, and IFNGR1 interactions influence pulmonary tuberculosis susceptibility in African-Americans

scientific article

Neovascular age-related macular degeneration and its association with LOC387715 and complement factor H polymorphism

scientific article published on 01 January 2007

Neuropsychological Profile of Parkin Mutation Carriers with and without Parkinson Disease: The CORE-PD Study

scientific article

Nitric oxide synthase genes and their interactions with environmental factors in Parkinson's disease

scientific article published on 29 July 2008

No association between the HLA-A2 allele and Alzheimer disease.

scientific article published on September 1999

No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset Alzheimer disease patients

scientific article

No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease

scientific article published in 1997

No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease

scientific article published in March 1998

Novel Variants in <i>LRRK2</i> and <i>GBA</i> Identified in Latino Parkinson Disease Cohort Enriched for Caribbean Origin

scientific article published on 12 November 2020

Olfaction in Parkin heterozygotes and compound heterozygotes: the CORE-PD study.

scientific article

Ordered subset linkage analysis supports a susceptibility locus for age-related macular degeneration on chromosome 16p12

scientific article

Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22.

scientific article

Overall diet quality and age-related macular degeneration

scientific article published on January 2010

Overlap between Parkinson disease and Alzheimer disease in ABCA7 functional variants

scientific article published on 14 January 2016

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease

scientific article

Parkin mutations and susceptibility alleles in late-onset Parkinson's disease

article

Parkinson disease loci in the mid-western Amish

scientific journal article

Peripheral reticular pigmentary change is associated with complement factor H polymorphism (Y402H) in age-related macular degeneration

scientific article published on 11 December 2007

Pesticide exposure and risk of Parkinson's disease: a family-based case-control study

scientific article

Phenotype analysis of patients with the risk variant LOC387715 (A69S) in age-related macular degeneration

scientific article published on 03 December 2007

Population-based case-control association studies

scientific article published in July 2012

Population-based case-control association studies

scientific article published in January 2007

Potential for expanded power in linkage studies using the ALLEGRO and MERLIN software programs

scientific article

Predictors of parkin mutations in early-onset Parkinson disease: the consortium on risk for early-onset Parkinson disease study

scientific article published in June 2010

Presenilin-1 polymorphism and Alzheimer's disease

scientific article published on 01 April 1996

Presenilin-1 polymorphism and Alzheimer's disease

scientific article published on 01 June 1996

Progression Rate From Intermediate to Advanced Age-Related Macular Degeneration Is Correlated With the Number of Risk Alleles at the CFH Locus

scientific article

Protective effect of complement factor B and complement component 2 variants in age-related macular degeneration

scientific article published on 18 June 2007

Rare complement factor H variant associated with age-related macular degeneration in the Amish

scientific article

Rare variant APOC3 R19X is associated with cardio-protective profiles in a diverse population-based survey as part of the Epidemiologic Architecture for Genes Linked to Environment Study

scientific article

Rare variants and loci for age-related macular degeneration in the Ohio and Indiana Amish

scientific article published on 31 July 2019

Reply

Revealing the role of glutathione S-transferase omega in age-at-onset of Alzheimer and Parkinson diseases

scientific article

Role of autophagy genetic variants for the risk of Candida infections.

scientific article

Searching for epistatic interactions in nuclear families using conditional linkage analysis

scientific article published on 30 December 2005

Self-report of cognitive impairment and mini-mental state examination performance in PRKN, LRRK2, and GBA carriers with early onset Parkinson's disease

scientific article

Seven new loci associated with age-related macular degeneration

scientific article

Smoking, caffeine, and nonsteroidal anti-inflammatory drugs in families with Parkinson disease

scientific article (publication date: April 2007)

Successful aging shows linkage to chromosomes 6, 7, and 14 in the Amish

scientific article published on July 2011

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

scientific article published in February 2018

The ARMS2 A69S variant and bilateral advanced age-related macular degeneration

scientific article

The Application of Genetic Risk Scores in Age-Related Macular Degeneration: A Review

scientific article

The Carnitine Shuttle Pathway is Altered in Patients With Neovascular Age-Related Macular Degeneration

scientific article published on 01 October 2018

The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease

scientific article published in August 2003

The Relationship Between Reticular Pseudodrusen and Severity of AMD

scientific article published on 8 December 2015

The impact of caspase-12 on susceptibility to candidemia

scientific article published on 25 June 2011

The relation between depression and parkin genotype: the CORE-PD study

scientific article published on December 2011

The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study

scientific article

The α-synuclein gene is not a major risk factor in familial Parkinson disease

article

Toll-like receptor 1 polymorphisms increase susceptibility to candidemia.

scientific article published on February 2012

Using genetic variation and environmental risk factor data to identify individuals at high risk for age-related macular degeneration

scientific article (publication date: 24 March 2011)

Variants at chromosome 10q26 locus and the expression of HTRA1 in the retina

scientific article

Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African-Americans, and West Africans

scientific article

Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein

scientific article published on 31 January 2008

Vitamin D from different sources is inversely associated with Parkinson disease

scientific article

Vitamin D receptor gene as a candidate gene for Parkinson disease

scientific article

Whole exome sequencing of extreme age-related macular degeneration phenotypes

scientific article published on 29 August 2016

Whole exome sequencing of rare variants in EIF4G1 and VPS35 in Parkinson disease

scientific article published on 13 February 2013

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