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List of works by Leigh Knodler

A Brucella Type IV Effector Targets the COG Tethering Complex to Remodel Host Secretory Traffic and Promote Intracellular Replication.

scientific article published on 23 August 2017

A Brucella effector modulates the Arf6-Rab8a GTPase cascade to promote intravacuolar replication

scientific article published on 23 August 2021

A Salmonella Regulator Modulates Intestinal Colonization and Use of Phosphonoacetic Acid

scientific article published on 15 March 2017

Activation of Akt by the bacterial inositol phosphatase, SopB, is wortmannin insensitive. ⬇️

scientific article

Activation of Akt/protein kinase B in epithelial cells by the Salmonella typhimurium effector sigD.

scientific article published on December 2000

Bacterial colonization of host cells in the absence of cholesterol.

scientific article

Brucella Intracellular Replication Requires Trafficking Through the Late Endosomal/Lysosomal Compartment

scientific article published on 04 February 2008

Brucella modulates secretory trafficking via multiple type IV secretion effector proteins.

scientific article

Cloning and expression of a prokaryotic enzyme, arginine deiminase, from a primitive eukaryote Giardia intestinalis.

scientific article

Cloning vectors and fluorescent proteins can significantly inhibit Salmonella enterica virulence in both epithelial cells and macrophages: implications for bacterial pathogenesis studies.

scientific article

Coiled-coil domains enhance the membrane association of Salmonella type III effectors.

scientific article

Controlled Activity of the Salmonella Invasion-Associated Injectisome Reveals Its Intracellular Role in the Cytosolic Population.

scientific article published on 5 December 2017

Dissemination of invasive Salmonella via bacterial-induced extrusion of mucosal epithelia.

scientific article

Eating the strangers within: host control of intracellular bacteria via xenophagy ⬇️

scientific article published on July 10, 2011

Frontline defenders: Goblet cell mediators dictate host-microbe interactions in the intestinal tract during health and disease

scientific article published on 9 November 2017

Functional relatedness in the Inv/Mxi-Spa type III secretion system family

scientific article published on 20 December 2016

Genetic Determinants of Salmonella enterica Serovar Typhimurium Proliferation in the Cytosol of Epithelial Cells

scientific article

Giardia intestinalis: purification and partial amino acid sequence of arginine deiminase

scientific article published on 01 January 1997

Glucose transport in Crithidia luciliae

scientific article published on 01 November 1992

HilD-mediated transcriptional cross-talk between SPI-1 and SPI-2.

scholarly article

Intestinal restriction of Salmonella Typhimurium requires caspase-1 and caspase-11 epithelial intrinsic inflammasomes

scientific article published on 13 April 2020

Intracellular niche-specific profiling reveals transcriptional adaptations required for the cytosolic lifestyle of Salmonella enterica

scientific article published on 30 August 2021

Measurement of Salmonella enterica Internalization and Vacuole Lysis in Epithelial Cells.

scientific article published on January 2017

Multicopy Single-Stranded DNA Directs Intestinal Colonization of Enteric Pathogens

scientific article

Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens

scientific article

Noncanonical inflammasomes: Antimicrobial defense that does not play by the rules.

scientific article published on 24 January 2017

Of Microbes and Membranes: Pathogenic Subversion of Host Cell Processes

scientific article published on 01 December 2008

Paradoxical Modulation of Nociception in Mice by Barbiturate Agonism and Antagonism: Is a GABA Site Involved in Nociception?

scientific article published on 01 January 1991

Poisons, ruffles and rockets: bacterial pathogens and the host cell cytoskeleton.

scientific article

Quantitative assessment of cytosolic Salmonella in epithelial cells.

scientific article published on 06 January 2014

Salmonella and apoptosis: to live or let die?

scientific article

Salmonella and the Inflammasome: Battle for Intracellular Dominance

scientific article

Salmonella enterica

scientific article published on 31 May 2019

Salmonella enterica: living a double life in epithelial cells.

scientific article

Salmonella trafficking is defined by continuous dynamic interactions with the endolysosomal system.

scientific article

Sensing of Bacterial Type IV Secretion via the Unfolded Protein Response ⬇️

scientific article published on February 19, 2013

SopD2 is a novel type III secreted effector of Salmonella typhimurium that targets late endocytic compartments upon delivery into host cells

scientific journal article

SopF, a phosphoinositide binding effector, promotes the stability of the nascent Salmonella-containing vacuole

scientific article published on 24 July 2019

Spatial segregation of virulence gene expression during acute enteric infection with Salmonella enterica serovar Typhimurium

scientific article published on 04 February 2014

Structure-based mutagenesis of SigE verifies the importance of hydrophobic and electrostatic residues in type III chaperone function.

scientific article published on 13 October 2006

The Salmonella SPI1 effector SopB stimulates nitric oxide production long after invasion.

scientific article published in January 2005

The Salmonella effector protein SopB protects epithelial cells from apoptosis by sustained activation of Akt.

scientific article

The evolutionary origins of eukaryotic protein disulfide isomerase domains: new evidence from the Amitochondriate protist Giardia lamblia.

scientific article published in August 2001

The invasion-associated type III secretion system of Salmonella enterica serovar Typhimurium is necessary for intracellular proliferation and vacuole biogenesis in epithelial cells.

scientific article published on January 2002

The mechanism of Salmonella entry determines the vacuolar environment and intracellular gene expression.

scientific article published in January 2006

The transport and metabolism of alanine by Giardia intestinalis

scientific article published on 01 September 1993

The type III secretion system apparatus determines the intracellular niche of bacterial pathogens

scientific article published on 12 April 2016

Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice.

scientific article

Ubiquitination of the bacterial inositol phosphatase, SopB, regulates its biological activity at the plasma membrane.

scientific article published on 13 July 2009

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