List of works by Maxime Rousseaux

A Druggable Genome Screen Identifies Modifiers of α-Synuclein Levels via a Tiered Cross-Species Validation Approach

scientific article published on 24 September 2018

A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.

scientific article published on 19 May 2015

ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.

scientific article published on 7 March 2018

An Anatomically Resolved Mouse Brain Proteome Reveals Parkinson Disease-relevant Pathways.

scientific article published on 2 February 2017

Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes.

scientific article published on 17 December 2015

BAG2 Gene-mediated Regulation of PINK1 Protein Is Critical for Mitochondrial Translocation of PARKIN and Neuronal Survival

scientific article

CRISPRcloud: A secure cloud-based pipeline for CRISPR pooled screen deconvolution

scientific article published on 24 May 2017

DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress.

scientific article

DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway.

scientific article

Deep brain stimulation for Parkinson disease: the 2014 Lasker-DeBakey Clinical Medical Research Award.

scientific article published on March 2015

Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau.

scientific article

Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.

scientific article published on 13 March 2017

Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity

scientific article published on 20 November 2019

Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1

scientific article published on 11 March 2021

Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo.

scientific article

Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma

scientific article

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

scientific article

Regulation of the VHL/HIF-1 pathway by DJ-1

scientific article

Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease.

scientific article

The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage.

scholarly article

The role of TDP-43 mislocalization in amyotrophic lateral sclerosis

scientific article published on 15 August 2020

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