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List of works by Samantha Perez-Miller

(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5.

scientific article published on 7 April 2015

A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B).

scientific article published on 6 September 2018

A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.

scientific article

Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant

scientific article

Antihypertensive drug treatment and susceptibility to SARS-CoV-2 infection in human PSC-derived cardiomyocytes and primary endothelial cells

scientific article published on 01 September 2021

Catalytic contribution of threonine 244 in human ALDH2

scientific article

Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels

scientific article published on 06 August 2018

Comparison of quinazoline and benzoylpyrazoline chemotypes targeting the CaVα-β interaction as antagonists of the N-type CaV2.2 channel

scientific article published on 01 December 2021

Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases

scientific article

Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.

scientific article published on 5 February 2017

In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike protein

scientific article published on 23 September 2020

Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain

scientific article published on 01 October 2018

Light chain C-terminal region reinforces the stability of clathrin heavy chain trimers

scientific article published on 06 June 2007

SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia

scientific article published on 24 August 2020

Small Molecule Targeting TDP-43's RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)

scientific article published on 27 August 2019

Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy

scientific article published on 01 July 2019

The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels

scientific article published on 21 November 2019

Three-dimensional structures of the three human class I alcohol dehydrogenases

scientific article

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