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A Fluorescent In Vitro Assay to Investigate Paralog-Specific SUMO Conjugation

scientific article published in January 2016

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly

scientific journal article

Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening.

scientific article published on 24 April 2017

Allosteric mechanism for site-specific ubiquitination of FANCD2

scientific article published on 23 December 2019

Autoregulation of Parkin activity through its ubiquitin-like domain

scientific article

DHX15 regulates CMTR1-dependent gene expression and cell proliferation

scientific article published on 01 June 2018

Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.

scientific article published on 7 August 2015

Enzymatic preparation of monoubiquitinated FANCD2 and FANCI proteins

scientific article published on 11 February 2019

Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3

scientific article

Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements

scientific article published on 21 September 2017

Modes of allosteric regulation of the ubiquitination machinery

scientific article published on 15 April 2020

Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity

scientific article published on 17 April 2017

RNF12 X-Linked Intellectual Disability Mutations Disrupt E3 Ligase Activity and Neural Differentiation.

scientific article

SUMO rules: regulatory concepts and their implication in neurologic functions.

scientific article published on 30 August 2013

Small, N-terminal tags activate Parkin E3 ubiquitin ligase activity by disrupting its autoinhibited conformation.

scientific article

Specificity and disease in the ubiquitin system

scientific article published on February 2016

Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1 ⬇️

scientific article published on 12 October 2018

Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation

scientific article published on 16 November 2018

The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL

scientific article

The SUMO2/3 specific E3 ligase ZNF451-1 regulates PML stability.

scientific article published on 22 June 2016

Ubc9 sumoylation controls SUMO chain formation and meiotic synapsis in Saccharomyces cerevisiae

scientific article published on 02 May 2013

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