List of works - Lourdes Santana

1,2-disubstituted cyclohexane carbocyclic analogues of nucleosides.

scientific article published in April 2001

3-(4-Meth-oxy-benzo-yl)-6-nitro-coumarin.

scientific article published on 6 February 2013

3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases

scientific article published on 23 October 2015

3D QSAR Markov model for drug-induced eosinophilia--theoretical prediction and preliminary experimental assay of the antimicrobial drug G1

scientific article published on 01 March 2005

A QSAR model for in silico screening of MAO-A inhibitors. Prediction, synthesis, and biological assay of novel coumarins.

scientific article published in February 2006

A network-QSAR model for prediction of genetic-component biomarkers in human colorectal cancer

scientific article published on 03 August 2009

A new psoralen derivative with enlarged antiproliferative properties.

scientific article published on 24 March 2009

A novel approach for the virtual screening and rational design of anticancer compounds.

scientific article published in May 2000

AM1 theoretical study, synthesis and biological evaluation of some benzofuran analogues of anti-inflammatory arylalkanoic acids

scientific article published on 01 January 1999

ANN-QSAR model for selection of anticancer leads from structurally heterogeneous series of compounds.

scientific article published on 15 December 2006

Assignment of the1H and13C NMR signals of some benzofurocoumarins

scientific article published on 01 June 2006

Assignment of the1H and13C NMR signals of some hydroxyphenylcoumarins

scientific article published on 01 January 2007

Chalcone-based derivatives as new scaffolds for hA3 adenosine receptor antagonists

scientific article

Computational chemistry development of a unified free energy Markov model for the distribution of 1300 chemicals to 38 different environmental or biological systems.

scientific article published in August 2007

Coumarin derivatives as promising xanthine oxidase inhibitors

scientific article published on 03 September 2018

Development of novel adenosine receptor ligands based on the 3-amidocoumarin scaffold

scientific article published on 22 May 2015

Drug-drug interaction through molecular structure similarity analysis.

scientific article published on 30 May 2012

Evaluation of trypanocidal and antioxidant activities of a selected series of 3-amidocoumarins.

scientific article published on 18 April 2018

Hydroxycoumarins as selective MAO-B inhibitors

scientific article published on 11 November 2011

Improved Synthesis of 3-(Aminoaryl)coumarins

In silico genotoxicity of coumarins: application of the Phenol-Explorer food database to functional food science.

scientific article

Insight into the Functional and Structural Properties of 3-Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition

scientific article published on 08 April 2014

Insight into the interactions between novel coumarin derivatives and human A3 adenosine receptors

scientific article

Interest of antioxidant agents in parasitic diseases. The case study of coumarins.

scientific article

Ligand and Structure-based Modeling of Passive Diffusion through the Blood-Brain Barrier.

scientific article published on 6 November 2017

Looking for new targets: simple coumarins as antibacterial agents.

scientific article published in November 2012

MAO Inhibitory Activity of 2-Arylbenzofurans versus 3-Arylcoumarins: Synthesis, in vitro Study, and Docking Calculations

scientific article published on 15 April 2013

Markovian chemicals "in silico" design (MARCH-INSIDE), a promising approach for computer-aided molecular design I: discovery of anticancer compounds.

scientific article

Markovian chemicals "in silico" design (MARCH-INSIDE), a promising approach for computer-aided molecular design III: 2.5D indices for the discovery of antibacterials.

scientific article

Molecular Docking and Drug Discovery in β-Adrenergic Receptors

scientific article

Monoamino oxidase a: an interesting pharmacological target for the development of multi-target QSAR.

scientific article published on September 2012

N-(2-Oxo-2H-chromen-3-yl)cyclo-hexane-carboxamide.

scientific article published on 24 November 2012

Nanoparticles in the treatment of mental disorders: a new tool in the psychiatric medication.

scientific article published on January 2015

New Tetracyclic Analogues of Photochemotherapeutic Drugs 5-MOP and 8-MOP: Synthesis, DNA Interaction, and Antiproliferative Activity

scientific article published on 01 October 1999

New furan side tetracyclic allopsoralen derivatives: synthesis and photobiological evaluation.

scientific article published on July 2006

New halogenated phenylcoumarins as tyrosinase inhibitors

scientific article published on 09 April 2011

On the applicability of QSAR for recognition of miRNA bioorganic structures at early stages of organism and cell development: embryo and stem cells.

scientific article published on 2 February 2007

Phenylpiperazine derivatives with strong affinity for 5HT1A, D2A and D3 receptors

scientific article published on 01 December 1998

Potent and selective MAO-B inhibitory activity: Amino- versus nitro-3-arylcoumarin derivatives

scientific article published on 08 December 2014

Probabilistic neural network model for the in silico evaluation of anti-HIV activity and mechanism of action.

scientific article published in February 2006

Proteomics, networks and connectivity indices.

scientific article

Pyridazine Derivatives, VI. Synthesis and Hypotensive Activity of 3-Hydrazinethieno(2,3-h)Cinnoline and its Derivatives

scientific article published on 01 October 1988

Pyridazine Derivatives, VII. Synthesis and Hypotensive Activity of 3-Hydrazinocycloalkyl[1,2-c]pyridazines and their Derivatives

scientific article published on 01 June 1989

QSAR for anti-RNA-virus activity, synthesis, and assay of anti-RSV carbonucleosides given a unified representation of spectral moments, quadratic, and topologic indices.

scientific article published in March 2005

QSAR model for alignment-free prediction of human breast cancer biomarkers based on electrostatic potentials of protein pseudofolding HP-lattice networks

scientific article published on 01 December 2008

QSAR study of anticoccidial activity for diverse chemical compounds: prediction and experimental assay of trans-2-(2-nitrovinyl)furan

scientific article published on 19 October 2006

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

scientific article published on 4 October 2008

Scoring function for DNA-drug docking of anticancer and antiparasitic compounds based on spectral moments of 2D lattice graphs for molecular dynamics trajectories

scientific article published on 17 June 2009

Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity.

scientific article

Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists

scientific article published on 04 December 2019

Study of coumarin-resveratrol hybrids as potent antioxidant compounds.

scientific article

Symmetry considerations in Markovian chemicals 'in silico' design (MARCH-INSIDE) I: central chirality codification, classification of ACE inhibitors and prediction of sigma-receptor antagonist activities.

scientific article

Synthesis and Electrochemical and Biological Studies of Novel Coumarin–Chalcone Hybrid Compounds

scientific article published on 30 July 2013

Synthesis and adenosine receptors binding affinities of a series of 3-arylcoumarins

scientific article published on 22 August 2013

Synthesis and biological evaluation of 1,2-disubstituted carbonucleosides of 2-amino-6-substituted purine and 8-azapurine

scientific article published on 01 June 1998

Synthesis and complete assignment of the 1H and 13C NMR signals of some oxopyrancoumarin and oxofuropyrancoumarin derivatives.

scientific article published in July 2008

Synthesis and cytotoxic activity of non-naturally substituted 4-oxycoumarin derivatives.

scientific article published on 5 August 2012

Synthesis and evaluation of antioxidant and trypanocidal properties of a selected series of coumarin derivatives.

scientific article published on October 2013

Synthesis and structural study of pyrimidyl carbocyclic analogues of nucleosides based on cyclopentene rings.

scientific article published in April 2001

Synthesis and structure-activity relationships of novel amino/nitro substituted 3-arylcoumarins as antibacterial agents

scientific article published on 24 January 2013

Synthesis and vasorelaxant activity of new coumarin and furocoumarin derivatives.

scientific article published in March 2002

Synthesis and vasorelaxant and platelet antiaggregatory activities of a new series of 6-halo-3-phenylcoumarins

scientific article published on 12 January 2010

Synthesis, antioxidant and antichagasic properties of a selected series of hydroxy-3-arylcoumarins

scientific article published on 19 November 2016

Synthesis, biological evaluation and structure-activity relationships of new phthalazinedione derivatives with vasorelaxant activity.

scientific article

Synthesis, conformational analysis and antiviral and antitumoral activity of new 1,2-disubstituted carbocyclic nucleosides.

scientific article published in September 2002

Targeting adenosine receptors with coumarins: synthesis and binding activities of amide and carbamate derivatives

scientific article published in January 2013

Tyrosine-like condensed derivatives as tyrosinase inhibitors

scientific article published on 21 February 2012

Unified Markov thermodynamics based on stochastic forms to classify drugs considering molecular structure, partition system, and biological species: distribution of the antimicrobial G1 on rat tissues

scientific article published on 01 February 2005

Unified QSAR approach to antimicrobials. Part 2: predicting activity against more than 90 different species in order to halt antibacterial resistance.

scientific article published on 21 October 2006

Unify QSAR approach to antimicrobials. Part 1: predicting antifungal activity against different species.

scientific article published on 8 June 2006

List of works by Lourdes Santana

1,2-disubstituted cyclohexane carbocyclic analogues of nucleosides.

3-(4-Meth-oxy-benzo-yl)-6-nitro-coumarin.

3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases

3D QSAR Markov model for drug-induced eosinophilia--theoretical prediction and preliminary experimental assay of the antimicrobial drug G1

A QSAR model for in silico screening of MAO-A inhibitors. Prediction, synthesis, and biological assay of novel coumarins.

A network-QSAR model for prediction of genetic-component biomarkers in human colorectal cancer

A new psoralen derivative with enlarged antiproliferative properties.

A novel approach for the virtual screening and rational design of anticancer compounds.

AM1 theoretical study, synthesis and biological evaluation of some benzofuran analogues of anti-inflammatory arylalkanoic acids

ANN-QSAR model for selection of anticancer leads from structurally heterogeneous series of compounds.

Assignment of the1H and13C NMR signals of some benzofurocoumarins

Assignment of the1H and13C NMR signals of some hydroxyphenylcoumarins

Chalcone-based derivatives as new scaffolds for hA3 adenosine receptor antagonists

Computational chemistry development of a unified free energy Markov model for the distribution of 1300 chemicals to 38 different environmental or biological systems.

Coumarin derivatives as promising xanthine oxidase inhibitors

Development of novel adenosine receptor ligands based on the 3-amidocoumarin scaffold

Drug-drug interaction through molecular structure similarity analysis.

Evaluation of trypanocidal and antioxidant activities of a selected series of 3-amidocoumarins.

Hydroxycoumarins as selective MAO-B inhibitors

Improved Synthesis of 3-(Aminoaryl)coumarins

In silico genotoxicity of coumarins: application of the Phenol-Explorer food database to functional food science.

Insight into the Functional and Structural Properties of 3-Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition

Insight into the interactions between novel coumarin derivatives and human A3 adenosine receptors

Interest of antioxidant agents in parasitic diseases. The case study of coumarins.

Ligand and Structure-based Modeling of Passive Diffusion through the Blood-Brain Barrier.

Looking for new targets: simple coumarins as antibacterial agents.

MAO Inhibitory Activity of 2-Arylbenzofurans versus 3-Arylcoumarins: Synthesis, in vitro Study, and Docking Calculations

Markovian chemicals "in silico" design (MARCH-INSIDE), a promising approach for computer-aided molecular design I: discovery of anticancer compounds.

Markovian chemicals "in silico" design (MARCH-INSIDE), a promising approach for computer-aided molecular design III: 2.5D indices for the discovery of antibacterials.

Molecular Docking and Drug Discovery in β-Adrenergic Receptors

Monoamino oxidase a: an interesting pharmacological target for the development of multi-target QSAR.

N-(2-Oxo-2H-chromen-3-yl)cyclo-hexane-carboxamide.

Nanoparticles in the treatment of mental disorders: a new tool in the psychiatric medication.

New Tetracyclic Analogues of Photochemotherapeutic Drugs 5-MOP and 8-MOP: Synthesis, DNA Interaction, and Antiproliferative Activity

New furan side tetracyclic allopsoralen derivatives: synthesis and photobiological evaluation.

New halogenated phenylcoumarins as tyrosinase inhibitors

On the applicability of QSAR for recognition of miRNA bioorganic structures at early stages of organism and cell development: embryo and stem cells.

Phenylpiperazine derivatives with strong affinity for 5HT1A, D2A and D3 receptors

Potent and selective MAO-B inhibitory activity: Amino- versus nitro-3-arylcoumarin derivatives

Probabilistic neural network model for the in silico evaluation of anti-HIV activity and mechanism of action.

Proteomics, networks and connectivity indices.

Pyridazine Derivatives, VI. Synthesis and Hypotensive Activity of 3-Hydrazinethieno(2,3-h)Cinnoline and its Derivatives

Pyridazine Derivatives, VII. Synthesis and Hypotensive Activity of 3-Hydrazinocycloalkyl[1,2-c]pyridazines and their Derivatives

QSAR for anti-RNA-virus activity, synthesis, and assay of anti-RSV carbonucleosides given a unified representation of spectral moments, quadratic, and topologic indices.

QSAR model for alignment-free prediction of human breast cancer biomarkers based on electrostatic potentials of protein pseudofolding HP-lattice networks

QSAR study of anticoccidial activity for diverse chemical compounds: prediction and experimental assay of trans-2-(2-nitrovinyl)furan

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Scoring function for DNA-drug docking of anticancer and antiparasitic compounds based on spectral moments of 2D lattice graphs for molecular dynamics trajectories

Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity.

Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists

Study of coumarin-resveratrol hybrids as potent antioxidant compounds.

Symmetry considerations in Markovian chemicals 'in silico' design (MARCH-INSIDE) I: central chirality codification, classification of ACE inhibitors and prediction of sigma-receptor antagonist activities.

Synthesis and Electrochemical and Biological Studies of Novel Coumarin–Chalcone Hybrid Compounds

Synthesis and adenosine receptors binding affinities of a series of 3-arylcoumarins

Synthesis and biological evaluation of 1,2-disubstituted carbonucleosides of 2-amino-6-substituted purine and 8-azapurine

Synthesis and complete assignment of the 1H and 13C NMR signals of some oxopyrancoumarin and oxofuropyrancoumarin derivatives.

Synthesis and cytotoxic activity of non-naturally substituted 4-oxycoumarin derivatives.

Synthesis and evaluation of antioxidant and trypanocidal properties of a selected series of coumarin derivatives.

Synthesis and structural study of pyrimidyl carbocyclic analogues of nucleosides based on cyclopentene rings.

Synthesis and structure-activity relationships of novel amino/nitro substituted 3-arylcoumarins as antibacterial agents

Synthesis and vasorelaxant activity of new coumarin and furocoumarin derivatives.

Synthesis and vasorelaxant and platelet antiaggregatory activities of a new series of 6-halo-3-phenylcoumarins

Synthesis, antioxidant and antichagasic properties of a selected series of hydroxy-3-arylcoumarins

Synthesis, biological evaluation and structure-activity relationships of new phthalazinedione derivatives with vasorelaxant activity.

Synthesis, conformational analysis and antiviral and antitumoral activity of new 1,2-disubstituted carbocyclic nucleosides.

Targeting adenosine receptors with coumarins: synthesis and binding activities of amide and carbamate derivatives

Tyrosine-like condensed derivatives as tyrosinase inhibitors

Unified Markov thermodynamics based on stochastic forms to classify drugs considering molecular structure, partition system, and biological species: distribution of the antimicrobial G1 on rat tissues

Unified QSAR approach to antimicrobials. Part 2: predicting activity against more than 90 different species in order to halt antibacterial resistance.

Unify QSAR approach to antimicrobials. Part 1: predicting antifungal activity against different species.