List of works - Annemarie Poustka

A 15q13.3 microdeletion segregating with autism

scientific article

A compendium to ensure computational reproducibility in high-dimensional classification tasks

scientific article published on 19 December 2004

A gene for FG syndrome maps in the Xq12-q21.31 region

article

A genome-wide scan for common alleles affecting risk for autism

scientific journal article

A microscope-based screening platform for large-scale functional protein analysis in intact cells

scientific article published in November 2003

A mutation hot spot for nonspecific X-linked mental retardation in the MECP2 gene causes the PPM-X syndrome

scientific article published on 15 February 2002

A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder

scientific article published on 14 October 2011

A physical map of the human genome

scientific article

Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma

scientific article

Alternative pre-mRNA processing regulates cell-type specific expression of the IL4l1 and NUP62 genes

scientific article

An anthropoid-specific segmental duplication on human chromosome 1q22.

scientific article

Analysis of genetic variations of protein tyrosine kinase fyn and their association with alcohol dependence in two independent cohorts

scientific article published in December 2003

Analysis of pigmented villonodular synovitis with genome-wide complementary DNA microarray and tissue array technology reveals insight into potential novel therapeutic approaches.

scholarly article

Animal models of autism

scholarly article by Sabine M. Klauck & Annemarie Poustka published December 2006 in Drug discovery today. Disease models

Antibody microarrays as an experimental platform for the analysis of signal transduction networks

scientific article published on January 2008

Association studies of the HOPA dodecamer duplication variant in different subtypes of autism

scientific article (publication date: 8 January 2002)

Automated production of recombinant human proteins as resource for proteome research

scientific article

Basal transcription activity of the dyskeratosis congenita gene is mediated by Sp1 and Sp3 and a patient mutation in a Sp1 binding site is associated with decreased promoter activity

scientific article

CDNAs for functional genomics and proteomics: the German Consortium

scientific article published on October 2003

CRP-ductin, the mouse homologue of gp-340/deleted in malignant brain tumors 1 (DMBT1), binds gram-positive and gram-negative bacteria and interacts with lung surfactant protein D

scientific article

Candidate genes for cross-resistance against DNA-damaging drugs.

scientific article published on November 2002

Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis

scientific article

Combinatorial RNAi for quantitative protein network analysis

scholarly article

Combinatorial synthesis of peptide arrays with a laser printer

scientific article

Contact spotting of protein microarrays coupled with spike-in of normalizer protein permits time-resolved analysis of ERBB receptor signaling

scientific article

DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease

scientific article published on 3 August 2007

DMBT1 expression distinguishes anorectal from cutaneous melanoma

scientific article published in January 2009

DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands

scientific article

DMBT1 is frequently downregulated in well-differentiated gastric carcinoma but more frequently upregulated across various gastric cancer types

scientific article

Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant

scientific article

Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer

scientific article

Direct pulsed field gel electrophoresis of Wilms' tumors shows that dna deletions in 11 p 13 are rare

scientific article published on 01 March 1991

Down-regulation of HLA Class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells.

scientific article published in October 2009

Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer

scientific article

Estimating large-scale signaling networks through nested effect models with intervention effects from microarray data

scientific article

Exclusion of mutations in the MTMR1 gene as a frequent cause of X-linked myotubular myopathy

scientific article published in January 2002

Expression of acyl-CoA synthetase 5 reflects the state of villus architecture in human small intestine

scientific article published in February 2004

Expression of deleted in malignant brain tumor-1 (DMBT1) molecule in biliary epithelium is augmented in hepatolithiasis: possible participation in lithogenesis

scientific article published in July 2003

Extending pathways based on gene lists using InterPro domain signatures

scientific article

Extraction and processing of high quality RNA from impalpable and macroscopically invisible prostate cancer for microarray gene expression analysis

scientific article published in September 2005

FARP2, HDLBP and PASK are downregulated in a patient with autism and 2q37.3 deletion syndrome

scholarly article by Bärbel Felder et al published 13 April 2009 in American Journal of Medical Genetics

Filamin (FLN1),plexin (SEX), major palmitoylated proteinp55 (MPP1), and von-Hippel Lindau binding protein (VBP1) are not involved in incontinentia pigmenti type 2

scientific article published on 01 September 2000

Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer.

scientific article published on June 2003

From ORFeome to biology: a functional genomics pipeline

scientific article

Functional impact of global rare copy number variation in autism spectrum disorders

scientific article published on 15 July 2010

Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle

scientific article

GOSim--an R-package for computation of information theoretic GO similarities between terms and gene products

scientific article

Gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking

scientific article

Gene expression analysis of endobronchial epithelial lining fluid in the evaluation of indeterminate pulmonary nodules.

scientific article

Generation of a vector system facilitating cloning of DMBT1 variants and recombinant expression of functional full-length DMBT1.

scientific article

Genetic mapping in mice identifies DMBT1 as a candidate modifier of mammary tumors and breast cancer risk

scientific article

Genetic variation of Aflatoxin B1 aldehyde reductase genes (AFAR) in human tumour cells

scientific article

Genomic analysis reveals poor separation of human cardiomyopathies of ischemic and nonischemic etiologies

scientific article published on 22 April 2008

Global gene expression analysis reveals specific patterns of cell junctions in non-small cell lung cancer subtypes.

scientific article published on 16 May 2008

Haplotype analysis of the COMT-ARVCF gene region in Israeli anorexia nervosa family trios

scientific article

High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic

scientific article

High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins

scientific article published on 3 May 2007

Human homologue of the murinebare patches/striated gene is not mutated in incontinentia pigmenti type 2

article

Identification and meta-analysis of a small gene expression signature for the diagnosis of estrogen receptor status in invasive ductal breast cancer

scientific article published on December 2006

Identification of a common gene expression signature in dilated cardiomyopathy across independent microarray studies

scientific article published on 27 September 2006

Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancer

scientific article published on 28 June 2007

Identification of cellular targets for the human papillomavirus E6 and E7 oncogenes by RNA interference and transcriptome analyses

scientific article

Identification of the bacteria-binding peptide domain on salivary agglutinin (gp-340/DMBT1), a member of the scavenger receptor cysteine-rich superfamily

scientific article

Infrared-based protein detection arrays for quantitative proteomics

scientific article published on February 2007

Integrative annotation of 21,037 human genes validated by full-length cDNA clones

scientific article

LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system

scientific article

Large scale statistical inference of signaling pathways from RNAi and microarray data

scientific article

Large-scale protein expression for proteome research

scientific article published in September 2005

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

scientific article

Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance

scientific article

Modeling breast cell cycle regulation--overcoming drug resistance

scientific article

Molecular cancer phenotype in normal prostate tissue

scientific article

Molecular characterization of the porcine deleted in malignant brain tumors 1 gene (DMBT1).

scientific article published on 20 March 2006

Multiplex reverse transcription-polymerase chain reaction combined with on-chip electrophoresis as a rapid screening tool for candidate gene sets

scientific article

Mutation analysis of the coding sequence of the MECP2 gene in infantile autism

scientific article (publication date: October 2002)

Mutation screening and association analysis of six candidate genes for autism on chromosome 7q

scientific article

Parameter estimation for the calibration and variance stabilization of microarray data

scientific article

Physical and genetic characterization reveals a pseudogene, an evolutionary junction, and unstable loci in distal Xq28.

scientific article

Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms

scientific journal article

Primary cutaneous T-cell lymphomas show a deletion or translocation affecting NAV3, the human UNC-53 homologue

scientific article published on September 2005

Quantitative protein microarrays for time-resolved measurements of protein phosphorylation

scientific article published in November 2008

Rare mutations of the DMBT1 gene in human astrocytic gliomas

scientific article

Recent advances in transcription profiling of human cancer

scientific article

Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion

scientific article

SMART amplification combined with cDNA size fractionation in order to obtain large full-length clones

scientific article

Sequential changes of the DMBT1 expression and location in normal lung tissue and lung carcinomas

scientific article published in October 2002

Site-characteristic expression and induction of trefoil factor family 1, 2 and 3 and malignant brain tumor-1 in normal and diseased intrahepatic bile ducts relates to biliary pathophysiology

scientific article published in February 2004

Statistical methods and software for the analysis of highthroughput reverse genetic assays using flow cytometry readouts

scientific article published on 17 August 2006

Systematic analysis of T7 RNA polymerase based in vitro linear RNA amplification for use in microarray experiments

scientific article

Systematic comparison of surface coatings for protein microarrays

scholarly article by Birgit Guilleaume published in December 2005

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing

article published in 2009

The 3of5 web application for complex and comprehensive pattern matching in protein sequences

scientific article published on 16 March 2006

The DNA sequence of the human X chromosome

scientific article published on 17 March 2005

The German cDNA network: cDNAs, functional genomics and proteomics

scientific article published on January 2003

The LIFEdb database in 2006

scientific article

The SRCR/SID region of DMBT1 defines a complex multi-allele system representing the major basis for its variability in cancer

scientific article published in November 2002

The full-ORF clone resource of the German cDNA Consortium

scientific article

The systematic functional characterisation of Xq28 genes prioritises candidate disease genes

scientific article published on 17 February 2006

Thioredoxin, a regulator of gene expression

scientific article published on March 2004

List of works by Annemarie Poustka

A 15q13.3 microdeletion segregating with autism

A compendium to ensure computational reproducibility in high-dimensional classification tasks

A gene for FG syndrome maps in the Xq12-q21.31 region

A genome-wide scan for common alleles affecting risk for autism

A microscope-based screening platform for large-scale functional protein analysis in intact cells

A mutation hot spot for nonspecific X-linked mental retardation in the MECP2 gene causes the PPM-X syndrome

A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder

A physical map of the human genome

Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma

Alternative pre-mRNA processing regulates cell-type specific expression of the IL4l1 and NUP62 genes

An anthropoid-specific segmental duplication on human chromosome 1q22.

Analysis of genetic variations of protein tyrosine kinase fyn and their association with alcohol dependence in two independent cohorts

Analysis of pigmented villonodular synovitis with genome-wide complementary DNA microarray and tissue array technology reveals insight into potential novel therapeutic approaches.

Animal models of autism

Antibody microarrays as an experimental platform for the analysis of signal transduction networks

Association studies of the HOPA dodecamer duplication variant in different subtypes of autism

Automated production of recombinant human proteins as resource for proteome research

Basal transcription activity of the dyskeratosis congenita gene is mediated by Sp1 and Sp3 and a patient mutation in a Sp1 binding site is associated with decreased promoter activity

CDNAs for functional genomics and proteomics: the German Consortium

CRP-ductin, the mouse homologue of gp-340/deleted in malignant brain tumors 1 (DMBT1), binds gram-positive and gram-negative bacteria and interacts with lung surfactant protein D

Candidate genes for cross-resistance against DNA-damaging drugs.

Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis

Combinatorial RNAi for quantitative protein network analysis

Combinatorial synthesis of peptide arrays with a laser printer

Contact spotting of protein microarrays coupled with spike-in of normalizer protein permits time-resolved analysis of ERBB receptor signaling

DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease

DMBT1 expression distinguishes anorectal from cutaneous melanoma

DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands

DMBT1 is frequently downregulated in well-differentiated gastric carcinoma but more frequently upregulated across various gastric cancer types

Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant

Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer

Direct pulsed field gel electrophoresis of Wilms' tumors shows that dna deletions in 11 p 13 are rare

Down-regulation of HLA Class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells.

Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer

Estimating large-scale signaling networks through nested effect models with intervention effects from microarray data

Exclusion of mutations in the MTMR1 gene as a frequent cause of X-linked myotubular myopathy

Expression of acyl-CoA synthetase 5 reflects the state of villus architecture in human small intestine

Expression of deleted in malignant brain tumor-1 (DMBT1) molecule in biliary epithelium is augmented in hepatolithiasis: possible participation in lithogenesis

Extending pathways based on gene lists using InterPro domain signatures

Extraction and processing of high quality RNA from impalpable and macroscopically invisible prostate cancer for microarray gene expression analysis

FARP2, HDLBP and PASK are downregulated in a patient with autism and 2q37.3 deletion syndrome

Filamin (FLN1),plexin (SEX), major palmitoylated proteinp55 (MPP1), and von-Hippel Lindau binding protein (VBP1) are not involved in incontinentia pigmenti type 2

Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer.

From ORFeome to biology: a functional genomics pipeline

Functional impact of global rare copy number variation in autism spectrum disorders

Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle

GOSim--an R-package for computation of information theoretic GO similarities between terms and gene products

Gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking

Gene expression analysis of endobronchial epithelial lining fluid in the evaluation of indeterminate pulmonary nodules.

Generation of a vector system facilitating cloning of DMBT1 variants and recombinant expression of functional full-length DMBT1.

Genetic mapping in mice identifies DMBT1 as a candidate modifier of mammary tumors and breast cancer risk

Genetic variation of Aflatoxin B1 aldehyde reductase genes (AFAR) in human tumour cells

Genomic analysis reveals poor separation of human cardiomyopathies of ischemic and nonischemic etiologies

Global gene expression analysis reveals specific patterns of cell junctions in non-small cell lung cancer subtypes.

Haplotype analysis of the COMT-ARVCF gene region in Israeli anorexia nervosa family trios

High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic

High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins

Human homologue of the murinebare patches/striated gene is not mutated in incontinentia pigmenti type 2

Identification and meta-analysis of a small gene expression signature for the diagnosis of estrogen receptor status in invasive ductal breast cancer

Identification of a common gene expression signature in dilated cardiomyopathy across independent microarray studies

Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancer

Identification of cellular targets for the human papillomavirus E6 and E7 oncogenes by RNA interference and transcriptome analyses

Identification of the bacteria-binding peptide domain on salivary agglutinin (gp-340/DMBT1), a member of the scavenger receptor cysteine-rich superfamily

Infrared-based protein detection arrays for quantitative proteomics

Integrative annotation of 21,037 human genes validated by full-length cDNA clones

LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system

Large scale statistical inference of signaling pathways from RNAi and microarray data

Large-scale protein expression for proteome research

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance

Modeling breast cell cycle regulation--overcoming drug resistance

Molecular cancer phenotype in normal prostate tissue

Molecular characterization of the porcine deleted in malignant brain tumors 1 gene (DMBT1).

Multiplex reverse transcription-polymerase chain reaction combined with on-chip electrophoresis as a rapid screening tool for candidate gene sets

Mutation analysis of the coding sequence of the MECP2 gene in infantile autism

Mutation screening and association analysis of six candidate genes for autism on chromosome 7q

Parameter estimation for the calibration and variance stabilization of microarray data

Physical and genetic characterization reveals a pseudogene, an evolutionary junction, and unstable loci in distal Xq28.

Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms