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List of works by Jana Gerstmeier

4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)

scholarly article by Erden Banoglu et al published May 2016 in European Journal of Medicinal Chemistry

5-Lipoxygenase-activating protein rescues activity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formation

scientific article published on 3 February 2016

A 5‑lipoxygenase-specific sequence motif impedes enzyme activity and confers dependence on a partner protein

scientific article published on 03 October 2018

Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males

scientific article

BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly

scientific article published on 31 August 2016

Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening

scientific article published on 20 February 2017

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

scientific article published on 4 January 2018

Imbricaric acid and perlatolic acid: multi-targeting anti-inflammatory depsides from Cetrelia monachorum ⬇️

scientific article published in 2013

Inhibition of 5-lipoxygenase as anti-inflammatory mode of action of Plectranthus zeylanicus Benth and chemical characterization of ingredients by a mass spectrometric approach

scientific article published on 27 November 2013

Lipophilic extracts of Leucas zeylanica, a multi-purpose medicinal plant in the tropics, inhibit key enzymes involved in inflammation and gout

scientific article published in May 2018

Munronia pinnata (Wall.) Theob.: unveiling phytochemistry and dual inhibition of 5-lipoxygenase and microsomal prostaglandin E2 synthase (mPGES)-1.

scientific article published on 4 December 2013

Novel leukotriene biosynthesis inhibitors (2012-2016) as anti-inflammatory agents

scientific article published on 22 December 2016

Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase

scientific article published on 24 August 2017

Selective upregulation of TNFα expression in classically-activated human monocyte-derived macrophages (M1) through pharmacological interference with V-ATPase

scientific article published on 8 February 2017

Time-resolved in situ assembly of the leukotriene-synthetic 5-lipoxygenase/5-lipoxygenase-activating protein complex in blood leukocytes

scientific article published on 22 September 2015

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