List of works - Abdelnaby Khalyfa

Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea

scientific article published on 8 June 2017

Adipose tissue macrophage polarization by intermittent hypoxia in a mouse model of OSA: effect of tumor microenvironment

scientific article published on 14 March 2015

Altered CD8+ T-Cell Lymphocyte Function and TC1 Cell Stemness Contribute to Enhanced Malignant Tumor Properties in Murine Models of Sleep Apnea

scientific article

Analysis of probe level patterns in Affymetrix microarray data

scientific article

Angiopoietin-2 and soluble Tie-2 receptor plasma levels in children with obstructive sleep apnea and obesity

scientific article published on 5 May 2017

Aorta macrophage inflammatory and epigenetic changes in a murine model of obstructive sleep apnea: Potential role of CD36.

scientific article published on 27 February 2017

Catecholamine alterations in pediatric obstructive sleep apnea: effect of obesity

scientific article published on June 2009

Changes in protein levels of elongation factors, eEF1A-1 and eEF1A-2/S1, in long-term denervated rat muscle

scientific article

Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice

scientific article published on 14 October 2016

Circulating Exosomal miRNAs Signal Circadian Misalignment to Peripheral Metabolic Tissues

scientific article published on 03 September 2020

Circulating Plasma Extracellular Microvesicle MicroRNA Cargo and Endothelial Dysfunction in Children with Obstructive Sleep Apnea

scientific article published on 10 May 2016

Circulating exosomes in obstructive sleep apnea as phenotypic biomarkers and mechanistic messengers of end-organ morbidity

scientific article published on July 2017

Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation

scientific article published on 13 July 2016

Circulating microRNAs as Potential Biomarkers of Endothelial Dysfunction in Obese Children

scientific article published on 13 August 2015

Circulating plasma exosomes in obstructive sleep apnoea and reverse dipping blood pressure

scientific article published on 30 January 2020

Cognitive function in prepubertal children with obstructive sleep apnea: a modifying role for NADPH oxidase p22 subunit gene polymorphisms?

scientific article published on 12 October 2011

DNA Methylation Profiling of Blood Monocytes in Patients With Obesity Hypoventilation Syndrome: Effect of Positive Airway Pressure Treatment

scientific article published on 25 February 2016

DNA methylation in inflammatory genes among children with obstructive sleep apnea

scientific article published on 10 November 2011

Development-dependent disappearance of caspase-3 in skeletal muscle is post-transcriptionally regulated

scientific article

Early intermittent hypoxia induces proatherogenic changes in aortic wall macrophages in a murine model of obstructive sleep apnea

scientific article published in October 2014

Early-life physical activity reverses metabolic and Foxo1 epigenetic misregulation induced by gestational sleep disturbance

scientific article

Effect on Intermittent Hypoxia on Plasma Exosomal Micro RNA Signature and Endothelial Function in Healthy Adults

scientific article published on 09 September 2016

Effects of long-term denervation on skeletal muscle in old rats

scientific journal article

Endothelial Dysfunction in Children With Obstructive Sleep Apnea Is Associated With Elevated Lipoprotein-Associated Phospholipase A2 Plasma Activity Levels

scientific article published on 9 February 2017

Endothelial dysfunction in children with obstructive sleep apnea is associated with epigenetic changes in the eNOS gene

scientific article

Erratum to “Transcription profiling of estrogen target genes in young and old mouse uterus” [Exp. Gerontol. 38 (2003) 1087–1099]

article

Evaluation of circulating markers of hepatic apoptosis and inflammation in obese children with and without obstructive sleep apnea

scientific article published on 29 May 2015

Exosomal miRNAs as potential biomarkers of cardiovascular risk in children

scientific article

Exosomes and Metabolic Function in Mice Exposed to Alternating Dark-Light Cycles Mimicking Night Shift Work Schedules

scientific article

Exosomes contribute to endothelial integrity and acute chest syndrome risk: Preliminary findings

scientific article published on 9 May 2017

Fatty-acid binding protein 4 gene polymorphisms and plasma levels in children with obstructive sleep apnea

scientific article

Fatty-acid binding protein 4 gene variants and childhood obesity: potential implications for insulin sensitivity and CRP levels

scientific article

Fragmented sleep accelerates tumor growth and progression through recruitment of tumor-associated macrophages and TLR4 signaling

scientific article

Genetic variance in nitric oxide synthase and endothelin genes among children with and without endothelial dysfunction

scientific article published on 25 September 2013

Genetics and Extracellular Vesicles of Pediatrics Sleep Disordered Breathing and Epilepsy ⬇️

scientific article published on 04 November 2019

Genome-wide gene expression profiling in children with non-obese obstructive sleep apnea

scientific article published on 7 February 2008

Human adult olfactory neuroepithelial derived progenitors retain telomerase activity and lack apoptotic activity

scientific article published in May 2005

Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3.

scientific article published on 12 April 2007

Insulin sensitivity, serum lipids, and systemic inflammatory markers in school-aged obese and nonobese children

scientific article

Integrated stress response activation by sleep fragmentation during late gestation in mice leads to emergence of adverse metabolic phenotype in offspring

scientific article published on 21 January 2017

Integrative miRNA-mRNA profiling of adipose tissue unravels transcriptional circuits induced by sleep fragmentation

scientific article

Intermittent hypoxia activates temporally coordinated transcriptional programs in visceral adipose tissue

scientific article published on 16 November 2011

Intermittent hypoxia causes NOX2-dependent remodeling of atrial connexins

scientific article

Intermittent hypoxia mobilizes bone marrow-derived very small embryonic-like stem cells and activates developmental transcriptional programs in mice

scientific article published in November 2010

Leukocyte telomere length and plasma catestatin and myeloid-related protein 8/14 concentrations in children with obstructive sleep apnea

scientific article

Lipopolysaccharide-binding protein plasma levels in children: effects of obstructive sleep apnea and obesity

scientific article

MPrime: efficient large scale multiple primer and oligonucleotide design for customized gene microarrays

scientific article

Macrophage migration inhibitory factor gene polymorphisms and plasma levels in children with obstructive sleep apnea

scientific article

Microarray reveals complement components are regulated in the serum-deprived rat retinal ganglion cell line

scientific article

Nitric oxide production by monocytes in children with OSA and endothelial dysfunction

scientific article

Obstructive sleep apnea and obesity are associated with reduced GPR 120 plasma levels in children

scientific article published on May 2014

Plasma Exosomes Disrupt Blood Brain Barrier in Children with OSA and Neurocognitive Deficits

scientific article

Plasma Exosomes and Improvements in Endothelial Function by Angiotensin 2 Type 1 Receptor or Cyclooxygenase 2 Blockade following Intermittent Hypoxia

scientific article published on 22 December 2017

Polymorphisms in nitric oxide synthase and endothelin genes among children with obstructive sleep apnea

scientific article

Prolonged Exposures to Intermittent Hypoxia Promote Visceral White Adipose Tissue Inflammation in a Murine Model of Severe Sleep Apnea: Effect of Normoxic Recovery

scientific article published on 22 December 2016

Protein-Tyrosine Phosphatase-1B Mediates Sleep Fragmentation-Induced Insulin Resistance and Visceral Adipose Tissue Inflammation in Mice

scientific article

Serum deprivation induces apoptotic cell death of transformed rat retinal ganglion cells via mitochondrial signaling pathways

scientific article

Sex dimorphism in late gestational sleep fragmentation and metabolic dysfunction in offspring mice

scientific article

Sleep fragmentation during late gestation induces metabolic perturbations and epigenetic changes in adiponectin gene expression in male adult offspring mice.

scientific article

Sleep fragmentation in mice induces nicotinamide adenine dinucleotide phosphate oxidase 2-dependent mobilization, proliferation, and differentiation of adipocyte progenitors in visceral white adipose tissue

scientific article published on May 2014

Sleep measures and morning plasma TNF-alpha levels in children with sleep-disordered breathing

scientific article

Stability of Circulating Exosomal miRNAs in Healthy Subjects.

scientific article published on 9 July 2018

TNF-α gene polymorphisms and excessive daytime sleepiness in pediatric obstructive sleep apnea

scientific article

Temporal trajectories of novel object recognition performance in mice exposed to intermittent hypoxia

scientific article published on 14 December 2017

The Challenges of Precision Medicine in Obstructive Sleep Apnea

scientific article published on 2 March 2016

Transcription profiling of estrogen target genes in young and old mouse uterus

scientific article published on October 2003

Transcriptional landscape of bone marrow-derived very small embryonic-like stem cells during hypoxia

scientific article published on 10 May 2011

Transcriptomic Changes of Murine Visceral Fat Exposed to Intermittent Hypoxia at Single Cell Resolution

scientific article published on 29 December 2020

Transcriptomic analysis identifies phosphatases as novel targets for adenotonsillar hypertrophy of pediatric obstructive sleep apnea

scientific article

Variants in C-reactive protein and IL-6 genes and susceptibility to obstructive sleep apnea in children: a candidate-gene association study in European American and Southeast European populations

scientific article published on 04 December 2013

List of works by Abdelnaby Khalyfa

Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea

Adipose tissue macrophage polarization by intermittent hypoxia in a mouse model of OSA: effect of tumor microenvironment

Altered CD8+ T-Cell Lymphocyte Function and TC1 Cell Stemness Contribute to Enhanced Malignant Tumor Properties in Murine Models of Sleep Apnea

Analysis of probe level patterns in Affymetrix microarray data

Angiopoietin-2 and soluble Tie-2 receptor plasma levels in children with obstructive sleep apnea and obesity

Aorta macrophage inflammatory and epigenetic changes in a murine model of obstructive sleep apnea: Potential role of CD36.

Catecholamine alterations in pediatric obstructive sleep apnea: effect of obesity

Changes in protein levels of elongation factors, eEF1A-1 and eEF1A-2/S1, in long-term denervated rat muscle

Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice

Circulating Exosomal miRNAs Signal Circadian Misalignment to Peripheral Metabolic Tissues

Circulating Plasma Extracellular Microvesicle MicroRNA Cargo and Endothelial Dysfunction in Children with Obstructive Sleep Apnea

Circulating exosomes in obstructive sleep apnea as phenotypic biomarkers and mechanistic messengers of end-organ morbidity

Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation

Circulating microRNAs as Potential Biomarkers of Endothelial Dysfunction in Obese Children

Circulating plasma exosomes in obstructive sleep apnoea and reverse dipping blood pressure

Cognitive function in prepubertal children with obstructive sleep apnea: a modifying role for NADPH oxidase p22 subunit gene polymorphisms?

DNA Methylation Profiling of Blood Monocytes in Patients With Obesity Hypoventilation Syndrome: Effect of Positive Airway Pressure Treatment

DNA methylation in inflammatory genes among children with obstructive sleep apnea

Development-dependent disappearance of caspase-3 in skeletal muscle is post-transcriptionally regulated

Early intermittent hypoxia induces proatherogenic changes in aortic wall macrophages in a murine model of obstructive sleep apnea

Early-life physical activity reverses metabolic and Foxo1 epigenetic misregulation induced by gestational sleep disturbance

Effect on Intermittent Hypoxia on Plasma Exosomal Micro RNA Signature and Endothelial Function in Healthy Adults

Effects of long-term denervation on skeletal muscle in old rats

Endothelial Dysfunction in Children With Obstructive Sleep Apnea Is Associated With Elevated Lipoprotein-Associated Phospholipase A2 Plasma Activity Levels

Endothelial dysfunction in children with obstructive sleep apnea is associated with epigenetic changes in the eNOS gene

Erratum to “Transcription profiling of estrogen target genes in young and old mouse uterus” [Exp. Gerontol. 38 (2003) 1087–1099]

Evaluation of circulating markers of hepatic apoptosis and inflammation in obese children with and without obstructive sleep apnea

Exosomal miRNAs as potential biomarkers of cardiovascular risk in children

Exosomes and Metabolic Function in Mice Exposed to Alternating Dark-Light Cycles Mimicking Night Shift Work Schedules

Exosomes contribute to endothelial integrity and acute chest syndrome risk: Preliminary findings

Fatty-acid binding protein 4 gene polymorphisms and plasma levels in children with obstructive sleep apnea

Fatty-acid binding protein 4 gene variants and childhood obesity: potential implications for insulin sensitivity and CRP levels

Fragmented sleep accelerates tumor growth and progression through recruitment of tumor-associated macrophages and TLR4 signaling

Genetic variance in nitric oxide synthase and endothelin genes among children with and without endothelial dysfunction

Genetics and Extracellular Vesicles of Pediatrics Sleep Disordered Breathing and Epilepsy ⬇️

Genome-wide gene expression profiling in children with non-obese obstructive sleep apnea

Human adult olfactory neuroepithelial derived progenitors retain telomerase activity and lack apoptotic activity

Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3.

Insulin sensitivity, serum lipids, and systemic inflammatory markers in school-aged obese and nonobese children

Integrated stress response activation by sleep fragmentation during late gestation in mice leads to emergence of adverse metabolic phenotype in offspring

Integrative miRNA-mRNA profiling of adipose tissue unravels transcriptional circuits induced by sleep fragmentation

Intermittent hypoxia activates temporally coordinated transcriptional programs in visceral adipose tissue

Intermittent hypoxia causes NOX2-dependent remodeling of atrial connexins

Intermittent hypoxia mobilizes bone marrow-derived very small embryonic-like stem cells and activates developmental transcriptional programs in mice

Leukocyte telomere length and plasma catestatin and myeloid-related protein 8/14 concentrations in children with obstructive sleep apnea

Lipopolysaccharide-binding protein plasma levels in children: effects of obstructive sleep apnea and obesity

MPrime: efficient large scale multiple primer and oligonucleotide design for customized gene microarrays

Macrophage migration inhibitory factor gene polymorphisms and plasma levels in children with obstructive sleep apnea

Microarray reveals complement components are regulated in the serum-deprived rat retinal ganglion cell line

Nitric oxide production by monocytes in children with OSA and endothelial dysfunction

Obstructive sleep apnea and obesity are associated with reduced GPR 120 plasma levels in children

Plasma Exosomes Disrupt Blood Brain Barrier in Children with OSA and Neurocognitive Deficits

Plasma Exosomes and Improvements in Endothelial Function by Angiotensin 2 Type 1 Receptor or Cyclooxygenase 2 Blockade following Intermittent Hypoxia

Polymorphisms in nitric oxide synthase and endothelin genes among children with obstructive sleep apnea

Prolonged Exposures to Intermittent Hypoxia Promote Visceral White Adipose Tissue Inflammation in a Murine Model of Severe Sleep Apnea: Effect of Normoxic Recovery

Protein-Tyrosine Phosphatase-1B Mediates Sleep Fragmentation-Induced Insulin Resistance and Visceral Adipose Tissue Inflammation in Mice

Serum deprivation induces apoptotic cell death of transformed rat retinal ganglion cells via mitochondrial signaling pathways

Sex dimorphism in late gestational sleep fragmentation and metabolic dysfunction in offspring mice

Sleep fragmentation during late gestation induces metabolic perturbations and epigenetic changes in adiponectin gene expression in male adult offspring mice.

Sleep fragmentation in mice induces nicotinamide adenine dinucleotide phosphate oxidase 2-dependent mobilization, proliferation, and differentiation of adipocyte progenitors in visceral white adipose tissue

Sleep measures and morning plasma TNF-alpha levels in children with sleep-disordered breathing

Stability of Circulating Exosomal miRNAs in Healthy Subjects.

TNF-α gene polymorphisms and excessive daytime sleepiness in pediatric obstructive sleep apnea

Temporal trajectories of novel object recognition performance in mice exposed to intermittent hypoxia

The Challenges of Precision Medicine in Obstructive Sleep Apnea

Transcription profiling of estrogen target genes in young and old mouse uterus

Transcriptional landscape of bone marrow-derived very small embryonic-like stem cells during hypoxia

Transcriptomic Changes of Murine Visceral Fat Exposed to Intermittent Hypoxia at Single Cell Resolution

Transcriptomic analysis identifies phosphatases as novel targets for adenotonsillar hypertrophy of pediatric obstructive sleep apnea

Variants in C-reactive protein and IL-6 genes and susceptibility to obstructive sleep apnea in children: a candidate-gene association study in European American and Southeast European populations