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List of works by Olof Rådmark

1-Oleoyl-2-acetylglycerol stimulates 5-lipoxygenase activity via a putative (phospho)lipid binding site within the N-terminal C2-like domain

scientific article published on 27 May 2005

12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

scientific article

5-Lipoxygenase activation by MAPKAPK-2 and ERKs.

scientific article published in January 2003

5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease

scientific article (publication date: April 2015)

5-Lipoxygenase: mechanisms of regulation

scientific article

5-Lipoxygenase: regulation of expression and enzyme activity

scientific article published on 18 June 2007

5-lipoxygenase-derived leukotrienes: mediators also of atherosclerotic inflammation

scientific article

5-lipoxygenase: regulation and possible involvement in atherosclerosis

scientific article published on 25 January 2007

A mutation interfering with 5-lipoxygenase domain interaction leads to increased enzyme activity

scientific article published on 28 January 2014

Activated LTB4 pathway in muscle tissue of patients with polymyositis or dermatomyositis.

scientific article published on 26 June 2012

Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes

scientific article published in February 2002

Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site

scientific article

Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males

scientific article

Arachidonate 5-lipoxygenase

scientific article

Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2).

scientific article published on 13 February 2002

C-terminus of p47(phox) is required for interaction with leukocyte type rat 12-lipoxygenase

scientific article

Calcitriol upregulates open chromatin and elongation markers at functional vitamin D response elements in the distal part of the 5-lipoxygenase gene

scientific article published on 24 October 2009

Calcium binding to 5-lipoxygenase

scientific article (publication date: 2002)

Caspase-mediated degradation of human 5-lipoxygenase in B lymphocytic cells

scientific article

Cell type-dependent activation of 5-lipoxygenase by arachidonic acid

scientific article published in January 2003

Cloning of rat p47phox and comparison with human p47phox

scientific journal article

Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.

scientific article published on 14 December 2009

Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production

scientific article

ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma

scholarly article

Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration

scientific article published on 21 August 2010

Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids

scientific article published on 04 June 2009

Extracellular signal-regulated kinases phosphorylate 5-lipoxygenase and stimulate 5-lipoxygenase product formation in leukocytes

scientific article published on July 2002

Functional characterization of vitamin D responding regions in the human 5-Lipoxygenase gene

scientific article published on 19 April 2007

GC-rich sequences in the 5-lipoxygenase gene promoter are required for expression in Mono Mac 6 cells, characterization of a novel Sp1 binding site

scientific article published on 27 December 2005

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death

scientific article

Human Dicer C-terminus functions as a 5-lipoxygenase binding domain

scientific article published on 28 October 2008

Hyperforin is a novel type of 5-lipoxygenase inhibitor with high efficacy in vivo.

scientific article

Hypertonicity suppresses ionophore-induced product formation and translocation of 5-lipoxygenase in human leukocytes

scientific article published on March 2002

In vivo sex differences in leukotriene biosynthesis in zymosan-induced peritonitis

scientific article published on 2 June 2014

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

scientific article

Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein

scientific article published on 19 August 2015

Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells

scientific article published on 21 October 2009

Modulation of leukotriene signaling inhibiting cell growth in chronic myeloid leukemia

scientific article published on 8 December 2016

Molecular cloning and functional characterization of mouse coactosin-like protein

scientific article

Monocyte-derived soluble protein confers 5-lipoxygenase activity Ca2+-dependent

scientific article published on July 2002

Mutation analysis of the human 5-lipoxygenase C-terminus: support for a stabilizing C-terminal loop

scientific article published in May 2005

NMR structure of human coactosin-like protein.

scientific article

Necrosis in DU145 prostate cancer spheroids induces COX-2/mPGES-1-derived PGE2 to promote tumor growth and to inhibit T cell activation

scientific article published on 22 April 2013

Novel oxylipins formed from docosahexaenoic acid by potato lipoxygenase--10(S)-hydroxydocosahexaenoic acid and 10,20-dihydroxydocosahexaenoic acid

scientific article published in March 2005

Phosphorylation of serine 523 on 5-lipoxygenase in human B lymphocytes

scientific article published on 24 June 2015

Phosphorylation- and stimulus-dependent inhibition of cellular 5-lipoxygenase activity by nonredox-type inhibitors

scientific article published on 28 March 2003

Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4.

scientific article published on 19 July 2016

Pulmonary sarcoidosis is associated with exosomal vitamin D-binding protein and inflammatory molecules

scientific article

Regulation of 5-lipoxygenase enzyme activity

scientific article

Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis

scientific article published on May 2010

Ribonuclease activity and RNA binding of recombinant human Dicer

scientific article

Role of DNA methylation and methyl-DNA binding proteins in the repression of 5-lipoxygenase promoter activity

scientific article published on 23 September 2009

Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis

scientific article

Stabilisation and characterisation of the isolated regulatory domain of human 5-lipoxygenase

scholarly article by Mirjam Schröder published in October 2014

Structural and Functional Analysis of Calcium Ion Mediated Binding of 5-Lipoxygenase to Nanodiscs

scientific article

Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes ⬇️

scientific article published on June 21, 2011

The C2-like beta-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1.

scientific article

The histone deacetylase inhibitor trichostatin A mediates upregulation of 5-lipoxygenase promoter activity by recruitment of Sp1 to distinct GC-boxes

scientific article published on 17 August 2007

The nuclear RNase III Drosha initiates microRNA processing

scientific article

Thr94 in bovine myelin basic protein is a second phosphorylation site for 42-kDa mitogen-activated protein kinase (ERK2).

scientific article

Time-resolved in situ assembly of the leukotriene-synthetic 5-lipoxygenase/5-lipoxygenase-activating protein complex in blood leukocytes

scientific article published on 22 September 2015

Zymosan suppresses leukotriene C₄ synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors

scientific article published on 12 January 2011

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