Search filters

List of works by Charles H Adler

3‐hydroxykynurenine and other Parkinson's disease biomarkers discovered by metabolomic analysis ⬇️

scientific article published on July 19, 2013

A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit

scientific article published on May 2014

Abnormal corticomuscular coherence is associated with the small amplitude cortical myoclonus in Parkinson's disease ⬇️

scientific article published on October 1, 2003

Abolishing the 1-year rule: How much evidence will be enough?

scientific article published on 26 September 2016

Adaptation to changes in vertical display gain during handwriting in Parkinson's disease patients, elderly and young controls

scientific article published in December 2002

Advances in Biomarker Research in Parkinson's Disease

scientific article published on January 2016

Alpha-Synuclein Pathology and Axonal Degeneration of the Peripheral Motor Nerves Innervating Pharyngeal Muscles in Parkinson Disease ⬇️

scientific article published on February 1, 2013

Alpha-Synuclein Pathology in Sensory Nerve Terminals of the Upper Aerodigestive Tract of Parkinson's Disease Patients

scientific article published on 4 June 2015

Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases

scientific article

Altered Pharyngeal Muscles in Parkinson Disease ⬇️

scientific article published on June 1, 2012

Altered aiming movements in Parkinson's disease patients and elderly adults as a function of delays in movement onset

scientific article

Amantadine in advanced Parkinson's disease: good use of an old drug.

scholarly article by Charles H Adler et al published 1997 in Journal of Neurology

Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease

scientific article published on January 2009

Analysis of high-frequency electroencephalographic-electromyographic coherence elicited by speech and oral nonspeech tasks in Parkinson's disease

scientific article published in April 2006

Are Clinical Certainty Ratings Helpful in the Diagnosis of Parkinson's Disease?

scholarly article by Harsh V Gupta et al published 22 February 2018 in Movement disorders clinical practice

Are there differences in cerebral white matter lesion burdens between Parkinson's disease patients with or without dementia?

scientific article

Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program

scientific article

Assessing medication role on neuropathological findings in Parkinson's disease

scientific article published on 16 February 2016

Association Between Pathology and Electroencephalographic Activity in Parkinson's Disease

scientific article published in February 2017

Autonomic complaints in patients with restless legs syndrome

scientific article

Autonomic function, as self-reported on the SCOPA-autonomic questionnaire, is normal in essential tremor but not in Parkinson's disease ⬇️

scientific article published on July 6, 2012

Bid signal pathway components are identified in the temporal cortex with Parkinson disease ⬇️

scientific article published on September 26, 2012

Biochemical Increase in Phosphorylated Alpha‐Synuclein Precedes Histopathology of Lewy‐Type Synucleinopathies ⬇️

scientific article published on April 12, 2012

Blinded RT-QuIC Analysis of α-Synuclein Biomarker in Skin Tissue from Parkinson's Disease Patients

scientific article published on 22 September 2020

Botulinum toxin type A for treating voice tremor

scientific article published in September 2004

Botulinum toxin type B (Myobloc) in subjects with hemifacial spasm: results from an open-label, dose-escalation safety study

scientific article published in July 2007

Brain biochemistry in autopsied patients with essential tremor

scientific article published on 28 October 2011

Case series of painful legs and moving toes: clinical and electrophysiologic observations

scientific article published on October 2008

Case studies in movement disorders

scientific article published in September 2003

Cerebrospinal fluid biomarkers of neuropathologically diagnosed Parkinson’s disease subjects ⬇️

scientific article published on September 1, 2012

Cervical dystonia and pain: characteristics and treatment patterns from CD PROBE (Cervical Dystonia Patient Registry for Observation of OnabotulinumtoxinA Efficacy)

scientific article

Changes in CD200 and intercellular adhesion molecule-1 (ICAM-1) levels in brains of Lewy body disorder cases are associated with amounts of Alzheimer's pathology not α-synuclein pathology

scientific article published on 16 March 2017

Changes in properties of serine 129 phosphorylated α-synuclein with progression of Lewy-type histopathology in human brains

scientific article

Cholesterol, copper and Abeta in controls, MCI, AD and the AD cholesterol-lowering treatment trial (ADCLT).

scientific article published in December 2005

Clinical Features of Patients with Concomitant Parkinson's Disease and Progressive Supranuclear Palsy Pathology

scientific article published on 29 October 2014

Clinical features, with video documentation, of the original familial lewy body parkinsonism caused by α-synuclein triplication (Iowa kindred).

scientific article

Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials

scientific article

Clinicopathological outcomes of prospectively followed normal elderly brain bank volunteers

scientific article

Comparison of neuropathology in Parkinson's disease subjects with and without deep brain stimulation

scientific article published on 2 December 2016

Concomitant pathologies among a spectrum of parkinsonian disorders

scientific article (publication date: May 2014)

Consensus-Based Attributes for Identifying Patients With Spasmodic Dysphonia and Other Voice Disorders

Contrast Acuity With Different Colors in Parkinson's Disease

scientific article published on 06 September 2019

Converging mediators from immune and trophic pathways to identify Parkinson disease dementia

scientific article published on 27 January 2016

Correlation of clinical features with argyrophilic grains at autopsy

scientific article published on July 2009

Cortical phosphorylated α-Synuclein levels correlate with brain wave spectra in Parkinson's disease

scientific article published on 08 April 2016

Corticomuscular coherence is increased in the small postural tremor of Parkinson's disease

scientific article published in April 2006

Defining mild cognitive impairment in Parkinson's disease

scientific article published in July 2007

Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson's disease

scholarly article by Isabel Ortuño-Lizarán et al published 10 September 2018 in Acta neuropathologica communications

Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines

scientific article published on 24 January 2012

Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients

scientific article published on 15 July 2009

Disease duration and the integrity of the nigrostriatal system in Parkinson's disease

scientific article published on August 2013

Does Parkinson's disease start in the gut?

scientific article published on 16 October 2017

Dysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodies

scientific article published on 07 September 2016

Effective treatment of orthostatic tremor with gabapentin ⬇️

scientific article published on September 1, 1998

Efficacy of rivastigmine for cognitive symptoms in Parkinson disease with dementia.

scientific article published in July 2009

Essential Tremor in the Elderly and Risk for Dementia

scientific article published on 9 April 2014

Essential Tremor is Not a Neurodegenerative Disease ⬇️

scientific article published on June 1, 2012

Essential tremor and Parkinson's disease: Lack of a link ⬇️

scientific article published on January 31, 2011

Essential tremor is not associated with cerebellar Purkinje cell loss

scientific article published on 15 February 2014

Evaluation of alpha-synuclein immunohistochemical methods used by invited experts

scientific article

Faster Cognitive Decline in Dementia due to Alzheimer Disease with Clinically Undiagnosed Lewy Body Disease

Feasibility Study: Comparison of Frontal Cortex Needle Core Versus Open Biopsy for Detection of Characteristic Proteinopathies of Neurodegenerative Diseases

scientific article

Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson's Disease: The Systemic Synuclein Sampling Study (S4)

scholarly article by Lana M Chahine et al published 2018 in Journal of Parkinson's disease

Feasibility of repeat and bilateral submandibular gland needle biopsies in Parkinson's disease

scientific article published on 07 October 2019

GBA mutations in Parkinson disease: earlier death but similar neuropathological features.

scientific article

GCH1 in early-onset Parkinson's disease.

scientific article

Gambling and increased sexual desire with dopaminergic medications in restless legs syndrome

scientific article

Gender Differences in Alzheimer Disease: Brain Atrophy, Histopathology Burden, and Cognition

scientific article published on 12 June 2016

Genetics of restless legs syndrome

scientific article

Genomic investigation of alpha-synuclein multiplication and parkinsonism

scientific article published on June 2008

Graph theory network function in Parkinson's disease assessed with electroencephalography

scientific article published on 4 March 2016

Heterogeneous neuropathological findings in Parkinson’s disease with mild cognitive impairment ⬇️

scientific article published on September 14, 2010

Hippocampal sclerosis dementia with tauopathy.

scientific article

Hypermethylation of Synphilin-1, Alpha-Synuclein-Interacting Protein (SNCAIP) Gene in the Cerebral Cortex of Patients with Sporadic Parkinson's Disease

scientific article published on 27 June 2017

Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms

scientific article published on 8 March 2007

Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4)

Impact of Cervical Dystonia on Work Productivity: An Analysis From a Patient Registry

scientific article published on 16 December 2015

Importance of low diagnostic Accuracy for early Parkinson's disease

scientific article published on 04 October 2018

Improved diagnosis of Parkinson's disease from a detailed olfactory phenotype

scientific article published on 8 September 2017

Incidental Lewy body disease: Electrophysiological findings suggesting pre-clinical Lewy body disorders ⬇️

scientific article published on May 26, 2011

Incidental Lewy body disease: clinical comparison to a control cohort

scientific article

Increased CSF biomarkers of angiogenesis in Parkinson disease

scientific article published on 28 October 2015

Knowledge gaps and research recommendations for essential tremor

scientific article

Lewy bodies are incidental in essential tremor

scientific article published on 3 March 2016

Lewy bodies in essential tremor are no different than in controls

scientific article published on 24 November 2015

Longitudinal EEG changes correlate with cognitive measure deterioration in Parkinson's disease

scientific article published on January 2015

Low clinical diagnostic accuracy of early vs advanced Parkinson disease: clinicopathologic study

scientific article

MDS Task Force on mild cognitive impairment in Parkinson's disease: critical review of PD-MCI.

scientific article

MDS clinical diagnostic criteria for Parkinson's disease

scientific article

MDS research criteria for prodromal Parkinson's disease

scientific article

Marked microglial reaction in normal aging human substantia nigra: correlation with extraneuronal neuromelanin pigment deposits

scientific article

Mild cognitive impairment as a risk factor for Parkinson's disease dementia

scientific article published on 12 June 2017

Minimal clinically important change in patients with cervical dystonia: Results from the CD PROBE study

scientific article published on 27 July 2019

Motor impairment in normal aging, clinically possible Parkinson's disease, and clinically probable Parkinson's disease: longitudinal evaluation of a cohort of prospective brain donors

scientific article published in December 2002

Movement disorder society criteria for clinically established early Parkinson's disease

scholarly article by Daniela Berg et al published 25 August 2018 in Movement Disorders

Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders

scientific article

Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson's Disease and Control Subjects

scientific article published on 31 August 2016

Multicenter observational study of abobotulinumtoxinA neurotoxin in cervical dystonia: The ANCHOR-CD registry

scientific article published on 21 February 2017

Myoclonus in Lewy body disorders.

scientific article published in January 2002

Neuronal gene expression correlates of Parkinson's disease with dementia

scientific article published on August 2008

Neuropathological Findings in Parkinson's Disease With Mild Cognitive Impairment

scientific article published on 08 February 2020

Neuropathological basis of nonmotor manifestations of Parkinson's disease

scientific article published on 31 March 2016

Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment

scientific article published on 20 August 2015

Neuropathological findings of PSP in the elderly without clinical PSP: Possible incidental PSP? ⬇️

scientific article published on March 21, 2011

Neuropathology of primary restless leg syndrome: absence of specific tau- and alpha-synuclein pathology

scientific article published in June 2004

Next-generation profiling to identify the molecular etiology of Parkinson dementia

scientific article published on 24 May 2016

No evidence for cognitive dysfunction or depression in patients with mild restless legs syndrome

scientific article

Nonmotor complications in Parkinson's disease

scientific article

Olfaction in the elderly: a cross-sectional analysis comparing Parkinson's disease with controls and other disorders

scientific article published in January 2010

Olfactory bulb alpha-synucleinopathy has high specificity and sensitivity for Lewy body disorders

scientific article

Olfactory dysfunction in incidental Lewy body disease and Parkinson's disease

scientific article published on 16 August 2014

Olfactory function in restless legs syndrome ⬇️

scientific article published on May 1, 1998

PET imaging of amyloid with Florbetapir F 18 and PET imaging of dopamine degeneration with 18F-AV-133 (florbenazine) in patients with Alzheimer's disease and Lewy body disorders

scientific article

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease

scientific article

Paraneoplastic chorea associated with CRMP-5 neuronal antibody and lung carcinoma

scientific article

Parkinson Disease Affects Peripheral Sensory Nerves in the Pharynx ⬇️

scientific article published on July 1, 2013

Parkinson disease and incidental Lewy body disease: Just a question of time?

scientific article

Parkinson disease with dementia: comparing patients with and without Alzheimer pathology

scientific article published on July 2009

Parkinson's Disease Dementia and Potential Therapeutic Strategies ⬇️

scientific article published on December 28, 2010

Parkinson's Patients with Dyskinesia Switched from Immediate Release Amantadine to Open-label ADS-5102.

scientific article published on 23 February 2018

Parkinson's disease, cortical dysfunction, and alpha-synuclein

scientific article

Parkinsonism Reduces Coordination of Fingers, Wrist, and Arm in Fine Motor Control

scholarly article by Hans-Leo Teulings et al published July 1997 in Experimental Neurology

Parkinsonism, FXTAS, and FMR1 premutations

scientific article published in February 2005

Parkinson’s disease is not associated with gastrointestinal myenteric ganglion neuron loss ⬇️

scientific article published on September 2, 2012

Pathogenicity of the Lrrk2 R1514Q substitution in Parkinson's disease

scholarly article by Mathias Toft et al published 2007 in Movement Disorders

Pathological α-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology

scientific article published on 31 December 2015

Pathology in essential tremor ⬇️

scientific article published on January 1, 2012

Patient versus informant reporting of ICD symptoms in Parkinson’s disease using the QUIP: Validity and variability ⬇️

scientific article published on December 24, 2010

Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings

scientific article published on 22 January 2016

Phosphorylated α-synuclein in the retina is a biomarker of Parkinson's disease pathology severity

scientific article published on 08 May 2018

Phosphorylated α-synuclein-immunoreactive retinal neuronal elements in Parkinson's disease subjects

scientific article published on 28 April 2014

Placebo response in Parkinson's disease: comparisons among 11 trials covering medical and surgical interventions

scientific article

Plaques and tangles as well as Lewy-type alpha synucleinopathy are associated with formed visual hallucinations

scientific article

Premotor Symptoms and Early Diagnosis of Parkinson's Disease ⬇️

scientific article published on January 1, 2011

Presence of Striatal Amyloid Plaques in Parkinson's Disease Dementia Predicts Concomitant Alzheimer's Disease: Usefulness for Amyloid Imaging ⬇️

scientific article published on January 1, 2012

Prevalence of Submandibular Gland Synucleinopathy in Parkinson's Disease, Dementia with Lewy Bodies and other Lewy Body Disorders

scientific article

Primary results from the cervical dystonia patient registry for observation of onabotulinumtoxina efficacy (CD PROBE).

scientific article published on 27 December 2014

Probable RBD is increased in Parkinson’s disease but not in essential tremor or restless legs syndrome ⬇️

scientific article published on April 8, 2011

Probing the striatal dopamine system for a putative neuroprotective effect of deep brain stimulation in Parkinson's disease

scientific article published on 30 January 2018

Profiles of extracellular miRNA in cerebrospinal fluid and serum from patients with Alzheimer's and Parkinson's diseases correlate with disease status and features of pathology

scientific article

Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease

scientific article

Quantitative appraisal of ventricular cerebrospinal fluid biomarkers in neuropathologically diagnosed Parkinson's disease cases lacking Alzheimer's disease pathology

scientific article published on 12 March 2013

Quantitative measurement of intact alpha-synuclein proteoforms from post-mortem control and Parkinson's disease brain tissue by intact protein mass spectrometry

scientific article

REM sleep behavior disorder and neuropathology in Parkinson's disease

scientific article published on 12 August 2015

Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease

scientific article published in March 2003

Rationale and design of a prospective study: Cervical Dystonia Patient Registry for Observation of OnaBotulinumtoxinA Efficacy (CD PROBE) ⬇️

scientific article published on November 4, 2011

Reduced striatal tyrosine hydroxylase in incidental Lewy body disease

scientific article

Regional neuropathology distribution and verbal fluency impairments in Parkinson's disease

scientific article published on 10 May 2019

Relevance of motor complications in Parkinson's disease

scientific article

Reply: Purkinje cell loss in essential tremor

scientific article published in August 2014

Research priorities in spasmodic dysphonia

scientific article

Response to Parkinnen et al. and Jellinger

scientific article published on 3 December 2008

Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulation

scientific article published in August 2006

Risk of Parkinson's disease dementia related to level I MDS PD-MCI

scientific article published on 17 January 2019

Risperidone is effective in severe hemichorea/hemiballismus

scientific article published on 01 March 1999

Role for the microtubule-associated protein tau variant p.A152T in risk of α-synucleinopathies

scientific article

SMG1 identified as a regulator of Parkinson's disease-associated alpha-synuclein through siRNA screening

scientific article

Simplified conversion method for unified Parkinson's disease rating scale motor examinations

scientific article

Sleep issues in Parkinson's disease

scientific article

Slowing of number naming speed by King-Devick test in Parkinson's disease

scientific article published on 18 October 2013

Small-amplitude cortical myoclonus in Parkinson's disease: physiology and clinical observations

scientific article published in July 2002

Sniffing out Parkinson disease: can olfactory testing differentiate parkinsonian disorders?

scientific article published on November 2007

Submandibular Gland Biopsy for the Diagnosis of Parkinson Disease ⬇️

scientific article published on February 1, 2013

Submandibular gland needle biopsy for the diagnosis of Parkinson disease

scientific article published on 05 February 2014

The Montreal Cognitive Assessment and the mini-mental state examination as screening instruments for cognitive impairment: item analyses and threshold scores

scientific article published on 29 January 2011

The Search for a Peripheral Biopsy Indicator of α-Synuclein Pathology for Parkinson Disease

scientific article published on 9 January 2017

The Systemic Synuclein Sampling Study: toward a biomarker for Parkinson's disease

scientific article published on 29 March 2017

The neurobiological basis of cognitive impairment in Parkinson's disease

scientific article

The new definition and diagnostic criteria of Parkinson's disease

scientific article published on 11 April 2016

The patient with Parkinson's disease: part I-treating the motor symptoms; part II-treating the nonmotor symptoms

scientific article published on April 2007

Unified Staging System for Lewy Body Disorders: Clinicopathologic Correlations and Comparison to Braak Staging

scientific article published on 01 October 2019

Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction

scientific article published on 28 April 2009

Validation of the questionnaire for impulsive-compulsive disorders in Parkinson's disease

scientific article

Paulina is supported by:

About Paulina

Help