List of works -

An high-throughput in vivo screening system to select H3K4-specific histone demethylase inhibitors

scientific article (publication date: 2014)

An in-silico approach aimed to clarify the role of Y181C and K103N HIV-1 reverse transcriptase mutations versus Indole Aryl Sulphones.

scientific article

Arylsulfone-based HIV-1 non-nucleoside reverse transcriptase inhibitors.

scientific article published on December 2013

Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.

scientific article published on 12 May 2007

Arylthioindoles, potent inhibitors of tubulin polymerization.

scientific article

Bicyclic γ-amino acids as inhibitors of γ-aminobutyrate aminotransferase

scientific article published on 25 September 2015

Cdc25B phosphatase inhibitors in cancer therapy: latest developments, trends and medicinal chemistry perspective.

scientific article published on December 2008

Chiral Indolylarylsulfone Non-Nucleoside Reverse Transcriptase Inhibitors as New Potent and Broad Spectrum Anti-HIV-1 Agents.

scientific article published on 19 June 2017

Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.

scientific article published on 21 November 2011

Design, Molecular Modeling, Synthesis, and Anti-HIV-1 Activity of New Indolyl Aryl Sulfones. Novel Derivatives of the Indole-2-carboxamide

article

Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3β inhibitors

scientific article

Discovery of biarylaminoquinazolines as novel tubulin polymerization inhibitors

scientific article

In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses.

scientific article published on 14 July 2015

Indole-2-carboxamides as allosteric modulators of the cannabinoid CB₁ receptor.

scientific article published on 17 May 2012

Indolyl aryl sulphones as HIV-1 reverse transcriptase inhibitors: docking and 3D QSAR studies ⬇️

scientific article published on January 1, 2007

Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules

scientific article published on February 2017

Modeling Epac1 interactions with the allosteric inhibitor AM-001 by co-solvent molecular dynamics

scientific article published on 22 July 2020

Molecular modelling studies on Arylthioindoles as potent inhibitors of tubulin polymerization

scientific article published on 13 May 2011

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

scientific article

New Inhibitors of Indoleamine 2,3-Dioxygenase 1: Molecular Modeling Studies, Synthesis, and Biological Evaluation

scientific article published on 03 October 2016

New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies.

scientific article

Nox2-mediated platelet activation by glycoprotein (GP) VI: Effect of rivaroxaban alone and in combination with aspirin

scientific article published on 13 February 2019

S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis

scientific article

Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B

scientific article published on 04 May 2019

Structural biology in antiviral drug discovery.

scientific article published on 6 September 2016

Structure-Based Drug Design of Potent Pyrazole Derivatives against Rhinovirus Replication

scientific article published on 07 September 2018

Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents.

scientific article published on 25 February 2015

Switching on the activity of 1,5-diaryl-pyrrole derivatives against drug-resistant ESKAPE bacteria: Structure-activity relationships and mode of action studies

scientific article published on 03 June 2019

Targeting the Interaction between the SH3 Domain of Grb2 and Gab2

scientific article published on 07 November 2020

List of works by

An high-throughput in vivo screening system to select H3K4-specific histone demethylase inhibitors

An in-silico approach aimed to clarify the role of Y181C and K103N HIV-1 reverse transcriptase mutations versus Indole Aryl Sulphones.

Arylsulfone-based HIV-1 non-nucleoside reverse transcriptase inhibitors.

Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.

Arylthioindoles, potent inhibitors of tubulin polymerization.

Bicyclic γ-amino acids as inhibitors of γ-aminobutyrate aminotransferase

Cdc25B phosphatase inhibitors in cancer therapy: latest developments, trends and medicinal chemistry perspective.

Chiral Indolylarylsulfone Non-Nucleoside Reverse Transcriptase Inhibitors as New Potent and Broad Spectrum Anti-HIV-1 Agents.

Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.

Design, Molecular Modeling, Synthesis, and Anti-HIV-1 Activity of New Indolyl Aryl Sulfones. Novel Derivatives of the Indole-2-carboxamide

Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3β inhibitors

Discovery of biarylaminoquinazolines as novel tubulin polymerization inhibitors

In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses.

Indole-2-carboxamides as allosteric modulators of the cannabinoid CB₁ receptor.

Indolyl aryl sulphones as HIV-1 reverse transcriptase inhibitors: docking and 3D QSAR studies ⬇️

Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules

Modeling Epac1 interactions with the allosteric inhibitor AM-001 by co-solvent molecular dynamics

Molecular modelling studies on Arylthioindoles as potent inhibitors of tubulin polymerization

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

New Inhibitors of Indoleamine 2,3-Dioxygenase 1: Molecular Modeling Studies, Synthesis, and Biological Evaluation

New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies.

Nox2-mediated platelet activation by glycoprotein (GP) VI: Effect of rivaroxaban alone and in combination with aspirin

S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis

Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B

Structural biology in antiviral drug discovery.

Structure-Based Drug Design of Potent Pyrazole Derivatives against Rhinovirus Replication

Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents.

Switching on the activity of 1,5-diaryl-pyrrole derivatives against drug-resistant ESKAPE bacteria: Structure-activity relationships and mode of action studies

Targeting the Interaction between the SH3 Domain of Grb2 and Gab2