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List of works by Karel Pacak

15 YEARS OF PARAGANGLIOMA: Imaging and imaging-based treatment of pheochromocytoma and paraganglioma

scientific article

18F-FDG PET/CT as a predictor of hereditary head and neck paragangliomas

scientific article published on January 2014

18F-FLT PET/CT in the Evaluation of Pheochromocytomas and Paragangliomas: A Pilot Study

scientific article

68Ga-DOTATATE PET/CT in the Localization of Head and Neck Paragangliomas Compared with Other Functional Imaging Modalities and CT/MRI

scientific article published on 12 November 2015

A Large Adrenal Tumor With Marked 18F-Fluorodeoxyglucose Uptake

scientific article published in July 2017

A clinical overview of pheochromocytomas/paragangliomas and carcinoid tumors

scientific article published on August 2008

A new specific succinate-glutamate metabolomic hallmark in SDHx-related paragangliomas

scientific article

A novel EPAS1/HIF2A germline mutation in a congenital polycythemia with paraganglioma ⬇️

scientific article published on October 23, 2012

A reduction in Pten tumor suppressor activity promotes ErbB-2-induced mouse prostate adenocarcinoma formation through the activation of signaling cascades downstream of PDK1.

scientific article published on 14 May 2009

Accuracy of recommended sampling and assay methods for the determination of plasma-free and urinary fractionated metanephrines in the diagnosis of pheochromocytoma and paraganglioma: a systematic review.

scientific article published on 12 April 2017

Adenoviral gene transfer in bovine adrenomedullary and murine pheochromocytoma cells: potential clinical and therapeutic relevance

scientific article published on 24 May 2007

Adverse drug reactions in patients with phaeochromocytoma: incidence, prevention and management

scientific article published on January 2007

Age at Diagnosis of Pheochromocytoma Differs According to Catecholamine Phenotype and Tumor Location ⬇️

scientific article published on December 8, 2010

Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints.

scientific article published on 7 June 2018

An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers

An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis

scientific article

Anatomical and functional imaging of metastatic pheochromocytoma

scientific article published in June 2004

Anatomical and functional imaging of tumors in animal models: focus on pheochromocytoma

scientific article published on August 2006

Animal models of pheochromocytoma including NIH initial experience

scientific article published in August 2006

Anti-cancer potential of MAPK pathway inhibition in paragangliomas-effect of different statins on mouse pheochromocytoma cells

scientific article

Are patients with hormonally functional phaeochromocytoma and paraganglioma initially receiving a proper adrenoceptor blockade? A retrospective cohort study

scientific article published on 21 March 2016

Association between acute sympathetic response, early onset vasospasm, and delayed vasospasm following spontaneous subarachnoid hemorrhage

scientific article

Association between neuroendocrine tumors biomarkers and primary tumor site and disease type based on total 68Ga-DOTATATE-Avid tumor volume measurements

scientific article

Association between sympathetic response, neurogenic cardiomyopathy, and venous thromboembolization in patients with primary subarachnoid hemorrhage ⬇️

scientific article published on May 1, 2013

Association of urinary bladder paragangliomas with germline mutations in the SDHB and VHL genes

scientific article published on 13 February 2015

Behavioral, adrenal, and sympathetic responses to long-term administration of an oral corticotropin-releasing hormone receptor antagonist in a primate stress paradigm

scientific article published in November 2004

Biochemical and clinical manifestations of dopamine-producing paragangliomas: utility of plasma methoxytyramine

scientific article published on 11 January 2005

Biochemical diagnosis and localization of pheochromocytoma: can we reach a consensus?

scientific article published in August 2006

Biochemical diagnosis of pheochromocytoma

scientific article published on January 2004

Biochemical diagnosis of pheochromocytoma: how to distinguish true- from false-positive test results

scientific article

Biochemical diagnosis of pheochromocytoma: which test is best?

scientific article (publication date: 20 March 2002)

Biochemically silent abdominal paragangliomas in patients with mutations in the succinate dehydrogenase subunit B gene

scientific article published on 07 October 2008

Blood collection in unstressed, conscious, and freely moving mice through implantation of catheters in the jugular vein: a new simplified protocol

Bortezomib Alone and in Combination With Salinosporamid A Induces Apoptosis and Promotes Pheochromocytoma Cell Death In Vitro and in Female Nude Mice

scientific article published on 15 August 2017

Brief communication: radiographic contrast infusion and catecholamine release in patients with pheochromocytoma

scientific article

Brown fat imaging with (18)F-6-fluorodopamine PET/CT, (18)F-FDG PET/CT, and (123)I-MIBG SPECT: a study of patients being evaluated for pheochromocytoma

scientific article published on 15 June 2007

CHARACTERISTICS AND OUTCOMES OF METASTATIC SDHB AND SPORADIC PHEOCHROMOCYTOMA/PARAGANGLIOMA: AN NATIONAL INSTITUTES OF HEALTH STUDY.

scientific article published on 2 November 2015

CSF Catecholamine Profile in Subarachnoid Hemorrhage Patients with Neurogenic Cardiomyopathy ⬇️

scientific article published on June 1, 2011

Candidate genes associated with malignant pheochromocytomas by genome-wide expression profiling.

scientific article published in December 2009

Carboxypeptidase E: elevated expression correlated with tumor growth and metastasis in pheochromocytomas and other cancers

scientific article

Cardiac sympathetic denervation preceding motor signs in Parkinson disease

scientific article

Cardiac sympathetic denervation preceding motor signs in Parkinson disease*

scientific article published in April 2009

Cardiac uptake-1 inhibition by high circulating norepinephrine levels in patients with pheochromocytoma

scientific article published on 12 April 2004

Cardiometabolic risk factors and health behaviors in family caregivers

scientific article

Carney triad can be (rarely) associated with germline succinate dehydrogenase defects

scientific article published on 15 July 2015

Carney triad, SDH-deficient tumors, and Sdhb+/- mice share abnormal mitochondria

scientific article published on 25 March 2015

Catecholamine metabolomic and secretory phenotypes in phaeochromocytoma ⬇️

scientific article published on December 21, 2010

Catecholamine-Induced Cardiomyopathy in Pheochromocytoma: How to Manage a Rare Complication in a Rare Disease?

scientific article published on 18 September 2018

Central nervous system imprinting of the G protein G(s)alpha and its role in metabolic regulation

scientific article published on June 2009

Cerebrospinal Fluid Catecholamine Levels as Predictors of Outcome in Subarachnoid Hemorrhage ⬇️

scientific article published on January 5, 2012

Changes of noradrenergic activity and lipolysis in the subcutaneous abdominal adipose tissue of hypo- and hyperthyroid patients: an in vivo microdialysis study

scientific article published in June 2004

Characteristics of Pediatric vs Adult Pheochromocytomas and Paragangliomas

scientific article

Characterization of an animal model of aggressive metastatic pheochromocytoma linked to a specific gene signature

scientific article

Characterization of two mouse models of metastatic pheochromocytoma using bioluminescence imaging ⬇️

scientific article published on October 20, 2011

Choice of biochemical test for diagnosis of pheochromocytoma: validation of plasma metanephrines

scientific article

Chronic hypercortisolemia inhibits dopamine synthesis and turnover in the nucleus accumbens: an in vivo microdialysis study

scientific article published in September 2002

Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD.

scientific article

Clinical characteristics and outcomes of SDHB-related pheochromocytoma and paraganglioma in children and adolescents

scientific article published on 15 February 2020

Clinical review: Current treatment of malignant pheochromocytoma

scientific article published on 6 February 2007

Clinical, Diagnostic, and Treatment Characteristics of -Related Metastatic Pheochromocytoma and Paraganglioma

Combined Inhibition of mTORC1 and mTORC2 Signaling Pathways Is a Promising Therapeutic Option in Inhibiting Pheochromocytoma Tumor Growth: In Vitro and In Vivo Studies in Female Athymic Nude Mice ⬇️

scientific article published on January 10, 2013

Combined blockade of signalling pathways shows marked anti-tumour potential in phaeochromocytoma cell lines

scientific article

Comparison of 18F-fluoro-L-DOPA, 18F-fluoro-deoxyglucose, and 18F-fluorodopamine PET and 123I-MIBG scintigraphy in the localization of pheochromocytoma and paraganglioma

scientific article published on 28 October 2009

Comparison of 6-18F-fluorodopamine PET with 123I-metaiodobenzylguanidine and 111in-pentetreotide scintigraphy in localization of nonmetastatic and metastatic pheochromocytoma

scientific article published on 15 September 2008

Comparison of clinical and imaging features in succinate dehydrogenase-positive versus sporadic paragangliomas

scientific article published on December 2011

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

scientific article

Comprehensive review of evaluation and management of cardiac paragangliomas

scientific article published on 22 May 2020

Continued Tumor Reduction of Metastatic Pheochromocytoma/Paraganglioma Harboring Succinate Dehydrogenase Subunit B Mutations with Cyclical Chemotherapy

scientific article published on 5 April 2018

Correlation between in vivo 18F-FDG PET and immunohistochemical markers of glucose uptake and metabolism in pheochromocytoma and paraganglioma

scientific article published on 12 June 2014

Corrigendum: Landscape of the mitochondrial Hsp90 metabolome in tumours

scientific article published on 18 June 2015

Counseling patients with succinate dehydrogenase subunit defects: genetics, preventive guidelines, and dealing with uncertainty

scientific article

Current Role of Metaiodobenzylguanidine in the Diagnosis of Pheochromocytoma and Medullary Thyroid Cancer ⬇️

scientific article published on September 1, 2011

Current and future trends in the anatomical and functional imaging of head and neck paragangliomas

scientific article

Current approaches and recent developments in the management of head and neck paragangliomas

scientific article

Current approaches and recommended algorithm for the diagnostic localization of pheochromocytoma

scientific article published on February 2004

Current views on cell metabolism in SDHx-related pheochromocytoma and paraganglioma

scientific article

Cushing's syndrome due to ectopic corticotropin secretion: twenty years' experience at the National Institutes of Health

scientific article published on 24 May 2005

Cytocidal activities of topoisomerase 1 inhibitors and 5-azacytidine against pheochromocytoma/paraganglioma cells in primary human tumor cultures and mouse cell lines

scientific article (publication date: 2014)

Deletion of the von Hippel-Lindau gene in hemangioblasts causes hemangioblastoma-like lesions in murine retina

scientific article published on 4 January 2018

Determinants of Central Sympathetic Activation in Spontaneous Primary Subarachnoid Hemorrhage ⬇️

scientific article published on June 1, 2012

Determination of the unmetabolised (18)F-FDG fraction by using an extension of simplified kinetic analysis method: clinical evaluation in paragangliomas

scientific article published on 5 June 2015

Development and validation of a comprehensive mutation and deletion detection assay for SDHB, SDHC, and SDHD

scientific article

Diagnosis and localization of pheochromocytoma

scientific article published on 15 March 2004

Diagnosis and preoperative imaging of multiple endocrine neoplasia type 2: current status and future directions

scientific article published on 28 June 2014

Diagnostic Investigation of Lesions Associated with Succinate Dehydrogenase Defects

scientific article published on 4 April 2018

Diagnostic imaging of pheochromocytoma

scientific article published on January 2004

Diagnostic localization of malignant bladder pheochromocytoma using 6-18F fluorodopamine positron emission tomography

scientific article published in January 2003

Diagnostic localization of pheochromocytoma: the coming of age of positron emission tomography

scientific article

Different expression of catecholamine transporters in phaeochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2.

scientific article published on October 2005

Differential expression of erythropoietin and its receptor in von hippel-lindau-associated and multiple endocrine neoplasia type 2-associated pheochromocytomas

scientific article

Differential expression of the regulated catecholamine secretory pathway in different hereditary forms of pheochromocytoma

scientific article published on 14 October 2008

Discordant localization of 2-[18F]-fluoro-2-deoxy-D-glucose in 6-[18F]-fluorodopamine- and [(123)I]-metaiodobenzylguanidine-negative metastatic pheochromocytoma sites

scientific article

Documenting stress in caregivers of transplantation patients: initial evidence of HPA dysregulation

scientific article published on 07 March 2016

Double stable isotope ultra performance liquid chromatographic-tandem mass spectrometric quantification of tissue content and activity of phenylethanolamine N-methyltransferase, the crucial enzyme responsible for synthesis of epinephrine ⬇️

scientific article published on December 8, 2012

Double-barreled gun: Combination of PARP inhibitor with conventional chemotherapy

scientific article published on 2 April 2018

Downregulation of metastasis suppressor genes in malignant pheochromocytoma.

scientific article published in March 2005

Drugs and pheochromocytoma--don't be fooled by every elevated metanephrine

scientific article

EANM 2012 guidelines for radionuclide imaging of phaeochromocytoma and paraganglioma

scientific article

Ectopic Cushing's syndrome caused by an esthesioneuroblastoma

scientific article published in March 2004

Effects of hypo- and hyperthyroidism on noradrenergic activity and glycerol concentrations in human subcutaneous abdominal adipose tissue assessed with microdialysis

scientific article published in December 2003

Emergencies caused by pheochromocytoma, neuroblastoma, or ganglioneuroma

scientific article

Emerging role of dopamine in neovascularization of pheochromocytoma and paraganglioma

scientific article published on 6 March 2017

Endocrine regulation of subcutaneous fat metabolism during cold exposure in humans.

scientific article

Endocrine tumors associated with the vagus nerve

scientific article

Endocrine withdrawal syndromes

scientific article

Epinephrine deficiency results in intact glucose counter-regulation, severe hepatic steatosis and possible defective autophagy in fasting mice ⬇️

scientific article published on March 3, 2012

ErbB-2 induces bilateral adrenal pheochromocytoma formation in mice

scientific article published on 31 May 2007

Exercise-induced nausea and vomiting: another sign and symptom of pheochromocytoma and paraganglioma ⬇️

scientific article published on April 21, 2010

Expression of the noradrenaline transporter and phenylethanolamine N-methyltransferase in normal human adrenal gland and phaeochromocytoma

scientific article published on 27 July 2005

Extent and Determinants of Thermogenic Responses to 24 Hours of Fasting, Energy Balance, and Five Different Overfeeding Diets in Humans ⬇️

scientific article published on May 10, 2013

External beam radiation therapy in treatment of malignant pheochromocytoma and paraganglioma

scientific article

False-negative 123I-MIBG SPECT is most commonly found in SDHB-related pheochromocytoma or paraganglioma with high frequency to develop metastatic disease ⬇️

scientific article published on February 13, 2012

Familial pheochromocytomas and paragangliomas ⬇️

scientific article published on 07 August 2013

Functional Imaging Signature of Patients Presenting with Polycythemia/Paraganglioma Syndromes

scientific article published on 23 March 2017

Functional and Oncologic Outcomes of Partial Adrenalectomy for Pheochromocytoma in Patients With von Hippel-Lindau Syndrome After at Least 5 Years of Followup ⬇️

scientific article published on September 17, 2010

Functional characterization of nonmetastatic paraganglioma and pheochromocytoma by 18F‐FDOPA PET: focus on missed lesions ⬇️

scientific article published on May 6, 2013

Functional imaging of SDHx-related head and neck paragangliomas: comparison of 18F-fluorodihydroxyphenylalanine, 18F-fluorodopamine, 18F-fluoro-2-deoxy-D-glucose PET, 123I-metaiodobenzylguanidine scintigraphy, and 111In-pentetreotide scintigraphy

scientific article

Functional imaging of endocrine tumors: role of positron emission tomography

scientific article published in August 2004

Gender-related differences in the clinical presentation of malignant and benign pheochromocytoma

scientific article

Gene expression profiling of benign and malignant pheochromocytoma

scientific article published on August 2006

Genetic Testing for Pheochromocytoma ⬇️

scientific article published on December 1, 2010

Genetics of pheochromocytoma and paraganglioma syndromes: new advances and future treatment options

scientific article

Genetics, diagnosis, and management of medullary thyroid carcinoma and pheochromocytoma/paraganglioma

scientific article published on February 2014

Genomic Landscape of Pheochromocytoma and Paraganglioma

scientific article published on 26 November 2017

Genomic imprinting at a boundary element flanking the SDHD locus ⬇️

scientific article published on August 23, 2011

Genomic medicine: exploring the basis of a new approach to endocrine hypertension

scientific article

Genotype and tumor locus determine expression profile of pseudohypoxic pheochromocytomas and paragangliomas

scientific article published on April 2013

Glucocorticoid treatment--effect on adrenal medullary catecholamine production

scientific article

HIF-2alpha: Achilles' heel of pseudohypoxic subtype paraganglioma and other related conditions

scientific article published on 22 September 2017

High frequency of SDHB germline mutations in patients with malignant catecholamine-producing paragangliomas: implications for genetic testing

scientific article

High-throughput screening for the identification of new therapeutic options for metastatic pheochromocytoma and paraganglioma

scientific article

Histone deacetylase inhibitors increase glucocerebrosidase activity in Gaucher disease by modulation of molecular chaperones ⬇️

scientific article published on December 31, 2012

Hypertension in pheochromocytoma: characteristics and treatment

scientific article

Hypotension in a Woman with a Metastatic Dopamine-Secreting Carotid Body Tumor ⬇️

scientific article published on July 1, 2003

Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models

scientific article published on 26 May 2016

Hypoxia-Inducible Factor 2α Mutation-Related Paragangliomas Classify as Discrete Pseudohypoxic Subcluster

scientific article published on September 2016

Hypoxia-Inducible Factor Signaling in Pheochromocytoma: Turning the Rudder in the Right Direction ⬇️

scientific article published on August 12, 2013

In vivo micro-CT imaging of liver lesions in small animal models

scientific article

Increased uptake of [¹²³I]meta-iodobenzylguanidine, [¹⁸F]fluorodopamine, and [³H]norepinephrine in mouse pheochromocytoma cells and tumors after treatment with the histone deacetylase inhibitors

scientific article

Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects

scientific article

Integrated whole-body PET/MRI with 18F-FDG, 18F-FDOPA, and 18F-FDA in paragangliomas in comparison with PET/CT: NIH first clinical experience with a single-injection, dual-modality imaging protocol

scientific article

Introduction: Endocrine cancers.

scientific article

Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans

scientific article

Ivabradine in Catecholamine-Induced Tachycardia in a Patient with Paraganglioma.

scientific article

Krebs cycle metabolite profiling for identification and stratification of pheochromocytomas/paragangliomas due to succinate dehydrogenase deficiency

scientific article

Landscape of the mitochondrial Hsp90 metabolome in tumours ⬇️

scientific article published on January 1, 2013

Laparoscopic management of extra-adrenal pheochromocytoma

scientific article

Leptomeningeal dissemination of a low-grade lumbar paraganglioma: case report

scientific article published on 27 January 2017

Local sympathetic function in human skeletal muscle and adipose tissue assessed by microdialysis

scientific article published in February 2002

Localization of medullary thyroid carcinoma metastasis in a multiple endocrine neoplasia type 2A patient by 6-[18F]-fluorodopamine positron emission tomography

scientific article

Long intergenic noncoding RNA profiles of pheochromocytoma and paraganglioma: A novel prognostic biomarker

scientific article published on 11 October 2019

Loss of meal-induced decrease in plasma ghrelin levels in patients with anorexia nervosa

scientific article published in April 2003

Low sensitivity of glucagon provocative testing for diagnosis of pheochromocytoma

scientific article

MAX Mutations Cause Hereditary and Sporadic Pheochromocytoma and Paraganglioma

scientific article published on 27 March 2012

Magnetic resonance spectroscopy of paragangliomas: new insights into in vivo metabolomics

scientific article

Malignant paraganglioma associated with succinate dehydrogenase subunit B in an 8-year-old child: the age of first screening?

scientific article

Malignant pheochromocytoma: current status and initiatives for future progress

scientific article

Mass spectrometric quantification of salivary metanephrines-A study in healthy subjects

scientific article published on 10 February 2016

Mathematical modeling of disease dynamics in SDHB- and SDHD-related paraganglioma: Further step in understanding hereditary tumor differences and future therapeutic strategies

scientific article published in PLoS ONE

Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma

scientific article

Mechanisms of enhanced beta-adrenergic reserve from cardiac resynchronization therapy

scientific article

Mediastinal paragangliomas: association with mutations in the succinate dehydrogenase genes and aggressive behavior

scientific article

Metabolome profiling by HRMAS NMR spectroscopy of pheochromocytomas and paragangliomas detects SDH deficiency: clinical and pathophysiological implications

scientific article

Metastasis-associated gene expression profile of liver and subcutaneous lesions derived from mouse pheochromocytoma cells

scientific article published on April 2008

Metastatic Phaeochromocytoma: Spinning Towards More Promising Treatment Options

scientific article published on 20 September 2018

Metastatic paraganglioma

scientific article

Metastatic pheochromocytoma/paraganglioma related to primary tumor development in childhood or adolescence: significant link to SDHB mutations

scientific article published on 3 October 2011

MicroCT for high-resolution imaging of ectopic pheochromocytoma tumors in the liver of nude mice

scientific article published on November 2006

Minimal changes in environmental temperature result in a significant increase in energy expenditure and changes in the hormonal homeostasis in healthy adults

scientific article

Missense mutations in the human SDHB gene increase protein degradation without altering intrinsic enzymatic function ⬇️

scientific article published on July 26, 2012

Mitochondrial Complex II: At the Crossroads

scientific article published on 6 February 2017

Mitochondrial localization of human recombinant adenovirus: from evolution to gene therapy

scientific article published on January 2007

Molecular Subtypes of KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Gastrointestinal Stromal Tumor Clinic

scientific article

Molecular imaging and theranostic approaches in pheochromocytoma and paraganglioma

scientific article published on 15 February 2018

Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload

scientific article

Monoamine oxidase B prompts mitochondrial and cardiac dysfunction in pressure overloaded hearts

scientific article

Multidisciplinary management of locally advanced and widely metastatic paraganglioma in a patient with life-threatening compressive symptoms

scientific article published on 20 April 2015

Multitracer PET imaging of bone metastases from paraganglioma: peripheral halo of uptake on 18F-FLT PET mismatching with central uptake of 18F-FDOPA, 18F-fluorodopamine, and 18F-FDG ⬇️

scientific article published on July 24, 2013

Murine models and cell lines for the investigation of pheochromocytoma: applications for future therapies?

scientific article

Mutation-targeted therapy with sunitinib or everolimus in patients with advanced low-grade or intermediate-grade neuroendocrine tumours of the gastrointestinal tract and pancreas with or without cytoreductive surgery: protocol for a phase II clinica

scientific article published on 19 May 2015

Mutations associated with succinate dehydrogenase D-related malignant paragangliomas

scientific article published on 31 October 2007

NF‐κB inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model ⬇️

scientific article published on August 20, 2012

Neuropeptide Y expression in phaeochromocytomas: relative absence in tumours from patients with von Hippel-Lindau syndrome

scientific article published on May 2007

New Insights into the Nuclear Imaging Phenotypes of Cluster 1 Pheochromocytoma and Paraganglioma

scientific article published on 31 August 2017

New Perspectives on Pheochromocytoma and Paraganglioma: Toward a Molecular Classification

scientific article published on 4 August 2017

New Roles of Carboxypeptidase E in Endocrine and Neural Function and Cancer ⬇️

scientific article published on March 7, 2012

New advances in the biochemical diagnosis of pheochromocytoma: moving beyond catecholamines

scientific article

New challenges in nuclear endocrinology

scientific article published on 9 November 2017

New functional imaging modalities for chromaffin tumors, neuroblastomas and ganglioneuromas

scientific article

New imaging approaches to phaeochromocytomas and paragangliomas

scientific article

New insights into the genetics of familial chromaffin cell tumors

scientific article

New insights on the pathogenesis of paraganglioma and pheochromocytoma

New syndrome of paraganglioma and somatostatinoma associated with polycythemia

scientific article published on 18 March 2013

Noninvasive monitoring of a murine model of metastatic pheochromocytoma: a comparison of contrast-enhanced microCT and nonenhanced MRI.

scientific article published on March 2009

Nonmosaic somatic HIF2A mutations associated with late onset polycythemia-paraganglioma syndrome: Newly recognized subclass of polycythemia-paraganglioma syndrome

scientific article published on 15 January 2019

Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas ⬇️

scientific article published on January 29, 2013

Novel insights into the polycythemia-paraganglioma-somatostatinoma syndrome

scientific article

OR29-6 Brown Adipose Tissue Activation in SDHx-Related Pheochromocytoma and Paraganglioma: An Ominous Sign?

scientific article

Ocular manifestations of hypoxia-inducible factor-2α paraganglioma-somatostatinoma-polycythemia syndrome

scientific article

Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X.

scientific article published on 7 April 2014

Overexpression of interleukin-13 receptor-alpha2 in neuroendocrine malignant pheochromocytoma: a novel target for receptor directed anti-cancer therapy

scientific article published on 02 June 2009

PET Imaging for Endocrine Malignancies: From Woe to Go

article published in 2017

PET Scans With 18F-Fluorodeoxyglucose to Diagnose Adrenal Tumors-Reply

scientific article published in October 2017

PET/CT comparing (68)Ga-DOTATATE and other radiopharmaceuticals and in comparison with CT/MRI for the localization of sporadic metastatic pheochromocytoma and paraganglioma

scientific article

PRECISION MEDICINE IN ADRENAL DISORDERS: THE NEXT GENERATION.

scientific article published on 23 March 2017

PRECISION MEDICINE: AN UPDATE ON GENOTYPE/BIOCHEMICAL PHENOTYPE RELATIONSHIPS IN PHEOCHROMOCYTOMA/PARAGANGLIOMA PATIENTS.

scientific article published on 23 March 2017

Paraganglioma of the organ of Zuckerkandl associated with a somatic HIF2α mutation: A case report

scientific article

Partial adrenalectomy: underused first line therapy for small adrenal tumors

scientific article

Pathology of Human Pheochromocytoma and Paraganglioma Xenografts in NSG Mice

scientific article published on 06 October 2016

Pediatric patients with pheochromocytoma and paraganglioma should have routine preoperative genetic testing for common susceptibility genes in addition to imaging to detect extra-adrenal and metastatic tumors

scientific article published on 16 November 2016

Phaeochromocytoma

scientific article

Pharmacologic Modulation of Serine/Threonine Phosphorylation Highly Sensitizes PHEO in a MPC Cell and Mouse Model to Conventional Chemotherapy ⬇️

scientific article published on February 14, 2011

PheoSeq: A Targeted Next-Generation Sequencing Assay for Pheochromocytoma and Paraganglioma Diagnostics

scientific article published on 25 May 2017

Pheochromocytoma

scientific article

Pheochromocytoma Screening Initiation and Frequency in von Hippel-Lindau Syndrome

scientific article

Pheochromocytoma and Paraganglioma: Current Functional and Future Molecular Imaging ⬇️

scientific article published on January 6, 2012

Pheochromocytoma and paraganglioma

scientific article

Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline

scientific article published in June 2014

Pheochromocytoma and paraganglioma: diagnosis, genetics, management, and treatment

scientific article

Pheochromocytoma as an endocrine emergency

scientific article

Pheochromocytoma catecholamine phenotypes and prediction of tumor size and location by use of plasma free metanephrines

scientific article

Pheochromocytoma crisis induced by glucocorticoids: a report of four cases and review of the literature

scientific article published on March 2008

Pheochromocytoma: Gasping for Air.

scientific article published on 03 July 2015

Pheochromocytoma: The First Metabolic Endocrine Cancer

scientific article

Pheochromocytoma: an endocrine stress mimicking disorder

scientific article

Pheochromocytoma: recommendations for clinical practice from the First International Symposium. October 2005.

scientific article published on February 2007

Phosphoprotein-based biomarkers as predictors for cancer therapy

scientific article published on 20 July 2020

Phospho‐mTOR is not upregulated in metastatic SDHB paragangliomas ⬇️

scientific article published on July 26, 2013

Plasma metanephrines in renal failure

scientific article published in February 2005

Plasma methoxytyramine: A novel biomarker of metastatic pheochromocytoma and paraganglioma in relation to established risk factors of tumour size, location and SDHB mutation status ⬇️

scientific article published on October 28, 2011

Plasma‐free vs deconjugated metanephrines for diagnosis of phaeochromocytoma ⬇️

scientific article published on April 17, 2013

Potential therapeutic target for malignant paragangliomas: ATP synthase on the surface of paraganglioma cells

scientific article published on 15 March 2015

Prediction of the location and size of the stomach using patient characteristics for retrospective radiation dose estimation following radiotherapy

scientific article

Preoperative 18F-FDG PET/CT in Pheochromocytomas and Paragangliomas Allows for Precision Surgery

scientific article published on 12 January 2018

Preoperative Imaging Features are Associated with Surgical Complications Following Carotid Body Tumor Resection

scientific article published in August 2015

Preoperative management of the pheochromocytoma patient

scientific article

Prospective Study of 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography for Detecting Gastro-Entero-Pancreatic Neuroendocrine Tumors and Unknown Primary Sites

scientific article published on 28 December 2015

Prospective comparison of (68)Ga-DOTATATE and (18)F-FDOPA PET/CT in patients with various pheochromocytomas and paragangliomas with emphasis on sporadic cases

scientific article published on 5 December 2015

Proteomic profiling of von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2 pheochromocytomas reveals different expression of chromogranin B.

scientific article published in June 2007

Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas ⬇️

scientific article published on February 2014

RNA-Sequencing Analysis of Adrenocortical Carcinoma, Pheochromocytoma and Paraganglioma from a Pan-Cancer Perspective

Radiofrequency ablation of metastatic pheochromocytoma

scientific article published on November 2009

Radiopharmaceuticals in paraganglioma imaging: too many members on board?

scientific article published on 13 October 2015

Rapidly Growing Chest Wall Mass in a Case of Sporadic Metastatic Paraganglioma: Imaging With 4 Different PET Radiopharmaceuticals

scientific article published on 30 January 2016

Recurrent somatic mutations of PRKAR1A in isolated cardiac myxoma

scientific article published on 19 October 2017

Reference intervals for plasma free metanephrines with an age adjustment for normetanephrine for optimized laboratory testing of phaeochromocytoma

scientific article

Relevant Discordance Between 68Ga-DOTATATE and 68Ga-DOTANOC in SDHB-Related Metastatic Paraganglioma: Is Affinity to Somatostatin Receptor 2 the Key?

scientific article

Renaissance of (18)F-FDG positron emission tomography in the imaging of pheochromocytoma/paraganglioma

scientific article

Reply: 68Ga-DOTATATE PET/CT Versus MRI: Why the Comparison of 68Ga-DOTATATE PET/CT to an Appropriate MRI Protocol Is Essential

scientific article published on 4 August 2016

Response after Surgical Resection of Metastatic Pheochromocytoma and Paraganglioma: Can Postoperative Biochemical Remission Be Predicted? ⬇️

scientific article published on July 25, 2013

Results of (68)Gallium-DOTATATE PET/CT Scanning in Patients with Multiple Endocrine Neoplasia Type 1.

scientific article published on 20 April 2015

Role of hypoxia and HIF2α in development of the sympathoadrenal cell lineage and chromaffin cell tumors with distinct catecholamine phenotypic features

scientific article published on January 2013

SDH-related pheochromocytoma and paraganglioma ⬇️

scientific article published on June 1, 2010

SDHB mutation status and tumor size but not tumor grade are important predictors of clinical outcome in pheochromocytoma and abdominal paraganglioma

scientific article published on 10 November 2016

SDHB-related pheochromocytoma and paraganglioma penetrance and genotype-phenotype correlations

scientific article

SDHB/SDHA immunohistochemistry in pheochromocytomas and paragangliomas: a multicenter interobserver variation analysis using virtual microscopy: a Multinational Study of the European Network for the Study of Adrenal Tumors (ENS@T).

scientific article published on 27 February 2015

SUN-330 Non-Mosaic Somatic HIF2A Mutations Associated with Late-Onset Polycythemia-Paraganglioma Syndrome: Newly Recognized Subclass of Polycythemia-Paraganglioma Syndrome.

scientific article

SUN-333 Expression of Type 2 Somatostatin Receptors and Low Tumor Markers of Aggressiveness Correlate with Positive 68Ga-DOTATATE Findings in Ectopic ACTH-Producing Tumors.

scientific article published on 30 April 2019

Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes

scientific article published in February 2018

Somatic HIF2A gain-of-function mutations in paraganglioma with polycythemia

scientific article

Somatic VHL gene alterations in MEN2-associated medullary thyroid carcinoma

scientific article published on 17 May 2006

Somatic gain-of-function HIF2A mutations in sporadic central nervous system hemangioblastomas

scientific article published on 29 October 2015

Somatic mosaicism of EPAS1 mutations in the syndrome of paraganglioma and somatostatinoma associated with polycythemia

scientific article published on 10 December 2015

Somatostatin receptor expression on von Hippel-Lindau-associated hemangioblastomas offers novel therapeutic target

scientific article

Staging and functional characterization of pheochromocytoma and paraganglioma by 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography

scientific article published on 18 April 2012

Stress-induced alterations in catecholamine enzymes gene expression in the hypothalamic dorsomedial nucleus are modulated by caudal brain and not hypothalamic paraventricular nucleus neurons

scientific journal article

Subclinical phaeochromocytoma

scientific article

Successful Second-Line Metronomic Temozolomide in Metastatic Paraganglioma: Case Reports and Review of the Literature.

scientific article

Succinate Dehydrogenase Kidney Cancer: An Aggressive Example of the Warburg Effect in Cancer ⬇️

scientific article (publication date: December 2012)

Succinate dehydrogenase (SDH) D subunit (SDHD) inactivation in a growth-hormone-producing pituitary tumor: a new association for SDH?

scientific article published on 14 December 2011

Succinate dehydrogenase gene mutations are strongly associated with paraganglioma of the organ of Zuckerkandl

scientific article

Succinate dehydrogenase gene mutations in cardiac paragangliomas

scientific article published on 24 March 2015

Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor

scientific article

Succinate-to-fumarate ratio as a new metabolic marker to detect the presence of SDHB/D-related paraganglioma: initial experimental and ex vivo findings

scientific article

Superiority of 6-[18F]-fluorodopamine positron emission tomography versus [131I]-metaiodobenzylguanidine scintigraphy in the localization of metastatic pheochromocytoma

scientific article published on September 2003

Superiority of 68Ga-DOTATATE over 18F-FDG and anatomic imaging in the detection of succinate dehydrogenase mutation (SDHx )-related pheochromocytoma and paraganglioma in the pediatric population.

scientific article published on 4 December 2017

Superiority of [68Ga]-DOTATATE PET/CT to Other Functional Imaging Modalities in the Localization of SDHB-Associated Metastatic Pheochromocytoma and Paraganglioma

scientific article

Surgical Management of Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Pediatric and Wildtype GIST Clinic

scientific article published on 28 December 2016

Sympathoadrenal function in patients with paroxysmal hypertension: pseudopheochromocytoma

scientific article published in November 2007

Targeting Heat Shock Protein 90 for the Treatment of Malignant Pheochromocytoma ⬇️

scientific article published on February 14, 2013

The Author's Reply: inappropriate adrenoreceptor blockade prior to pheochromocytoma removal - 'A timely reappraisal'.

scientific article published on 13 September 2016

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer

scientific article

The adrenal medulla and extra-adrenal paraganglia: then and now.

scientific article

The effects of carbidopa on uptake of 6-18F-Fluoro-L-DOPA in PET of pheochromocytoma and extraadrenal abdominal paraganglioma

scientific article

The genetic basis of pheochromocytoma and paraganglioma: implications for management

scientific article

The incidentally discovered adrenal mass

The molecular pathogenesis of hereditary and sporadic adrenocortical and adrenomedullary tumors

scientific article

The optimal imaging of adrenal tumours: a comparison of different methods

scientific article published on September 2007

The role of [(18)F]fluorodeoxyglucose positron emission tomography and [(111)In]-diethylenetriaminepentaacetate-D-Phe-pentetreotide scintigraphy in the localization of ectopic adrenocorticotropin-secreting tumors causing Cushing's syndrome

scientific article

The size of the primary tumor and age at initial diagnosis are independent predictors of the metastatic behavior and survival of patients with SDHB-related pheochromocytoma and paraganglioma: a retrospective cohort study

scientific article

The use of functional imaging in a patient with head and neck paragangliomas

scientific article

Treatment of malignant pheochromocytoma/paraganglioma with cyclophosphamide, vincristine, and dacarbazine: recommendation from a 22-year follow-up of 18 patients

scientific article

Tyrosine hydroxylase, chromogranin A, and steroidogenic acute regulator as markers for successful separation of human adrenal medulla

scientific article

Unexplained symptomatic paroxysmal hypertension in pseudopheochromocytoma: a stress response disorder?

scientific article

Update of Pheochromocytoma Syndromes: Genetics, Biochemical Evaluation, and Imaging

article

Update on pediatric pheochromocytoma

scientific article published on 20 June 2008

Urinary Bladder Paragangliomas: How Immunohistochemistry Can Assist to Identify Patients With SDHB Germline and Somatic Mutations

scientific article

Use of 6-[18F]-fluorodopamine positron emission tomography (PET) as first-line investigation for the diagnosis and localization of non-metastatic and metastatic phaeochromocytoma (PHEO).

scientific article published on 05 December 2008

Usefulness of 123I-MIBG scintigraphy in the evaluation of patients with known or suspected primary or metastatic pheochromocytoma or paraganglioma: results from a prospective multicenter trial

scientific article

Usefulness of [18F]-DA and [18F]-DOPA for PET imaging in a mouse model of pheochromocytoma ⬇️

scientific article published on September 29, 2011

Usefulness of standardized uptake values for distinguishing adrenal glands with pheochromocytoma from normal adrenal glands by use of 6-18F-fluorodopamine PET.

scientific article published on 15 November 2007

Utility of plasma free metanephrines for detecting childhood pheochromocytoma

scientific article

Utility of plasma free metanephrines in diagnosis of factitious pheochromocytoma

scientific article published on September 2006

WHY TAKE THE RISK? WE ONLY LIVE ONCE - THE DANGERS ASSOCIATED WITH NEGLECTING A PREOPERATIVE ALPHA ADRENOCEPTOR BLOCKADE IN PHEOCHROMOCYTOMA PATIENTS

scientific article published on 5 October 2018

Warburg effect's manifestation in aggressive pheochromocytomas and paragangliomas: insights from a mouse cell model applied to human tumor tissue

scientific article

When is a phaeo not a phaeo? Depression in an adolescent leading to a phaeochromocytoma‐like biochemical profile ⬇️

scientific article published on October 1, 2011

ZNF367 inhibits cancer progression and is targeted by miR-195

scientific article

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