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List of works by Michael Aschner

"Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies"

scientific article

10. Manganese: Its Role in Disease and Health

scientific article published on 14 January 2019

15-Deoxy-Δ12,14-prostaglandin J2 modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes

scientific article published on December 29, 2011

17β-estradiol and tamoxifen protect mice from manganese-induced dopaminergic neurotoxicity

scientific article published on 25 November 2017

A C. elegans Model for the Study of RAGE-Related Neurodegeneration

scientific article published on 04 June 2018

A Golden Anniversary for the National Institute of Environmental Health Sciences

scientific article published in November 2016

A Simple Light Stimulation of Caenorhabditis elegans

scientific article published in February 2016

A chronic iron-deficient/high-manganese diet in rodents results in increased brain oxidative stress and behavioral deficits in the morris water maze

scientific article published on 21 February 2009

A manganese-enhanced diet alters brain metals and transporters in the developing rat.

scientific article published on 16 May 2006

A model for the analysis of competitive relaxation effects of manganese and iron in vivo

scientific article

A new threat from an old enemy: Re‑emergence of coronavirus (Review)

scientific article published on 27 March 2020

A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease

scientific article

A possible neuroprotective action of a vinylic telluride against Mn-induced neurotoxicity.

scientific article

AGEs/RAGE-Related Neurodegeneration: daf-16 as a Mediator, Insulin as an Ameliorant, and C. elegans as an Expedient Research Model

scientific article published on 5 October 2016

Acrylamide stimulates glutamine uptake in Fischer 344 rat astrocytes by a mechanism involving upregulation of the amino acid transport system N.

scientific article published in August 2005

Acrylonitrile has Distinct Hormetic Effects on Acetylcholinesterase Activity in Mouse Brain and Blood that are Modulated by Ethanol

scientific article published on November 17, 2011

Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures

scientific article

Activation of NLRP3 in microglia exacerbates diesel exhaust particles-induced impairment in learning and memory in mice

scientific article published on 27 January 2020

Activation of autophagic flux and the Nrf2/ARE signaling pathway by hydrogen sulfide protects against acrylonitrile-induced neurotoxicity in primary rat astrocytes

scientific article published on 03 May 2018

Acute Methylmercury Exposure and the Hypoxia-Inducible Factor-1α Signaling Pathway under Normoxic Conditions in the Rat Brain and Astrocytes in Vitro

scientific article published on 18 December 2019

Acute glufosinate-based herbicide treatment in rats leads to increased ocular interleukin-1β and c-Fos protein levels, as well as intraocular pressure

scientific article published on 16 January 2019

Acute manganese treatment restores defective autophagic cargo loading in Huntington's disease cell lines

scientific article published on 01 November 2019

Adenosine modulates methylmercuric chloride (MeHgCl)-induced D-aspartate release from neonatal rat primary astrocyte cultures.

scientific article

Advanced Glycation End-Products and Their Receptors: Related Pathologies, Recent Therapeutic Strategies, and a Potential Model for Future Neurodegeneration Studies

scientific article published on 7 April 2016

Adverse health effects of 5G mobile networking technology under real-life conditions

scientific article published on 25 January 2020

Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease

scientific article published on February 2015

Airborne manganese exposure differentially affects end points of oxidative stress in an age- and sex-dependent manner

scientific article published in July 2004

Alterations of oxidative stress biomarkers due to in utero and neonatal exposures of airborne manganese

scientific article published in January 2006

Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system.

scientific article

Altered manganese homeostasis: Implications for BLI-3-dependent dopaminergic neurodegeneration and SKN-1 protection in C. elegans

scientific article published on May 15, 2012

Aluminium levels in hair and urine are associated with overweight and obesity in a non-occupationally exposed population

scientific article published on 17 August 2019

Ammonia increases paracellular permeability of rat brain endothelial cells by a mechanism encompassing oxidative/nitrosative stress and activation of matrix metalloproteinases.

scientific article published on 15 February 2012

An interview with Lucio G. Costa and Michael Aschner, section editors for toxicology

scientific article published on November 15, 2012

Animal models of autism spectrum disorders: information for neurotoxicologists

scientific article

Anti-Cancer Effects of 3, 3'-Diindolylmethane on Human Hepatocellular Carcinoma Cells Is Enhanced by Calcium Ionophore: The Role of Cytosolic Ca2+ and p38 MAPK

scientific article published on 09 October 2019

Anti-aging effects of deuterium depletion on Mn-induced toxicity in a C. elegans model

scientific article published on April 26, 2012

Anti-inflammatory effects of peptide fragments of H2A histone and Oryza Sativa Japonica protein

scientific article published on 03 November 2010

Anticholinesterase toxicity and oxidative stress.

scientific article published on 28 February 2006

Antioxidant properties of blirubin in the model organism, Caenorhabditis elegans

scientific article published on 01 January 2008

Antioxidants prevent the cytotoxicity of manganese in RBE4 cells

scientific article

Antiurolithiatic effects of pentacyclic triterpenes: The distance traveled from therapeutic aspects

scientific article published on 20 April 2020

Application of cell-based biological bioassays for health risk assessment of PM2.5 exposure in three megacities, China

scientific article published on 04 April 2020

Application of novel technologies and mechanistic data for risk assessment under the real-life risk simulation (RLRS) approach

scientific article published on 08 January 2020

Are neuropathological conditions relevant to ethylmercury exposure?

scientific article

Arsenic and manganese alter lead deposition in the rat.

scientific article

Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF-κB Pathways

scientific article published on 15 August 2017

Assessment of copper, iron, zinc and manganese status and speciation in patients with Parkinson's disease: A pilot study

scientific article published on 28 October 2019

Association of exposure to manganese and iron with striatal and thalamic GABA and other neurometabolites - Neuroimaging results from the WELDOX II study

scientific article

Associations between former exposure to manganese and olfaction in an elderly population: Results from the Heinz Nixdorf Recall Study

scientific article

Astrocyte modulation of neurotoxic injury.

scientific article

Astrocyte-mediated methylmercury neurotoxicity

scientific article published on October 2003

Astrocytes as mediators of methylmercury neurotoxicity: effects on D-aspartate and serotonin uptake

scientific article published on 01 January 1994

Astrocytes as potential modulators of mercuric chloride neurotoxicity

scientific article published on 01 December 1994

Astrocytic Oxidative/Nitrosative Stress Contributes to Parkinson's Disease Pathogenesis: The Dual Role of Reactive Astrocytes

scientific article published on 01 August 2019

Atropa belladonna neurotoxicity: Implications to neurological disorders

scientific article published on 10 April 2018

Autophagy in Neurodegenerative Diseases and Metal Neurotoxicity

scientific article

BXD recombinant inbred strains participate in social preference, anxiety and depression behaviors along sex-differences in cytokines and tactile allodynia

scientific article

Bacteria affect Caenorhabditis elegans responses to MeHg toxicity

scientific article published on 19 September 2019

Basal ganglia intensity indices and diffusion weighted imaging in manganese-exposed welders

scientific article published on March 23, 2012

Behavioral effects of developmental methylmercury drinking water exposure in rodents

scientific article published on 07 October 2013

Beta 1, Beta 2 and Beta 3 Adrenergic Receptor Gene Polymorphisms in a Southeastern European Population

article

Biochemical Factors Modulating Cellular Neurotoxicity of Methylmercury

scientific article published on September 20, 2011

Biomarkers of exposure and effect in a working population exposed to lead, manganese and arsenic

scientific article published on 08 October 2018

Biomarkers of mercury toxicity: Past, present, and future trends.

scientific article published on 05 April 2017

Blood cadmium levels and sources of exposure in an adult urban population in southern Brazil

scientific article published on 13 May 2020

Blood manganese levels and associated factors in a population-based study in Southern Brazil

scientific article published on 29 August 2017

Blood reference values for metals in a general adult population in southern Brazil

scientific article published on 10 August 2019

Blood-brain barrier and cell-cell interactions: methods for establishing in vitro models of the blood-brain barrier and transport measurements

scientific article published on January 2006

Brain Manganese and the Balance between Essential Roles and Neurotoxicity

scientific article published on 18 March 2020

Brain accumulation of depleted uranium in rats following 3- or 6-month treatment with implanted depleted uranium pellets

scientific article published in January 2006

Brain barrier systems: a new frontier in metal neurotoxicological research

scientific article published on October 2003

Brain diseases in changing climate

scientific article published on 08 August 2019

C. elegans and Neurodegeneration In Caenorhabditis Elegans: Anatomy, Life Cycles and Biological Functions

scientific article published on 01 January 2012

C. elegans as a model in developmental neurotoxicology

scientific article published on 14 March 2018

C. elegans-An Emerging Model to Study Metal-Induced RAGE-Related Pathologies.

scientific article

COVID-19, an opportunity to reevaluate the correlation between long-term effects of anthropogenic pollutants on viral epidemic/pandemic events and prevalence

scientific article published on 11 May 2020

COVID‑19 in Northern Italy: An integrative overview of factors possibly influencing the sharp increase of the outbreak (Review)

scientific article published on 16 April 2020

Cadmium chloride (CdCl2)-induced metallothionein (MT) expression in neonatal rat primary astrocyte cultures

scientific article published on 01 April 1995

Caenorhabditis elegans and its applicability to studies on restless legs syndrome

scientific article published on 14 March 2019

Caenorhabditis elegans as a model system to study post-translational modifications of human transthyretin

scientific article

Caenorhabditis elegans as a tool for environmental risk assessment: emerging and promising applications for a "nobelized worm"

scientific article published on 01 May 2019

Caenorhabditis elegans metallothioneins protect against toxicity induced by depleted uranium.

scientific article published on 17 July 2009

Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology.

scientific article published on 19 June 2008

Cancer-associated stroke: Pathophysiology, detection and management (Review)

scientific article published on 02 January 2019

Cellular manganese content is developmentally regulated in human dopaminergic neurons

scientific article

Cellular transport and homeostasis of essential and nonessential metals

scientific article published on February 15, 2012

Cellular uptake of lead in the blood-cerebrospinal fluid barrier: Novel roles of Connexin 43 hemichannel and its down-regulations via Erk phosphorylation

scientific article published on 26 February 2016

Cephalic Neuronal Vesicle Formation is Developmentally Dependent and Modified by Methylmercury and sti-1 in Caenorhabditis elegans

scientific article published on 10 October 2020

Changes in Dietary Iron Levels Affect Brain Manganese Accumulation and Distribution

scientific article published on 20 June 2008

Changes in dietary iron exacerbate regional brain manganese accumulation as determined by magnetic resonance imaging

scientific article

Changes in rat urinary porphyrin profiles predict the magnitude of the neurotoxic effects induced by a mixture of lead, arsenic and manganese

scientific article published on 31 October 2014

Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: a trimethyltin study

journal article published in 2018

Chapter 8 - Nanoparticles: Transport across the olfactory epithelium and application to the assessment of brain function in health and disease

scientific article published on 08 December 2009

Characteristics of manganese (Mn) transport in rat brain endothelial (RBE4) cells, an in vitro model of the blood-brain barrier

scientific article published on 16 September 2005

Characterization of the effects of methylmercury on Caenorhabditis elegans

scientific article published on 31 March 2009

Chemical Speciation of Selenium and Mercury as Determinant of Their Neurotoxicity.

scientific article published in January 2017

Chlorpyrifos-, diisopropylphosphorofluoridate-, and parathion-induced behavioral and oxidative stress effects: are they mediated by analogous mechanisms of action?

scientific article published on 17 September 2012

Chronic dietary chlorpyrifos causes long-term spatial memory impairment and thigmotaxic behavior

scientific article published on 31 December 2015

Chronic ethanol produces increased taurine transport and efflux in cultured astrocytes

scientific article

Chronic exposure to manganese alters brain responses to amphetamine: a pharmacological magnetic resonance imaging study

scientific article

Chronic exposure to methylmercury induces puncta formation in cephalic dopaminergic neurons in Caenorhabditis elegans

scientific article published on 11 January 2020

Circulating biomarkers of neurotoxicity: identifying fluidic endpoints correlating with central nervous system toxicity in a rodent model of neurotoxicity

abstract published in 2019

Cognitive and neuroimaging changes in healthy immigrants upon relocation to a high altitude: A panel study

scientific article

Colonic Injuries Induced by Inhalational Exposure to Particulate-Matter Air Pollution.

scientific article published on 9 April 2019

Combined exposure to methylmercury and manganese during L1 larval stage causes motor dysfunction, cholinergic and monoaminergic up-regulation and oxidative stress in L4 Caenorhabditis elegans

scholarly article by Maria Rosa C Schetinger et al published 15 October 2018 in Toxicology

Comparative study of quercetin and its two glycoside derivatives quercitrin and rutin against methylmercury (MeHg)-induced ROS production in rat brain slices.

scientific article published on 10 November 2009

Comparative study on methyl- and ethylmercury-induced toxicity in C6 glioma cells and the potential role of LAT-1 in mediating mercurial-thiol complexes uptake

scientific article published on 30 May 2013

Comparative study on short- and long-term behavioral consequences of organophosphate exposure: relationship to AChE mRNA expression

scientific article published on 27 November 2013

Comparative study on the response of rat primary astrocytes and microglia to methylmercury toxicity

scientific article

Comparing the Effects of Ferulic Acid and Sugarcane Aqueous Extract in In Vitro and In Vivo Neurotoxic Models

scientific article published on 15 June 2018

Comparing the Neuroprotective Effects of Caffeic Acid in Rat Cortical Slices and Caenorhabditis elegans: Involvement of Nrf2 and SKN-1 Signaling Pathways

scientific article published on 26 November 2019

Comparison between 5-aminosalicylic acid (5-ASA) and para-aminosalicylic acid (4-PAS) as potential protectors against Mn-induced neurotoxicity

scientific article published on 15 January 2013

Comparison of alterations in amino acids content in cultured astrocytes or neurons exposed to methylmercury separately or in co-culture

scientific article published on 31 January 2009

Comparison of the Toxic Effects of Quinolinic Acid and 3-Nitropropionic Acid in C. elegans: Involvement of the SKN-1 Pathway

scientific article published on 18 August 2017

Comparison of the neurotoxicity associated with cobalt nanoparticles and cobalt chloride in Wistar rats

scientific article published on 05 March 2019

Complex methylmercury-cysteine alters mercury accumulation in different tissues of mice.

scientific article published in October 2010

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

scientific article published on 12 February 2018

Considerations on manganese (Mn) treatments for in vitro studies

scientific article published on 05 February 2014

Considerations on methylmercury (MeHg) treatments in in vitro studies

scientific article published on June 1, 2012

Correction to: Comparing the Neuroprotective Effects of Caffeic Acid in Rat Cortical Slices and Caenorhabditis elegans: Involvement of Nrf2 and SKN-1 Signaling Pathways

scientific article published on 01 March 2020

Cultured lymphocytes from autistic children and non-autistic siblings up-regulate heat shock protein RNA in response to thimerosal challenge

scientific article published on 16 June 2006

Curcumin attenuates copper-induced oxidative stress and neurotoxicity in Drosophila melanogaster

scientific article published on 27 January 2020

Curcumin pretreatment protects against acute acrylonitrile-induced oxidative damage in rats

scientific article published on 11 November 2009

Curcumin protects against methylmercury-induced cytotoxicity in primary rat astrocytes by activating the Nrf2/ARE pathway independently of PKCδ

scientific article published on 19 July 2019

Current needs and future directions of occupational safety and heath in a globalized world

scientific article published on 20 October 2011

DR4 mediates the progression, invasion, metastasis and survival of colorectal cancer through the Sp1/NF1 switch axis on genomic locus

scientific article published on 15 February 2018

Deficiency in the manganese efflux transporter SLC30A10 induces severe hypothyroidism in mice

scientific article published in May 2017

Depleted uranium is not toxic to rat brain endothelial (RBE4) cells

scientific article published on April 2006

Determination of trace metals in fruit juices in the Portuguese market.

scientific article

Determining the oxidation states of manganese in NT2 cells and cultured astrocytes

scientific article published on 14 November 2005

Determining the oxidation states of manganese in PC12 and nerve growth factor-induced PC12 cells

scientific article published on 31 March 2005

Developmental Neurotoxicity of Lead

scientific article published in January 2017

Developmental aspects of blood-brain barrier (BBB) and rat brain endothelial (RBE4) cells as in vitro model for studies on chlorpyrifos transport

scientific article

Developmental neuropathology of environmental agents.

scientific article published on January 2004

Differential deposition of manganese in the rat brain following subchronic exposure to manganese: a T1-weighted magnetic resonance imaging study

scientific article published on 01 November 2008

Differential inflammatory response to acrylonitrile in rat primary astrocytes and microglia

scientific article published on 11 March 2014

Differential interaction of hGDH1 and hGDH2 with manganese: Implications for metabolism and toxicity

scientific article published on 30 March 2015

Differential protection of pre- versus post-treatment with curcumin, Trolox, and N-acetylcysteine against acrylonitrile-induced cytotoxicity in primary rat astrocytes

scientific article published on 24 September 2015

Differential response to acrylonitrile toxicity in rat primary astrocytes and microglia

scientific article published on April 26, 2013

Differential susceptibility of PC12 and BRL cells and the regulatory role of HIF-1α signaling pathway in response to acute methylmercury exposure under normoxia

scientific article published on 24 May 2020

Diphenyl diselenide protects against methylmercury-induced inhibition of thioredoxin reductase and glutathione peroxidase in human neuroblastoma cells: a comparison with ebselen

scientific article published on 6 April 2017

Diphenyl diselenide reverses gastric lesions in rats: Involvement of oxidative stress.

scientific article published on 20 June 2008

Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in adult mice

scientific article published on 29 November 2008

Diphenyl ditelluride targets brain selenoproteins in vivo: inhibition of cerebral thioredoxin reductase and glutathione peroxidase in mice after acute exposure

scientific article published on 12 August 2012

Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism

scientific article (publication date: 2012)

Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposure

scientific article published on 21 October 2009

Disparity in Risk Factor Severity for Early Childhood Blood Lead among Predominantly African-American Black Children: The 1999 to 2010 US NHANES

scientific article published on 28 February 2020

Disruption of astrocytic glutamine turnover by manganese is mediated by the protein kinase C pathway

scientific article published on 2 August 2011

Docosahexaenoic acid may act as a neuroprotector for methylmercury-induced neurotoxicity in primary neural cell cultures.

scientific article published on 20 June 2008

Does methylmercury-induced hypercholesterolemia play a causal role in its neurotoxicity and cardiovascular disease?

scientific article published on 17 August 2012

Does the CD33 rs3865444 Polymorphism Confer Susceptibility to Alzheimer's Disease?

scientific article published on 22 February 2020

Dopaminergic neurotoxicity ofS‐ethylN,N‐dipropylthiocarbamate (EPTC), molinate, andS‐methyl‐N,N‐diethylthiocarbamate (MeDETC) inCaenorhabditis elegans

scientific article published on July 19, 2013

Down-regulation of early ionotrophic glutamate receptor subunit developmental expression as a mechanism for observed plasticity deficits following gestational exposure to benzo(a)pyrene

scientific article

Duration of airborne-manganese exposure in rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity

scientific article published on 30 January 2008

Dysregulation of Glutamate Cycling Mediates Methylmercury-Induced Neurotoxicity

scientific article published in January 2016

Dysregulation of TFEB contributes to manganese-induced autophagic failure and mitochondrial dysfunction in astrocytes

scientific article published on 24 November 2019

Early-life exposure to methylmercury in wildtype and pdr-1/parkin knockout C. elegans

scientific article published on 23 April 2013

Editorial

Editorial: Sex and Gene-Dependent Neurotoxicity

article

Effect of manganese on acetylcholinesterase activity

scholarly article by Dinamene Santos et al published August 2012 in Toxicology

Effect of methylmercury on glutamate metabolism in cerebellar astrocytes in culture

scientific article published on September 1, 2003

Effects of acrylamide on primary neonatal rat astrocyte functions

scientific article published in August 2005

Effects of acrylonitrile on antioxidant status of different brain regions in rats

scientific article published on 20 May 2009

Effects of developmental manganese, stress, and the combination of both on monoamines, growth, and corticosterone

scientific article

Effects of diphenyl diselenide on methylmercury toxicity in rats

scientific article published on 29 December 2013

Effects of inhaled manganese on biomarkers of oxidative stress in the rat brain

scientific article published on 22 May 2006

Effects of manganese (Mn) on the developing rat brain: oxidative-stress related endpoints.

scientific article published in July 2002

Effects of manganese on oxidative stress in CATH.a cells

scientific article

Effects of methylmercury on primary brain cells in mono- and co-culture

scientific article published on 15 June 2005

Effects of nanoparticles on the adhesion and cell viability on astrocytes.

scientific article published in January 2007

Elemental bioimaging of Cisplatin in Caenorhabditis elegans by LA-ICP-MS

scientific article published on July 2015

Elemental bioimaging of manganese uptake in C. elegans.

scientific article published on 30 January 2014

Enthusiasm Scientifically Oriented: The Preface for the Special Issue Dedicated to Jan Albrecht

scientific article published on 11 January 2017

Environmental exposure, obesity, and Parkinson's disease: lessons from fat and old worms

scientific article

Environmental influence on neurodevelopmental disorders: Potential association of heavy metal exposure and autism

scientific article published on 29 August 2020

Epigenetic influence of environmentally neurotoxic metals

scientific article published on 31 August 2020

Erratum to: The Role of Autophagy Dysregulation in Manganese-Induced Dopaminergic Neurodegeneration

scientific article published on 20 June 2014

Estrogen and tamoxifen protect against Mn-induced toxicity in rat cortical primary cultures of neurons and astrocytes

scientific article published on 21 April 2009

Estrogen and tamoxifen reverse manganese-induced glutamate transporter impairment in astrocytes

scientific article published on 22 April 2009

Estrogen attenuates manganese-induced glutamate transporter impairment in rat primary astrocytes

scientific article published on 10 August 2012

Evaluation of neurobehavioral and neuroinflammatory end-points in the post-exposure period in rats sub-acutely exposed to manganese

scientific article

Evaluation of the biological effects of (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate, a new telluroamino acid derivative of aspartic acid

scientific article

Exposure and susceptibility: schizophrenia in a young man following prolonged high exposures to organic solvents

scientific article published on 07 July 2010

Exposure, epidemiology, and mechanism of the environmental toxicant manganese

scientific article

Extracellular dopamine and alterations on dopamine transporter are related to reserpine toxicity in Caenorhabditis elegans

scientific article published on 13 January 2015

Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans

scientific article

F3-Isoprostanes as a Measure of in vivo Oxidative Damage in Caenorhabditis elegans

scientific article

Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation

scientific article

Foreword: JEM spotlight: metal speciation related to neurotoxicity in humans

scientific article published on 27 March 2009

Free radical formation in cerebral cortical astrocytes in culture induced by methylmercury

scientific article published in September 2004

From the Cover: Manganese and Rotenone-Induced Oxidative Stress Signatures Differ in iPSC-Derived Human Dopamine Neurons

scientific article

Frontiers in Toxicogenomics in the Twenty-First Century-the Grand Challenge: To Understand How the Genome and Epigenome Interact with the Toxic Environment at the Single-Cell, Whole-Organism, and Multi-Generational Level

scientific article published on 9 November 2017

GPR30 Regulates Glutamate Transporter GLT-1 Expression in Rat Primary Astrocytes

scientific article published on May 29, 2012

GSK-3β, a double-edged sword in Nrf2 regulation: Implications for neurological dysfunction and disease

scientific article published on 10 July 2018

Gain of function of Kir4.1 channel increases cell resistance to changes of potassium fluxes and cell volume evoked by ammonia and hypoosmotic stress

scientific article published on 01 November 2010

Gender and manganese exposure interactions on mouse striatal neuron morphology

scientific article

Gene-environment interactions in neurotoxicology: the 12th biennial meeting of the International Neurotoxicology Association

scientific article published on 31 March 2010

Gene-environment interactions: neurodegeneration in non-mammals and mammals

scientific article (publication date: September 2010)

Generating Bacterial Foods in Toxicology Studies with Caenorhabditis elegans

scientific article published on 01 June 2020

Genetic aspects of behavioral neurotoxicology

scientific article

Genetic dys-regulation of astrocytic glutamate transporter EAAT2 and its implications in neurological disorders and manganese toxicity

scientific article

Genetic factors and manganese-induced neurotoxicity

scientific article

Genistein alleviates lead-induced neurotoxicity in vitro and in vivo: Involvement of multiple signaling pathways

scientific article published on 18 January 2016

Genome-Wide Analyses of Metal Responsive Genes in Caenorhabditis elegans

scientific article published on April 10, 2012

Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human Induced Pluripotent Stem Cells

scientific article

Genotoxicity of organoselenium compounds in human leukocytes in vitro.

scientific article published on 2 April 2009

Glia and methylmercury neurotoxicity

scientific article

Globus pallidus: a target brain region for divalent metal accumulation associated with dietary iron deficiency

scientific article

Glutamate/aspartate transporter (GLAST), taurine transporter and metallothionein mRNA levels are differentially altered in astrocytes exposed to manganese chloride, manganese phosphate or manganese sulfate

scientific article published in September 2002

Glutathione modulation influences methyl mercury induced neurotoxicity in primary cell cultures of neurons and astrocytes

scientific article published on 2 March 2006

Growth hormone administration to aged animals reduces disulfide glutathione levels in hippocampus

scientific article published on 21 October 2005

Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system

scientific article published on 30 December 2008

Guarana (Paullinia cupana Mart.) attenuates methylmercury-induced toxicity in Caenorhabditis elegans

scientific article published on 24 August 2016

Haloperidol Interactions with the dop-3 Receptor in Caenorhabditis elegans

scientific article published on 15 September 2020

Hemolytic and genotoxic evaluation of organochalcogens in human blood cells in vitro.

scientific article published on 27 May 2009

High level of methylmercury exposure causes persisted toxicity in Nauphoeta cinerea

scientific article published on 16 December 2019

High-resolution multi-photon imaging of morphological structures of caenorhabditis elegans

scientific article published on May 2015

Highly sensitive isotope-dilution liquid-chromatography-electrospray ionization-tandem-mass spectrometry approach to study the drug-mediated modulation of dopamine and serotonin levels in Caenorhabditis elegans.

scientific article

Hormetic Effects of Acute Methylmercury Exposure on GRP78 Expression in Rat Brain Cortex

scientific article published on February 10, 2012

Hormetic Neurobehavioral effects of low dose toxic chemical mixtures in real-life risk simulation (RLRS) in rats

scientific article published on 27 December 2018

Hormetic effect of methylmercury on Caenorhabditis elegans

scientific article published on August 5, 2010

Human-induced pluripotent stems cells as a model to dissect the selective neurotoxicity of methylmercury

scientific article published on 10 February 2019

Huntington's disease associated resistance to Mn neurotoxicity is neurodevelopmental stage and neuronal lineage dependent

scientific article published on 20 September 2019

Huntington's disease genotype suppresses global manganese-responsive processes in pre-manifest and manifest YAC128 mice

scientific article published on 18 May 2020

Hypothyroidism induced by loss of the manganese efflux transporter SLC30A10 may be explained by reduced thyroxine production

scientific article published on 31 August 2017

Identification of a selective manganese ionophore that enables nonlethal quantification of cellular manganese

scientific article published on 11 February 2020

Immune and Inflammatory Responses in the Central Nervous System: Modulation by Astrocytes

article

In vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells is inhibited by the ethylmercury-containing preservative thimerosal

scientific article published on January 2005

In vivo manganese exposure modulates Erk, Akt and Darpp-32 in the striatum of developing rats, and impairs their motor function

scientific article

In vivo measurement of brain GABA concentrations by magnetic resonance spectroscopy in smelters occupationally exposed to manganese

scientific article

Increased manganese uptake by primary astrocyte cultures with altered iron status is mediated primarily by divalent metal transporter

scientific article

Induction or inhibition of cytochrome P450 2E1 modifies the acute toxicity of acrylonitrile in rats: biochemical evidence

scientific article published on 3 February 2010

Inhibition of ATP citrate lyase (ACLY) protects airway epithelia from PM-induced epithelial-mesenchymal transition

scientific article published on 18 October 2018

Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases

scientific article published on 06 January 2011

Insights into the differential toxicological and antioxidant effects of 4-phenylchalcogenil-7-chloroquinolines in Caenorhabditis elegans

scientific article published on 30 May 2017

Interactions between excessive manganese exposures and dietary iron-deficiency in neurodegeneration

scientific article published on May 2005

Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures

scientific article published on 01 November 1994

Introducing cloned genes into cultured neurons providing novel in vitro models for neuropathology and neurotoxicity studies

scientific article published on 14 February 2011

Involvement of AAT transporters in methylmercury toxicity in Caenorhabditis elegans

scientific article published on May 10, 2013

Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity.

scientific article published on March 2007

Involvement of heat shock proteins on Mn-induced toxicity in Caenorhabditis elegans

scientific article

Involvement of striatal lipid peroxidation and inhibition of calcium influx into brain slices in neurobehavioral alterations in a rat model of short-term oral exposure to manganese

scientific article

Iron and manganese-related CNS toxicity: mechanisms, diagnosis and treatment

scientific article published on 21 February 2019

Iron deficient and manganese supplemented diets alter metals and transporters in the developing rat brain

scientific journal article

Is Triclosan a neurotoxic agent?

scientific article published on 22 February 2017

LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia

scientific article published in PLoS ONE

Lack of association between autism and four heavy metal regulatory genes

scientific article published on July 20, 2011

Leaching of trace elements from biological tissue by formalin fixation

scientific article published on 19 October 2007

Lead (Pb) exposure induces dopaminergic neurotoxicity in Caenorhabditis elegans: Involvement of the dopamine transporter

scientific article published on 11 August 2019

Lead increases inositol 1,4,5-trisphosphate levels but does not interfere with calcium transients in primary rat astrocytes

scientific article published in July 1993

Lead, Arsenic, and Manganese Metal Mixture Exposures: Focus on Biomarkers of Effect

scientific article

Lipid peroxidation and changes of trace elements in mice treated with paradichlorobenzene

scientific article published on 4 November 2009

Local effects and global impact in neurotoxicity and neurodegeneration: the Xi'an International Neurotoxicology Conference

scientific article published on 15 May 2012

Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans

scientific article published on 13 March 2015

MALAT1 rs664589 Polymorphism Inhibits Binding to miR-194-5p, Contributing to Colorectal Cancer Risk, Growth, and Metastasis

scientific article published on 16 July 2019

METALLOTHIONEIN AND AUTISM

scientific article published in October 2008

MPO promoter polymorphism rs2333227 enhances malignant phenotypes of colorectal cancer by altering the binding affinity of AP-2α.

scientific article published on 14 March 2018

Maintaining Translational Relevance in Animal Models of Manganese Neurotoxicity

scientific article published on 25 March 2020

Manganese (Mn) and iron (Fe): interdependency of transport and regulation

scientific article

Manganese Acts upon Insulin/IGF Receptors to Phosphorylate AKT and Increase Glucose Uptake in Huntington's Disease Cells

scientific article published on 04 December 2019

Manganese Alters Rat Brain Amino Acids Levels

scientific article published on September 13, 2012

Manganese Control of Glutamate Transporters' Gene Expression

scientific article published in January 2017

Manganese Homeostasis and Transport

scientific article (publication date: 5 December 2012)

Manganese Induced neurodegenerative diseases and possible therapeutic approaches

scientific article published on 17 August 2020

Manganese Is Essential for Neuronal Health

scientific article published on 13 May 2015

Manganese Transport into the Brain: Putative Mechanisms

scientific article published on 01 May 2008

Manganese accumulates in iron-deficient rat brain regions in a heterogeneous fashion and is associated with neurochemical alterations

scientific article

Manganese accumulation in striatum of mice exposed to toxic doses is dependent upon a functional dopamine transporter.

scientific article published on November 2005

Manganese and Neurodegeneration

Manganese and aging

scientific article

Manganese and its role in Parkinson's disease: from transport to neuropathology

scientific article

Manganese as a potential confounder of serum prolactin

scientific article published on August 2006

Manganese causes differential regulation of glutamate transporter (GLAST) taurine transporter and metallothionein in cultured rat astrocytes

scientific article published in October 2002

Manganese disrupts astrocyte glutamine transporter expression and function

scientific article published on 15 May 2009

Manganese dosimetry: species differences and implications for neurotoxicity

scientific article

Manganese efflux in Parkinsonism: Insights from newly characterized SLC30A10 mutations

scientific article published on January 26, 2013

Manganese exposure among smelting workers: blood manganese-iron ratio as a novel tool for manganese exposure assessment

journal article published in 2009

Manganese exposure and induced oxidative stress in the rat brain

scientific article published in December 2004

Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia

scientific article published on 5 May 2009

Manganese homeostasis in the nervous system

scientific article

Manganese in diet: bioaccessibility, adequate intake and neurotoxicological effects

scientific article published on 16 April 2020

Manganese in health and disease

scientific article published on January 2013

Manganese in human parenteral nutrition: considerations for toxicity and biomonitoring

scientific article

Manganese in the shower: mere speculation over an invalidated public health danger

scientific article published on 13 September 2005

Manganese induces oxidative impairment in cultured rat astrocytes.

scientific article published on 27 April 2007

Manganese inhalation by rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity

scientific article published on 7 March 2007

Manganese metabolism in humans

scientific article published in March 2018

Manganese neurotoxicity

scientific article published on March 2004

Manganese neurotoxicity and glutamate-GABA interaction

scientific article published on September 1, 2003

Manganese neurotoxicity and the role of reactive oxygen species

scientific article

Manganese neurotoxicity may underlie the association between early life iron deficiency and impaired spatial cognition in neonatal piglets

scientific article published on 01 April 2013

Manganese neurotoxicity: a focus on glutamate transporters

scientific article published on 21 May 2013

Manganese neurotoxicity: a focus on the neonate

scientific article published on 22 September 2006

Manganese transport by rat brain endothelial (RBE4) cell-based transwell model in the presence of astrocyte conditioned media

scientific article published in July 2005

Manganese transport in eukaryotes: the role of DMT1

scientific article

Manganese transport via the transferrin mechanism

scientific article published on November 9, 2012

Manganese uptake and efflux in cultured rat astrocytes

scientific article published on 01 February 1992

Manganese-Induced Parkinsonism and Parkinson's Disease: Shared and Distinguishable Features

scientific article

Manganese-Induced Toxicity in C. elegans: What Can We Learn from the Transcriptome?

scientific article published in 2022

Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox

scientific article published on 6 February 2013

Manganese-induced Neurotoxicity: From C. elegans to Humans

scientific article

Manganese-induced cytotoxicity in dopamine-producing cells

journal article published in 2004

Manganese-induced dopaminergic neurodegeneration: insights into mechanisms and genetics shared with Parkinson's disease

scientific article published on October 2009

Manganese-induced oxidative DNA damage in neuronal SH-SY5Y cells: Attenuation of thymine base lesions by glutathione and N-acetylcysteine

scientific article published on January 4, 2013

Manganese.

scientific article

Manganese: pharmacokinetics and molecular mechanisms of brain uptake

scientific article

Manganese: recent advances in understanding its transport and neurotoxicity

scientific article

Manganese‐induced downregulation of astroglial glutamine transporter SNAT3 involves ubiquitin‐mediated proteolytic system

scientific article published on December 1, 2010

Measurement of Isoprostanes as Markers of Oxidative Stress

scientific article published on January 1, 2011

Measurement of isoprostanes as markers of oxidative stress in neuronal tissue

scientific article

Measuring brain manganese and iron accumulation in rats following 14 weeks of low-dose manganese treatment using atomic absorption spectroscopy and magnetic resonance imaging

scientific article published on 30 January 2008

Mechanism of Mn(II)-mediated dysregulation of glutamine-glutamate cycle: focus on glutamate turnover

scientific article

Mechanisms and Modifiers of Methylmercury-Induced Neurotoxicity

scientific article

Mechanisms of methylmercury-induced neurotoxicity: evidence from experimental studies.

scientific article

Mefloquine induces oxidative stress and neurodegeneration in primary rat cortical neurons

scientific article

Mefloquine neurotoxicity is mediated by non-receptor tyrosine kinase

scientific article published on January 15, 2011

Mercuric chloride inhibits the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells

scientific article published on March 2006

Mercury in Our Food

scientific article published on 24 May 2019

Mercury toxicity

scientific article published on 3 September 2012

Metabolic effects of manganese in the nematode Caenorhabditis elegans through DAergic pathway and transcription factors activation.

scientific article

Metabolomics analysis explores the rescue to neurobehavioral disorder induced by maternal PM2.5 exposure in mice

scientific article published on 27 November 2018

Metal environmental contamination within different human exposure context- specific and non-specific biomarkers

scientific article published on 11 January 2020

Metal-induced neurodegeneration in C. elegans

scientific article published on May 20, 2013

Metallothionein in the central nervous system: Roles in protection, regeneration and cognition

scientific article published on 19 January 2008

Metallothionein induction in fetal rat brain and neonatal primary astrocyte cultures by in utero exposure to elemental mercury vapor (Hg0).

scientific article published on December 1997

Metallothionein induction in neonatal rat primary astrocyte cultures protects against methylmercury cytotoxicity

scientific article published on 01 October 1995

Metallothioneins: mercury species-specific induction and their potential role in attenuating neurotoxicity

scientific article published in October 2006

Metals and Neurodegeneration

scientific article

Metals, oxidative stress and neurodegeneration: A focus on iron, manganese and mercury

scientific article published on December 21, 2012

Methods for the Detection of Autophagy in Mammalian Cells

scientific article published on August 2016

Methylmercury Affects the Expression of Hypothalamic Neuropeptides That Control Body Weight in C57BL/6J Mice

scientific article published on 01 June 2018

Methylmercury Epigenetics

scientific article published on 09 November 2019

Methylmercury Induces Metabolic Alterations in Caenorhabditis elegans: Role for C/EBP Transcription Factor

scientific article published on 01 March 2020

Methylmercury alters the activities of Hsp90 client proteins, prostaglandin E synthase/p23 (PGES/23) and nNOS.

scientific article

Methylmercury alters the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells

scientific article published on December 2005

Methylmercury and brain development: A review of recent literature

scientific article published on 04 March 2016

Methylmercury augments Nrf2 activity by downregulation of the Src family kinase Fyn.

scientific article

Methylmercury enhances arachidonic acid release and cytosolic phospholipase A2 expression in primary cultures of neonatal astrocytes

scientific article published in October 2002

Methylmercury induces acute oxidative stress, altering Nrf2 protein level in primary microglial cells

scientific article

Methylmercury induces oxidative injury, alterations in permeability and glutamine transport in cultured astrocytes.

scientific article published on 19 December 2006

Methylmercury stimulates arachidonic acid release and cytosolic phospholipase A2 expression in primary neuronal cultures

scientific journal article

Methylmercury toxicity and Nrf2-dependent detoxification in astrocytes

scientific article published on 23 September 2008

Methylmercury's chemistry: From the environment to the mammalian brain

scientific article published on 17 January 2019

Methylmercury-Induced Neurotoxicity: Focus on Pro-oxidative Events and Related Consequences.

scientific article published in January 2017

Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen.

scientific article published on 15 February 2011

Methylmercury-induced alterations in excitatory amino acid transport in rat primary astrocyte cultures

scientific article published in February 1993

Methylmercury-induced reactive oxygen species formation in neonatal cerebral astrocytic cultures is attenuated by antioxidants

scientific article

Methylmercury: recent advances in the understanding of its neurotoxicity

scientific article

Microglia Activation and Gene Expression Alteration of Neurotrophins in the Hippocampus Following Early Life Exposure to E-cigarette Aerosols in a Murine Model.

scientific article published on 17 November 2017

Mir-203-mediated tricellulin mediates lead-induced in vitro loss of blood-cerebrospinal fluid barrier (BCB) function

scientific article published on 12 May 2015

Mitochondrial Redox Dysfunction and Environmental Exposures

scientific article

Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability transition pore opening.

scientific article

Mitochondrial-dependent manganese neurotoxicity in rat primary astrocyte cultures

scientific article published on 11 February 2008

Modified expression of antioxidant genes in lobster cockroach, Nauphoeta cinerea exposed to methylmercury and monosodium glutamate

scientific article published on 31 January 2020

Modulation of cholinergic systems by manganese

scientific article published on 22 August 2007

Modulation of methylmercury uptake by methionine: prevention of mitochondrial dysfunction in rat liver slices by a mimicry mechanism

scientific article published on 27 January 2011

Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes

scientific article published on 17 March 2005

Molecular Docking of Isolated Alkaloids for Possible α-Glucosidase Inhibition

scientific article published on 27 September 2019

Molecular Pathways Associated With Methylmercury-Induced Nrf2 Modulation

scholarly article by Takamitsu Unoki et al published 2018 in Frontiers in Genetics

Morphometric analysis in neurodegenerative disorders

scientific article

Multiple organ injury in male C57BL/6J mice exposed to ambient particulate matter in a real-ambient PM exposure system in Shijiazhuang, China

article

NAD+ Supplementation Attenuates Methylmercury Dopaminergic and Mitochondrial Toxicity in Caenorhabditis Elegans

scientific article published on 10 February 2016

Neonatal Rat Primary Microglia: Isolation, Culturing, and Selected Applications

scientific article published on February 1, 2010

Neurobehavioral and biochemical changes in Nauphoeta cinerea following dietary exposure to chlorpyrifos.

scientific article published on 11 December 2015

Neurodevelopmental Effects of Mercury

scientific article published on 24 May 2018

Neuroimaging identifies increased manganese deposition in infants receiving parenteral nutrition

scientific article

Neuronal oxidative injury and dendritic damage induced by carbofuran: protection by memantine

scientific article published in November 2006

Neuroprotection by tamoxifen in focal cerebral ischemia is not mediated by an agonist action at estrogen receptors but is associated with antioxidant activity

scientific article published on 24 January 2007

Neuroprotection of luteolin against methylmercury-induced toxicity in lobster cockroach Nauphoeta cinerea

scientific article published on 3 February 2016

Neuroprotective Effects of Quercetin in Alzheimer's Disease

scientific article published on 30 December 2019

Neuroprotective and Therapeutic Strategies for Manganese-Induced Neurotoxicity

scientific article published on 26 May 2017

Neurotoxic effect of active ingredients in sunscreen products, a contemporary review

scientific article published on 27 May 2017

Neurotoxic mechanisms of fish-borne methylmercury

scientific article published on September 1, 2002

Neurotoxic potential of depleted uranium effects in primary cortical neuron cultures and in Caenorhabditis elegans

scientific article

Neurotoxicity of Metal Mixtures

scientific article

Neurotoxicity of depleted uranium: reasons for increased concern

scientific article

Neurotoxicity of e-cigarettes

scientific article published on 05 March 2020

Neurotoxicity of fragrance compounds: A review

scientific article

Neurotoxicity of manganese: Indications for future research and public health intervention from the Manganese 2016 conference

scientific article published in January 2018

Neurotoxicity of metals

scientific article published on January 2015

Neurotoxicology: principles and considerations of in vitro assessment.

scientific article

New Insights on the Role of Manganese in Alzheimer's Disease and Parkinson's Disease

scientific article published on 22 September 2019

New strategies in neuroprotection and neurorepair

scientific article published on 23 August 2011

New tools for the quantitative assessment of prodrug delivery and neurotoxicity

scientific article published on 27 February 2015

Nickel-Induced Developmental Neurotoxicity in C. elegans Includes Cholinergic, Dopaminergic and GABAergic Degeneration, Altered Behaviour, and Increased SKN-1 Activity

scientific article published on 08 February 2020

Nickel-induced neurodegeneration in the hippocampus, striatum and cortex; an ultrastructural insight, and the role of caspase-3 and α-synuclein

scientific article published on 25 May 2018

Nicotine protects against manganese and iron-induced toxicity in SH-SY5Y cells: Implication for Parkinson's disease

scientific article published on 14 December 2018

Nrf2-regulated miR-380-3p blocks the translation of Sp3 protein and its mediation of paraquat-induced toxicity in mouse neuroblastoma N2a cells

scientific article published on 31 July 2019

Null allele mutants of trt-1, the catalytic subunit of telomerase in Caenorhabditis elegans, are less sensitive to Mn-induced toxicity and DAergic degeneration

scientific article

Nutritional aspects of manganese homeostasis.

scientific article

Obfuscating transparency?

scientific article published on 11 July 2018

Occupational Exposure to Manganese and Fine Motor Skills in Elderly Men: Results from the Heinz Nixdorf Recall Study

scientific article published on 01 November 2017

Open issues from the 15th International Conference on Manganese

scientific article published in July 2002

Optimization of Fluorescence Assay of Cellular Manganese Status for High Throughput Screening

scientific article published on November 20, 2012

Organochalcogens Inhibit Mitochondrial Complexes I and II in Rat Brain: Possible Implications for Neurotoxicity

scientific article published on 06 December 2012

Organoselenium compounds as mimics of selenoproteins and thiol modifier agents

scientific article published on 23 November 2017

Organotellurium and organoselenium compounds attenuate Mn-induced toxicity in Caenorhabditis elegans by preventing oxidative stress.

scientific article published on 8 March 2012

Organotins in obesity and associated metabolic disturbances

scientific article published on 08 November 2018

Overview of the effects of chemical mixtures with endocrine disrupting activity in the context of real-life risk simulation: An integrative approach (Review)

scientific article published on 01 July 2019

Oxidative Stress in Methylmercury-Induced Cell Toxicity

scientific article published on 09 August 2018

Oxidative damage and neurodegeneration in manganese-induced neurotoxicity

scientific article published on 14 July 2009

Oxidative stress in MeHg-induced neurotoxicity

scientific article

Oxidative stress is induced in the rat brain following repeated inhalation exposure to manganese sulfate.

scientific article published in January 2003

Oxidative stress mechanisms underlying Parkinson's disease-associated neurodegeneration in C. elegans

scientific article

Oxidative stress, caspase-3 activation and cleavage of ROCK-1 play an essential role in MeHg-induced cell death in primary astroglial cells

scientific article published on 8 February 2018

PAH Particles Perturb Prenatal Processes and Phenotypes: Protection from Deficits in Object Discrimination Afforded by Dampening of Brain Oxidoreductase Following In Utero Exposure to Inhaled Benzo(a)pyrene

scientific article published on October 10, 2011

Paraoxonase-1 Genetic Polymorphisms in Organophosphate Metabolism

scientific article published on 22 October 2018

Parenteral nutrition as an unexpected and preventable source of mercury exposure in preterm infants

scientific article published on 24 March 2015

Particulate Matter in Human Elderly: Higher Susceptibility to Cognitive Decline and Age-Related Diseases

scientific article published in 2023

Pathophysiology of manganese-associated neurotoxicity

scientific article published on December 21, 2011

Peaceful use of disastrous neurotoxicants

scientific article published on 08 July 2010

Persistent alterations in biomarkers of oxidative stress resulting from combined in utero and neonatal manganese inhalation

scientific article published in May 2005

Peumus boldus attenuates copper-induced toxicity in Drosophila melanogaster

scientific article published on 25 October 2017

Pharmacologic suppression of oxidative damage and dendritic degeneration following kainic acid-induced excitotoxicity in mouse cerebrum

scientific article published on 29 April 2008

Pharmacological characterization of swelling-induced d-[3H]aspartate release from primary astrocyte cultures

scientific article published on 01 June 1998

Pharmacology and toxicology of astrocyte-neuron glutamate transport and cycling

scientific article

Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell signaling in a murine striatal cell line

scientific article

Plant components can reduce methylmercury toxication: A mini-review

scientific article published on 06 March 2019

Plumbagin attenuates traumatic tracheal stenosis in rats and inhibits lung fibroblast proliferation and differentiation via TGF-β1/Smad and Akt/mTOR pathways

scientific article published on 01 December 2021

Polymorphic ventricular tachycardia and abnormal Ca2+ handling in very-long-chain acyl-CoA dehydrogenase null mice

scientific article published on 05 January 2007

Polyphenols in the treatment of autoimmune diseases

scientific article published on 03 May 2019

Post-translational modifications in MeHg-induced neurotoxicity

scientific article published on 29 October 2018

Potassium and taurine release are highly correlated with regulatory volume decrease in neonatal primary rat astrocyte cultures

scientific article published on 01 September 1994

Preconditioning of endoplasmic reticulum stress protects against acrylonitrile-induced cytotoxicity in primary rat astrocytes: The role of autophagy

scientific article published on 31 May 2016

Prenatal Polycyclic Aromatic Hydrocarbon Exposure Leads to Behavioral Deficits and Downregulation of Receptor Tyrosine Kinase, MET

scientific article published on October 1, 2010

Prenatal exposure to benzo(a)pyrene impairs later-life cortical neuronal function

scientific article

Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain.

scientific article

Progression of neurodegeneration and morphologic changes in the brains of juvenile mice with selenoprotein P deleted

scientific article published on May 5, 2011

Prolactin is a peripheral marker of manganese neurotoxicity.

scientific article

Prolonged hypoxia augments L-citrulline transport by system A in the newborn piglet pulmonary circulation.

scientific article

Prostanoid signaling: Dual role for prostaglandin E2 in neurotoxicity

scientific article published on March 3, 2011

Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist

scientific article published on 14 July 2009

Protective effect of Melissa officinalis aqueous extract against Mn-induced oxidative stress in chronically exposed mice

scientific article published on 15 October 2011

Protective effect of a novel peptide against methylmercury-induced toxicity in rat primary astrocytes.

scientific article published on 14 December 2011

Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative damage and neuronal injury

scientific article published on June 13, 2011

Protective effects of ebselen (Ebs) and para-aminosalicylic acid (PAS) against manganese (Mn)-induced neurotoxicity

scientific article published on December 9, 2011

Protective effects of novel organic selenium compounds against oxidative stress in the nematode Caenorhabditis elegans

scientific article

Protective effects of para-aminosalicylic acid (PAS) against manganese (Mn)-induced neurotoxicity

scholarly article by A.P. Marreilha dos Santos et al published August 2013 in Toxicology Letters

Putative proteins involved in manganese transport across the blood-brain barrier

scientific article published on April 2007

Quantification of Glutathione in Caenorhabditis elegans

scientific article published on May 2015

Quinolinic acid and glutamatergic neurodegeneration in Caenorhabditis elegans

scientific article published on 24 April 2018

RNASeq in C. elegans Following Manganese Exposure

scientific article

Rat brain endothelial cells are a target of manganese toxicity

scientific article

Re: Blood levels of mercury are related to diagnosis of autism: a reanalysis of an important data set.

scientific article published in April 2008

Recent Advances in Mercury Research

scientific article

Redox toxicology of environmental chemicals causing oxidative stress

scientific article published on 18 April 2020

Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model

scientific article published on 14 February 2017

Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.

scientific article

Repeated exposure to Ochratoxin A generates a neuroinflammatory response, characterized by neurodegenerative M1 microglial phenotype

scientific article published on 2 May 2014

Resistance of mouse primary microglia and astrocytes to acrylonitrile-induced oxidative stress

scientific article

Revelations from the Nematode Caenorhabditis elegans on the Complex Interplay of Metal Toxicological Mechanisms

scientific article

Reversible reprotoxic effects of manganese through DAF-16 transcription factor activation and vitellogenin downregulation in Caenorhabditis elegans.

scientific article published on 10 March 2016

Role for calcium signaling in manganese neurotoxicity

scientific article published on 22 August 2019

Role of Astrocytes in Manganese Neurotoxicity Revisited

scientific article published on 30 September 2019

Role of Caenorhabditis elegans AKT-1/2 and SGK-1 in Manganese Toxicity

scientific article published on 07 June 2018

Role of astrocytes in brain function and disease

scientific article

Role of astrocytes in manganese mediated neurotoxicity

scientific article

Role of autophagy in methylmercury-induced neurotoxicity in rat primary astrocytes

scientific article published on 09 December 2014

Role of docosahexaenoic acid in modulating methylmercury-induced neurotoxicity

scientific article published on 29 August 2007

Role of glutathione in determining the differential sensitivity between the cortical and cerebellar regions towards mercury-induced oxidative stress

scientific article published on 19 November 2006

Role of manganese in neurodegenerative diseases

scientific article published on October 2011

Role of matrix metalloproteinase-2/9 (MMP2/9) in lead-induced changes in an in vitro blood-brain barrier model

scientific article published on 31 October 2017

Role of transcription factor yin yang 1 in manganese-induced reduction of astrocytic glutamate transporters: Putative mechanism for manganese-induced neurotoxicity

scientific article

Roles of glia in developmental neurotoxicity: session VI summary and research needs

journal article published in 2001

Roles of glutamine in neurotransmission.

scientific article

SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity

scientific journal article

SLC30A10 transporter in the digestive system regulates brain manganese under basal conditions while brain SLC30A10 protects against neurotoxicity

scientific article published on 17 December 2018

SLC30A10: A novel manganese transporter

scientific article

SMF-1, SMF-2 and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese levels in C. elegans

scientific article

Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7.

scientific article

Selective vulnerability of dopaminergic systems to Manganese: Relevance to occupational exposure

scholarly article by Jeannette Stankowski et al published May 2008 in Neurotoxicology and Teratology

Selenium and Selenoproteins in Adipose Tissue Physiology and Obesity

scientific article published on 24 April 2020

Selenium species-dependent toxicity, bioavailability and metabolic transformations in Caenorhabditis elegans.

scientific article

Selenium, Zinc, Chromium, and Vanadium Levels in Serum, Hair, and Urine Samples of Obese Adults Assessed by Inductively Coupled Plasma Mass Spectrometry

scientific article published on 23 May 2020

Seleno- and telluro-xylofuranosides attenuate Mn-induced toxicity in C. elegans via the DAF-16/FOXO pathway.

scientific article published in December 2013

Selenoneine ameliorates peroxide-induced oxidative stress in C. elegans

scientific article published on 31 May 2019

Setting safer exposure limits for toxic substance combinations

scientific article published on 22 April 2020

Sex- and structure-specific differences in antioxidant responses to methylmercury during early development

scientific article published on 22 July 2016

Sex-Specific Differences in Redox Homeostasis in Brain Norm and Disease

scientific article published on 02 January 2019

Sex-Specific Response of Caenorhabditis elegans to Methylmercury Toxicity

scientific article published on 28 August 2018

Simultaneous exposure to vinylcyclohexene and methylmercury in Drosophila melanogaster: biochemical and molecular analyses

scientific article published on 19 December 2019

Small Molecule Modifiers of In Vitro Manganese Transport Alter Toxicity In Vivo

scientific article published on 28 September 2018

Smoking and DNA methylation: Correlation of methylation with smoking behavior and association with diseases and fetus development following prenatal exposure

scientific article published on 04 May 2019

Smoking is associated with altered serum and hair essential metal and metalloid levels in women

scientific article published on 18 June 2022

Sodium P-aminosalicylic Acid Inhibits Manganese-Induced Neuroinflammation in BV2 Microglial Cells via NLRP3-CASP1 Inflammasome Pathway

scientific article published on 06 November 2020

Sodium P-aminosalicylic acid inhibits sub-chronic manganese-induced neuroinflammation in rats by modulating MAPK and COX-2.

scientific article

Sodium-coupled neutral amino acid transporter 1 (SNAT1) modulates L-citrulline transport and nitric oxide (NO) signaling in piglet pulmonary arterial endothelial cells

scientific article published on 15 January 2014

Speciation of manganese in cells and mitochondria: a search for the proximal cause of manganese neurotoxicity

scientific article published on 7 May 2006

Stimulation of D-aspartate efflux by mercuric chloride from rat primary astrocyte cultures

scientific article published on 01 October 1993

Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and longevity regulation in Caenorhabditis elegans

scientific journal article

Structural Elements in the Transmembrane and Cytoplasmic Domains of the Metal Transporter SLC30A10 Are Required for Its Manganese Efflux Activity

scientific article published on 15 June 2016

Structure-activity relationship of flavonoids derived from medicinal plants in preventing methylmercury-induced mitochondrial dysfunction.

scientific article

Suppression of PTPN6 exacerbates aluminum oxide nanoparticle-induced COPD-like lesions in mice through activation of STAT pathway

scientific article published on 12 December 2017

SyM-BBB: a microfluidic Blood Brain Barrier model

scientific article published on March 2013

Synergistic neurotoxicity induced by methylmercury and quercetin in mice

scientific article

System-specific neurodegeneration following glucotoxicity in the C. elegans model

scientific article published on 20 July 2018

Targeted Metabolomic Analysis of Serum Fatty Acids for the Prediction of Autoimmune Diseases

scientific article published on 01 November 2019

Taurine ameliorates particulate matter-induced emphysema by switching on mitochondrial NADH dehydrogenase genes

scientific article

Thallium Toxicity in Caenorhabditis elegans: Involvement of the SKN-1 Pathway and Protection by S-Allylcysteine

scientific article published on 28 May 2020

The Caenorhabiditis elegans model as a reliable tool in neurotoxicology

scientific article published on 09 December 2010

The Neuron-Glia Unit in Neuropathology: Is it a Double-Edged Sword?

scientific article published on 01 January 2003

The Role of Autophagy Dysregulation in Manganese-Induced Dopaminergic Neurodegeneration

scientific article published on April 19, 2013

The Role of MicroRNAs in Patients with Amyotrophic Lateral Sclerosis

scientific article published on 10 November 2018

The Role of skn-1 in methylmercury-induced latent dopaminergic neurodegeneration

scientific article

The acute effects of acrylamide on astrocyte functions

scientific article

The aging brain: impact of heavy metal neurotoxicity

scientific article published on 19 November 2020

The catecholaminergic neurotransmitter system in methylmercury-induced neurotoxicity

scientific article published on 01 September 2017

The consequences of methylmercury exposure on interactive functions between astrocytes and neurons

scientific article

The cytoplasmic thioredoxin system in Caenorhabditis elegans affords protection from methylmercury in an age-specific manner

scientific article published on 20 August 2018

The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure

scientific article published on 08 July 2019

The effects of manganese on glutamate, dopamine and gamma-aminobutyric acid regulation.

scientific article

The effects of manganese overexposure on brain health

scientific article published on 20 January 2020

The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans

scientific article published on 22 January 2014

The impact of obesity on brain iron levels and α-synuclein expression is regionally dependent

scientific article published on 16 October 2017

The importance of glutamate, glycine, and gamma-aminobutyric acid transport and regulation in manganese, mercury and lead neurotoxicity

scientific article

The in vitro effects of Trolox on methylmercury-induced neurotoxicity

scientific article published on 15 July 2010

The in vitro effects of selenomethionine on methylmercury-induced neurotoxicity

scientific article

The in vitro uptake of glutamate in GLAST and GLT-1 transfected mutant CHO-K1 cells is inhibited by manganese

scientific article published on December 2005

The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and neuroinflammation in the rat brain

scientific article published on 3 December 2011

The interaction between microglia and neural stem/precursor cells

scientific article published on 22 September 2014

The methylmercury-L-cysteine conjugate is a substrate for the L-type large neutral amino acid transporter

scientific article published on 13 September 2008

The role of MT in neurological disorders.

scientific article published in November 2005

The role of NLRP3-CASP1 in inflammasome-mediated neuroinflammation and autophagy dysfunction in manganese-induced, hippocampal-dependent impairment of learning and memory ability

scientific article published on 27 February 2017

The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics

scientific article published on 06 March 2019

The role of poly(ADP-ribose) polymerases in manganese exposed Caenorhabditis elegans

scientific article published on 14 September 2019

The role of posttranslational modifications of α-synuclein and LRRK2 in Parkinson's disease: Potential contributions of environmental factors

scientific article published on 24 November 2018

The role of sulfhydryl groups and calcium in the mercuric chloride-induced inhibition of glutamate uptake in rat primary astrocyte cultures.

scientific article

The transcription factor REST up-regulates tyrosine hydroxylase and antiapoptotic genes and protects dopaminergic neurons against manganese toxicity

scientific article published on 30 January 2020

The transport of manganese across the blood-brain barrier

scientific article

The uptake of manganese in brain endothelial cultures

scientific article published in July 2002

The use of fluorescence for detecting MeHg-induced ROS in cell cultures.

scientific article

The use of magnetic resonance imaging (MRI) in the study of manganese neurotoxicity

scientific article

Therapeutic Efficacy of the N,N' Bis-(2-Mercaptoethyl) Isophthalamide Chelator for Methylmercury Intoxication in Caenorhabditis elegans

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Therapeutic potential of naringin in neurological disorders

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Thyroid hormones and methylmercury toxicity

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Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese

scientific article published on 23 January 2017

Toxicity of Organometal(loids)

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Toxicity of three types of arsenolipids: species-specific effects in Caenorhabditis elegans

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Toxicity studies on depleted uranium in primary rat cortical neurons and in Caenorhabditis elegans: what have we learned?

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Toxicogenomics in non-mammalian species—Editorial

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Toxicology of Lead and Its Damage to Mammalian Organs

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Toxicology of alkylmercury compounds

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Transcriptional Regulation of Human Transforming Growth Factor-α in Astrocytes.

scientific article published on 21 January 2016

Transcriptional Regulation of the Astrocytic Excitatory Amino Acid Transporter 1 (EAAT1) via NF-κB and Yin Yang 1 (YY1).

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Transcriptomic and Proteomic Tools in the Study of Hg Toxicity: What Is Missing?

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Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes

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Translational biomarkers of neurotoxicity: a Health and Environmental Sciences Institute perspective on the way forward

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Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems

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Triclosan induces PC12 cells injury is accompanied by inhibition of AKT/mTOR and activation of p38 pathway

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Tyrosine hydroxylase regulation in adult rat striatum following short-term neonatal exposure to manganese

scientific article published on 21 January 2016

Unmasking silent neurotoxicity following developmental exposure to environmental toxicants

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Untangling the Manganese-α-Synuclein Web

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Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status

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Upholding science in health, safety and environmental risk assessments and regulations

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Urinary delta-ALA: a potential biomarker of exposure and neurotoxic effect in rats co-treated with a mixture of lead, arsenic and manganese

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Use of microarray technologies in toxicology research.

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Utility of Caenorhabditis elegans in high throughput neurotoxicological research

scientific article published on 07 December 2008

Valproate and sodium butyrate attenuate manganese-decreased locomotor activity and astrocytic glutamate transporters expression in mice

scientific article published on 10 June 2017

Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity

scientific article published on 18 May 2018

Volume Measurements in Cultured Primary Astrocytes

scientific article published on January 1, 2011

XANES spectroscopy: a promising tool for toxicology: a tutorial

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XRCC1 mediated the development of cervival cancer through a novel Sp1/Krox-20 swich

scientific article published on 16 September 2017

Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes

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Zinc and respiratory tract infections: Perspectives for COVID‑19 (Review)

scientific article published on 14 April 2020

Zinc, copper, iron, and selenium levels in brain and liver of mice exposed to acrylonitrile

scientific article published on 23 January 2009

Zn homeostasis in genetic models of Parkinson's disease in Caenorhabditis elegans

scientific article published on 29 May 2019

cAMP Response Element-binding Protein (CREB) and Nuclear Factor κB Mediate the Tamoxifen-induced Up-regulation of Glutamate Transporter 1 (GLT-1) in Rat Astrocytes

scientific article published on August 16, 2013

trans-10,cis-12-Conjugated linoleic acid instigates inflammation in human adipocytes compared with preadipocytes

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γ-Glutamylcysteine ameliorates oxidative injury in neurons and astrocytes in vitro and increases brain glutathione in vivo.

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